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- DeMichele, Angela M., et al. Show all 11 Authors
- Cell 2017 v.170 pp. 352-366.e13
- RNA; RNA-binding proteins; blood; breast neoplasms; exosomes; fibroblasts; inflammation; metastasis; neoplasm cells; patients; receptors; stoichiometry; therapeutics
- ... Interactions between stromal fibroblasts and cancer cells generate signals for cancer progression, therapy resistance, and inflammatory responses. Although endogenous RNAs acting as damage-associated molecular patterns (DAMPs) for pattern recognition receptors (PRRs) may represent one such signal, these RNAs must remain unrecognized under non-pathological conditions. We show that triggering of str ...
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