PubAg

Main content area

You searched for: Author "Epand, Richard M." Remove constraint Author: "Epand, Richard M." Publication Year 2017 Remove constraint Publication Year: 2017 Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
Start Over

Search

2  Search Results

1 - 2 of 2
Number of results to display per page

Search Results

1. Thermodynamics of Methyl-β-cyclodextrin-Induced Lipid Vesicle Solubilization: Effect of Lipid Headgroup and Backbone

Author:
Epand, Richard M.,   et al.   ; Bozelli, José Carlos; Hou, Yu Heng;     Show all 3 Authors
Source:
Langmuir 2017 v.33 no.48 pp. 13882-13891
ISSN:
1520-5827
Subject:
asymmetry; calorimetry; cyclodextrins; energy; engineering; hydrophobicity; light scattering; metabolism; models; phosphatidylcholines; solubility; solubilization; thermodynamics; titration
Abstract:
... The low aqueous solubility of phospholipids makes necessary the use of lipid carriers in studies ranging from lipid traffic and metabolism to the engineering of model membranes bearing lipid transverse asymmetry. One particular lipid carrier that has proven to be particularly useful is methyl-β-cyclodextrin (MβCD). To assess the interaction of MβCD with structurally different phospholipids, the pr ...
DOI:
10.1021/acs.langmuir.7b03447

2. Expression, Purification, and Properties of a Human Arachidonoyl-Specific Isoform of Diacylglycerol Kinase

Author:
Epand, Richard M.,   et al.   ; Jennings, William; Doshi, Sejal; Hota, Prasanta Kumar; Prodeus, Aaron; Black, Stephanie;     Show all 6 Authors
Source:
Biochemistry 2017 v.56 no.9 pp. 1337-1347
ISSN:
1520-4995
Subject:
affinity chromatography; biosynthesis; circular dichroism spectroscopy; diacylglycerol kinase; diacylglycerols; epilepsy; freezing; genes; glycerol; heart diseases; heat; hemolytic uremic syndrome; humans; nickel; phosphorylation; proteins; thawing
Abstract:
... Diacylglycerol kinase ε (DGKε) catalyzes the phosphorylation of diacylglycerol, producing phosphatidic acid. DGKε demonstrates exquisite specificity for the acyl chains of diacylglycerol. This contributes to the enrichment of particular acyl chains within the lipids of the phosphatidylinositol cycle. Phosphatidylinositol is highly enriched with 1-stearoyl-2-arachidonoyl, which is important for mai ...
DOI:
10.1021/acs.biochem.6b01193