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1. Structural characterisation of Toll-like receptor 1 (TLR1) and Toll-like receptor 6 (TLR6) in elephant and harbor seals

Author:
Sally Woodman; Amanda J. Gibson; Ana Rubio García; Guillermo Sanchez Contreras; John W. Rossen; Dirk Werling; Victoria Offord
Source:
Veterinary immunology and immunopathology 2016 v.169 pp. 10-14
ISSN:
0165-2427
Subject:
Mirounga; endangered species; methicillin-resistant Staphylococcus aureus; marine mammals; population dynamics; Brucella; risk; Toll-like receptor 6; methicillin; bacterial infections; pathogens; Phoca vitulina; disease outbreaks; mortality; antibiotic resistance; innate immunity; Influenza A virus; environmental health; Phocine morbillivirus; vaccine adjuvants; Toll-like receptor 1
Abstract:
... Pinnipeds are a diverse clade of semi-aquatic mammals, which act as key indicators of ecosystem health. Their transition from land to marine environments provides a complex microbial milieu, making them vulnerable to both aquatic and terrestrial pathogens, thereby contributing to pinniped population decline. Indeed, viral pathogens such as influenza A virus and phocine distemper virus (PDV) have b ...
DOI:
10.1016/j.vetimm.2015.11.006