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- Saeed, Aamer; Ejaz, Syeda Abida; Shehzad, Muddasar; Hassan, Sidra; al-Rashida, Mariya; Lecka, Joanna; Sévigny, Jean; Iqbal, Jamshed
- RSC advances 2016 v.6 no.25 pp. 21026-21036
- computer simulation, etc ; alkaline phosphatase; binding sites; enzyme inhibitors; inhibitory concentration 50; intestines; levamisole; models; nuclear magnetic resonance spectroscopy; rats; Show all 10 Subjects
- ... A new series of 3-(2-(benzylideneamino)thiazol-4-yl)-2H-chromen-2-ones has been synthesized. The structures of the compounds were established by means of ¹H and ¹³C NMR spectroscopy. All compounds were evaluated for their potential to inhibit human recombinant ecto-nucleotidases, including human tissue-nonspecific alkaline phosphatase (h-TNAP), tissue specific human intestinal alkaline phosphatase ...