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- Ozmen, Ozlem, et al. Show all 6 Authors
- Yàowù shípǐn fēnxī 2017 v.25 no.4 pp. 890-897
- C-reactive protein; adverse effects; amyloid; anti-inflammatory activity; antioxidants; blood serum; creatinine; epithelial cells; gallic acid; hemorrhage; histopathology; immunohistochemistry; kidneys; males; methotrexate; necrosis; nephrotoxicity; oxidants; oxidative stress; prostaglandins; protective effect; rats; tumor necrosis factor-alpha; urea nitrogen; uric acid
- ... Prolonged use of an antineoplastic agent methotrexate (MTX), can cause numerous side effects such as nephrotoxicity. The aim of this study was to examine the effects of MTX on kidneys and demonstrate the protective effects of gallic acid (GA). Twenty-four, male, rats distributed into three groups. Each groups consisted eight rats and only saline was administered to the control group. The MTX group ...