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- Author:
- N. E. Calatayud; D. M. Shier; R. R. Swaisgood; B. S. Durrant
- Source:
- Reproduction, fertility, and development 2016 v.28 no.2 pp. 189-190
- ISSN:
- 1031-3613
- Subject:
- Rana; adults; air temperature; body weight; breeding; captive animals; dopamine; eggs; females; frogs; gene pool; gonadotropin-releasing hormone; hibernation; males; metoclopramide; oviposition; population; spermiation; tadpoles; urine; zoos
- Abstract:
- ... Severe declines of the mountain yellow-legged frog (MYLF, Rana muscosa) led to establishment of a captive population at the San Diego Zoo Institute for Conservation Research. With less than 200 adults estimated to remain in the wild, the Institute’s MYLF colony currently holds approximately 30% of the entire gene pool. Simulating natural seasonality by artificial brumation and manipulation of atmo ...
- DOI:
- 10.1071/RDv28n2Ab118
- https://doi.org/10.1071/RDv28n2Ab118
- Author:
- I. López-Helguera; P. Whittaker; A. Behrouzi; M. G. Colazo
- Source:
- Reproduction, fertility, and development 2016 v.28 no.2 pp. 135-136
- ISSN:
- 1031-3613
- Subject:
- Holstein; animal health; beef; beef cattle; body weight; cloprostenol; controlled internal drug release devices; corpus luteum; dairy heifers; gonadotropin-releasing hormone; insemination; least squares; periodicity; pregnancy rate; progesterone; semen; sires; ultrasonography
- Abstract:
- ... We have shown that inclusion of initial gonadotropin-releasing hormone (GnRH) in a 5-day Co-synch protocol is unnecessary to achieve acceptable pregnancy rates in dairy heifers (2011 Theriogenology 76, 578). This study determined the efficacy of a modified (without initial GnRH) 5-day Co-synch protocol for timed AI (TAI) and the effect of interval from progesterone device removal to TAI on pregnan ...
- DOI:
- 10.1071/RDv28n2Ab11
- https://doi.org/10.1071/RDv28n2Ab11
- Author:
- W. F. Swanson; H. L. Bateman; J. R. Herrick; L. A. Lyons; L. M. Vansandt
- Source:
- Reproduction, fertility, and development 2016 v.28 no.2 pp. 190-191
- ISSN:
- 1031-3613
- Subject:
- Otocolobus manul; animal care; animal ovaries; artificial insemination; body weight; conception; equine chorionic gonadotropin; females; kittens; males; microsatellite repeats; oviducts; ovulation; paternity; placenta; pregnancy; progeny; relaxin; rivers; semen; spermatozoa; urine; zoos; Central Asia
- Abstract:
- ... The Pallas’ cat, a small-sized felid native to Central Asia, is becoming increasingly threatened in the wild. Their ex situ conservation would benefit from effective assisted reproduction methods, especially AI using frozen semen. In our previous research, we showed that laparoscopic oviductal AI (LO-AI) with low numbers of freshly collected spermatozoa could be used to produce viable offspring in ...
- DOI:
- 10.1071/RDv28n2Ab120
- https://doi.org/10.1071/RDv28n2Ab120
- Author:
- R.A. Matulka; T. Chan; R. Green; J.R. Carney; S. Franklin; P. Licari
- Source:
- Toxicology reports 2016 v.3 pp. 123-134
- ISSN:
- 2214-7500
- Subject:
- Escherichia coli; Garcinia indica; Prototheca moriformis; Salmonella Typhimurium; body weight; bone marrow; chromosome aberrations; diet study techniques; eggs; fermentation; food consumption; food industry; genotoxicity; hematology; histopathology; microalgae; mutagens; mutation; toxicology; urinalysis
- Abstract:
- ... Microalgae are increasingly being utilized as food ingredients for a variety of applications, including as sources of protein, egg and dairy substitutes, and cooking oils. The dietary safety of a new structuring fat produced using a heterotrophic fermentation process by a strain of Prototheca moriformis was evaluated in a 13-week dietary toxicity study and compared with kokum fat, a structuring fa ...
- DOI:
- 10.1016/j.toxrep.2015.12.006
- https://doi.org/10.1016/j.toxrep.2015.12.006
- Author:
- R. Corrêa; J. R. Maio; J. Garcia
- Source:
- Reproduction, fertility, and development 2016 v.28 no.2 pp. 217-218
- ISSN:
- 1031-3613
- Subject:
- Nellore; analysis of variance; blastocyst; body weight; corpus luteum; cross-over studies; embryogenesis; energy metabolism; enzymes; estradiol; estrus; farms; follicle-stimulating hormone; heifers; luteinizing hormone; oocytes; organelles; placebos; progesterone; protein synthesis; veterinary medicine; Brazil
- Abstract:
- ... Ovum pick-up (OPU) and aspirated oocytes produced by in vitro production (IVP) are obtained at random stages of the oestrus cycle and are exposed to different concentrations of oestradiol, progesterone, LH and FSH. These factors may influence the oocyte developmental competence of in vitro embryos. The studies with young females aroused the interest of the investigated for decades and showed that ...
- DOI:
- 10.1071/RDv28n2Ab173
- https://doi.org/10.1071/RDv28n2Ab173
- Author:
- L. G. B. Siqueira; P. Tribulo; A. C. Denicol; M. S. Ortega; V. M. Negrón-Pérez; J. Kannampuzha-Francis; P. J. Hansen
- Source:
- Reproduction, fertility, and development 2016 v.28 no.2 pp. 218
- ISSN:
- 1031-3613
- Subject:
- semen; Holstein; cows; colony-stimulating factors; umbilical cord; risk; carbon dioxide; phenotype; placenta; endometrium; least squares; fetal development; blastocyst; gene expression; zygote; oxygen; bulls; morphometry; body weight; ascites; pregnancy; fetus; conceptus; progeny; USDA; embryo culture; culture media; adverse effects; oocytes; cotyledons; oviducts
- Abstract:
- ... In vitro production (IVP) of embryos can disrupt fetal and placental development and increase risk of abnormal fetal growth. Maternal factors play a role in developmental programming of the early embryo. Colony-stimulating factor 2 (CSF2) is present in the oviduct and endometrium and has improved competence of the pre-implantation embryo to establish pregnancy in cattle. The objective was to deter ...
- DOI:
- 10.1071/RDv28n2Ab175
- https://doi.org/10.1071/RDv28n2Ab175
- Author:
- Magdalena Szyndler-Nędza; Robert Eckert; Tadeusz Blicharski
- Source:
- Annals of animal science 2016 v.16 no.2 pp. 551-564
- ISSN:
- 2300-8733
- Subject:
- correlation; weight gain; gilts; linear models; body weight; equations; meat; ultrasonics; carcass weight; regression analysis; breeds; fat thickness; loins (meat cut); backfat; carcass evaluation
- Abstract:
- ... The aim of the study was to develop new equations for the estimation of meat percentage in the carcasses of young pigs, based on examination of the current pig population. In addition, new regression equations were constructed to predict the weight of meat in primal cuts. In both cases, the estimates were based on performance testing of live animals and post-slaughter evaluation of carcass traits ...
- DOI:
- 10.1515/aoas-2015-0057
- https://doi.org/10.1515/aoas-2015-0057
- Author:
- Kodai Kusakisako; Remil Linggatong Galay; Rika Umemiya-Shirafuji; Emmanuel Pacia Hernandez; Hiroki Maeda; Melbourne Rio Talactac; Naotoshi Tsuji; Masami Mochizuki; Kozo Fujisaki; Tetsuya Tanaka
- Source:
- Parasites & vectors 2016 v.9 no.1 pp. 457
- ISSN:
- 1756-3305
- Subject:
- RNA interference; Haemaphysalis longicornis; ticks; Western blotting; egg weight; genes; blood; oxidative stress; hydrogen peroxide; iron; midgut; gene expression; hatching; oxygen; tissues; messenger RNA; peroxiredoxin; body weight; tick control; larvae; quantitative polymerase chain reaction; proteins; protein synthesis; vertebrates
- Abstract:
- ... BACKGROUND: Ticks are obligate hematophagous arthropods that feed on vertebrate blood that contains iron. Ticks also concentrate host blood with iron; this concentration of the blood leads to high levels of iron in ticks. The host-derived iron reacts with oxygen in the tick body and this may generate high levels of reactive oxygen species, including hydrogen peroxide (H₂O₂). High levels of H₂O₂ ca ...
- DOI:
- 10.1186/s13071-016-1748-2
- PubMed:
- 27542835
- PubMed Central:
- PMC4992251
- https://doi.org/10.1186/s13071-016-1748-2
- Author:
- Zofia Sokołowicz; Józefa Krawczyk; Sylwester Świątkiewicz
- Source:
- Annals of animal science 2016 v.16 no.2 pp. 347-368
- ISSN:
- 2300-8733
- Subject:
- body weight; breast muscle; broiler chickens; capons; chicken breeds; chicken meat; cockerels; color; extensive farming; finishing; genotype; hens; meat production; mixed breeds; polyunsaturated fatty acids; taste
- Abstract:
- ... The objective of the paper was to demonstrate the possibilities of using Polish native breeds of chickens for the production of meat for its specific quality features in the light of worldwide researches. The object of the analysis was the quality of meat from slow-growing chickens raised in varied housing systems, including capons and poulards. The findings of studies on the quality of poultry me ...
- DOI:
- 10.1515/aoas-2016-0004
- https://doi.org/10.1515/aoas-2016-0004
- Author:
- Yen-Chen Tung; Shiming Li; Qingrong Huang; Wei-Lun Hung; Chi-Tang Ho; Guor-Jien Wei; Min-Hsiung Pan
- Source:
- Journal of agricultural and food chemistry 2016 v.64 no.16 pp. 3196-3205
- ISSN:
- 0021-8561
- Subject:
- adenosine; adipogenesis; bioavailability; body weight; cholesterol; citrus peels; enzymes; liver; males; mice; oral administration; polymethoxyflavones; solubility; transcription factors; triacylglycerols
- Abstract:
- ... Polymethoxyflavones (PMFs) and hydroxylated polymethoxyflavones (HPMFs), such as nobiletin (Nob) and 5-demethylnobiletin (5-OH-Nob), are unique flavonoids that are found exclusively in citrus peels. Nobiletin has been shown to suppress adipogenesis in vitro, but the antiadipogenic activity of 5-OH-Nob has not been investigated. Both nobiletin and 5-OH-Nob have poor aqueous solubility and low oral ...
- DOI:
- 10.1021/acs.jafc.6b00706
- https://doi.org/10.1021/acs.jafc.6b00706
- Author:
- Jie Mao; Xing Sun; Jian-Hua Cheng; Yong-Jie Shi; Xin-Zheng Wang; Jun-Jie Qin; Zhi-Hong Sang; Kun He; Qing Xia
- Source:
- Food and chemical toxicology 2016 v.95 pp. 1-11
- ISSN:
- 0278-6915
- Subject:
- Bacillus thuringiensis; Macaca fascicularis; Oryza sativa; blood serum; body temperature; body weight; bovine serum albumin; diet; electrocardiography; electron microscopy; hematology; intestinal microorganisms; metabolome; monkeys; rice; toxicity; toxicology; transgenic plants
- Abstract:
- ... A 52-week feeding study in cynomolgus macaques was carried out to evaluate the safety of Bt rice Huahui 1 (HH1), a transgenic rice line expressing Cry1Ab/1Ac protein. Monkeys were fed a diet with 20% or 60% HH1 rice, 20% or 60% parental rice (Minghui 63, MH63), normal diet, normal diet spiked with purified recombinant Cry1Ab/1Ac fusion protein or bovine serum albumin (BSA) respectively. During the ...
- DOI:
- 10.1016/j.fct.2016.06.015
- https://doi.org/10.1016/j.fct.2016.06.015
- Author:
- Pouya Zamani; Hosein Salehian Dehkordi; Abbas Doosti; Alireza Abdolmohammadi
- Source:
- Annals of animal science 2016 v.16 no.2 pp. 425-438
- ISSN:
- 2300-8733
- Subject:
- beta-globulins; body weight; disease resistance; ewes; exons; gamma-globulins; genotype; immune response; lactose; major histocompatibility complex; marker-assisted selection; milk; serum albumin; single nucleotide polymorphism; single-stranded conformational polymorphism; somatic cell count; weaning
- Abstract:
- ... The DRB1 gene is known as a part of the Major Histocompatibility Complex (MHC) with important effects on disease resistance and immunological response in mammals. Single strand conformational polymorphism (SSCP) analysis and direct DNA sequencing methods were employed to study the second exon of DRB1 gene polymorphism in Mehraban and Lori-Bakhtiari sheep, using 155 Mehraban and 167 Lori-Bakhtiari ...
- DOI:
- 10.1515/aoas-2015-0070
- https://doi.org/10.1515/aoas-2015-0070
- Author:
- Yi-Ming Chen; Li Wei; Yen-Shuo Chiu; Yi-Ju Hsu; Tsung-Yu Tsai; Ming-Fu Wang; Chi-Chang Huang
- Source:
- Nutrients 2016 v.8 no.4 pp. -
- ISSN:
- 2072-6643
- Subject:
- Lactobacillus plantarum; albumins; ammonia; athletic performance; blood serum; body weight; creatine kinase; creatinine; energy; exercise; glucose; health promotion; intestinal microorganisms; lactic acid; males; mice; muscle tissues; muscles; oral administration; probiotics; swimming; triacylglycerols; urea nitrogen
- Abstract:
- ... Lactobacillus plantarum (L. plantarum) is a well-known probiotic among the ingested-microorganism probiotics (i.e., ingested microorganisms associated with beneficial effects for the host). However, few studies have examined the effects of L. plantarum TWK10 (LP10) supplementation on exercise performance, physical fatigue, and gut microbial profile. Male Institute of Cancer Research (ICR) strain m ...
- DOI:
- 10.3390/nu8040205
- PubMed:
- 27070637
- PubMed Central:
- PMC4848674
- https://doi.org/10.3390/nu8040205
- Author:
- Amel M. Soliman; Shreen Desouky; Mohamed Marzouk; Amany A. Sayed
- Source:
- Nutrients 2016 v.8 no.5 pp. -
- ISSN:
- 2072-6643
- Subject:
- Origanum majorana; antioxidant activity; blood; body weight; catalase; cisplatin; creatinine; drug therapy; free radical scavengers; glutathione; males; malondialdehyde; neoplasms; nephrotoxicity; nitric oxide; oxidative stress; plant extracts; rats; superoxide dismutase; urea; urea nitrogen; uric acid
- Abstract:
- ... Despite the fact that cisplatin is an important anticancer drug, its clinical utilization is limited by nephrotoxicity during long term medication. Combined cisplatin chemotherapy with plant extracts can diminish toxicity and enhance the antitumor efficacy of the drug. This study evaluated the effect of Originum majorana ethanolic extract (OMEE) on cisplatin-induced nephrotoxicity. Eighteen male r ...
- DOI:
- 10.3390/nu8050264
- PubMed:
- 27164131
- PubMed Central:
- PMC4882677
- https://doi.org/10.3390/nu8050264
- Author:
- Bianca Bentes da Silva; Jéssica Cristina Souza Silva; Jussara Moretto Martinelli-Lemos; Victoria Judith Isaac Nahum
- Source:
- Biota Amazônia 2016 v.6 no.4 pp. 1-9
- ISSN:
- 2179-5746
- Subject:
- Macrobrachium; allometry; body weight; coasts; dry season; estuaries; females; gonads; morphometry; organic matter; organisms; population dynamics; Brazil
- Abstract:
- ... From Macrobrachium amazonicum (Heller, 1862) (Decapoda, Palaemonidae) abundance in monthly collections in the Amazon estuary and on Mosqueiro Island (State of Pará, Brazil) between April 2006 and August 2007, we verified that the site mentioned is favorable to the development of the species, since there is a significant number of young and adults specimens throughout the year, whose abundance is s ...
- DOI:
- 10.18561/2179-5746/biotaamazonia.v6n4p1-9
- https://doi.org/10.18561/2179-5746/biotaamazonia.v6n4p1-9
- Author:
- Pin-Jun Wan; Yao-Hua Tang; San-Yue Yuan; Wei-Xia Wang; Feng-Xiang Lai; Xiao-Ping Yu; Qiang Fu
- Source:
- Amino acids 2016 v.48 no.11 pp. 2605-2617
- ISSN:
- 0939-4451
- Subject:
- Nilaparvata lugens; RNA interference; adenosine triphosphate; adults; biosynthesis; body weight; essential amino acids; fungi; gene expression; hemolymph; histidine; insects; messenger RNA; pests; rice; sex ratio; symbionts
- Abstract:
- ... Histidine is an essential amino acid assumed to be synthesized by an obligatory yeast-like symbiont (Entomomyces delphacidicola str. NLU) in Nilaparvata lugens, an important rice pest. The adenosine-triphosphate phosphoribosyltransferase (ATP-PRTase) facilities the committed first step of the histidine biosynthesis pathway. In the current study, a putative ATP-PRTase was cloned and verified to be ...
- DOI:
- 10.1007/s00726-016-2287-z
- https://doi.org/10.1007/s00726-016-2287-z
- Author:
- A. E. Huisman; D. J. Brown; N. M. Fogarty
- Source:
- Animal production science 2016 v.56 no.1 pp. 95-101
- ISSN:
- 1836-0939
- Subject:
- Texel; body weight; breeding value; data collection; flocks; genotype; heritability; industry; muscles; phenotype; progeny; purebreds; sheep; sire evaluation; sires; ultrasonics; variance; Australia
- Abstract:
- ... Data used for the genetic evaluation of the terminal sire sheep breeds in Australia originate from a large range of genotypes and environments. This means there are large differences in the level of production and therefore contemporary group means and variances within the data. This study examined four transformations to account for the heterogeneity of variance in the observed data and their eff ...
- DOI:
- 10.1071/AN14666
- https://doi.org/10.1071/AN14666
- Author:
- Yunjiang Yu; Mingdeng Xiang; Dandan Gao; Hao Ye; Qiong Wang; Yanping Zhang; Liangzhong Li; Hui Li
- Source:
- Chemosphere 2016 v.146 pp. 189-194
- ISSN:
- 0045-6535
- Subject:
- absorption; blood serum; body weight; dermal exposure; excretion; feces; flame retardants; laboratory animals; lipids; males; rats; urine
- Abstract:
- ... Tetrabromobisphenol A (TBBPA) is widely used as a flame retardant and frequently detected in environmental and biological samples. In this study, male Wistar rats were repeatedly exposed by dermal application to 20, 60, 200 and 600 mg TBBPA/kg body weight during 90 days. Concentrations of TBBPA in serum, urine and feces after dermal exposure were determined. TBBPA concentrations in serum ranged fr ...
- DOI:
- 10.1016/j.chemosphere.2015.12.027
- https://doi.org/10.1016/j.chemosphere.2015.12.027
- Author:
- Jia‐Long Fang; Michelle Vanlandingham; Gonçalo Gamboa Costa; Frederick A. Beland
- Source:
- Environmental toxicology 2016 v.31 no.5 pp. 609-623
- ISSN:
- 1520-4081
- Subject:
- 2,4-dichlorophenol; absorption; anti-infective agents; body weight; brain; carbon; carcinogenicity; collars; ethanol; excreta; excretion; females; gall bladder; humans; liver; males; medical equipment; metabolism; metabolites; mice; personal care products; propylene glycol; radionuclides; sulfates; tissues; topical application
- Abstract:
- ... Triclosan is used as an antimicrobial agent in personal care products, household items, medical devices, and clinical settings. Humans can receive lifelong exposures to triclosan; however, data on the toxicity and carcinogenicity after topical application are lacking. This study determined the absorption, distribution, metabolism, and excretion of triclosan after application to the skin of B6C3F1 ...
- DOI:
- 10.1002/tox.22074
- https://doi.org/10.1002/tox.22074
- Author:
- Tan Eddie T. T.; Al Jassim Rafat; Cawdell-Smith A. Judy; Ossedryver Selina M.; D’Arcy Bruce R.; Fletcher Mary T.
- Source:
- Journal of agricultural and food chemistry 2016 v.64 no.34 pp. 6622-6629
- ISSN:
- 1520-5118
- Subject:
- Chloris gayana; Indigofera linnaei; Indigofera spicata; barley; biopsy; blood; body weight; camels; cattle; chaff; diet; dietary exposure; dogs; excretion; food safety; grass hay; half life; heart; histopathology; kidneys; liquid chromatography; liver; liver diseases; muscles; necropsy; pancreas; poisoning; rats; sheep; tandem mass spectrometry; tissues; Australia
- Abstract:
- ... Indospicine (l-2-amino-6-amidinohexanoic acid) is a natural hepatotoxin found in all parts of some Indigofera plants such as Indigofera linnaei and Indigofera spicata. Several studies have documented a susceptibility to this hepatotoxin in different species of animals, including cattle, sheep, dogs, and rats, which are associated with mild to severe liver disease after prolonged ingestion. However ...
- DOI:
- 10.1021/acs.jafc.6b02707
- https://doi.org/10.1021/acs.jafc.6b02707
21. Acoustic features within a forest bird community of native and introduced species in New Zealand
- Author:
- Joseph F. Azar; Ben D. Bell
- Source:
- Emu 2016 v.116 no.1 pp. 22-31
- ISSN:
- 1448-5540
- Subject:
- acoustics; birds; body size; body weight; forests; habitats; indigenous species; introduced species; phylogeny; principal component analysis; vocalization; New Zealand
- Abstract:
- ... Habitat-dependent selection pressures may result in convergence of the characteristics of vocalisation of species living in the same habitat, favouring optimal transmission features. However, competitive interactions for acoustic space between different species may lead to divergence of acoustic signals mediated by character displacement. Here, the vocalisations of 16 bird species were examined wi ...
- DOI:
- 10.1071/MU14095
- https://doi.org/10.1071/MU14095
- Author:
- Marta Mesías; Francisco J. Morales
- Source:
- Journal of food composition and analysis 2016 v.48 pp. 8-12
- ISSN:
- 0889-1575
- Subject:
- acrylamides; body weight; coffee (beverage); dietary exposure; ferrocyanides; formic acid; issues and policy; lowest observed effect level; methanol; no observed adverse effect level; potassium; public health; risk; risk assessment; risk communicators; stakeholders; vending machines; zinc acetate
- Abstract:
- ... The present study aimed to evaluate the levels of acrylamide in coffee brews acquired from coffee vending machines. Acrylamide content ranged from 7.7 to 40.0μg/L (mean: 20.6μg/L). These levels are similar to those found in coffee brews prepared by other coffee machines with different extraction procedures. The dietary exposure of the Spanish population to acrylamide through coffee drinks was esti ...
- DOI:
- 10.1016/j.jfca.2016.02.005
- https://doi.org/10.1016/j.jfca.2016.02.005
- Author:
- Nevena Ivanovic; Rajna Minic; Ivana Djuricic; Sanja Radojevic Skodric; Irena Zivkovic; Sladjana Sobajic; Brizita Djordjevic
- Source:
- Food & function 2016 v.7 no.6 pp. 2840-2848
- ISSN:
- 2042-650X
- Subject:
- Lactobacillus plantarum; Lactobacillus rhamnosus; body weight; brain; fatty acid composition; fatty liver; heart; heart diseases; high energy diet; high fat diet; hypercholesterolemia; insulin resistance; lifestyle; liver; mice; probiotics; tissues; triacylglycerols
- Abstract:
- ... Western life style, and high calorie diet in particular is causing major health problems such as insulin resistance, hepatic steatosis and heart disease in the modern age. High fat diet (HFD) induces similar changes in mice, such as increased body weight, hypercholesterolemia and accumulation of triglycerides in the liver. These changes can be ameliorated by the administration of some Lactobacillu ...
- DOI:
- 10.1039/c5fo01432h
- https://doi.org/10.1039/c5fo01432h
- Author:
- S. Roy; B. Ukil; L.M. Lyndem; Hani El-Nezami
- Source:
- Cogent biology 2016 v.2 no.1 pp. 1272166
- ISSN:
- 2331-2025
- Subject:
- Senna alata; acute toxicity; albino; body weight; histopathology; kidneys; leaf extracts; leaves; liver; mortality; oral administration; spleen
- Abstract:
- ... Senna alata has attracted the attention of many researchers due to its numerous medicinal properties. This study aims to test the acute and sub-acute toxicity of its leaf extracts in Swiss albino mice. Studies were carried out with a fixed dose of 1,000, 2,000, and 3,000 mg/kg body weight through oral administration daily. Signs of toxicity in terms of behavior and mortality were noted after every ...
- DOI:
- 10.1080/23312025.2016.1272166
- https://doi.org/10.1080/23312025.2016.1272166
- Author:
- Róbert Kovács; Katalin Bakos; Béla Urbányi; Judit Kövesi; Gyöngyi Gazsi; Andrea Csepeli; Ádám János Appl; Dóra Bencsik; Zsolt Csenki; Ákos Horváth
- Source:
- Environmental science and pollution research international 2016 v.23 no.15 pp. 14718-14729
- ISSN:
- 0944-1344
- Subject:
- Danio rerio; adults; body weight; cisplatin; etoposide; fish; fluorouracil; guidelines; larvae; lethal concentration 50; mortality; toxicity
- Abstract:
- ... The acute and sub-chronic effects of four cytostatic drugs—5-fluorouracil (5-FU), cisplatin (CisPt), etoposide (ET) and imatinib mesylate (IM)—on zebrafish (Danio rerio) were investigated. Acute tests were carried out in a static system in accordance with the OECD guideline 203 for adult fish and the draft guideline for fish embryos (FET test) in order to find the LC50 values of the four cytostati ...
- DOI:
- 10.1007/s11356-015-5036-z
- https://doi.org/10.1007/s11356-015-5036-z
- Author:
- Eunsook Park; Mee-Young Lee; Chang-Seob Seo; Sae-Rom Yoo; Woo-Young Jeon; Hyeun-Kyoo Shin
- Source:
- BMC complementary and alternative medicine 2016 v.16 no.1 pp. 370
- ISSN:
- 1472-6882
- Subject:
- acute toxicity; adverse effects; alternative medicine; blood serum; body weight; cytotoxicity; epithelium; females; fungi; hematology; hyperplasia; lethal dose; males; medicinal plants; mortality; oral administration; rats; salivation; subacute toxicity; urinalysis; viability; Korean Peninsula
- Abstract:
- ... BACKGROUND: Melandrii Herba, a medicinal plant, has been used in Korea for treatment of bacterial and fungal infection. However, the safety and toxicity of Melandrii Herba have not yet been established. Therefore, we investigated the acute and subacute toxicity of an ethanolic extract of Melandrii Herba (MHEE) in Crl:CD Sprague Dawley rats and cytotoxicity of MHEE in vitro. METHODS: To study acute ...
- DOI:
- 10.1186/s12906-016-1342-3
- PubMed:
- 27659845
- PubMed Central:
- PMC5034513
- https://doi.org/10.1186/s12906-016-1342-3
- Author:
- Sara Emilia Lima Tolouei Menegati; Fernando Freitas de Lima; Giseli Karenina Traesel; Roosevelt Isaias Carvalho Souza; Ariany Carvalho dos Santos; Diana Figueiredo de Santana Aquino; Vinícius Soares de Oliveira; Silvia Cristina Heredia Vieira; Claudia Andrea Lima Cardoso; Maria do Carmo Vieira; Silvia Aparecida Oesterreich
- Source:
- Journal of ethnopharmacology 2016 v.194 pp. 1096-1102
- ISSN:
- 0378-8741
- Subject:
- acute toxicity; behavior change; blood sampling; body weight; cerrado; clinical trials; death; females; guidelines; histopathology; humans; indigenous species; leaves; lethal dose 50; males; plants (botany); rats; satellites; screening; subacute toxicity; tea; toxicity testing; traditional medicine
- Abstract:
- ... Alibertia edulis, popularly known as “marmelo do Cerrado” is a native plant from the brazilian Cerrado. It has high food and ornamental potential and the tea leaves are currently used as hypoglycemic, antihypertensive and diuretic.In order to evaluate the safety of the aqueous extract of Alibertia edulis leaves (AEAE), the acute and subacute toxicity tests were performed in male and female Wistar ...
- DOI:
- 10.1016/j.jep.2016.11.003
- https://doi.org/10.1016/j.jep.2016.11.003
- Author:
- Eduardo Gregolin Moretti; Veronica Quispe Yujra; Samuel Rangel Claudio; Marcelo Jose Dias Silva; Wagner Vilegas; Camilo Dias Seabra Pereira; Flavia de Oliveira; Daniel Araki Ribeiro
- Source:
- Environmental science and pollution research international 2016 v.23 no.8 pp. 8104-8112
- ISSN:
- 0944-1344
- Subject:
- acute exposure; blood; body weight; bone marrow cells; cocaine; gels; hepatocytes; immunohistochemistry; rats; toxicity
- Abstract:
- ... Crack cocaine is a very toxic product derived from cocaine. The aim of this study was to evaluate genetic damage in multiple organs of rats following acute exposure to crack cocaine. A total of 20 Wistar rats were distributed into four groups (n = 5), as follows: 0, 4.5, 9, and 18 mg/kg body weight (b.w.) of crack cocaine administered by intraperitoneal route (i.p.). All animals were killed 24 h a ...
- DOI:
- 10.1007/s11356-016-6141-3
- https://doi.org/10.1007/s11356-016-6141-3
- Author:
- Wenqing Tu; Chao Xu; Bin Lu; Chunmian Lin; Yongming Wu; Weiping Liu
- Source:
- Science of the total environment 2016 v.542 pp. 876-885
- ISSN:
- 0048-9697
- Subject:
- Danio rerio; acute exposure; bifenthrin; bioaccumulation; body condition; body weight; endocrine system; fish; gene expression regulation; genes; lambda-cyhalothrin; larvae; mammals; molecular models; pyrethrins; signal transduction; thyroid hormone receptors; transcription (genetics); triiodothyronine
- Abstract:
- ... Synthetic pyrethroids (SPs) have the potential to disrupt the thyroid endocrine system in mammals; however, little is known of the effects of SPs and underlying mechanisms in fish. In the current study, embryonic zebrafish were exposed to various concentrations (1, 3 and 10μg/L) of bifenthrin (BF) or λ-cyhalothrin (λ-CH) until 72h post fertilization, and body condition, bioaccumulation, thyroid ho ...
- DOI:
- 10.1016/j.scitotenv.2015.10.131
- https://doi.org/10.1016/j.scitotenv.2015.10.131
- Author:
- Flávia Cristina Morone Pinto; Ana Cecília A.X. De-Oliveira; Rosangela R. De-Carvalho; Maria Regina Gomes-Carneiro; Deise R. Coelho; Salvador Vilar C. Lima; Francisco José R. Paumgartten; José Lamartine A. Aguiar
- Source:
- Carbohydrate polymers 2016 v.137 pp. 556-560
- ISSN:
- 0144-8617
- Subject:
- acute toxicity; adults; body weight; cell culture; cell death; culture media; cytotoxicity; exopolysaccharides; females; genotoxicity; hepatoma; lactate dehydrogenase; males; molasses; rats; sugarcane
- Abstract:
- ... The acute toxicity, cytotoxicity, genotoxicity and antigenotoxic effects of BC were studied. Cytotoxicity of BC was evaluated in cultured C3A hepatoma cells (HepG2/C3A) using a lactate dehydrogenase (LDH) activity assay. Acute toxicity was tested in adults Wistar rats treated with a single dose of BC. The genotoxicity of BC was evaluated in vivo by the micronucleus assay. BC (0.33–170μg/mL) added ...
- DOI:
- 10.1016/j.carbpol.2015.10.071
- https://doi.org/10.1016/j.carbpol.2015.10.071
- Author:
- A. Scala; G. Urrai; A. Varcasia; P. Nicolussi; M. Mulas; L. Goddi; A.P. Pipia; G. Sanna; M. Genchi; E. Bandino
- Source:
- Journal of helminthology 2016 v.90 no.1 pp. 113-116
- ISSN:
- 1475-2697
- Subject:
- Taenia hydatigena; body weight; cysticercosis; death; females; hepatitis; histology; lambs; mortality; necropsy; praziquantel
- Abstract:
- ... An acute outbreak of Taenia hydatigena cysticercosis, causing mortality in 5 of 21 (23.8%) female lambs, is reported. Gross post-mortem examinations and histology showed Cysticercus tenuicollis as the cause of death. Biochemical parameters in infected lambs confirmed severe hepatitis. Praziquantel, given once at 15 mg/kg body weight (bw), was administered and a dramatic improvement in the clinical ...
- DOI:
- 10.1017/S0022149X14000601
- PubMed:
- 25120032
- https://doi.org/10.1017/S0022149X14000601
- Author:
- Joan SerranoThese authors contributed equally to this work.; Àngela Casanova-Martí; Katherine Gil-Cardoso; M. Teresa Blay; Ximena Terra; Montserrat Pinent; Anna Ardévol
- Source:
- Food & function 2016 v.7 no.1 pp. 483-490
- ISSN:
- 2042-650X
- Subject:
- body weight; cholecystokinin; food intake; gastric emptying; gastrointestinal system; ghrelin; glucagon-like peptide 1; laboratory animals; proanthocyanidins; rats
- Abstract:
- ... Grape-seed proanthocyanidins’ role as stimulators of active GLP-1 in rats suggests that they could be effective as satiating agents. Wistar rats were used to study the effects of proanthocyanidins on food intake with different doses, administration times and proanthocyanidin extract compositions. A dose of 423 mg of phenolics per kg body weight (BW) of grape-seed proanthocyanidin extract (GSPE) wa ...
- DOI:
- 10.1039/c5fo00892a
- https://doi.org/10.1039/c5fo00892a
- Author:
- Shaji Shilja; V. Sejian; M. Bagath; A. Mech; C. G. David; E. K. Kurien; Girish Varma; Raghavendra Bhatta
- Source:
- International journal of biometeorology 2016 v.60 no.9 pp. 1311-1323
- ISSN:
- 0020-7128
- Subject:
- adults; analysis of variance; bioclimatology; biomarkers; body weight; bucks; drinking; gene expression; goats; head; heart rate; heat; heat stress; heat-shock protein 70; malnutrition; messenger RNA; mononuclear leukocytes; physiological response; respiratory rate; restricted feeding; scrotum; skin temperature; solar radiation
- Abstract:
- ... A study was conducted to assess the impact of heat and nutritional stress simultaneously on the adaptive capability as indicated by behavioral and physiological responses, plasma heat shock protein 70 (HSP70) level, and peripheral blood mononuclear cells (PBMC) HSP70 gene expression in goats. Twenty-four adult Osmanabadi bucks (average body weight (BW) 16.0 kg) were used in the present study. The ...
- DOI:
- 10.1007/s00484-015-1124-5
- https://doi.org/10.1007/s00484-015-1124-5
- Author:
- Sony S Thazhath; Tongzhi Wu; Michelle J Bound; Helen L Checklin; Scott Standfield; Karen L Jones; Michael Horowitz; Christopher K Rayner
- Source:
- American journal of clinical nutrition 2016 v.103 no.1 pp. 66-70
- ISSN:
- 1938-3207
- Subject:
- animal models; blood glucose; body weight; breath tests; cross-over studies; energy intake; food records; gastric emptying; glucagon; glucagon-like peptide 1; glycemic control; glycohemoglobin; insulin secretion; noninsulin-dependent diabetes mellitus; patients; placebos; randomized clinical trials; resveratrol
- Abstract:
- ... Background: Resveratrol has been reported to lower glycemia in rodent models of type 2 diabetes associated with the stimulation of glucagon-like peptide 1 (GLP-1), which is known to slow gastric emptying, stimulate insulin secretion, and suppress glucagon secretion and energy intake. Objective: We evaluated the effects of 5 wk of resveratrol treatment on GLP-1 secretion, gastric emptying, and glyc ...
- DOI:
- 10.3945/ajcn.115.117440
- https://doi.org/10.3945/ajcn.115.117440
- Author:
- Adrian R. James; Matthew T. Harrison
- Source:
- Animal production science 2016 v.56 no.3 pp. 393-401
- ISSN:
- 1836-0939
- Subject:
- body weight; case studies; emissions factor; ewes; farmers; farming systems; farms; finishing; flocks; greenhouse gas emissions; greenhouse gases; high fat diet; industry; liveweight gain; meat; models; pastures; proanthocyanidins; range livestock; reproductive efficiency; rumen; slaughter; surveys; wool production; Tasmania
- Abstract:
- ... Significant research has been conducted on greenhouse gas emissions mitigation techniques for ruminant livestock farming, however putting these techniques into practice on-farm requires consideration of adoptability by livestock producers. We modelled the adoptability of a range of livestock greenhouse gas abatement techniques using data from farm case studies and industry surveys, then compared t ...
- DOI:
- 10.1071/AN15578
- https://doi.org/10.1071/AN15578
- Author:
- Guanyu Hu; Zhou Fang; Bilin Liu; Dan Yang; Xinjun Chen; Yong Chen
- Source:
- Fisheries science 2016 v.82 no.4 pp. 597-604
- ISSN:
- 0919-9268
- Subject:
- Dosidicus gigas; animal age; animal growth; autumn; beak; body weight; females; gender differences; hatching; males; microstructure; population structure; spawning; squid; summer
- Abstract:
- ... The beak is a hard structure of cephalopods with relatively constant shape, which records a lot of biological and ecological information. Based on samples collected by Chinese squid jigging vessels off the Peruvian Exclusive Economic Zone from July to October 2013, we explored the feasibility of age estimation and growth pattern with the upper beak of Dosidicus gigas. The internal rostral axis and ...
- DOI:
- 10.1007/s12562-016-0991-y
- https://doi.org/10.1007/s12562-016-0991-y
- Author:
- Hisaka Kurita; Vinicius S. Carreira; Yunxia Fan; Min Jiang; Mindi Naticchioni; Sheryl Koch; Jack Rubinstein; Alvaro Puga
- Source:
- Toxicology 2016 v.355-356 pp. 9-20
- ISSN:
- 0300-483X
- Subject:
- adults; blood pressure; body weight; calcium signaling; cardiomyocytes; epidemiological studies; females; fibrosis; gene expression; genes; heart diseases; humans; hypertrophy; knockout mutants; males; mice; myosin; sexual dimorphism; tetrachlorodibenzo-p-dioxin; toxicity
- Abstract:
- ... Epidemiological studies in humans and experimental work in rodents suggest that exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a persistent environmental toxicant, is associated with incidence of heart disease. Although TCDD toxicity depends by and large on the aryl hydrocarbon receptor (AHR), the role of the cardiac AHR in TCDD induced cardiovascular disease is not well defined. To deter ...
- DOI:
- 10.1016/j.tox.2016.05.006
- https://doi.org/10.1016/j.tox.2016.05.006
- Author:
- Shalini Mohan; Kalaivani Thiagarajan; Balaji Sundaramoorthy; Vivek Gurung; Manas Barpande; Shilpi Agrawal; Rajasekaran Chandrasekaran
- Source:
- BMC complementary and alternative medicine 2016 v.16 no.1 pp. 229
- ISSN:
- 2662-7671
- Subject:
- Oroxylum indicum; albino; alternative medicine; anti-inflammatory activity; antioxidant activity; antioxidants; bioactive compounds; blood serum; body weight; dose response; drinking water; humans; leaf extracts; lipid peroxidation; lipids; liver; mutagens; neoplasms; oral administration; oxidative stress; rats
- Abstract:
- ... BACKGROUND: 4-nitroquinoline 1-oxide (4-NQO) is a mutagen known to be responsible for causing cancer by generating oxidative stress in humans. Oroxylum indicum (L.) possesses various bioactive compounds with antioxidant properties. In this connection, the present study aims to analyze the alleviation of 4-NQO induced oxidative stress in albino Wistar rats using O. indicum (L.) leaf extract. METHOD ...
- DOI:
- 10.1186/s12906-016-1186-x
- PubMed:
- 27430309
- PubMed Central:
- PMC4950254
- https://doi.org/10.1186/s12906-016-1186-x
- Author:
- David J. Cottle; Annette L. Cowie
- Source:
- international journal of life cycle assessment 2016 v.21 no.6 pp. 820-830
- ISSN:
- 0948-3349
- Subject:
- Merino; attributional life cycle assessment; body weight; climatic zones; coproducts; crossbreds; dry season; ewes; farmers; farms; flocks; greenhouse gas emissions; greenhouse gases; interviews; inventories; production technology; protein content; sheep meat; simulation models; summer; wethers; wool; wool production; Australia
- Abstract:
- ... PURPOSE: Australia is the largest supplier of high-quality wool in the world. The environmental burden of sheep production must be shared between wool and meat. We examine different methods to handle these co-products and focus on proportional protein content as a basis for allocation, that is, protein mass allocation (PMA). This is the first comprehensive investigation applying PMA for calculatin ...
- DOI:
- 10.1007/s11367-016-1054-4
- https://doi.org/10.1007/s11367-016-1054-4
- Author:
- Alberto Sabbioni; Valentino Beretti; Federico Righi; Paola Superchi
- Source:
- Small ruminant research 2016 v.144 pp. 248-254
- ISSN:
- 0921-4488
- Subject:
- allometry; analysis of variance; autumn; body weight; chest; ears; flocks; head; ileum; lactating females; lactation; lambing; lambs; linear models; males; meat production; morphometry; open range; pastures; range management; slaughter; spring; weaning; winter; withers
- Abstract:
- ... With the aim to find indirect parameters for meat production that potentially could be used for selective purposes in Cornigliese sheep breed, 368 animals were weighed and measured (16 linear measures) during two years in 4 flocks with pasture and open range management from spring to autumn and closed facilities during winter. An amount of 0.2–0.4kg/head/day of the same concentrate was provided to ...
- DOI:
- 10.1016/j.smallrumres.2016.10.005
- https://doi.org/10.1016/j.smallrumres.2016.10.005
- Author:
- B.A. McGregor
- Source:
- Small ruminant research 2016 v.145 pp. 28-32
- ISSN:
- 0921-4488
- Subject:
- Angora (goat breed); allometry; body condition; body length; body weight; fleece; goats; linear models; mohair; physical properties; prediction; slaughter; surface area; variance; winter
- Abstract:
- ... This study aimed to determine the relationships between skin surface area, animal size and mohair physical properties using estimates of skin area determined on animals prior to slaughter and to compare these with skin weight and skin area determined after slaughter. Angora kids born in late winter were shorn at 18 weeks of age. Prior to slaughter at 20 weeks of age, 15 kids of each sex were ident ...
- DOI:
- 10.1016/j.smallrumres.2016.10.018
- https://doi.org/10.1016/j.smallrumres.2016.10.018
- Author:
- Lanting Ma; Ying Wang; Weixing Zhang; Hongfang Wang; Zhenguo Liu; Baohua Xu
- Source:
- Journal of Asia-Pacific entomology 2016 v.19 no.3 pp. 769-774
- ISSN:
- 1226-8615
- Subject:
- Apis mellifera; alanine transaminase; amino acid metabolism; amino acids; animals; aspartate transaminase; body weight; cholesterol; creatine kinase; crystals; genes; hemolymph; honey bees; instars; lactate dehydrogenase; larvae; protein bodies; protein content; protein synthesis; triacylglycerols; urea nitrogen; uric acid
- Abstract:
- ... l-Leucine is an important factor for growth and development in animals. However, very little is known about the nutritional role and physiological function of l-leucine in honeybees. In this study, we determined the effects of l-leucine supplementation on protein synthesis and amino acid balance in honeybee larvae. First instar larvae were fed different l-leucine diets (6.45, 8.45 and 10.45mg/g) d ...
- DOI:
- 10.1016/j.aspen.2016.07.005
- https://doi.org/10.1016/j.aspen.2016.07.005
- Author:
- P.J. Gorden; M.D. Kleinhenz; L.W. Wulf; B. KuKanich; C.J. Lee; C. Wang; J.F. Coetzee
- Source:
- Journal of dairy science 2016 v.99 no.1 pp. 505-514
- ISSN:
- 0022-0302
- Subject:
- blood; body weight; ceftiofur; dairy cows; drugs; half life; liquid chromatography; mass spectrometry; mastitis; meat; milk yield; models; pharmacokinetics; risk; therapeutics
- Abstract:
- ... Mastitis is a frequent problem among dairy cows, reducing milk yield and increasing cull rates. Systemic therapy with the cephalosporin antimicrobial ceftiofur hydrochloride (CEF) may improve therapeutic outcomes, but the incidence of CEF violative residues has increased annually since 2011. One potential explanation is that disease status may alter the pharmacokinetics (PK) of CEF. To test this h ...
- DOI:
- 10.3168/jds.2015-10239
- https://doi.org/10.3168/jds.2015-10239
- Author:
- Patricia López; Dini Venema; Hans Mol; Martien Spanjer; Joyce de Stoppelaar; Erika Pfeiffer; Monique de Nijs
- Source:
- Food control 2016 v.69 pp. 153-159
- ISSN:
- 0956-7135
- Subject:
- Alternaria; Helianthus annuus; autumn; body weight; figs; foods; seeds; surveys; tenuazonic acid; tomato products; toxins; Netherlands
- Abstract:
- ... A survey on Alternaria toxins in the food categories dried figs (n = 14), sunflower products (n = 24) and tomato products (n = 43) was carried out in the Netherlands on samples collected in retail stores in autumn 2014. The occurrence data from this survey confirmed the previously reported data of a pilot survey in 2013, with tenuazonic acid being an ubiquitous Alternaria toxin in dried figs (100% ...
- DOI:
- 10.1016/j.foodcont.2016.04.001
- https://doi.org/10.1016/j.foodcont.2016.04.001
- Author:
- Xi Li; Kazuhiko Higashida; Takuji Kawamura; Mitsuru Higuchi
- Source:
- Nutrients 2016 v.8 no.4 pp. -
- ISSN:
- 2072-6643
- Subject:
- body weight; citrate (si)-synthase; energy intake; enzyme activity; epididymis; fatigue strength; glucose transporters; glycogen; high fat diet; laboratory animals; males; metabolic syndrome; mitochondria; muscles; nutritional intervention; protein content; rats; skeletal muscle
- Abstract:
- ... Long-term high-fat diet increases muscle mitochondrial enzyme activity and endurance performance. However, excessive calorie intake causes intra-abdominal fat accumulation and metabolic syndrome. The purpose of this study was to investigate the effect of an alternating day high-fat diet on muscle mitochondrial enzyme activities, protein content, and intra-abdominal fat mass in rats. Male Wistar ra ...
- DOI:
- 10.3390/nu8040203
- PubMed:
- 27058555
- PubMed Central:
- PMC4848672
- https://doi.org/10.3390/nu8040203
- Author:
- Imen Ghorbel; Ibtissem Ben Amara; Naourez Ktari; Awatef Elwej; Ons Boudawara; Tahia Boudawara; Najiba Zeghal
- Source:
- Biological trace element research 2016 v.174 no.2 pp. 335-346
- ISSN:
- 0163-4984
- Subject:
- acrylamides; adenosinetriphosphatase; adults; advanced oxidation protein products; adverse effects; aluminum; ascorbic acid; body weight; catalase; cerebellum; drinking water; females; humans; lactation; malondialdehyde; mothers; neurotoxicity; pregnancy; progeny; pups; rats; suckling; superoxide dismutase; synergism; toxic substances
- Abstract:
- ... Accumulation of aluminium and acrylamide in food is a major source of human exposure. Their adverse effects are well documented, but there is no information about the health problems arising from their combined exposure. The aim of the present study was to examine the possible neurotoxic effects after co-exposure of pregnant and lactating rats to aluminium and acrylamide in order to evaluate redox ...
- DOI:
- 10.1007/s12011-016-0716-1
- https://doi.org/10.1007/s12011-016-0716-1
- Author:
- Mami Ogimoto; Kumi Suzuki; Nahoko Haneishi; Yuu Kikuchi; Mayu Takanashi; Naoko Tomioka; Yoko Uematsu; Kimio Monma
- Source:
- Food additives & contaminants 2016 v.9 no.3 pp. 185-190
- ISSN:
- 1939-3229
- Subject:
- Food and Agriculture Organization; World Health Organization; aluminum; body weight; children; cookies; food additives; food safety
- Abstract:
- ... Aluminium (Al) levels of 90 food samples were investigated. Nineteen samples contained Al levels exceeding the tolerable weekly intake (TWI) for young children [body weight (bw): 16 kg] when consuming two servings/week. These samples were purchased multiple times at specific intervals and were evaluated for Al levels. Al was detected in 27 of the 90 samples at levels ranging from 0.01 (limit of qu ...
- DOI:
- 10.1080/19393210.2016.1158210
- https://doi.org/10.1080/19393210.2016.1158210
- Author:
- Qiuyue Zhang; Zheng Cao; Xudong Sun; Cuicui Zuang; Wanyue Huang; Yanfei Li
- Source:
- Biological trace element research 2016 v.171 no.1 pp. 116-123
- ISSN:
- 0163-4984
- Subject:
- Ca2-transporting ATPase; aluminum; aluminum chloride; blood pressure; body weight; catalase; erythrocytes; glutathione peroxidase; hypertension; lethal dose 50; males; malondialdehyde; membrane potential; rats; risk; superoxide dismutase
- Abstract:
- ... Aluminum (Al) is the most abundant metal in the earth’s crust. Al accumulates in erythrocyte and causes toxicity on erythrocyte membrane. The dysfunction of erythrocyte membrane is a potential risk to hypertension. The high Al content in plasma was associated with hypertension. To investigate the effect of AlCl₃ on blood pressure and the function of erythrocyte membrane, the rats were intragastric ...
- DOI:
- 10.1007/s12011-015-0504-3
- https://doi.org/10.1007/s12011-015-0504-3
- Author:
- Heba M.A. Abdelrazek; Seham A. Helmy; Doaa H. Elsayed; Hala M. Ebaid; Racha M. Mohamed
- Source:
- Reproductive Biology 2016 v.16 no.4 pp. 300-308
- ISSN:
- 1642-431X
- Subject:
- adverse effects; androgen receptors; apoptosis; body weight; cadmium; cadmium chloride; caspase-3; catalase; cholesterol; endocrine-disrupting chemicals; enzyme activity; epididymis; glutathione; green tea; hypercholesterolemia; male fertility; males; prostate gland; protective effect; protein synthesis; rats; spermatozoa; superoxide dismutase; testes
- Abstract:
- ... Cadmium is one of the potent environmental endocrine disruptors that has adverse effects on male fertility. This study was conducted to investigate the protective role of green tea extract (GTE) on cadmium chloride (CdCl2) induced reproductive toxicities in male Wistar rats. Thirty-six male Wistar rats were divided to 4 groups, each one contained 9 rats. Control group, they were gavaged distilled ...
- DOI:
- 10.1016/j.repbio.2016.11.001
- https://doi.org/10.1016/j.repbio.2016.11.001
- Author:
- Ashish Kumar Jena; Karan Vasisht; Neetika Sharma; Ramdeep Kaur; Mamta Sachdeva Dhingra; Maninder Karan
- Source:
- Journal of ethnopharmacology 2016 v.190 pp. 33-45
- ISSN:
- 0378-8741
- Subject:
- Convention on International Trade in Endangered Species; Prunus africana; Prunus armeniaca; Prunus cerasoides; Prunus domestica; Prunus dulcis; Prunus persica; antioxidant activity; antioxidants; bark; beta-sitosterol; body weight; creatinine; histopathology; hyperplasia; immunohistochemistry; laboratory animals; men; proliferating cell nuclear antigen; protective effect; rats; testes; testosterone; traditional medicine; ursolic acid; Africa
- Abstract:
- ... Benign prostatic hyperplasia (BPH) is a common urological disorder of men. The ethnomedicinal use of an African plant Prunus africana (Hook.f.) Kalkman (Pygeum) in treating men's problems made it a popular remedy all over the globe for the treatment of BPH and related disorders. However, rampant collections made from the wild in Africa have pushed the plant to Appendix II of CITES demanding conser ...
- DOI:
- 10.1016/j.jep.2016.05.052
- https://doi.org/10.1016/j.jep.2016.05.052
- Author:
- Naila Chand; Sher Muhammad; Rifat Ullah Khan; Ibrahim Abdullah Alhidary; Zia ur Rehman
- Source:
- Environmental science and pollution research international 2016 v.23 no.23 pp. 23930-23935
- ISSN:
- 0944-1344
- Subject:
- Newcastle disease; antioxidants; aryldialkylphosphatase; body weight; broiler chickens; diet; feed conversion; feed intake; gamma-aminobutyric acid; heat stress; immune response; males; malondialdehyde; summer
- Abstract:
- ... The aim of this study was to find the effect of synthetic γ-aminobutyric acid (GABA) on the performance, antioxidant status, and immune response in broiler exposed to summer stress. A total of 400-day-old male broiler chickens (Ross 308) was randomly distributed into five treatments (5 replicates). One group served as a control (basal diet only) while the others were supplemented with GABA at the ...
- DOI:
- 10.1007/s11356-016-7604-2
- https://doi.org/10.1007/s11356-016-7604-2
- Author:
- Miroslav Popper; Soňa Gancarčíková; Marián Maďar; Dagmar Mudroňová; Gabriela Hrčková; Radomíra Nemcová
- Source:
- Applied microbiology and biotechnology 2016 v.100 no.22 pp. 9671-9682
- ISSN:
- 0175-7598
- Subject:
- Enterococcus; Escherichia coli; amoxicillin; animal health; animal models; aseptic conditions; body weight; cecum; ciprofloxacin; feces; females; genetic databases; germ-free animals; health status; intestinal microorganisms; mice; oral administration; potassium; species diversity; subcutaneous injection; Slovenia; Spain
- Abstract:
- ... The experiment was carried out on 24 SPF BALB/c female mice and lasted for 15 days with a 5-day antibiotic (ATB) treatment and then 10 days without ATB treatment. The aim of our study was to acquire an animal model with reduced and controlled microflora and, at the same time, to ensure that the good health of these animals is maintained. Per oral administration of amoxicillin and clavulanate potas ...
- DOI:
- 10.1007/s00253-016-7855-3
- https://doi.org/10.1007/s00253-016-7855-3
- Author:
- Zohreh Khodadadian; Majid Hassanpour-Ezatti; Seyed Zahra Mousavi; Jinous Asgarpanah
- Source:
- Asian Pacific Journal of Tropical Biomedicine 2016 v.6 pp. 198-201
- ISSN:
- 2221-1691
- Subject:
- Daphne; aerial parts; analgesia; analgesic effect; anti-inflammatory activity; anti-inflammatory agents; body weight; ethyl acetate; formalin; formalin test; morphine; naloxone; pain; receptors
- Abstract:
- ... To investigate the analgesic and anti-inflammatory property and possible involvement of opioid receptors of ethyl acetate extract from aerial parts of Daphne mucronata (D. mucronata) in mice by formalin test.Single doses of 2.5, 5.0 and 10.0 mg/kg of body weight of ethyl acetate extract of D. mucronata were intraperitoneally administered to the mice 30 min before analgesic test. The anti-nocicepti ...
- DOI:
- 10.1016/j.apjtb.2015.12.004
- https://doi.org/10.1016/j.apjtb.2015.12.004
- Author:
- Beatriz P Monteiro; Mary P Klinck; Maxim Moreau; Martin Guillot; Paulo VM Steagall; Daniel K Edge; Jean‐Pierre Pelletier; Johanne Martel‐Pelletier; Dominique Gauvin; Jérôme RE del Castillo; Eric Troncy
- Source:
- Veterinary anaesthesia and analgesia 2016 v.43 no.6 pp. 643-651
- ISSN:
- 1467-2987
- Subject:
- adverse effects; analgesics; body weight; cats; data analysis; elderly; gastrointestinal system; hypersensitivity; meloxicam; osteoarthritis; pain; placebos; statistical analysis; toxicity
- Abstract:
- ... To evaluate the analgesic efficacy of meloxicam oral transmucosal spray (OTMS) alone and with tramadol in cats with osteoarthritis (OA).Randomized, blinded study.Fifteen geriatric cats weighing 4.5 ± 1.0 kg.Healthy cats with OA were randomly administered a placebo (every 12 hours orally) and meloxicam OTMS (approximately 0.05 mg kg−1 every 24 hours) (group M, n = 7), or tramadol (3 mg kg−1 every 1 ...
- DOI:
- 10.1111/vaa.12360
- https://doi.org/10.1111/vaa.12360
- Author:
- Feng Liu; Yangzhen Li; Min Du; Changwei Shao; Songlin Chen
- Source:
- Chinese journal of oceanology and limnology 2016 v.34 no.1 pp. 163-169
- ISSN:
- 0254-4059
- Subject:
- Cynoglossus semilaevis; aquaculture; body weight; breeding stock; breeding value; correlation; females; genetic correlation; genotype; heritability; males; parents; phenotype; prediction; progeny; statistical models; variance
- Abstract:
- ... Phenotypic and genetic parameters for growth-related traits in the half-smooth tongue sole, Cynoglossus semilaevis, were estimated in 22 full-sib families produced by normal and neo-male breeding stocks. As phenotypic males with female genotypes, neo-males are harmful in C. semilaevis aquaculture because they reduce overall production. The present study evaluated the difference in the growth-relat ...
- DOI:
- 10.1007/s00343-016-5044-y
- https://doi.org/10.1007/s00343-016-5044-y
- Author:
- Nathalie Grova; Emilie M. Hardy; Pauline Meyer; Brice M. R. Appenzeller
- Source:
- Analytical and bioanalytical chemistry 2016 v.408 no.8 pp. 1997-2008
- ISSN:
- 1618-2642
- Subject:
- DNA; benzo(a)pyrene; biomarkers; body weight; gas chromatography; humans; hydrolysis; ionization; isomers; metabolites; oils; oral administration; polycyclic aromatic hydrocarbons; rats; tandem mass spectrometry
- Abstract:
- ... A first gas chromatography–tandem mass spectrometry (GC–MS/MS) method was designed for analysis of four tetrahydroxylated benzo[a]pyrene metabolites (benzo[a]pyrene-r-7,t-8,t-9,c-10-tetrahydrotetrol, benzo[a]pyrene-r-7,t-8,t-9,t-10-tetrahydrotetrol, benzo[a]pyrene-r-7,t-8,c-9,c-10-tetrahydrotetrol, and benzo[a]pyrene-r-7,t-8,c-9,t-10-tetrahydrotetrol) in hair. Hair powder extract was submitted to ...
- DOI:
- 10.1007/s00216-016-9338-x
- https://doi.org/10.1007/s00216-016-9338-x
- Author:
- S. Achanta; A. Sewell; J. W. Ritchey; K. Broaddus; D. W. A. Bourne; C. R. Clarke; L. K. Maxwell
- Source:
- Journal of veterinary pharmacology and therapeutics 2016 v.39 no.3 pp. 224-236
- ISSN:
- 0140-7783
- Subject:
- adults; algorithms; allometry; blood flow; body weight; cisplatin; cytotoxicity; dogs; equations; glomerular filtration rate; heart; juveniles; kidneys; males; models; neoplasms; patients; pharmacokinetics
- Abstract:
- ... Cisplatin is a platinum‐containing cytotoxic drug indicated for the treatment of solid tumors in veterinary and human patients. Several of the algorithms used to standardize the doses of cytotoxic drugs utilize allometry, or the nonproportional relationships between anatomical and physiological variables, but the underlying basis for these relationships is poorly understood. The objective of this ...
- DOI:
- 10.1111/jvp.12266
- https://doi.org/10.1111/jvp.12266
- Author:
- Xiaoqian Ji; Changzheng Li; Yitao Ou; Ning Li; Kai Yuan; Guizhi Yang; Xiaoyan Chen; Zhicheng Yang; Bing Liu; Wai W. Cheung; Lijing Wang; Ren Huang; Tian Lan
- Source:
- Molecular and Cellular Endocrinology 2016 v.437 pp. 268-279
- ISSN:
- 0303-7207
- Subject:
- albuminuria; animal disease models; blood glucose; blood serum; body weight; cell proliferation; creatinine; cytokines; diabetic nephropathy; extracellular matrix; fasting; fibronectins; fibrosis; high fat diet; hypertrophy; inflammation; intraperitoneal injection; kidneys; mice; oxidative stress; signal transduction; streptozotocin; triacylglycerols; urea nitrogen
- Abstract:
- ... Diabetic nephropathy (DN) is characterized by proliferation of mesangial cells, mesangial hypertrophy and extracellular matrix (ECM) accumulation. Our recent study found that andrographolide inhibited high glucose-induced mesangial cell proliferation and fibronectin expression through inhibition of AP-1 pathway. However, whether andrographolide has reno-protective roles in DN has not been fully el ...
- DOI:
- 10.1016/j.mce.2016.06.029
- https://doi.org/10.1016/j.mce.2016.06.029
59. Animal Performance and Pasture Characteristics on Cool-Season Annual Grass Mixtures in North Florida
- Author:
- José C.B. Dubeux; Nicolas DiLorenzo; Ann Blount; Cheryl Mackowiak; Erick R.S. Santos; Hiran M.S. Silva; Martin Ruiz-Moreno; Tessa Schulmeister
- Source:
- Crop science 2016 v.56 no.5 pp. 2841-2852
- ISSN:
- 0011-183X
- Subject:
- Avena sativa; Lolium multiflorum; Secale cereale; annuals; average daily gain; blood; body weight; botanical composition; cold season; forage; grasses; grazing; grazing management; livestock; oats; organic matter; pastures; rye; stocking rate; triticale; urea nitrogen; Florida
- Abstract:
- ... Cool-season forage mixtures are an option for extending the length of the grazing season. Small grains have a different growth distribution than annual ryegrass and may increase livestock gain per area. This 2-yr grazing study tested three small grain–annual ryegrass mixtures: (i) cereal rye (Secale cereale L. ‘FL401’)–annual ryegrass (Lolium multiflorum Lam. ‘Prine’); (ii) oat (Avena sativa L. ‘H ...
- DOI:
- 10.2135/cropsci2016.03.0141
- https://doi.org/10.2135/cropsci2016.03.0141
- Author:
- Misa Tominaga; Yuka Momonaka; Chihiro Yokose; Miki Tadaishi; Makoto Shimizu; Takumi Yamane; Yuichi Oishi; Kazuo Kobayashi-Hattori
- Source:
- Toxicon 2016 v.118 pp. 54-60
- ISSN:
- 0041-0101
- Subject:
- anorexia; body weight; cholecystokinin; deoxynivalenol; females; food intake; hypothalamus; interleukin-1beta; interleukin-6; intestines; messenger RNA; mice; pro-opiomelanocortin; receptor protein-tyrosine kinase; transcription factor NF-kappa B; tumor necrosis factor-alpha; weight gain
- Abstract:
- ... Although deoxynivalenol (DON) suppresses food intake and subsequent weight gain, its contribution to anorexia mechanisms has not been fully clarified. Thus, we investigated the anorexic actions of DON in the hypothalamus and intestine, both organs related to appetite. When female B6C3F1 mice were orally exposed to different doses of DON, a drastic anorexic action was observed at a dose of 12.5 mg/ ...
- DOI:
- 10.1016/j.toxicon.2016.04.036
- https://doi.org/10.1016/j.toxicon.2016.04.036
- Author:
- Biji Cyriac; K. Eswaran
- Source:
- Journal of applied phycology 2016 v.28 no.4 pp. 2507-2513
- ISSN:
- 0921-8971
- Subject:
- Kappaphycus alvarezii; alloxan; alpha-glucosidase; animal disease models; bioactive compounds; blood glucose; blood lipids; body weight; cost effectiveness; diabetes; food intake; glycemic effect; glycosylation; health foods; hemoglobin; high density lipoprotein cholesterol; hypoglycemic agents; insulin; low density lipoprotein; macroalgae; oral administration; patients; phospholipids; rats; triacylglycerols
- Abstract:
- ... The intake of food and control of blood glucose levels are very important in diabetic patients. α-Glucosidase inhibitors are a cost-effective means to prevent the progression of diabetes. To find a natural inhibitor from seaweed with anti-hyperglycemic effects, methanolic extract of a red seaweed, Kappaphycus alvarezii (Doty) Doty ex P. Silva, which contains complex mixtures of various types of bi ...
- DOI:
- 10.1007/s10811-015-0762-7
- https://doi.org/10.1007/s10811-015-0762-7
- Author:
- Mustafa Erboga; Mehmet Kanter; Cevat Aktas; Yeliz Bozdemir Donmez; Zeynep Fidanol Erboga; Emel Aktas; Ahmet Gurel
- Source:
- Biological trace element research 2016 v.171 no.1 pp. 176-184
- ISSN:
- 0163-4984
- Subject:
- blood serum; caffeic acid; humans; body weight; oxidative stress; lipid peroxidation; males; reactive oxygen species; cadmium; health hazards; tissues; intraperitoneal injection; testosterone; rats; testes; antioxidant activity; toxicity; apoptosis
- Abstract:
- ... Cadmium (Cd) is a serious environmental and occupational contaminant and may represent a serious health hazard to humans and other animals. Cd is reported to induce the generation of reactive oxygen species, and induces testicular damage in many species of animals. The goal of our study was to examine the anti-apoptotic and anti-oxidant effects of caffeic acid phenethyl ester (CAPE) on Cd-induced ...
- DOI:
- 10.1007/s12011-015-0509-y
- https://doi.org/10.1007/s12011-015-0509-y
- Author:
- Hye Jeong Yang; Min Jung Kim; Dae Young Kwon; Da Sol Kim; Young Hyun Lee; Ji Eun Kim; Sunmin Park
- Source:
- Nutrients 2016 v.8 no.3 pp. -
- ISSN:
- 2072-6643
- Subject:
- Gastrodia elata; apoptosis; blood serum; body weight; brain; dextrins; dietary supplements; glucose; glucose clamp technique; glycemic effect; high fat diet; hyperinsulinemia; insulin; insulin resistance; insulin secretion; islets of Langerhans; metabolism; noninsulin-dependent diabetes mellitus; rats; therapeutics
- Abstract:
- ... The brain is an important modulator of glucose metabolism, and is known to respond Gastrodia elata Blume water extract (GEB). Therefore, we examined whether long-term administration of GEB has hypoglycemic activity, and its action mechanism was explored in partially-pancreatectomized rats that exhibit similar characteristics as Asian type 2 diabetes, non-obese insulin-insufficient diabetes. The ra ...
- DOI:
- 10.3390/nu8030161
- PubMed:
- 26978400
- PubMed Central:
- PMC4808889
- https://doi.org/10.3390/nu8030161
64. Anti-Fatigue Effects of Small Molecule Oligopeptides Isolated from Panax ginseng C. A. Meyer in Mice
- Author:
- Lei Bao; Xiaxia Cai; Junbo Wang; Yuan Zhang; Bin Sun; Yong Li
- Source:
- Nutrients 2016 v.8 no.12 pp. -
- ISSN:
- 2072-6643
- Subject:
- Panax ginseng; antioxidant enzymes; bioactive properties; biogenesis; biomarkers; blood serum; body weight; exercise; gene expression; ginsenosides; glycogen; lactate dehydrogenase; lactic acid; mice; mitochondria; mitochondrial DNA; oligopeptides; oxidative stress; physical fitness; skeletal muscle; swimming; urea nitrogen; Asia
- Abstract:
- ... Panax ginseng C. A. Meyer (ginseng) is an edible and medicinal Chinese herb, which is often used in Asian countries for physical fitness. Ginseng is reported to have a wide range of biological activity and pharmaceutical properties. There were more studies on ginsenosides and polysaccharides, but fewer studies on ginseng oligopeptides (GOP), which are small molecule oligopeptides isolated from gin ...
- DOI:
- 10.3390/nu8120807
- PubMed:
- 27983571
- PubMed Central:
- PMC5188462
- https://doi.org/10.3390/nu8120807
- Author:
- Lee Seong-Ho; Clark Ruth
- Source:
- Journal of food chemistry & nanotechnology 2016 Volume2 Issue4 pp. 162-167
- ISSN:
- 2471-4291
- Subject:
- Western blotting; antineoplastic activity; antineoplastic agents; body weight; capsaicin; cell culture; colorectal neoplasms; cyclins; dose response; food chemistry; humans; intestines; mice; neoplasm cells; phosphorylation; proteasome endopeptidase complex; threonine; ubiquitination
- Abstract:
- ... Colon cancer is one of most common malignancies in the world. Capsaicin is a major component of chili peppers and has been shown to possess anti-cancer activity against various types of cancers. There is currently a limited number of preclinical studies that test the anti-cancer effects of capsaicin in colon cancer. The first objective of the present study is to investigate whether capsaicin influ ...
- DOI:
- 10.17756/jfcn.2016-025
- https://doi.org/10.17756/jfcn.2016-025
- Author:
- Xin-Hua Nabi; Chun-Yan Ma; Tabusi Manaer; Mulalibieke Heizati; Baheti Wulazibieke; Latipa Aierken
- Source:
- BMC complementary and alternative medicine 2016 v.16 no.1 pp. 309
- ISSN:
- 1472-6882
- Subject:
- C-reactive protein; Lactobacillus brevis; Lactobacillus casei; Lactobacillus helveticus; Lactobacillus kefiri; Lactobacillus plantarum; Lactococcus; Saccharomyces; alternative medicine; aorta; atherosclerosis; blood lipids; blood serum; body weight; cell adhesion; cheese whey; diet; drugs; endothelium; fibroblasts; flavor; foam cells; histology; intercellular adhesion molecule-1; lactic acid bacteria; lipid composition; lipid metabolism; medicine; nucleotide sequences; probiotics; protective effect; rabbits; yeasts
- Abstract:
- ... BACKGROUND: Traditional fermented cheese whey (TFCW), containing probiotics, has been used both as a dairy food with ethnic flavor and a medicine for cardiovascular disease, especially regulating blood lipid among Kazakh. We therefore investigated anti-atherosclerotic effects of TFCW in atherosclerotic rabbits and identified lactic acid bacteria (LAB) and yeasts in TFCW. METHODS: Atherosclerotic r ...
- DOI:
- 10.1186/s12906-016-1285-8
- PubMed:
- 27553960
- PubMed Central:
- PMC4995647
- https://doi.org/10.1186/s12906-016-1285-8
- Author:
- Huikun Duan; Baicheng Ma; Xiaofeng Ma; Haisong Wang; Zaizhong Ni; Bin Wang; Xiaodan Li; Pingzhe Jiang; Muhammad Umar; Minggang Li
- Source:
- International journal of biological macromolecules 2016 v.84 pp. 457-463
- ISSN:
- 0141-8130
- Subject:
- food intake; energy; blood serum; body weight; blood glucose; glycemic effect; gene expression; mice; genes; insulin; intraperitoneal injection; sodium chloride; diabetes; oral administration; glucose tolerance; animal disease models
- Abstract:
- ... In order to investigate the hypoglycemic effects and potential mechanism of recombinant irisin on diabetes, STZ-induced diabetic mice were established and treated with irisin. The results showed that daily water and food intake, and blood glucose significantly decreased after various concentrations of recombinant irisin treatment by intraperitoneal injection, of which 1.0mg/kg was the optimal dose ...
- DOI:
- 10.1016/j.ijbiomac.2015.12.049
- https://doi.org/10.1016/j.ijbiomac.2015.12.049
- Author:
- Aminu Mohammed; Neil Anthony Koorbanally; Md. Shahidul Islam
- Source:
- Journal of ethnopharmacology 2016 v.180 pp. 131-139
- ISSN:
- 0378-8741
- Subject:
- Xylopia aethiopica; acetone; blood glucose; blood lipids; blood serum; body weight; fructose; fruits; glucose tolerance; glycemic effect; glycogen; histopathology; insulin; insulin resistance; intraperitoneal injection; islets of Langerhans; liver; metformin; models; noninsulin-dependent diabetes mellitus; rats; streptozotocin; traditional medicine; Western Africa
- Abstract:
- ... In traditional medicine from West Africa, the fruit decoction of Xylopia aethiopica (Dunal) A. Rich. is widely used for the treatment of diabetes mellitus (DM) either alone or in combination with other plants. The present study is designed to investigate the anti-diabetic effects of X. aethiopica acetone fraction (XAAF) from fruit ethanolic extract in a type 2 diabetes (T2D) model of rats.T2D was ...
- DOI:
- 10.1016/j.jep.2016.01.009
- https://doi.org/10.1016/j.jep.2016.01.009
- Author:
- Mengmei Ma; Taihua Mu
- Source:
- Journal of functional foods 2016 v.25 pp. 186-196
- ISSN:
- 1756-4646
- Subject:
- animal disease models; blood glucose; body weight; colon; cumin; dietary fiber; glycemic effect; insulin; lipid metabolism; liver; males; metformin; noninsulin-dependent diabetes mellitus; rats; short chain fatty acids; streptozotocin
- Abstract:
- ... The effects of soluble dietary fibre (SDF) and insoluble dietary fibre (IDF) from deoiled cumin on low-dose streptozotocin and high glucose-fat-induced type 2 diabetes rats were examined. Male Wistar rats were divided into nine groups: control (non-diabetic, no SDF or IDF intake), model (diabetes only), metformin, high-dose SDF (5 g/kg body weight), middle-dose SDF (500 mg/kg body weight), low-dos ...
- DOI:
- 10.1016/j.jff.2016.05.011
- https://doi.org/10.1016/j.jff.2016.05.011
- Author:
- Yiyi Hu; Aihua Mao; Zhengyu Yu; Kongwang He
- Source:
- Microbial pathogenesis 2016 v.99 pp. 51-55
- ISSN:
- 0882-4010
- Subject:
- anti-inflammatory activity; body temperature; body weight; endotoxins; herbal medicines; inflammation; ingredients; mice; sinomenine; weight loss
- Abstract:
- ... The aim of the research was to investigate the anti-endotoxin and anti-inflammatory effects of sinomenine, fangchinoline, stachydrine, chuanxionggzine, oxymartrine, and evodiamine alkaloids commonly found in Chinese herbal medicines. In an endotoxin (LPS) control group, each mouse was challenged with 1 mg LPS/kg by intraperitoneal (IP) injection. In high-, middle- and low-dose alkaloid groups, mic ...
- DOI:
- 10.1016/j.micpath.2016.08.006
- https://doi.org/10.1016/j.micpath.2016.08.006
- Author:
- Edgar E. Caamal-Fuentes; Manlio Graniel-Sabido; Gonzalo J. Mena-Rejón; Rosa E. Moo-Puc
- Source:
- Journal of ethnopharmacology 2016 v.193 pp. 604-606
- ISSN:
- 0378-8741
- Subject:
- Cassia; Giardia lamblia; active ingredients; acute toxicity; adults; bark; body weight; diarrhea; growth retardation; high performance liquid chromatography; methanol; mice; models; mortality; necropsy; oral administration; rats; traditional medicine; trophozoites; Mexico
- Abstract:
- ... Senna racemosa (Mill.) H.S. Irwin & Barneby (syn. Cassia racemosa Mill.) is a plant used in traditional Mayamedicinal practices to treat diarrhea. A methanol extract of S. racemosa bark has been shown to have in vitro activity against Giardia intestinalis. No studies of its efficacy and toxicity in in vivo models have been done. The present study objective was to analyze the activity of this metha ...
- DOI:
- 10.1016/j.jep.2016.09.055
- https://doi.org/10.1016/j.jep.2016.09.055
- Author:
- P. Ahmadi Pirshahid; C. Thisayakorn; T. Hemthanon; T. Suntorntanasat; C. Banchonglikitkul; J. Eiamwat; S. Sookwhan
- Source:
- Acta horticulturae 2016 v. no.1125 pp. 161-172
- ISSN:
- 0567-7572
- Subject:
- Cissus quadrangularis; acute toxicity; biomarkers; body weight; death; diclofenac; dietary exposure; drugs; edema; endothelium; ethanol; hemorrhage; histopathology; median effective concentration; medicinal plants; pain; patients; phenylephrine; poisoning; quality control; rats; subchronic toxicity; toxicity testing; traditional medicine
- Abstract:
- ... Cissus quadrangularis L. is a medicinal plant widely used in Thai traditional medicine, especially to alleviate hemorrhoids. The aim of the present study was to investigate acute oral toxicity, anti-inflammatory and venoconstrictive effects of a whole plant standardized ethanol extract from C. quadrangularis in rats, followed by the evaluation of safety and efficacy of enteric film coated tablets ...
- DOI:
- 10.17660/ActaHortic.2016.1125.20
- https://doi.org/10.17660/ActaHortic.2016.1125.20
- Author:
- Mohd Fasih Ahmad; Syed Mahboob Ahmad; Raj K. Keservani; Anil K. Sharma
- Source:
- National Academy science letters 2016 v.39 no.6 pp. 421-425
- ISSN:
- 0250-541X
- Subject:
- Solanum tuberosum; anti-inflammatory activity; body weight; carrageenan; edema; formalin; histamine; ibuprofen; inflammation; lethal dose 50; males; models; mortality; potatoes; rats; tubers
- Abstract:
- ... The objective of present investigation was to evaluate the anti-inflammatory activity of tuber extracts of Solanum tuberosum in rats. Anti-inflammatory models like Carrageenan, Histamine and Formalin induced paw edema were used for evaluating anti-inflammatory activity. Ibuprofen was used as standard drug. The alcoholic extract as well as aqueous extract of tubers of S. tuberosum subjected to LD₅₀ ...
- DOI:
- 10.1007/s40009-016-0466-9
- https://doi.org/10.1007/s40009-016-0466-9
- Author:
- Ana L.A. Lima; Adriano F. Alves; Aline L. Xavier; Talissa Mozzini-Monteiro; Theresa R.R. Oliveira; Fagner C. Leite; Wemerson N. Matias; Marianna V.S.C. Branco; Maria F.V. Souza; Marcia R. Piuvezam
- Source:
- Revista Brasileira de Farmacognosia 2016 v.26 no.2 pp. 225-232
- ISSN:
- 0102-695X
- Subject:
- Malvaceae; acetic acid; acute toxicity; aerial parts; anti-inflammatory activity; body weight; carrageenan; cell movement; cytotoxicity; edema; females; inflammation; interleukin-1beta; interleukin-6; macrophages; males; mice; models; mortality; nitric oxide; peritonitis; toxicity testing; tumor necrosis factor-alpha
- Abstract:
- ... Hydroalcoholic extract of aerial parts of Herissantia tiubae (K. Schum.) Brizicky, Malvaceae, was evaluated in experimental models of inflammation and toxicity. For toxicity assays, male and female Swiss mice were orally treated with hydroalcoholic extract of H. tiubae (2000mg/kg) and analyzed by consumption of water and food, body weight, mortality and rates of major organ weights, as well as bio ...
- DOI:
- 10.1016/j.bjp.2015.11.001
- https://doi.org/10.1016/j.bjp.2015.11.001
- Author:
- Bo-Kyeong Kang; Min-Ji Kim; Koth-Bong-Woo-Ri Kim; Dong-Hyun Ahn
- Source:
- Food science and biotechnology 2016 v.25 no.3 pp. 847-854
- ISSN:
- 1226-7708
- Subject:
- Katsuwonus pelamis; anti-inflammatory activity; body weight; dose response; ears; edema; heart; histology; inducible nitric oxide synthase; interleukin-1beta; interleukin-6; lipopolysaccharides; mast cells; mice; mitogen-activated protein kinase; models; mortality; nitric oxide; prostaglandin synthase; transcription factor NF-kappa B; tumor necrosis factor-alpha
- Abstract:
- ... This study investigated the anti-inflammatory activity of the ethanolic extract (THEE) obtained from the heart of skipjack tuna using lipopolysaccharide (LPS)-induced RAW 264.7 cells. THEE markedly suppressed the production of nitric oxide (NO), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and IL-1β in a dose-dependent manner. In addition, THEE decreased the expression of inducible NO sy ...
- DOI:
- 10.1007/s10068-016-0140-5
- PubMed:
- 30263344
- PubMed Central:
- PMC6049154
- https://doi.org/10.1007/s10068-016-0140-5
- Author:
- Min-Gyung Kang; Hee Jae Lee; Jae-Young Cho; Kanghwa Kim; Soo Jin Yang; Doman Kim
- Source:
- Biochemical and biophysical research communications 2016 v.477 pp. 350-355
- ISSN:
- 0006-291X
- Subject:
- Toll-like receptor 4; adiponectin; alanine transaminase; anti-inflammatory activity; aspartate transaminase; blood glucose; blood serum; body weight; dextransucrase; energy content; food intake; functional foods; gene expression; glycemic control; homeostasis; inflammation; ingredients; insulin; insulin receptors; interleukin-6; liver function; males; mice; mutants; stomach; sucrose; transcription factor NF-kappa B; tumor necrosis factor-alpha
- Abstract:
- ... Oligosaccharide (OS) is used as a sugar replacement as well as an ingredient in functional foods because of its beneficial effects, mainly on reducing calorie content and promoting intestinal health. By contrast, the effects of OS on inflammation are less well investigated. The purpose of this study was to investigate the effects of sucrose-derived OS on glucose control and inflammation in high fa ...
- DOI:
- 10.1016/j.bbrc.2016.06.102
- https://doi.org/10.1016/j.bbrc.2016.06.102
- Author:
- Ramasamy Chandramohan; Leelavinothan Pari
- Source:
- Journal of functional foods 2016 v.27 pp. 17-28
- ISSN:
- 1756-4646
- Subject:
- C-reactive protein; animal disease models; anti-inflammatory activity; antioxidant activity; antioxidants; blood glucose; body weight; diabetes mellitus; immunohistochemistry; insulin; interleukin-6; lipid peroxidation; liver; olive oil; oral administration; pancreas; rats; streptozotocin; transcription factor NF-kappa B; tumor necrosis factor-alpha
- Abstract:
- ... The anti-inflammatory effect of tyrosol (4-(2-hydroxyethyl)), a phenolic compound in olive oil (20 mg/kg body weight), in streptozotocin (STZ)-induced diabetic rat was evaluated. Diabetic rats showed significant (P < 0.05) increase in plasma glucose and lipid peroxidation products and significant (P < 0.05) decrease in plasma insulin and enzymatic and non-enzymatic antioxidants in the liver and pa ...
- DOI:
- 10.1016/j.jff.2016.08.043
- https://doi.org/10.1016/j.jff.2016.08.043
- Author:
- Tao Wu; Zenghong Jiang; Jinjin Yin; Hairong Long; Xiaodong Zheng
- Source:
- International journal of food sciences and nutrition 2016 v.67 no.3 pp. 257-264
- ISSN:
- 1465-3478
- Subject:
- Vaccinium virgatum; adipocytes; anthocyanins; blood glucose; blueberries; body weight; epididymis; fatty acids; high fat diet; inflammation; interleukin-6; males
- Abstract:
- ... This study aimed to evaluate the anti-obesity effects of artificial planting blueberry (Vaccinium ashei) anthocyanin (BA) in high-fat diet-induced obese male C57BL/6 mice. BA at doses of 50, 100, and 200 mg/kg was supplemented in the daily food of obese C57BL/6 mice during an 8-week experiment. Our findings indicate that consumption of BA at high doses reduced body weight by 19.4%, whereas both lo ...
- DOI:
- 10.3109/09637486.2016.1146235
- https://doi.org/10.3109/09637486.2016.1146235
- Author:
- H. W. Shin; E. S. Jang; B. S. Moon; J. J. Lee; D. E. Lee; C. H. Lee; C. S. Shin
- Source:
- Journal of food science and technology 2016 v.53 no.2 pp. 1004-1013
- ISSN:
- 0022-1155
- Subject:
- rice; weight gain; diet; epididymis; liver; blood serum; bioactive properties; NADP-glucose-6-phosphate dehydrogenase; body weight; lipoprotein lipase; malic enzyme; capsaicin; adipose tissue; soybeans; koji; triacylglycerols; genistein; rats; fatty-acid synthase; fungi
- Abstract:
- ... The Korean traditional hot sauce gochujang has been reported to have biological activities. Different kinds of gochujang products were prepared based on combinations of a fungal rice koji with two kinds of bacterial soybean mejus. Diets that included gochujang products were fed to rats and anti-obesity effects were investigated. Gochujang products reduced body weight gains, epididymal fat weights, ...
- DOI:
- 10.1007/s13197-015-2162-z
- PubMed:
- 27162380
- PubMed Central:
- PMC4837739
- https://doi.org/10.1007/s13197-015-2162-z
- Author:
- Olivier Desrues; Miguel Peña-Espinoza; Tina V. A. Hansen; Heidi L. Enemark; Stig M. Thamsborg
- Source:
- Parasites & vectors 2016 v.9 no.1 pp. 329
- ISSN:
- 1756-3305
- Subject:
- Cooperia oncophora; Jersey; Onobrychis viciifolia; Ostertagia ostertagi; abomasum; adults; albumins; anthelmintics; antiparasitic properties; blood composition; body weight; calves; diet; digestibility; eggs; excretion; feed intake; foraging; hay; larvae; legumes; males; necropsy; parasites; pellets; pepsinogen; phosphorus; scanning electron microscopy; sieving; small ruminants; weight gain
- Abstract:
- ... BACKGROUND: Increasing anthelmintic-resistance in nematodes of ruminants emphasises the need for sustainable parasite control. Condensed tannin-containing legume forages such as sainfoin (Onobrychis viciifolia) have shown promising anthelmintic properties in small ruminants but this has never been explored in cattle. Therefore, our aim was to examine the efficacy of sainfoin against cattle nematod ...
- DOI:
- 10.1186/s13071-016-1617-z
- PubMed:
- 27283323
- PubMed Central:
- PMC4901493
- https://doi.org/10.1186/s13071-016-1617-z
- Author:
- Ememobong Gideon Asuquo; Chinweizu Ejikeme Udobi; Tsai-Ching Hsu
- Source:
- Cogent biology 2016 v.2 no.1 pp. 1219248
- ISSN:
- 2331-2025
- Subject:
- Musa paradisiaca; acute toxicity; albino; antibacterial properties; body weight; cell viability; ethanol; flavonoids; leaves; minimum inhibitory concentration; secondary metabolites; toxicity testing
- Abstract:
- ... The ethanol extract of the leaf of Musa paradisiaca and its aqueous fraction were investigated for antibacterial potentials against Gram-positive and Gram-negative organisms of clinical importance. Phytochemical screenings showed the presence of secondary metabolites namely tannin, flavonoids, alkaloids among others. When the extracts were subjected to susceptibility test, results showed that whil ...
- DOI:
- 10.1080/23312025.2016.1219248
- https://doi.org/10.1080/23312025.2016.1219248
- Author:
- F Ling; Z‐Q Wu; C Jiang; L Liu; G‐X Wang
- Source:
- Journal of fish diseases 2016 v.39 no.8 pp. 993-1000
- ISSN:
- 0140-7775
- Subject:
- Aeromonas hydrophila; Cyprinus carpio; antibacterial properties; antiparasitic properties; body weight; fish; fish culture; half life; high performance liquid chromatography; industry; intraperitoneal injection; kidneys; liver; microbial load; muscles; pathogens; pharmacokinetics; sanguinarine; spleen
- Abstract:
- ... Sanguinarine (SA), with antimicrobial and antiparasitic activities against fish pathogens, exhibits great potential commercial use in aquaculture. However, little information on pharmacokinetics of SA restricts further application in aquaculture. In this study, pharmacokinetics of SA in common carp (Cyprinus carpio) following a single intraperitoneal administration [10 mg kg⁻¹ BW (body weight)] wa ...
- DOI:
- 10.1111/jfd.12433
- https://doi.org/10.1111/jfd.12433
- Author:
- Serena Santolamazza-Carbone; Tamara Sotelo; Pablo Velasco; María Elena Cartea
- Source:
- Journal of pest science 2016 v.89 no.1 pp. 195-206
- ISSN:
- 1612-4758
- Subject:
- Brassica oleracea var. sabellica; Mamestra brassicae; Pieris rapae; antibiosis; antibiotics; body weight; genotype; glucobrassicin; glucoiberin; insect pests; larvae; larval development; leaves; mature plants; mortality; pupae; sinigrin; toxicity
- Abstract:
- ... Glucosinolates may deter generalist insect feeding as their toxicity causes fitness damage, whereas insects specialized in brassicaceous plants may circumvent the toxic effect. By using no-choice leaf tests, we investigated whether larval development time, body weight, mortality and feeding rate of the generalist Mamestra brassicae (Lepidoptera, Noctuidae) and the specialist Pieris rapae (Lepidopt ...
- DOI:
- 10.1007/s10340-015-0658-y
- https://doi.org/10.1007/s10340-015-0658-y
84. Anticancer effects of saponin and saponin–phospholipid complex of Panax notoginseng grown in Vietnam
- Author:
- Thu Dang Kim; Hai Nguyen Thanh; Duong Nguyen Thuy; Loi Vu Duc; Thu Vu Thi; Hung Vu Manh; Patcharee Boonsiri; Tung Bui Thanh
- Source:
- Asian Pacific Journal of Tropical Biomedicine 2016 v.6 pp. 795-800
- ISSN:
- 2221-1691
- Subject:
- Panax notoginseng; anthracenes; antineoplastic activity; antioxidant activity; body weight; breast neoplasms; breasts; carcinogenesis; catalase; cytotoxicity; enzyme activity; glutathione peroxidase; human diseases; in vivo studies; inhibitory concentration 50; lipid peroxidation; lung neoplasms; neoplasm cells; paclitaxel; phospholipids; saponins; superoxide dismutase; Vietnam
- Abstract:
- ... To evaluate the antitumor activity both in vitro and in vivo of saponin–phospholipid complex of Panax notoginseng.The in vitro cytotoxic effect of saponins extract and saponin–phospholipid complex against human lung cancer NCI-H460 and breast cancer cell lines BT474 was examined using MTS assay. For in vivo evaluation of antitumor potential, saponin and saponin–phospholipid complex were administer ...
- DOI:
- 10.1016/j.apjtb.2016.04.013
- https://doi.org/10.1016/j.apjtb.2016.04.013
- Author:
- Charatda Punvittayagul; Paweena Sankam; Sirinya Taya; Rawiwan Wongpoomchai
- Source:
- Nutrition and cancer 2016 v.68 no.4 pp. 646-653
- ISSN:
- 1532-7914
- Subject:
- Oryza sativa; Salmonella; acute toxicity; body weight; carcinogenicity; chemoprevention; diethylnitrosamine; glutathione; hepatocytes; liver; methanol; mutation; oral administration; rats; rice; Thailand
- Abstract:
- ... Oryza sativa L. var. indica cv. Kum Doi Saket is a pigmented rice variety grown in northern Thailand. Our previous study found that the methanol extract of purple rice seed had the highest level of antimutagenicity in a Salmonella mutation assay. The present study was designed to evaluate its in vivo anticlastogenic and anticarcinogenic potentials. The purple rice extract had no acute toxicity on ...
- DOI:
- 10.1080/01635581.2016.1158289
- https://doi.org/10.1080/01635581.2016.1158289
- Author:
- Hasan Habibi; Sobhan Firouzi; Hasan Nili; Mostafa Razavi; Seyedeh Leili Asadi; Sajad Daneshi
- Source:
- Journal of parasitic diseases 2016 v.40 no.2 pp. 401-407
- ISSN:
- 0971-7196
- Subject:
- Artemisia absinthium; Biarum; Cichorium intybus; Dorema; Eimeria tenella; Prangos; blood; body weight; broiler chickens; chicks; coccidiosis; diarrhea; diclazuril; drug resistance; drugs; feces; feed additives; feed conversion; growth performance; histopathology; in vivo studies; oocysts; survival rate
- Abstract:
- ... Safe alternative anticoccidial drug to chemical feed additives are herbal extracts, because they don’t results to tissue residue and drug resistance. In order to evaluate the effects of herbal extracts to control avian coccidiosis, 180 one-day-old broiler chickens were randomly divided into nine equal groups, as follows: (1) Biarum bovei (2) Nectaroscordum tripedale(3) Dorema aucheri (4) Cichorium ...
- DOI:
- 10.1007/s12639-014-0517-4
- PubMed:
- 27413312
- PubMed Central:
- PMC4927499
- https://doi.org/10.1007/s12639-014-0517-4
- Author:
- Agustín Pérez-Fonseca; Yazmin Alcala-Canto; Abdelfattah Z.M. Salem; Aldo B. Alberti-Navarro
- Source:
- Veterinary parasitology 2016 v.232 pp. 58-65
- ISSN:
- 0304-4017
- Subject:
- Eimeria; antioxidant activity; blood serum; body weight; coccidiosis; coccidiostats; drugs; grapefruits; lambs; naringenin; nitric oxide; oocysts; oral administration; oxidative stress; pharmacokinetics; toltrazuril; weight gain
- Abstract:
- ... The current study aimed to determine the anti-Eimeria efficacy of an extract of grapefruit peels (GF) and commercial naringenin (NAR) in naturally-infected lambs, as well as the influence of these flavonoids on the oxidative status during ovine coccidiosis. Pharmacokinetic profiles were also determined. Extracts were administered per os to Eimeria naturally infected growing lambs during 90 consecu ...
- DOI:
- 10.1016/j.vetpar.2016.11.009
- https://doi.org/10.1016/j.vetpar.2016.11.009
- Author:
- Pan Xu; Ke Zhu Wang; Cong Lu; Li Ming Dong; Jun Le Zhai; Yong Hong Liao; Silafu Aibai; Yanyan Yang; Xin Min Liu
- Source:
- Journal of ethnopharmacology 2016 v.194 pp. 819-826
- ISSN:
- 0378-8741
- Subject:
- Hemerocallis; active ingredients; antidepressants; blood serum; body weight; cognition; corticosterone; enzyme-linked immunosorbent assay; frontal lobe; herbal medicines; hippocampus; malondialdehyde; models; neurotransmitters; oxidative stress; phenols; rats; serotonin; sucrose; tandem mass spectrometry; traditional medicine; ultra-performance liquid chromatography
- Abstract:
- ... Depression induce distressed emotional state and cognitive deficits simultaneously, which both should be improved in the treatment. Hemerocallis citrina Baroni (HC) is a traditional herbal medicine in Eastern-Asia areas and the total phenols extract of HC (HCPE) contains the main active ingredients. It has been reported that HC has the emotional improvement effect. But the cognitive effect of HC w ...
- DOI:
- 10.1016/j.jep.2016.09.023
- https://doi.org/10.1016/j.jep.2016.09.023
89. Antidepressant-like effects of Xiaochaihutang in a neuroendocrine mouse model of anxiety/depression
- Author:
- Kuo Zhang; Jingyu Yang; Fang Wang; Xing Pan; Jian Liu; Lijuan Wang; Guangyue Su; Jie Ma; Yingxu Dong; Zhili Xiong; Chunfu Wu
- Source:
- Journal of ethnopharmacology 2016 v.194 pp. 674-683
- ISSN:
- 0378-8741
- Subject:
- corticosterone; dexamethasone; oral administration; liquid chromatography; immunohistochemistry; neurogenesis; brain; swimming; anxiety; traditional medicine; tail suspension test; body weight; rats; cell proliferation; pathophysiology; antidepressants; weight gain; escape behavior; tandem mass spectrometry; animal models; China
- Abstract:
- ... Hyperactivity of hypothalamic-pituitary-adrenal (HPA) axis is often observed in the pathophysiology of depression. Antidepressant therapy can restore hippocampal neurogenesis to rescue the HPA axis regulation defects. Xiaochaihutang (XCHT), a famous Chinese herbal formula, has been used clinically in depressive disorders in China. Our previous studies have demonstrated XCHT improved depressive-lik ...
- DOI:
- 10.1016/j.jep.2016.10.028
- https://doi.org/10.1016/j.jep.2016.10.028
- Author:
- Yu-En Lin; Shih-Hang Lin; Wei-Cheng Chen; Chi-Tang Ho; Yi-Syuan Lai; Suraphan Panyod; Lee-Yan Sheen
- Source:
- Journal of ethnopharmacology 2016 v.187 pp. 57-65
- ISSN:
- 0378-8741
- Subject:
- Gastrodia elata; Western blotting; abnormal behavior; amine oxidase (flavin-containing); animal models; blood serum; body weight; corticosterone; dopamine; forced swimming test; herbal medicines; nervous system diseases; neurotransmitters; oral administration; protein synthesis; rats; serotonin; sucrose; traditional medicine; tyrosine 3-monooxygenase
- Abstract:
- ... Gastrodia elata Blume (GE) is a traditional herbal medicine belonging to the Orchidaceae family, and has been used to manage neurological disorders for centuries. We have previously reported that its water extract (WGE) could improve the depressive-like behaviours in the forced swimming test (FST), an animal model of depression.To investigate the antidepressant-like effects of WGE in rats exposed ...
- DOI:
- 10.1016/j.jep.2016.04.032
- https://doi.org/10.1016/j.jep.2016.04.032
- Author:
- Tafadzwa Taderera; Exnevia Gomo; Lameck Shoriwa Chagonda
- Source:
- Journal of Biologically Active Products from Nature 2016 v.6 no.4 pp. 315-322
- ISSN:
- 2231-1874
- Subject:
- Annona; alloxan; animal disease models; blood glucose; body weight; diabetes; enzyme-linked immunosorbent assay; food consumption; glibenclamide; glucose; glucose tolerance tests; glycemic effect; hyperglycemia; insulin; males; plant extracts; rats
- Abstract:
- ... The antidiabetic activity of an aqueous root extract of Annona stenophylla Engl. and Diels, (Annonaceae) (100 mg/kg b.wt) in non-diabetic control and alloxan-induced diabetic rats (Alloxan monohydrate, 120 mg/kg b.wt) was investigated after inducing hyperglycaemia (OGTT, glucose 3 g/kg b.wt) in fasted male Sprague dawley rats. The rats were randomised into groups (n=6) and underwent oral glucose t ...
- DOI:
- 10.1080/22311866.2016.1234412
- https://doi.org/10.1080/22311866.2016.1234412
- Author:
- Mi Huang; Ping Zhao; Mingrui Xiong; Qi Zhou; Sijian Zheng; Xinhua Ma; Chan Xu; Jing Yang; Xinzhou Yang; Tong-Cun Zhang
- Source:
- Journal of ethnopharmacology 2016 v.191 pp. 71-81
- ISSN:
- 0378-8741
- Subject:
- AMP-activated protein kinase; Oriental traditional medicine; Western blotting; acetyl-CoA carboxylase; alanine transaminase; aspartate transaminase; blood glucose; blood serum; body weight; cold; ethyl acetate; glucose; glucose tolerance; glucose tolerance tests; glucose transporters; glycemic effect; insulin; insulin resistance; insulin tolerance test; mice; noninsulin-dependent diabetes mellitus; phosphorylation; signal transduction; skeletal muscle; China
- Abstract:
- ... Bitter and cold traditional Chinese medicines (TCMs) have been long used to treat diabetes mellitus (DM) based on unique medical theory system since ancient China. As one of bitter and cold TCMs, the stromatas of Shiraia bambusicola have been used for the treatment of DM and exerted clinical effects to a certain extent. However, the corresponding active principles and antidiabetic mechanism of the ...
- DOI:
- 10.1016/j.jep.2016.06.018
- https://doi.org/10.1016/j.jep.2016.06.018
- Author:
- Yanyan Zhang; Fu Feng; Ting Chen; Zhongwen Li; Qingwu W. Shen
- Source:
- Journal of ethnopharmacology 2016 v.192 pp. 256-263
- ISSN:
- 0378-8741
- Subject:
- Forsythia suspensa; Oriental traditional medicine; acid phosphatase; alanine transaminase; alkaline phosphatase; alpha-amylase; animal disease models; aspartate transaminase; blood glucose; body weight; cholesterol; coenzyme A; creatinine; diabetes mellitus; ethyl acetate; gene expression; genes; glucokinase; glucose; glucose tolerance; glycemic effect; homeopathic drugs; hydroxymethylglutaryl-CoA reductases; in vivo studies; insulin secretion; liver; liver function; methanol; mice; oxidative stress; pancreas; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; solvents; streptozotocin; therapeutics; triacylglycerols
- Abstract:
- ... The fruit of Forsythia suspense (Thunb.) Vahl, a well-known Chinese Materia Medica, has been traditionally used in traditional Chinese medicine for the treatment of diabetes and some other diseases, but the rational for the usage of this plant is unclear. The aim of this study was to investigate the therapeutic effect and potential mechanism of the fruit of F. suspensa using streptozotocin (STZ)-i ...
- DOI:
- 10.1016/j.jep.2016.07.002
- https://doi.org/10.1016/j.jep.2016.07.002
94. Antidiabetic and antioxidant activities of seed extract from Leucaena leucocephala (Lam.) de Wit
- Author:
- Pichaya Chowtivannakul; Buavaroon Srichaikul; Chusri Talubmook
- Source:
- Agriculture and natural resources 2016 v.50 no.5 pp. 357-361
- ISSN:
- 2452-316X
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Leucaena leucocephala; acute toxicity; albumins; alkaline phosphatase; animal disease models; antioxidant activity; ascorbic acid; blood glucose; blood serum; body weight; contraception; diabetes; digestive system diseases; erythrocytes; free radicals; glycemic effect; insulin; mortality; natural resources; oral administration; protein content; rats; renal function; seed extracts; spectrophotometers
- Abstract:
- ... Leucaena leucocephala (Lam.) de Wit has been used for various purposes such as treatment of stomach diseases, facilitation of abortion, contraception and the treatment of diabetes. Scientific information about this plant is limited. Therefore, this study investigated the antidiabetic and antioxidant activities and also the toxicity of seed extract from L. leucocephala (LLSE). Antidiabetic activity ...
- DOI:
- 10.1016/j.anres.2016.06.007
- https://doi.org/10.1016/j.anres.2016.06.007
- Author:
- Rumyana Simeonova; Vessela Vitcheva; Ilina Krasteva; Petranka Zdraveva; Spiro Konstantinov; Iliana Ionkova
- Source:
- Phytomedicine 2016 v.23 no.5 pp. 483-490
- ISSN:
- 0944-7113
- Subject:
- Gypsophila; aniline; animal disease models; antihypertensive effect; antioxidant activity; blood glucose; blood pressure; body weight; cytochrome P-450; diabetes; enzyme activity; glutathione; glutathione peroxidase; glutathione transferase; glutathione-disulfide reductase; hypertension; liver; malondialdehyde; oxidative stress; rats; risk; streptozotocin
- Abstract:
- ... Diabetes and hypertension are diseases that often coexist, which increases the risk of chronic organ damages and cardiovascular complications.To evaluate the effects of saponarin, isolated from Gypsophila trichotoma Wend, on blood pressure, glycemia, body weight, and liver biochemical parameters related to oxidative stress in diabetic normotensive Wistar Kyoto rats (NTR) and spontaneously hyperten ...
- DOI:
- 10.1016/j.phymed.2016.02.024
- https://doi.org/10.1016/j.phymed.2016.02.024
- Author:
- Jonathan Emeka Emordi; Esther Oluwatoyin Agbaje; Ibrahim Adekunle Oreagba; Osede Ignis Iribhogbe
- Source:
- BMC complementary and alternative medicine 2016 v.16 no.1 pp. 468
- ISSN:
- 1472-6882
- Subject:
- Acacia; Uvaria; albino; alternative medicine; animal disease models; blood glucose; body weight; cardiovascular diseases; cholesterol; developing countries; diabetes mellitus; etiology; glucose; hyperglycemia; insulin; insulin secretion; low density lipoprotein; pancreas; phytopharmaceuticals; plant products; rats; risk reduction; streptozotocin; weight loss
- Abstract:
- ... BACKGROUND: Diabetes mellitus is a metabolic disorder of multiple aetiology characterised by hyperglycemia resulting from defects in insulin secretion, insulin action or both. It is a global epidemic ravaging both developed and developing countries. The situation will worsen if nothing is done urgently. In fact, the need to identify natural products with antidiabetic potentials is of great importa ...
- DOI:
- 10.1186/s12906-016-1450-0
- PubMed:
- 27846886
- PubMed Central:
- PMC5111340
- https://doi.org/10.1186/s12906-016-1450-0
- Author:
- Rosa Martha Perez Gutierrez
- Source:
- Food science and biotechnology 2016 v.25 no.1 pp. 229-239
- ISSN:
- 1226-7708
- Subject:
- Piper auritum; alpha-amylase; alpha-glucosidase; animal disease models; beta-glucosidase; blood glucose; body weight; diabetic complications; enzyme activity; fractionation; glucose; high density lipoprotein cholesterol; insulin; insulin resistance; kidneys; leaves; lipid metabolism; lipid peroxidation; liver; low density lipoprotein; mass spectrometry; methanol; mice; nuclear magnetic resonance spectroscopy; oral administration; oxidative stress; pancreas; triacylglycerols; triterpenoid saponins
- Abstract:
- ... Bioactivity-guided fractionation of methanol extracts from leaves of Piper auritum produced four triterpenoid saponin compounds 1-4. Structures were established based on interpretation of mass spectrometry (MS), nuclear magnetic resonance (NMR) data. 21-(p-methoxycinnamoyl)-olean-12-ene-28oic cid-3-O-α-L-arabinopyranosyl-(1→2)-β-D-glucopyranoside (1) and olean-12-ene-28 methyl ester-3-O-α-L-arabin ...
- DOI:
- 10.1007/s10068-016-0034-6
- PubMed:
- 30263262
- PubMed Central:
- PMC6049373
- https://doi.org/10.1007/s10068-016-0034-6
- Author:
- Jian-mei Lu; Yan-fang Wang; Hong-li Yan; Pei Lin; Wen Gu; Jie Yu
- Source:
- Journal of ethnopharmacology 2016 v.179 pp. 291-300
- ISSN:
- 0378-8741
- Subject:
- Polygonatum; adenosine monophosphate; adipose tissue; adjuvants; animal disease models; blood glucose; blood serum; body weight; food intake; gene expression; glucokinase; glucose; glucose transporters; glucose-6-phosphatase; glycemic effect; glycogenesis; hyperglycemia; hyperlipidemia; insulin; insulin resistance; lipids; liver; metabolic syndrome; noninsulin-dependent diabetes mellitus; protein kinases; rats; saponins; signal transduction; skeletal muscle; streptozotocin; therapeutics; traditional medicine
- Abstract:
- ... Polygonatum kingianum has been used in the prevention and treatment of diabetes, hyperlipidemia and related metabolic syndrome in Asian counties for centuries. In this study, the blood glucose regulation activity and mechanism of total saponins from P. kingianum (TSPK) were investigated in streptozotocin (STZ)-induced diabetic rats in this research.TSPK (0.025g/kg and 0.1mg/kg) was administrated b ...
- DOI:
- 10.1016/j.jep.2015.12.057
- https://doi.org/10.1016/j.jep.2015.12.057
- Author:
- Diptirani Rath; Durga Madhab Kar; Sandeep Kumar Panigrahi; Laxmidhar Maharana
- Source:
- Journal of ethnopharmacology 2016 v.192 pp. 442-449
- ISSN:
- 0378-8741
- Subject:
- Cuscuta reflexa; aerial parts; animal disease models; blood glucose; body weight; diabetes mellitus; glucose; glycemic effect; histopathology; lipid composition; long term effects; metformin; methanol; oral administration; rats; solvents; streptozotocin; traditional medicine; tribal peoples; India
- Abstract:
- ... Cuscuta reflexa Roxb. (Convolvulaceae) is traditionally used to treat diabetes mellitus by tribal people of north-east India and Bangladesh.To evaluate the anti-diabetic effects of methanol and aqueous extracts of the aerial parts of Cuscuta reflexa Roxb. in normal, glucose loaded and Streptozotocin (STZ) induced diabetic rats.The methanol (MECR) and aqueous (AECR) extracts (200 and 400mg/kg body ...
- DOI:
- 10.1016/j.jep.2016.09.026
- https://doi.org/10.1016/j.jep.2016.09.026
- Author:
- A.O. Sulyman; J.O. Akolade; S.A. Sabiu; R.A. Aladodo; H.F. Muritala
- Source:
- Journal of ethnopharmacology 2016 v.182 pp. 122-128
- ISSN:
- 0378-8741
- Subject:
- Aristolochia; alkaloids; alpha-amylase; animal disease models; biomarkers; blood glucose; body weight; chemical composition; diabetes; ethanol; flavonoids; gas chromatography-mass spectrometry; glucose 6-phosphate; glucose tolerance tests; glycemic effect; glycogen; hyperglycemia; liver; oral administration; phenols; quantitative analysis; rats; roots; saponins; streptozotocin; tannins; traditional medicine; Nigeria
- Abstract:
- ... Oral administration of alcoholic decoctions of Aristolochia ringens is used extensively by Traditional Medicine Practitioners (TMP) of Yoruba heritage in South west, Nigeria for the management of diabetes and its associated complications.To assess the potentials of root ethanolic extract of Aristolochia ringens V. (REAR) in the management of diabetes using chemical induced experimental animal mode ...
- DOI:
- 10.1016/j.jep.2016.02.002
- https://doi.org/10.1016/j.jep.2016.02.002