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- Bulman, Zackery P., et al. Show all 9 Authors
- International journal of antimicrobial agents 2017 v.49 no.1 pp. 25-30
- Escherichia coli; Gram-negative bacteria; anti-infective agents; antibacterial properties; beta-lactamase; inoculum; microbial growth; multiple drug resistance; pathogens; pharmaceutical industry; pharmacodynamics; plate count; regrowth; simulation models; urinary tract diseases
- ... The proliferation of multidrug-resistant Gram-negative pathogens has been exacerbated by a lack of novel agents in current development by pharmaceutical companies. Ceftolozane/tazobactam was recently approved by the FDA for the treatment of complicated intra-abdominal infections and complicated urinary tract infections. In the present study, the activity of ceftolozane/tazobactam against four isog ...