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- Ding, Xiaoming, et al. Show all 12 Authors
- Gene 2017 v.610 pp. 32-43
- pathophysiology; epigenetics; correlation; ischemia; messenger RNA; DNA methylation; genomic islands; renal failure; DNA; gene expression regulation; kidney transplant; gene expression; tissues; kidneys; exons; introns
- ... Renal ischemia reperfusion injury (IRI) is frequently encountered after kidney transplantation and is a leading cause of acute renal failure. Aberrant gene expression and epigenetic regulation occur during the pathophysiology of IRI. In this study, we used reduced representation bisulfite sequencing to identify the DNA methylome of renal tissues during IRI and the sham-operated tissues in C57BL/6. ...