U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Publication year rev 7984-2016 Remove constraint Publication year rev: 7984-2016 Subject term bone density Remove constraint Subject term: bone density
Start Over

Search

155  Search Results

« Previous | 1 - 50 of 155 |
Number of results to display per page

Search Results

1. A method of determining bending properties of poultry long bones using beam analysis and micro-CT data

Author:
Patrick E. Vaughan; Michael W. Orth; Roger C. Haut; Darrin M. Karcher
Source:
Poultry science 2016 v.95 no.1 pp. 207-212
ISSN:
0032-5791
Subject:
aviaries; biomechanics; bone density; bone health; equations; geometry; humans; micro-computed tomography
Abstract:
... While conventional mechanical testing has been regarded as a gold standard for the evaluation of bone heath in numerous studies, with recent advances in medical imaging, virtual methods of biomechanics are rapidly evolving in the human literature. The objective of the current study was to evaluate the feasibility of determining the elastic and failure properties of poultry long bones using establi ...
DOI:
10.3382/ps/pev345

2. A novel homozygous variant in SERPINH1 associated with a severe, lethal presentation of osteogenesis imperfecta with hydranencephaly

Author:
Charlotte Marshall; Jaime Lopez; Laura Crookes; Rebecca C Pollitt; Meena Balasubramanian
Source:
Gene 2016 v.595 no.1 pp. 49-52
ISSN:
0378-1119
Subject:
heat shock proteins; mechanism of action; mineralization; phenotype; collagen; bone formation; genetic disorders; bone density; children; patients; ribs; homozygosity; inheritance (genetics); exons; Mexico
Abstract:
... Osteogenesis imperfecta (OI) is a genetic disorder characterised by low bone mineral density resulting in fractures. 85–90% of patients with OI carry a variant in the type 1 collagen genes, COL1A1 and COL1A2, which follows an autosomal dominant pattern of inheritance. However, within the last two decades, there have been growing number of variants identified in genes that follow an autosomal reces ...
DOI:
10.1016/j.gene.2016.09.035

3. Alendronate-loaded hydroxyapatite-TiO₂ nanotubes for improved bone formation in osteoporotic rabbits

Author:
Xinkun Shen; Pingping Ma; Yan Hu; Gaoqiang Xu; Kui Xu; Weizhen Chen; Qichun Ran; Liangliang Dai; Yonglin Yu; Caiyun Mu; Kaiyong Cai
Source:
Journal of materials chemistry B 2016 v.4 no.8 pp. 1423-1436
ISSN:
2050-7518
Subject:
acid phosphatase; acidity; alkaline phosphatase; bone density; bone formation; calcium; gene expression; in vitro studies; in vivo studies; micro-computed tomography; mineralization; nanotubes; orthopedics; osteoblasts; osteoclasts; osteoporosis; protein synthesis; rabbits; staining
Abstract:
... Early mechanical fixation between an implant and native bone is critically important for successful orthopedic implantation, especially for hosts suffering osteoporosis with reduced bone mass. To endow a titanium-based implant with a desirable local anti-osteoporosis property for enhancing its early osseointegration, alendronate-loaded hydroxyapatite-TiO₂ nanotube (TNT-HA-Aln) substrates were fabr ...
DOI:
10.1039/c5tb01956g

4. Anthocyanin-Rich Blackcurrant Extract Attenuates Ovariectomy-Induced Bone Loss in Mice

Author:
Zheng Xi; Mun Sewhan; Lee Sang Gil; Vance Terrence M.; Hubert Patrice; Koo Sung I.; Lee Sun-Kyeong; Chun Ock K.
Source:
Journal of medicinal food 2016 v.19 no.4 pp. 390-397
ISSN:
1557-7600
Subject:
animal models; anthocyanins; anti-inflammatory activity; biomarkers; black currants; blood serum; bone density; bone formation; bone marrow cells; bone resorption; diet; dual-energy X-ray absorptiometry; femur; mice; micro-computed tomography; ovariectomy; postmenopause; resorption
Abstract:
... Although several animal and cell studies have indicated that blackcurrant anthocyanins exert antioxidative and anti-inflammatory properties, which could potentially improve bone mass, the effect of blackcurrant on bone health has not been reported yet. Thus, this study was aimed to evaluate the effect of blackcurrant anthocyanins on bone mass in an estrogen deficiency mouse model. Fourteen-week-ol ...
DOI:
10.1089/jmf.2015.0148

5. Association between dietary patterns and low bone mineral density among adults aged 50 years and above: findings from the North West Adelaide Health Study (NWAHS)

Author:
Yohannes Adama Melaku; Tiffany K. Gill; Robert Adams; Zumin Shi
Source:
British journal of nutrition 2016 v.116 no.8 pp. 1437-1446
ISSN:
1475-2662
Subject:
Western diets; adults; beers; bone density; cohort studies; data collection; dual-energy X-ray absorptiometry; eating habits; eggs; energy intake; factor analysis; fish; fruits; high fat dairy products; legumes; lifestyle; males; milk; potatoes; poultry; red meat; snacks; soft drinks; sugars; takeout foods; white bread; Australia
Abstract:
... Studies on the association between dietary patterns and bone mineral density (BMD) have reported inconsistent findings. Data from the North West Adelaide Health Study, a population-based cohort study undertaken in Australia, were used to assess this association among adults aged 50 years and above. In this specific study, 1182 adults (545 males, 45·9 %) had dietary data collected using a FFQ and a ...
DOI:
10.1017/S0007114516003366
PubMed:
27669817

6. Association between the methylenetetrahydrofolate reductase c.677C>T polymorphism and bone mineral density: an updated meta-analysis

Author:
Hong-Zhuo Li; Wei Wang; Yi-Ling Liu; Xiao-Feng He
Source:
Molecular genetics and genomics 2016 v.291 no.1 pp. 169-180
ISSN:
1617-4615
Subject:
Asians; Whites; bone density; cohort studies; femur; hips; lumbar spine; men; meta-analysis; methylenetetrahydrofolate reductase; models; postmenopause; women
Abstract:
... Many studies have reported an association between the methylenetetrahydrofolate reductase (MTHFR) c.677C>T polymorphism and reduced bone mineral density (BMD), but results have been inconsistent. We, therefore, performed a meta-analysis to further explore this association. Twenty-one studies, comprising 33,045 subjects, analyzed the association of MTHFR c.677C>T with femoral neck BMD. Significant ...
DOI:
10.1007/s00438-015-1101-z

7. Association of dietary and serum vitamin E with bone mineral density in middle-aged and elderly Chinese adults: a cross-sectional study

Author:
Wen-qi Shi; Jun Liu; Yi Cao; Ying-ying Zhu; Ke Guan; Yu-ming Chen
Source:
British journal of nutrition 2016 v.115 no.1 pp. 113-120
ISSN:
1475-2662
Subject:
Chinese people; alpha-tocopherol; blood serum; bone density; bone health; cross-sectional studies; dual-energy X-ray absorptiometry; elderly; femur; food intake; hips; interviews; lumbar spine; men; neck; questionnaires; reversed-phase high performance liquid chromatography; women; China
Abstract:
... Previous studies have suggested that vitamin E (VE) may affect bone health, but the findings have been inconclusive. We examined the relationship between VE status (in both diet and serum) and bone mineral density (BMD) among Chinese adults. This community-based study included 3203 adults (2178 women and 1025 men) aged 40–75 years from Guangzhou, People’s Republic of China. General and dietary int ...
DOI:
10.1017/S0007114515004134
PubMed:
26507315

8. Associations of breast-feeding patterns and introduction of solid foods with childhood bone mass: The Generation R Study

Author:
Edith H. van den Hooven; Mounira Gharsalli; Denise H. M. Heppe; Hein Raat; Albert Hofman; Oscar H. Franco; Fernando Rivadeneira; Vincent W. V. Jaddoe
Source:
British journal of nutrition 2016 v.115 no.6 pp. 1024-1032
ISSN:
1475-2662
Subject:
bone density; breast feeding; childhood; children; cohort studies; dual-energy X-ray absorptiometry; foods; mineral content; questionnaires; vitamin D
Abstract:
... Breast-feeding has been associated with later bone health, but results from previous studies are inconsistent. We examined the associations of breast-feeding patterns and timing of introduction of solids with bone mass at the age of 6 years in a prospective cohort study among 4919 children. We collected information about duration and exclusiveness of breast-feeding and timing of introduction of an ...
DOI:
10.1017/S0007114515005462
PubMed:
26856234

9. BA321, a novel carborane analog that binds to androgen and estrogen receptors, acts as a new selective androgen receptor modulator of bone in male mice

Author:
Kenta Watanabe; Michiko Hirata; Tsukasa Tominari; Chiho Matsumoto; Yasuyuki Endo; Gillian Murphy; Hideaki Nagase; Masaki Inada; Chisato Miyaura
Source:
Biochemical and biophysical research communications 2016 v.478 no.1 pp. 279-285
ISSN:
0006-291X
Subject:
agonists; androgen receptors; atrophy; bone density; bone resorption; boron; estrogen receptors; females; femur; hydrophobicity; males; mice; osteoporosis; ovariectomy; seminal vesicles
Abstract:
... Carboranes are a class of carbon-containing polyhedral boron cluster compounds with globular geometry and hydrophobic surface that interact with hormone receptors such as estrogen receptor (ER) and androgen receptor (AR). We have synthesized BA321, a novel carborane compound, which binds to AR. We found here that it also binds to ERs, ERα and ERβ. In orchidectomized (ORX) mice, femoral bone mass w ...
DOI:
10.1016/j.bbrc.2016.07.027

10. Behaviour, growth performance, foot pad quality, bone density, and carcass traits of broiler chickens reared with barrier perches and fed different dietary crude protein levels

Author:
C.J. Bench; M.A. Oryschak; D.R. Korver; E. Beltranena
Source:
Canadian journal of animal science 2016 v.97 no.2 pp. 268-280
ISSN:
1918-1825
Subject:
average daily gain; body weight; bone density; breasts; broiler chickens; carcass weight; crude protein; dermatitis; diet; dressing percentage; feed intake; growth performance; meat; perch; rearing
Abstract:
... Perches serve as a behavioural enrichment and may yield benefits on broiler foot health and growth performance. The benefit may be greater for birds fed high crude protein (HCP) diets, which results in poorer litter conditions. This study investigated the effect of two perch configurations (I shaped vs. X shaped, compared with no perch) and dietary crude protein (CP) level (standard vs. high) on b ...
DOI:
10.1139/cjas-2015-0202

11. Biomechanical evolution of solid bones in large animals: a microanatomical investigation

Author:
Alexandra Houssaye; Katja Waskow; Shoji Hayashi; Raphaël Cornette; Andrew H. Lee; John R. Hutchinson
Source:
Biological journal of the Linnean Society 2016 v.117 no.2 pp. 350-371
ISSN:
0024-4066
Subject:
absorption; allometry; animals; aquatic organisms; biomechanics; bone density; cortex; energy; evolution; paleoecology; posture
Abstract:
... Graviportal taxa show an allometric increase of the cross‐sectional area of supportive bones and are assumed to display microanatomical changes associated with an increase in bone mass. This evokes osteosclerosis (i.e. an increase in bone compactness observed in some aquatic amniotes). The present study investigates the changes in bones' microanatomical organization associated with graviportality ...
DOI:
10.1111/bij.12660

12. Body mass but not vitamin D status is associated with bone mineral content and density in young school children in northern Sweden

Author:
Frida K. Videhult; Inger Öhlund; Olle Hernell; Christina E. West
Source:
Food & nutrition research 2016 v.60 no.1 pp. 30045
ISSN:
1654-661X
Subject:
blood serum; body mass index; bone density; bone health; boys; calcium; cross-sectional studies; energy; food frequency questionnaires; food records; girls; latitude; lean body mass; liquid chromatography; mass spectrometry; pedometer; physical activity; prospective studies; puberty; school children; summer; vitamin D; vitamin status; Sweden
Abstract:
... High latitude of residence where sun exposure is limited affects vitamin D status. Although vitamin D levels have been associated with poor bone health, cut-off values for optimising bone health are yet to be decided. To assess vitamin D intake and status among young school children living at latitude 63–64 °N, in northern Sweden and to examine the association between vitamin D status and bone min ...
DOI:
10.3402/fnr.v60.30045

13. Bone density of elbow joints in Labrador retrievers and Golden retrievers: Comparison of healthy joints and joints with medial coronoid disease

Author:
A. Villamonte-Chevalier; W. Dingemanse; B.J.G. Broeckx; A. Van Caelenberg; A. Agut; L. Duchateau; H. van Bree; I. Gielen
Source:
veterinary journal 2016 v.216 pp. 1-7
ISSN:
1090-0233
Subject:
Golden Retriever; Labrador Retriever; age; body weight; bone density; dogs; humerus
Abstract:
... The aims of this study were: (1) to determine the inter-observer repeatability of particular regions of the canine elbow joints; (2) to assess the effect of age, bodyweight and breed on bone density in healthy young dogs; (3) to compare Hounsfield units (HU) and bone density (BD) measurements between normal elbow joints and diseased elbow joints; and (4) to determine the sensitivity and specificit ...
DOI:
10.1016/j.tvjl.2016.06.005

14. Bone health nutraceuticals alter microarray mRNA gene expression: A randomized, parallel, open-label clinical study

Author:
Yumei Lin; Valentina Kazlova; Shyam Ramakrishnan; Mary A. Murray; David Fast; Amitabh Chandra; Kevin W. Gellenbeck
Source:
Phytomedicine 2016 v.23 no.1 pp. 18-26
ISSN:
0944-7113
Subject:
Dimorphandra; Glycyrrhiza glabra; Punica granatum; Vitis vinifera; blood; blood sampling; bone density; bone formation; bone morphogenetic proteins; bone resorption; cathepsin G; collagen; extracellular matrix; food intake; fruits; functional foods; gene expression; gene expression regulation; genes; grape seeds; heparan sulfate; hyaluronoglucosaminidase; licorice; messenger RNA; microarray technology; osteoblasts; plant extracts; polyphenols; pomegranates; postmenopause; proteoglycans; quercetin; vegetables; women
Abstract:
... Dietary intake of fruits and vegetables has been suggested to have a role in promoting bone health. More specifically, the polyphenols they contain have been linked to physiological effects related to bone mineral density and bone metabolism. In this research, we use standard microarray analyses of peripheral whole blood from post-menopausal women treated with two fixed combinations of plant extra ...
DOI:
10.1016/j.phymed.2015.11.011

15. CLA Has a Useful Effect on Bone Markers in Patients with Rheumatoid Arthritis

Author:
N. Aryaeian; F. Shahram; M. Djalali
Source:
Lipids 2016 v.51 no.12 pp. 1397-1405
ISSN:
0024-4201
Subject:
bone density; chronic diseases; clinical trials; computer software; conjugated linoleic acid; diet; enzyme-linked immunosorbent assay; insulin-like growth factor I; isomers; medical history; nutrition assessment; oleic acid; osteocalcin; osteoporosis; patients; placebos; questionnaires; rheumatoid arthritis; risk; sunflower oil
Abstract:
... Rheumatoid arthritis is a systemic, chronic disease which may increase the risk of osteoporosis. This study was carried out in order to examine the effect of conjugated linoleic acid (CLA) on bone markers in rheumatoid arthritis disease which is the most common autoimmune disease. The present study is a randomized double-blind clinical trial. Subjects included 52 patients with active rheumatoid ar ...
DOI:
10.1007/s11745-016-4201-6

16. Can a healthy life prevent us from post-menopausal osteoporosis? Myths and truths

Author:
Soledad Herrero; Yolanda Pico
Source:
PharmaNutrition 2016 v.4 no.2 pp. 45-53
ISSN:
2213-4344
Subject:
adverse effects; alternative medicine; ascorbic acid; biomarkers; bone density; bone resorption; calcium; children; clinical trials; drugs; eating habits; epidemiological studies; fish consumption; gender; green tea; isoflavones; mineral content; olive oil; osteoporosis; ovariectomy; physical activity; postmenopause; prunes; rats; risk factors; women
Abstract:
... Postmenopausal osteoporosis is related to unmodifiable risk factors (genetics, race, gender and age). However, other controllable factors such as activity, body mass, hormone and calcium levels and dietary habits can reduce fracture risk. For example, significant increases in bone mass density have been linked to physical activity in children, supplements of Vitamin C taken for more than 10 years, ...
DOI:
10.1016/j.phanu.2016.02.003

17. Collagens VI and XII form complexes mediating osteoblast interactions during osteogenesis

Author:
Yayoi Izu; Yoichi Ezura; Manuel Koch; David E. Birk; Masaki Noda
Source:
Cell and tissue research 2016 v.364 no.3 pp. 623-635
ISSN:
0302-766X
Subject:
bone density; bone formation; cell communication; collagen; fluorescent antibody technique; genes; homeostasis; mice; muscle tissues; muscular dystrophy; mutation; osteoblasts; patients; phenotype
Abstract:
... Bone formation is precisely regulated by cell-cell communication in osteoblasts. We have previously demonstrated that genetic deletion of Col6a1 or Col12a1 impairs osteoblast connections and/or communication in mice, resulting in bone mass reduction and bone fragility. Mutations of the genes encoding collagen VI cause Ullrich congenital muscular dystrophy (UCMD) and Bethlem myopathy (BM), which ha ...
DOI:
10.1007/s00441-015-2345-y
PubMed:
26753503
PubMed Central:
PMC4875952

18. Combinations of physical activity, sedentary behaviour and sleep: relationships with health indicators in school-aged children and youth1

Author:
Travis John Saunders; Casey Ellen Gray; Veronica Joan Poitras; Jean-Philippe Chaput; Ian Janssen; Peter T. Katzmarzyk; Timothy Olds; Sarah Connor Gorber; Michelle E. Kho; Margaret Sampson; Mark S. Tremblay; Valerie Carson
Source:
Applied Physiology, Nutrition, and Metabolism 2016 v.41 no.6 pp. S283
ISSN:
1715-5320
Subject:
adiposity; biomarkers; bone density; cognition; cohort studies; cross-sectional studies; databases; distress; metabolism; nutrition; physical activity; physical fitness; risk; school children; self-esteem; sleep; systematic review; youth
Abstract:
... The purpose of this systematic review was to determine how combinations of physical activity (PA), sedentary behaviour (SB), and sleep were associated with important health indicators in children and youth aged 5–17 years. Online databases (MEDLINE, EMBASE, SPORTdiscus, CINAHL, and PsycINFO) were searched for relevant studies examining the relationship between time spent engaging in different comb ...
DOI:
10.1139/apnm-2015-0626

19. Cysteic Acid in Dietary Keratin is Metabolized to Glutathione and Liver Taurine in a Rat Model of Human Digestion

Author:
Frances M. Wolber; Michelle McGrath; Felicity Jackson; Kim Wylie; Anne Broomfield
Source:
Nutrients 2016 v.8 no.2 pp. -
ISSN:
2072-6643
Subject:
animal models; blood; body fat; bone density; casein; cecum; cysteic acid; cysteine; digestibility; digestible protein; feathers; food intake; glutathione; hemoglobin; keratin; leukocyte count; liver; poultry; poultry industry; protein content; rats; taurine; tissue weight; weight gain
Abstract:
... Poultry feathers, consisting largely of keratin, are a low-value product of the poultry industry. The safety and digestibility of a dietary protein produced from keratin (KER) was compared to a cysteine-supplemented casein-based diet in a growing rat model for four weeks. KER proved to be an effective substitute for casein at 50% of the total dietary protein, with no changes in the rats’ food inta ...
DOI:
10.3390/nu8020104
PubMed:
26907334
PubMed Central:
PMC4772066

20. Danshen enhanced the estrogenic effects of Qing E formula in ovariectomized rats

Author:
Jian-mei Zhang; Jin Li; Er-wei Liu; Hong Wang; Guan-wei Fan; Yue-fei Wang; Yan Zhu; Shang-wei Ma; Xiu-mei Gao
Source:
BMC complementary and alternative medicine 2016 v.16 no.1 pp. 181
ISSN:
1472-6882
Subject:
Salvia miltiorrhiza; agonists; alternative medicine; blood; body weight; bone density; computed tomography; endometrium; epithelium; estrogen receptors; estrogenic properties; food intake; gene induction; low density lipoprotein cholesterol; luciferase; mammary glands; menopause; models; ovariectomy; pathophysiology; quality of life; rats; synergism; tibia; triacylglycerols
Abstract:
... BACKGROUND: Menopause is characterized by a decrease in life quality due to the appearance of uncomfortable symptoms. Nowadays, Understanding menopause-associated pathophysiology and developing new strategies to improve the treatment of menopausal-associated symptoms is an important issue. Our study was to evaluate the synergistic effects of Danshen (salvia miltiorrhiza bunge) and the phytoestroge ...
DOI:
10.1186/s12906-016-1146-5
PubMed:
27339619
PubMed Central:
PMC4918020

21. Differential effects of calcium- and vitamin D-fortified milk with FOS-inulin compared to regular milk, on bone biomarkers in Chinese pre- and postmenopausal women

Author:
Marlena C. Kruger; Yoke Mun Chan; Barbara Kuhn-Sherlock; Lee Ting Lau; ChinChin Lau; Y. S. Chin; Joanne M. Todd; Linda M. Schollum
Source:
European journal of nutrition 2016 v.55 no.5 pp. 1911-1921
ISSN:
1436-6207
Subject:
biomarkers; blood serum; bone density; bone resorption; calcium; cholecalciferol; fortified foods; magnesium; milk; minerals; parathyroid hormone; postmenopause; premenopause; vitamin status; women; zinc
Abstract:
... PURPOSE: To compare the effects of a high-calcium vitamin D-fortified milk with added FOS-inulin versus regular milk on serum parathyroid hormone, and bone turnover markers in premenopausal (Pre-M) and postmenopausal (PM) women over 12 weeks. METHODS: Premenopausal women (n = 136, mean age 41 (±5) years) and postmenopausal women [n = 121, mean age 59 (±4) years] were recruited, and each age group ...
DOI:
10.1007/s00394-015-1007-x

22. Direct Covalent Grafting of Phytate to Titanium Surfaces through Ti–O–P Bonding Shows Bone Stimulating Surface Properties and Decreased Bacterial Adhesion

Author:
Córdoba Alba; Hierro-Oliva Margarita; Pacha-Olivenza Miguel Ángel; Fernández-Calderón María Coronada; Perelló Joan; Isern Bernat; González-Martín María Luisa; Monjo Marta; Ramis Joana M.
Source:
ACS Applied Materials & Interfaces 2016 v.8 no.18 pp. 11326-11335
ISSN:
1944-8252
Subject:
X-ray photoelectron spectroscopy; adhesion; bacterial adhesion; bioactive properties; biofilm; bone density; bone resorption; chemical bonding; coatings; gamma radiation; hydroxyapatite; legumes; mass spectrometry; microorganisms; myo-inositol; nitric acid; pH; phytic acid; prostheses; seeds; storage time; titanium; titanium dioxide; vegetables; viability
Abstract:
... Myo-inositol hexaphosphate, also called phytic acid or phytate (IP6), is a natural molecule abundant in vegetable seeds and legumes. Among other functions, IP6 inhibits bone resorption. It is adsorbed on the surface of hydroxyapatite, inhibiting its dissolution and decreasing the progressive loss of bone mass. We present here a method to directly functionalize Ti surfaces covalently with IP6, with ...
DOI:
10.1021/acsami.6b02533

23. Effects of Proton Pump Inhibitor Administration and Intake of a Combination of Yogurt and Galactooligosaccharides on Bone and Mineral Metabolism in Rats

Author:
Satoshi Takasugi; Miho Shioyama; Masami Kitade; Masashi Nagata; Taketo Yamaji
Source:
Nutrients 2016 v.8 no.10 pp. -
ISSN:
2072-6643
Subject:
adults; bioavailability; blood serum; bone density; calcium; drugs; experimental diets; femur; fibroblast growth factors; galactooligosaccharides; laboratory animals; males; mineral metabolism; phosphorus; proton pump inhibitors; rats; subcutaneous injection; vertebrae; yogurt
Abstract:
... The aim of this study was to investigate the effects of proton pump inhibitor (PPI), the most potent acid-suppressing drug, administration and intake of a combination of yogurt and galactooligosaccharides (YG) on bone and mineral metabolism in adult rats. Twelve-week-old male Wistar rats were divided into three groups: a control group fed the control diet with vehicle administration, a PPI group f ...
DOI:
10.3390/nu8100653
PubMed:
27775655
PubMed Central:
PMC5084039

24. Estrogen-like osteoprotective effects of glycine in in vitro and in vivo models of menopause

Author:
Min-Ho Kim; Hyung-Min Kim; Hyun-Ja Jeong
Source:
Amino acids 2016 v.48 no.3 pp. 791-800
ISSN:
0939-4451
Subject:
alkaline phosphatase; amino acids; blood serum; bone density; cell proliferation; dose response; estradiol; gene expression; ingredients; menopause; messenger RNA; mice; minerals; models; oral administration; osteoblasts; ovariectomy; peptides; phosphorylation; placenta; weight gain
Abstract:
... Recently, the placenta mesotherapy has been widely used to treat menopause. Placenta contains amino acids, peptides, minerals, and estrogen. Here, we investigated the estrogen-like osteoprotective effects of glycine (a main ingredient of placenta) in in vitro and in vivo models of menopause. We assessed the effect of glycine on MG-63 osteoblast cell line, MCF-7 estrogen-dependent cell line, and ov ...
DOI:
10.1007/s00726-015-2127-6

25. Evaluation of chronological changes in bone fractures and age-related bone loss: A test case from Poland

Author:
Anna E. Spinek; Wiesław Lorkiewicz; Joanna Mietlińska; Ewa Sewerynek; Arkadiusz Kłys; David Caramelli; Elżbieta Żądzińska
Source:
Journal of archaeological science 2016 v.72 pp. 117-127
ISSN:
0305-4403
Subject:
archaeology; bone density; bone fractures; bone resorption; calcitriol receptors; calcium; diet; females; genes; osteoporosis; physical activity; polymerase chain reaction; ultraviolet radiation; women; Poland
Abstract:
... Paleopathological studies suggest different patterns of age-related bone loss and osteoporosis in past populations compared with those of modern times. However, the observed interpopulational differences are often difficult to interpret due to considerable environmental and biological heterogeneity between populations from which the analyzed skeletal samples come. In the present paper, we try to d ...
DOI:
10.1016/j.jas.2016.06.007

26. Experimental osteoporosis in sheep – mechanical and histological approach

Author:
Z. Kiełbowicz; A. Piątek; P. Kuropka; E. Mytnik; A. Nikodem; J. Bieżyński; P. Skrzypczak; C. Pezowicz; J. Kuryszko; P. Reichert
Source:
Polish journal of veterinary sciences 2016 v.19 no.1 pp. 109-118
ISSN:
2300-2557
Subject:
animal models; bone density; bone strength; cartilage; females; histology; methylprednisolone; mineral content; osteoporosis; sheep; therapeutics
Abstract:
... The implementation of new methods of osteoporotic therapy requires tests on animal model. The use of sheep as model has numerous advantages over other animals. The aim of this study was to describe the change in parameters in sheep with osteoporosis induced using steroids and ovariorectomy methods as opposed to the parameters in healthy sheep. The study was performed on female „merinos” breed shee ...
DOI:
10.1515/pjvs-2016-0014

27. Fgf23 and parathyroid hormone signaling interact in kidney and bone

Author:
Olena Andrukhova; Carmen Streicher; Ute Zeitz; Reinhold G. Erben
Source:
Molecular and Cellular Endocrinology 2016 v.436 pp. 224-239
ISSN:
0303-7207
Subject:
blood serum; bone density; calcium; complications (disease); cyclic AMP; diet; excretion; fibroblasts; genotype; hypocalcemia; lactose; mice; mineral metabolism; mitogen-activated protein kinase; mutants; osteoblasts; osteoclasts; parathyroid hormone; phosphorylation; proximal tubules; tibia; vitamin D
Abstract:
... Fibroblast growth factor-23 (FGF23) is a bone-derived hormone, suppressing renal phosphate reabsorption and vitamin D hormone synthesis in proximal tubules, and stimulating calcium reabsorption in distal tubules of the kidney. Here, we analyzed the long term sequelae of deficient Fgf23 signaling on bone and mineral metabolism in 9-month-old mice lacking both Fgf23 or Klotho and a functioning vitam ...
DOI:
10.1016/j.mce.2016.07.035

28. High fat diet enriched with saturated, but not monounsaturated fatty acids adversely affects femur, and both diets increase calcium absorption in older female mice

Author:
Yang Wang; Peter Dellatore; Veronique Douard; Ling Qin; Malcolm Watford; Ronaldo P. Ferraris; Tiao Lin; Sue A. Shapses
Source:
Nutrition research 2016 v.36 pp. 742-750
ISSN:
0271-5317
Subject:
absorption; adverse effects; body weight changes; bone density; calcium; cytochrome P-450; dietary fat; females; femur; genes; high fat diet; mice; mineral content; monounsaturated fatty acids; obesity; saturated fatty acids
Abstract:
... Diet induced obesity has been shown to reduce bone mineral density (BMD) and Ca absorption. However, previous experiments have not examined the effect of high fat diet (HFD) in the absence of obesity or addressed the type of dietary fatty acids. The primary objective of this study was to determine the effects of different types of high fat feeding, without obesity, on fractional calcium absorption ...
DOI:
10.1016/j.nutres.2016.03.002
PubMed:
27262536
PubMed Central:
PMC4919156

29. Housing conditions alter properties of the tibia and humerus during the laying phase in Lohmann white Leghorn hens

Author:
P. Regmi; N. Smith; N. Nelson; R.C. Haut; M.W. Orth; D.M. Karcher
Source:
Poultry science 2016 v.95 no.1 pp. 198-206
ISSN:
0032-5791
Subject:
White Leghorn; adulthood; aviaries; bone density; computed tomography; cortex; egg industry; geometry; humerus; mechanical properties; osteoporosis; resorption; tibia
Abstract:
... Osteoporosis in caged hens is one driving factor for the United States egg industry to explore options regarding alternative housing systems for laying hens. The aim of our research was to study the influence of housing systems on tibiae and humeri of 77-week-old Lohmann White hens. Pullets raised in an aviary system were either continued in aviary hen systems (AV) or conventional cages (AC) where ...
DOI:
10.3382/ps/pev209

30. Lean Mass and Body Fat Percentage Are Contradictory Predictors of Bone Mineral Density in Pre-Menopausal Pacific Island Women

Author:
Maria Casale; Pamela R. von Hurst; Kathryn L. Beck; Sarah Shultz; Marlena C. Kruger; Wendy O’Brien; Cathryn A. Conlon; Rozanne Kruger
Source:
Nutrients 2016 v.8 no.8 pp. -
ISSN:
2072-6643
Subject:
adipose tissue; ascorbic acid; body fat; bone density; bone health; calcium; densitometry; dual-energy X-ray absorptiometry; food frequency questionnaires; food intake; muscle tissues; physical activity; premenopause; protein intake; regression analysis; variance; weight loss; women; Pacific Ocean Islands
Abstract:
... Anecdotally, it is suggested that Pacific Island women have good bone mineral density (BMD) compared to other ethnicities; however, little evidence for this or for associated factors exists. This study aimed to explore associations between predictors of bone mineral density (BMD, g/cm2), in pre-menopausal Pacific Island women. Healthy pre-menopausal Pacific Island women (age 16–45 years) were recr ...
DOI:
10.3390/nu8080470
PubMed:
27483314
PubMed Central:
PMC4997383

31. Low level laser therapy accelerates bone healing in spinal cord injured rats

Author:
Carla Christina Medalha; Ana Lúcia Yaeko Silva Santos; Suellen de Oliveira Veronez; Kelly Rossetti Fernandes; Angela Maria Paiva Magri; Ana Claudia Muniz Renno
Source:
Journal of photochemistry and photobiology 2016 v.159 pp. 179-185
ISSN:
1011-1344
Subject:
animal injuries; biomechanics; bone density; bone resorption; females; models; morphometry; rats; risk; spinal cord; surgery; tibia; transcription factors
Abstract:
... Bone loss occurs rapidly and consistently after the occurrence of a spinal cord injury (SCI), leading to a decrease in bone mineral density (BMD) and a higher risk of fractures. In this context, the stimulatory effects of low level laser therapy (LLLT) also known as photobiomodulation (PBM) have been highlighted, mainly due to its osteogenic potential. The aim of the present study was to evaluate ...
DOI:
10.1016/j.jphotobiol.2016.03.041

32. Maternal dietary vitamin D carry-over alters offspring growth, skeletal mineralisation and tissue mRNA expressions of genes related to vitamin D, calcium and phosphorus homoeostasis in swine

Author:
Laura A. Amundson; Laura L. Hernandez; Jimena Laporta; Thomas D. Crenshaw
Source:
British journal of nutrition 2016 v.116 no.5 pp. 774-787
ISSN:
1475-2662
Subject:
bone density; breeding; calcium; cholecalciferol; colostrum; diet; femur; genes; humans; kidneys; lactation; long term effects; maternal effect; mechanical properties; messenger RNA; mineralization; models; osteocalcin; phosphorus; progeny; sows; weaning
Abstract:
... Maternal dietary vitamin D carry-over effects were assessed in young pigs to characterise skeletal abnormalities in a diet-induced model of kyphosis. Bone abnormalities were previously induced and bone mineral density (BMD) reduced in offspring from sows fed diets with inadequate vitamin D₃. In a nested design, pigs from sows (n 23) fed diets with 0 (−D), 8·125 (+D) or 43·750 (++D) µg D₃/kg from b ...
DOI:
10.1017/S0007114516002658
PubMed:
27480125

33. Methyl jasmolate treated buckwheat sprout powder enhances glucose metabolism by potentiating hepatic insulin signaling in estrogen-deficient rats

Author:
Hye Jeong Yang; Jeong Ho Lim; Kee Jae Park; Suna Kang; Da Sol Kim; Sunmin Park
Source:
Nutrition 2016 v.32 no.1 pp. 129-137
ISSN:
0899-9007
Subject:
bioactive compounds; body weight; bone density; bone metabolism; buckwheat; buckwheat sprouts; dextrins; dietary supplements; energy expenditure; estrogens; femur; glucose; high fat diet; homeostasis; hyperglycemia; insulin; insulin resistance; lipids; metabolism; ovariectomy; phosphorylation; phytoalexins; polyphenols; rats; rutin; skin temperature; weight gain
Abstract:
... Methyl jasmolate (MeJA)-treated vegetables produce higher concentrations of various bioactive compounds. We investigated whether long-term oral consumption of MeJA-treated and untreated buckwheat sprout powder improves energy, glucose, lipid, and bone metabolism induced by estrogen deficiency in ovariectomized (OVX) rats fed high-fat diets, and explored the mechanisms involved.OVX rats were divide ...
DOI:
10.1016/j.nut.2015.07.012

34. MiR-132 regulates osteogenic differentiation via downregulating Sirtuin1 in a peroxisome proliferator-activated receptor β/δ–dependent manner

Author:
Kai Gong; Bo Qu; Dongfa Liao; Da Liu; Cairu Wang; Jingsong Zhou; Xianming Pan
Source:
Biochemical and biophysical research communications 2016 v.478 no.1 pp. 260-267
ISSN:
0006-291X
Subject:
alkaline phosphatase; bone density; bone formation; bone fractures; bone resorption; cultured cells; free fatty acids; genes; glucose; microRNA; noninsulin-dependent diabetes mellitus; osteoblasts; osteoporosis; peroxisome proliferator-activated receptors; small interfering RNA
Abstract:
... MicroRNAs (miRNAs) play significant roles in multiple diseases by regulating the expression of their target genes. Type 2 diabetes mellitus (T2DM) is a chronic endocrine and metabolic disease with complex mechanisms. T2DM can result in diabetic osteoporosis (DO), which is characterized by bone loss, decreased bone mineral density and increased bone fractures. The promotion of osteogenic differenti ...
DOI:
10.1016/j.bbrc.2016.07.057

35. Micro‐CT Structural Analysis of the Canine Medial Coronoid Disease

Author:
Noel Fitzpatrick; Tanya C. Garcia; Anjolie Daryani; Judith Bertran; Shinya Watari; Kei Hayashi
Source:
Veterinary surgery 2016 v.45 no.3 pp. 336-346
ISSN:
0161-3499
Subject:
body weight; bone density; dogs; micro-computed tomography; surgery
Abstract:
... OBJECTIVE: To use micro‐computed tomography (CT) to evaluate the fissure–fracture pattern in dogs affected by medial coronoid disease (MCD). STUDY DESIGN: Prospective case‐controlled study. SAMPLE POPULATION: Client owned (n = 21) and cadaver dogs (n = 5). METHODS: Segments were excised by subtotal coronoid ostectomy from dogs with MCD. Two categories were identified: fissured (Fi) or fractured (F ...
DOI:
10.1111/vsu.12449

36. Mutan: A mixed linkage α-[(1,3)- and (1,6)]-d-glucan from Streptococcus mutans, that induces osteoclast differentiation and promotes alveolar bone loss

Author:
Hyun-Jung Kwon; Jung Min Kim; Kook-Il Han; Eui-Gil Jung; Yong Hyun Kim; Bharat Bhusan Patnaik; Mi Sook Yoon; Sung Kyun Chung; Wan Jong Kim; Man-Deuk Han
Source:
Carbohydrate polymers 2016 v.137 pp. 561-569
ISSN:
0144-8617
Subject:
Fourier transform infrared spectroscopy; Streptococcus mutans; bone density; bone resorption; chemokines; dose response; gene expression regulation; genes; glucose; inflammation; interleukin-1alpha; interleukin-1beta; interleukin-6; ligands; lipopolysaccharides; micro-computed tomography; microarray technology; models; morphometry; nuclear magnetic resonance spectroscopy; osteoclasts; periodontitis; rats
Abstract:
... Mutan is an extracellular polysaccharide of Streptococcus mutans (S. mutans) that consists of α-(1,3)-linked glucose residues in main chains and α-(1,6) bonds in side chains. In the present study, mutan was isolated from S. mutans, and its structural characteristics were determined using Fourier-transform infrared spectroscopy (FT-IR) and 13C nuclear magnetic resonance (NMR) spectroscopy. The effe ...
DOI:
10.1016/j.carbpol.2015.11.013

37. Natural products for treatment of osteoporosis: The effects and mechanisms on promoting osteoblast-mediated bone formation

Author:
Jing An; Hao Yang; Qian Zhang; Cuicui Liu; Jingjing Zhao; Lingling Zhang; Bo Chen
Source:
Life sciences 2016 v.147 pp. 46-58
ISSN:
0024-3205
Subject:
Oriental traditional medicine; active ingredients; adverse effects; anthraquinones; bone density; bone formation; bone resorption; coumarins; developmental orthopedic disease; diterpenoids; flavonoids; glycosides; mitogen-activated protein kinase; monoterpenoids; nitric oxide; osteoblasts; osteoporosis; phenolic acids; phenols; research and development; sesquiterpenoids; signal transduction; transcription (genetics); transcription factors
Abstract:
... Osteoporosis is a systemic metabolic bone disease characterized by a reduction in bone mass, bone quality, and microarchitectural deterioration. An imbalance in bone remodeling that is caused by more osteoclast-mediated bone resorption than osteoblast-mediated bone formation results in such pathologic bone disorder. Traditional Chinese medicines (TCM) have long been used to prevent and treat osteo ...
DOI:
10.1016/j.lfs.2016.01.024

38. Osteoblastogenic activity of ark shell protein hydrolysates with low molecular weight in mouse mesenchymal stem cells

Author:
Jun-Ho Hyung; Chang-Bum Ahn; Jae-Young Je
Source:
RSC advances 2016 v.6 no.35 pp. 29365-29370
ISSN:
2046-2069
Subject:
alkaline phosphatase; biomarkers; bone density; bone formation; bone morphogenetic proteins; collagen; functional foods; health promotion; humans; hydrolysis; ingredients; mesenchymal stromal cells; mice; mineralization; mitogen-activated protein kinase; molecular weight; osteocalcin; osteoporosis; protein hydrolysates
Abstract:
... Aging of human bone is characterized by decreased bone formation and bone mass. In this study, ark shell protein hydrolysates (ASPHs) were prepared by peptic hydrolysis with optimal conditions and were fractionated into 3–10 kDa, 1–3 kDa and <1 kDa fractions. Modulating the effects of ASPH with low molecular weight (ASPH < 1 kDa), which exhibited the highest stimulation effect on alkaline phosphat ...
DOI:
10.1039/c6ra00898d

39. PUFAs, Bone Mineral Density, and Fragility Fracture: Findings from Human Studies

Author:
Amanda B Longo; Wendy E Ward
Source:
Advances in nutrition 2016 v.7 no.2 pp. 299-312
ISSN:
2156-5376
Subject:
bone density; cell culture; eating habits; fatty fish; fish consumption; humans; inflammation; nutrition assessment; osteoporosis; polyunsaturated fatty acids; risk reduction
Abstract:
... Osteoporosis is a global health problem that leads to an increased incidence of fragility fracture. Recent dietary patterns of Western populations include higher than recommended intakes of n–6 (ω-6) polyunsaturated fatty acids (PUFAs) relative to n–3 (ω-3) PUFAs that may result in a chronic state of sterile whole body inflammation. Findings from human bone cell culture experiments have revealed b ...
DOI:
10.3945/an.115.009472
PubMed:
26980813
PubMed Central:
PMC4785467

40. Periostin action in bone

Author:
Nicolas Bonnet; Patrick Garnero; Serge Ferrari
Source:
Molecular and Cellular Endocrinology 2016 v.432 pp. 75-82
ISSN:
0303-7207
Subject:
asthma; biomarkers; blood serum; bone density; bone formation; infarction; insects; integrins; metastasis; mice; neoplasms; osteoblasts; osteoporosis; parathyroid hormone; postmenopause; receptors; renal failure; risk; skeleton
Abstract:
... Periostin is a highly conserved matricellular protein that shares close homology with the insect cell adhesion molecule fasciclin 1. Periostin is expressed in a broad range of tissues including the skeleton, where it serves both as a structural molecule of the bone matrix and a signaling molecule through integrin receptors and Wnt-beta-catenin pathways whereby it stimulates osteoblast functions an ...
DOI:
10.1016/j.mce.2015.12.014

41. Porcine placenta hydrolysates enhance osteoblast differentiation through their antioxidant activity and effects on ER stress

Author:
Hwa-Young Lee; Han-Jung Chae; Sun-Young Park; Jong-Hyun Kim
Source:
BMC complementary and alternative medicine 2016 v.16 no.1 pp. 291
ISSN:
1472-6882
Subject:
NAD(P)H oxidase (H2O2-forming); RNA; alkaline phosphatase; alternative medicine; antioxidant activity; apoptosis; bone density; bone metabolism; bone strength; caspases; cell viability; enzyme activity; hydrogen peroxide; hydrolysates; immunoblotting; osteoblasts; osteocalcin; osteoporosis; placenta; reverse transcriptase polymerase chain reaction; superoxide dismutase; swine
Abstract:
... BACKGROUND: Osteoporosis is a disease characterized by decreased bone strength, decreased bone mass, and bone deterioration. Oxidative damage is an important contributor to functional changes in the development of osteoporosis. Here we found that porcine placenta hydrolysates (PPHs) protect MC3T3-E1 osteoblastic cells against hydrogen peroxide (H₂O₂)-induced oxidative damage. METHODS: In vitro cel ...
DOI:
10.1186/s12906-016-1274-y
PubMed:
27535035
PubMed Central:
PMC4989514

42. Preference for and use of oral enrichment objects in juvenile silver foxes (Vulpes vulpes)

Author:
Anne Lene Hovland; Anne Marit S. Rød; Tarja Koistinen; Leena Ahola
Source:
Applied animal behaviour science 2016 v.180 pp. 122-129
ISSN:
0168-1591
Subject:
Vulpes vulpes; animal behavior; bone density; cages; cattle; durability; femur; foxes; juveniles; meat; straw
Abstract:
... Providing captive foxes with relevant enrichment objects may support their ability to cope with barren housing systems and thus have positive welfare effects. The relevance of enrichment objects is, among others, related to animals’ preference that should be examined prior to supplementing their housing environment. In this study, we assessed 30 juvenile, singly housed silver foxes’ short-term pre ...
DOI:
10.1016/j.applanim.2016.04.020

43. Proceedings of the Thirteenth International Society of Sports Nutrition (ISSN) Conference and Expo : Clearwater Beach, FL, USA. 9-11 June 2016

Author:
Lalitha Ramaswamy; Supriya Velraja; Guillermo Escalante; Phil Harvey; Michelle Alencar; Bryan Haddock; Krzysztof Durkalec-Michalski; Jan Jeszka; Bogna Zawieja; Tomasz Podgórski; Ana Paula Trussardi Fayh; Alexandre Hideki Okano; Amanda Maria de Jesus Ferreira; Ralf Jäger; Martin Purpura; Roger C. Harris; Molly M. Krause; Kiley A. Lavanger; Nina O. Allen; Allison E. Lieb; Katie A. Mullen; Joan M. Eckerson; Elisa Morales; Jeffrey Forsse; Thomas Andre; Sarah McKinley; Paul Hwang; Grant Tinsley; Mike Spillane; Peter Grandjean; Darryn Willoughby; A. Jagim; G. Wright; J. Kisiolek; M. Meinking; J. Ochsenwald; M. Andre; M. T. Jones; J. M. Oliver; Victor Araújo Ferreira; Daniel Costa de Souza; Victor Oliveira Albuquerque dos Santos; Rodrigo Alberto Vieira Browne; Eduardo Caldas Costa; Suresh T. Mathews; Haley D. Bishop; Clara R. Bowen; Yishan Liang; Emily A. West; Rebecca R. Rogers; Mallory R. Marshall; John K. Petrella; A. Maleah Holland; Wesley C. Kephart; Petey W. Mumford; C. Brooks Mobley; Ryan P. Lowery; Jacob M. Wilson; Michael D. Roberts; Eric T. Trexler; Katie R. Hirsch; Bill I. Campbell; Meredith G. Mock; Abbie E. Smith-Ryan; Kate Zemek; Carol Johnston; David D. Pascoe; Christopher M. Lockwood; Michael E. Miller; Gabriel J. Sanders; Willard Peveler; Brooke Warning; Corey A. Peacock; David Sandler; Sara Perez Ojalvo; James Komorowski; Danielle Aguilar; Andres Vargas; Laurin Conlin; Amey Sanders; Paola Fink-Irizarry; Layne Norton; Ross Perry; Ryley McCallum; Matthew R. Wynn; Jack Lenton; Chris Gai; Seth Donelson; Shiva Best; Daniel Bove; Kaylee Couvillion; Jeff Dolan; Dante Xing; Kyshia Chernesky; Michael Pawela; Andres D. Toledo; Rachel Jimenez; M. Rabideau; A. Walker; J. Pellegrino; M. Hofacker; B. McFadden; S. Conway; C. Ordway; D. Sanders; R. Monaco; M. S. Fragala; S. M. Arent; Jason D. Stone; Andreas Kreutzer; Jonathan M. Oliver; Jacob Kisiolek; Andrew R. Jagim; Ozlem Tok; Joseph K. Pellegrino; Alan J. Walker; David J. Sanders; Bridget A. McFadden; Meaghan M. Rabideau; Sean P. Conway; Chris E. Ordway; Marissa Bello; Morgan L. Hofacker; Nick S. Mackowski; Anthony J. Poyssick; Eddie Capone; Robert M. Monaco; Maren S. Fragala; Shawn M. Arent; Romil K. Patel; Annie Newton; Darren T. Beck; Kaelin C. Young; Tobin Silver; Anya Ellerbroek; Richard Buehn; Leo Vargas; Armando Tamayo; Corey Peacock; Jose Antonio; Adam Pollock; A. Kreutzer; P. Zavala; S. Fleming; M. Jones; Cody T. Haun; Parker N. Hyde; Ciaran M. Fairman; Jordan R. Moon; Kristina L. Kendall; Geoffrey M. Hudson; Tara Hannings; Kyle Sprow; Loretta DiPietro; Doug Kalman; J. Oliver; Brian Wallace; Haley Bergstrom; Kelly Wallace; Matias Monsalves-Alvarez; Sebastian Oyharçabal; Victoria Espinoza; Trisha A. VanDusseldorp; Kurt A. Escobar; Kelly E. Johnson; Nathan Cole; Terence Moriarty; Matthew Stratton; Marvin R. Endito; Christine M. Mermier; Chad M. Kerksick; Matthew A. Romero; Melissa Linden; Grace Margaret-Eleanor Meers; R. Scott Rector; Joshua L Gills; Hocheng Lu; Kimberly Parker; Chris Dobbins; Joshua N. Guillory; Braden Romer; David Szymanski; Jordan Glenn; Daniel E. Newmire; Eric Rivas; Sarah E. Deemer; Robert Wildman; Victor Ben-Ezra; C. Kerksick; B. Gieske; R. Stecker; C. Smith; K. Witherbee; Michael T. Lane; M. Travis Byrd; Zachary Bell; Emily Frith; Lauren M. C. Lane; Tobin A. Silver; Megan Colas; Mauricio Mena; Winter Rodriguez; Andrea Vansickle; Brittany DiFiore; Stephanie Stepp; Grant Slack; Bridget Smith; Kayla Ruffner; Ronald Mendel; Lonnie Lowery; Malia M. N. Blue; Erica J. Roelofs; Katie Coles; Nic Martinez; Jordan M. Joy; Roxanne M. Vogel; Thomas H. Hoover; K. Shane Broughton; R. Dalton; R. Sowinski; T. Grubic; P. B. Collins; A. Colletta; A. Reyes; B. Sanchez; M. Kozehchain; Y. P. Jung; C. Rasmussen; P. Murano; C. P. Earnest; M. Greenwood; R. B. Kreider; Stacie Urbina; Emily Santos; Katelyn Villa; Alyssa Olivencia; Haley Bennett; Marissa Lara; Cliffa Foster; Colin Wilborn; Lem Taylor; Jason M Cholewa; Amy Hewins; Samantha Gallo; Ashley Micensky; Christian de Angelis; Christopher Carney; Bill Campbell; Fabricio Rossi; M. S. Koozehchian; A. O’Connor; S. Y. Shin; Y. Peter Jung; B. K. Sanchez; A. Coletta; M. Cho; P. S. Murano
Source:
Journal of the International Society of Sports Nutrition 2016 v.13 no.Supplement 1 pp. 33
ISSN:
1550-2783
Subject:
Western diets; acute effects; adults; antioxidants; appetite; arginine; athletes; biogenesis; biomarkers; blood glucose; blood serum; body fat; body water; bone density; bone metabolism; breakfast; caffeine; calorimetry; casein; cognition; college students; colostrum; creatine; creatine kinase; cross-over studies; diet recall; dieting; distress; electrolytes; energy drinks; energy intake; equations; exosomes; females; femur; food intake; gastrointestinal system; glucose; high protein diet; hormones; insulin-like growth factor I; ketogenic diet; leucine; lipid composition; liver; males; men; molecular weight; muscles; nitrates; nitric oxide; nutrition monitoring; nutritional status; overweight; oxidation; oxygen consumption; peppermint oil; physical fitness; power generation; prediction; protein hydrolysates; protein intake; protein supplements; protein synthesis; rats; resting metabolic rate; ribosomes; risk factors; silicates; silicon; sodium bicarbonate; sports; sports nutrition; strength training; triacylglycerols; waist circumference; whey; whey protein; women; United States
Abstract:
... TABLE OF CONTENTS: P1 Impact of antioxidant-enriched nutrient bar supplementation on the serum antioxidant markers and physical fitness components of track and field athletesLalitha Ramaswamy, Supriya VelrajaP2 The effects of phosphatidic acid supplementation on fitness levels in resistance trained womenGuillermo Escalante, Phil Harvey, Michelle Alencar, Bryan HaddockP3 The effects of phosphatidic ...
DOI:
10.1186/s12970-016-0144-9

44. Quantitative comparison of bone mineral density characteristics of the distal epiphysis of third metacarpal bones from Thoroughbred racehorses with or without condylar fracture

Author:
Sophie H. Bogers; Chris W. Rogers; Charlotte Bolwell; Wendi Roe; Erica Gee; Wayne Mcllwraith
Source:
American journal of veterinary research 2016 v.77 no.1 pp. 32-38
ISSN:
0002-9645
Subject:
Thoroughbred; bone density; computer software; epiphyses; image analysis; metacarpus; racehorses; spatial distribution; statistics
Abstract:
... OBJECTIVE To compare regional proportions and spatial distributions of volumetric bone mineral density (BMDv) of the palmar aspect of the distal epiphysis of the third metacarpal bone (McIII) in limbs with or without a condylar fracture from Thoroughbred racehorses. SAMPLE McIIIs from cadavers of Thoroughbred racehorses with (n = 6 bones) and without (8) a condylar fracture. PROCEDURES BMDv and sp ...
DOI:
10.2460/ajvr.77.1.32

45. Quantitative proteomics and integrative network analysis identified novel genes and pathways related to osteoporosis

Author:
Yong Zeng; Lan Zhang; Wei Zhu; Chao Xu; Hao He; Yu Zhou; Yao-Zhong Liu; Qing Tian; Ji-Gang Zhang; Fei-Yan Deng; Hong-Gang Hu; Li-Shu Zhang; Hong-Wen Deng
Source:
Journal of proteomics 2016 v.142 pp. 45-52
ISSN:
1874-3919
Subject:
Whites; bone density; bone resorption; females; gene expression regulation; genes; genome-wide association study; microfilaments; monocytes; osteoclasts; osteoporosis; protein synthesis; proteomics; spectroscopy
Abstract:
... Osteoporosis is mainly characterized by low bone mineral density (BMD), and can be attributed to excessive bone resorption by osteoclasts. Migration of circulating monocytes from blood to bone is important for subsequent osteoclast differentiation and bone resorption. Identification of those genes and pathways related to osteoclastogenesis and BMD will contribute to a better understanding of the p ...
DOI:
10.1016/j.jprot.2016.04.044
PubMed:
27153759
PubMed Central:
PMC5362378

46. Serum concentrations of 25-hydroxyvitamin D and its association with bone mineral density and serum parathyroid hormone levels during winter in urban males from Guiyang, Southwest China

Author:
Qiao Zhang; Lixin Shi; Nianchun Peng; Shujing Xu; Miao Zhang; Song Zhang; Hong Li; Huijun Zhuang; Mingxian Gong; Danrong Wu; Rui Wang
Source:
British journal of nutrition 2016 v.115 no.6 pp. 960-966
ISSN:
1475-2662
Subject:
blood serum; bone density; covariance; femur; hips; lifestyle; lumbar spine; males; medical history; parathyroid hormone; socioeconomics; surveys; vitamin D; winter; China
Abstract:
... Serum vitamin D (25-hydroxyvitamin D (25OHD)) may influence serum parathyroid hormone (PTH) levels and bone mineral density (BMD). In the present study, we assessed serum 25OHD concentration and its association with PTH and BMD in urban males from Guiyang (N26.57°), the capital city of Guizhou province, Southwest China. We recruited 634 males aged >20 years from the Guiyang Health Measures Survey, ...
DOI:
10.1017/S0007114515005383
PubMed:
26843386

47. Sialoglycoprotein Isolated from Eggs of Carassius auratus Ameliorates Osteoporosis: An Effect Associated with Regulation of the Wnt/β-Catenin Pathway in Rodents

Author:
Fei Wang; Yiming Wang; Yanlei Zhao; Qiping Zhan; Peng Yu; Jingfeng Wang; Changhu Xue
Source:
Journal of agricultural and food chemistry 2016 v.64 no.14 pp. 2875-2882
ISSN:
0021-8561
Subject:
Carassius auratus; biomechanics; bone density; bone formation; eggs; genes; metabolism; mice; microstructure; models; osteoblasts; osteoporosis; ovariectomy; postmenopause; rats
Abstract:
... In the current study, ovariectomized (OVX) rats and the senescence-accelerated mouse strain P6 (SAMP6) were employed to establish models of postmenopausal osteoporosis and senile osteoporosis, respectively. The effects of treatment with sialoglycoprotein isolated from the eggs of Carassius auratus (Ca-SGP) on these two types of osteoporosis were investigated in vivo. Results showed that Ca-SGP sig ...
DOI:
10.1021/acs.jafc.5b06132

48. Skeletal effects of growth hormone and insulin-like growth factor-I therapy

Author:
Richard C. Lindsey; Subburaman Mohan
Source:
Molecular and Cellular Endocrinology 2016 v.432 pp. 44-55
ISSN:
0303-7207
Subject:
animal models; bone density; bone formation; humans; in vitro studies; insulin-like growth factor I; insulin-like growth factor binding proteins; ligands; osteoporosis; proteinases; receptors; somatotropin; therapeutics; transgenic animals
Abstract:
... The growth hormone/insulin-like growth factor (GH/IGF) axis is critically important for the regulation of bone formation, and deficiencies in this system have been shown to contribute to the development of osteoporosis and other diseases of low bone mass. The GH/IGF axis is regulated by a complex set of hormonal and local factors which can act to regulate this system at the level of the ligands, r ...
DOI:
10.1016/j.mce.2015.09.017
PubMed:
26408965
PubMed Central:
PMC4808510

49. TIEG1 enhances Osterix expression and mediates its induction by TGFβ and BMP2 in osteoblasts

Author:
Malayannan Subramaniam; Kevin S. Pitel; Sarah G. Withers; Hicham Drissi; John R. Hawse
Source:
Biochemical and biophysical research communications 2016 v.470 pp. 528-533
ISSN:
0006-291X
Subject:
DNA-binding domains; bone density; bone formation; chromatin; cytokines; gene expression regulation; messenger RNA; mice; mineralization; osteoblasts; phenotype; precipitin tests; skeleton; transfection; transforming growth factor beta; zinc
Abstract:
... Deletion of TIEG1/KLF10 in mice results in an osteopenic skeletal phenotype with significant decreases in both bone mineral density and content throughout the skeleton. Calvarial osteoblasts isolated from TIEG1 knockout (KO) mice display numerous changes in gene expression and exhibit significant delays in their mineralization rates relative to wild-type (WT) controls. Here, we demonstrate that lo ...
DOI:
10.1016/j.bbrc.2016.01.112
PubMed:
26801561
PubMed Central:
PMC4747784

50. The effects of different levels of calcium supplementation on the bone mineral status of postpartum lactating Chinese women: a 12-month randomised, double-blinded, controlled trial

Author:
Zhe-Qing Zhang; Yu-Ming Chen; Ruo-Qin Wang; Zhen-Wu Huang; Xiao-Guang Yang; Yi-Xiang Su
Source:
British journal of nutrition 2016 v.115 no.1 pp. 24-31
ISSN:
1475-2662
Subject:
Chinese people; bone density; breast feeding; calcium; dried milk; dual-energy X-ray absorptiometry; hips; lactating women; lactation; lumbar spine; vitamin D
Abstract:
... Increasing dietary Ca intake may prevent the excessive mobilisation of bone mineral in nursing mothers. We aimed to investigate whether higher Ca intake could positively modulate the bone mineral changes in Chinese postpartum lactating women. The study was a 12-month randomised, double-blinded, parallel group trial conducted over 12 months. A total of 150 postpartum women were randomly selected to ...
DOI:
10.1017/S0007114515003967
PubMed:
26522081