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- Yamada, Yoshiji, et al. Show all 2 Author
- Biochemical and biophysical research communications 2016 v.473 pp. 1261-1267
- histone deacetylase; peroxisome proliferator-activated receptors; transcription (genetics); ubiquitin-protein ligase
- ... Parkin-interacting substrate (PARIS), a member of the family of Krüppel-associated box (KRAB)-containing zinc-finger transcription factors, is a substrate of the ubiquitin E3 ligase parkin. PARIS represses the expression of peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α), although the underlying mechanisms remain largely unknown. In the present study, we demonstrate that PARIS ...