Jump to Main Content
- Xia, Pengpeng; Wang, Yiting; Zhu, Congrui; Zou, Yajie; Yang, Ying; Liu, Wei; Hardwidge, Philip R.; Zhu, Guoqiang
- Veterinary research 2016 v.47 no.1 pp. 24
- piglets, etc ; antibodies; diarrhea; enterotoxigenic Escherichia coli; fimbriae; gene expression; intestinal mucosa; membrane alanyl aminopeptidase; receptors; serotypes; two hybrid system techniques; Show all 11 Subjects
- ... F4⁺ enterotoxigenic Escherichia coli (ETEC) strains cause diarrheal disease in neonatal and post-weaned piglets. Several different host receptors for F4 fimbriae have been described, with porcine aminopeptidase N (APN) reported most recently. The FaeG subunit is essential for the binding of the three F4 variants to host cells. Here we show in both yeast two-hybrid and pulldown assays that APN bind ...
- PubMed Central: