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1. Novel action of FOXL2 as mediator of Col1a2 gene autoregulation

Author:
Marongiu, Mara; Deiana, Manila; Marcia, Loredana; Sbardellati, Andrea; Asunis, Isadora; Meloni, Alessandra; Angius, Andrea; Cusano, Roberto; Loi, Angela; Crobu, Francesca; Fotia, Giorgio; Cucca, Francesco; Schlessinger, David; Crisponi, Laura
Source:
Developmental biology 2016
ISSN:
0012-1606
Subject:
longevity,   etc   ; DNA; animal ovaries; autoregulation; biosynthesis; cartilage; collagen; extracellular matrix; eyelids; fibronectins; fibrosis; follicular development; genes; laminin; menopause; mice; morphogenesis; skeletal development; transcription factors;     Show all 19 Subjects
Abstract:
... FOXL2 belongs to the evolutionarily conserved forkhead box (FOX) superfamily and is a master transcription factor in a spectrum of developmental pathways, including ovarian and eyelid development and bone, cartilage and uterine maturation.To analyse its action, we searched for proteins that interact with FOXL2. We found that FOXL2 interacts with specific C-terminal propeptides of several fibrillar ...
DOI:
10.1016/j.ydbio.2016.05.022
PubMed:
27212026
PubMed Central:
PMC5526220

2. Are commercial probiotics and prebiotics effective in the treatment and prevention of honeybee nosemosis C?

Author:
Ptaszyńska, Aneta A.; Borsuk, Grzegorz; Zdybicka-Barabas, Agnieszka; Cytryńska, Małgorzata; Małek, Wanda
Source:
Parasitology research 2016 v.115 no.1 pp. 397-406
ISSN:
0932-0113
Subject:
longevity,   etc   ; Apoidea; Lactobacillus rhamnosus; Nosema ceranae; hemolymph; honey bees; immune system; inulin; monophenol monooxygenase; nosema disease; prebiotics; probiotics; spores; sucrose; survival rate; syrups;     Show all 16 Subjects
Abstract:
... The study was conducted to investigate the effect of Lactobacillus rhamnosus (a commercial probiotic) and inulin (a prebiotic) on the survival rates of honeybees infected and uninfected with Nosema ceranae, the level of phenoloxidase (PO) activity, the course of nosemosis, and the effect on the prevention of nosemosis development in bees. The cells of L. rhamnosus exhibited a high rate of survival ...
DOI:
10.1007/s00436-015-4761-z
PubMed:
26437644
PubMed Central:
PMC4700093

3. Peanuts as functional food: a review

Author:
Arya, Shalini S.; Salve, Akshata R.; Chauhan, S.
Source:
Journal of food science and technology 2016 v.53 no.1 pp. 31-41
ISSN:
0022-1155
Subject:
longevity,   etc   ; absorption; active ingredients; antioxidants; arginine; bioactive compounds; boiling; byproducts; cholesterol; coenzyme Q10; diet; flavonoids; functional foods; minerals; oils; peanuts; phenolic acids; phytosterols; polyphenols; processed foods; proteins; resveratrol; roasting; vitamins;     Show all 24 Subjects
Abstract:
... Peanut is an important crop grown worldwide. Commercially it is used mainly for oil production but apart from oil, the by-products of peanut contains many other functional compounds like proteins, fibers, polyphenols, antioxidants, vitamins and minerals which can be added as a functional ingredient into many processed foods. Recently it has also revealed that peanuts are excellent source of compou ...
DOI:
10.1007/s13197-015-2007-9
PubMed:
26787930
PubMed Central:
PMC4711439

4. Identification of activators of methionine sulfoxide reductases A and B

Author:
Cudic, Predrag; Joshi, Neelambari; Sagher, Daphna; Williams, Brandon T.; Stawikowski, Maciej J.; Weissbach, Herbert
Source:
Biochemical and biophysical research communications 2016 v.469 pp. 863-867
ISSN:
0006-291X
Subject:
longevity,   etc   ; Caenorhabditis elegans; Drosophila melanogaster; cattle; enzymes; humans; methionine; proteins; reactive oxygen species; transgenic insects;     Show all 10 Subjects
Abstract:
... The methionine sulfoxide reductase (Msr) family of enzymes has been shown to protect cells against oxidative damage. The two major Msr enzymes, MsrA and MsrB, can repair oxidative damage to proteins due to reactive oxygen species, by reducing the methionine sulfoxide in proteins back to methionine. A role of MsrA in animal aging was first demonstrated in Drosophila melanogaster where transgenic fl ...
DOI:
10.1016/j.bbrc.2015.12.077
PubMed:
26718410
PubMed Central:
PMC4724238

5. Conceptualizing and communicating management effects on forest water quality

Author:
Futter, Martyn N.; Högbom, Lars; Valinia, Salar; Sponseller, Ryan A.; Laudon, Hjalmar
Source:
Ambio 2016 v.45 no.Supplement 2 pp. 188-202
ISSN:
0044-7447
Subject:
longevity,   etc   ; aquatic organisms; atmospheric deposition; boreal forests; forestry; humans; land management; mercury; pollutants; sediments; traffic; water activity; water quality; weathering;     Show all 14 Subjects
Abstract:
... We present a framework for evaluating and communicating effects of human activity on water quality in managed forests. The framework is based on the following processes: atmospheric deposition, weathering, accumulation, recirculation and flux. Impairments to water quality are characterized in terms of their extent, longevity and frequency. Impacts are communicated using a “traffic lights” metaphor ...
DOI:
10.1007/s13280-015-0753-6
PubMed:
26744053
PubMed Central:
PMC4705064

6. Developing an in vivo toxicity assay for RNAi risk assessment in honey bees, Apis mellifera L

Author:
Vélez, Ana María; Jurzenski, Jessica; Matz, Natalie; Zhou, Xuguo; Wang, Haichuan; Ellis, Marion; Siegfried, Blair D.
Source:
Chemosphere 2016 v.144 pp. 1083-1090
ISSN:
0045-6535
Subject:
longevity,   etc   ; Apis mellifera; Diabrotica virgifera virgifera; RNA interference; adults; corn; dietary exposure; double-stranded RNA; eclosion; environmental assessment; gene expression; honey bees; insecticidal properties; larvae; larval development; pollen; risk assessment process; toxicity;     Show all 18 Subjects
Abstract:
... Maize plants expressing dsRNA for the management of Diabrotica virgifera virgifera are likely to be commercially available by the end of this decade. Honey bees, Apis mellifera, can potentially be exposed to pollen from transformed maize expressing dsRNA. Consequently, evaluation of the biological impacts of RNAi in honey bees is a fundamental component for ecological risk assessment. The insectic ...
DOI:
10.1016/j.chemosphere.2015.09.068
Chorus Open Access:
10.1016/j.chemosphere.2015.09.068

7. Fish and fish-liver oil consumption in adolescence and midlife and risk of CHD in older women

Author:
Haraldsdottir, Alfheidur; Torfadottir, Johanna E; Valdimarsdottir, Unnur A; Aspelund, Thor; Harris, Tamara B; Launer, Lenore J; Gudnason, Vilmundur; Steingrimsdottir, Laufey
Source:
Public health nutrition 2016 v.19 no.2 pp. 318-325
ISSN:
1475-2727
Subject:
longevity,   etc   ; adolescence; confidence interval; eating habits; education; fish; fish consumption; models; odds ratio; oils; regression analysis; risk; risk reduction; women;     Show all 14 Subjects
Abstract:
... To study the association of fish and fish-liver oil consumption across the lifespan with CHD later in life among Icelandic women, with special emphasis on the effects of consumption in adolescence. Prevalence association study. Logistic regression was used to estimate odds ratios and 95 % confidence intervals of CHD according to fish or fish-liver oil exposure. Models were adjusted for age, educat ...
DOI:
10.1017/S1368980015001020
PubMed:
25882499
PubMed Central:
PMC5395091

8. Functional diversity of complex I subunits in Candida albicans mitochondria

Author:
Li, Dongmei; She, Xiaodong; Calderone, Richard
Source:
Current genetics 2016 v.62 no.1 pp. 87-95
ISSN:
0172-8083
Subject:
longevity,   etc   ; Candida albicans; antifungal agents; functional diversity; fungi; mammals; mitochondria; mutants; oxidoreductases; pathogenesis; protein subunits; proteins; species diversity; transcription (genetics); virulence;     Show all 15 Subjects
Abstract:
... Our interest in the mitochondria of Candida albicans has progressed to the identification of several proteins that are critical to complex I (CI) activity. We speculated that there should be major functional differences at the protein level between mammalian and fungal mitochondria CI. In our pursuit of this idea, we were helped by published data of CI subunit proteins from a broad diversity of sp ...
DOI:
10.1007/s00294-015-0518-6
PubMed:
26373419
PubMed Central:
PMC4724564

9. Preadult life history variation determines adult transcriptome expression

Author:
Etges, William J.; Oliveira, Cássia; Rajpurohit, Subhash; Gibbs, Allen G.
Source:
Molecular ecology 2016 v.25 no.3 pp. 741-763
ISSN:
0962-1083
Subject:
longevity,   etc   ; Drosophila; adenosine triphosphate; adults; cacti and succulents; chromatin; desert insects; energy; gene expression; gene expression regulation; genes; genetic correlation; glucose; life history; mitochondria; protein synthesis; rearing; reproductive isolation; ribosomes; transcriptome; tricarboxylic acid cycle; Mexico;     Show all 22 Subjects
Abstract:
... Preadult determinants of adult fitness and behaviour have been documented in a variety of organisms with complex life cycles, but little is known about expression patterns of genes underlying these adult traits. We explored the effects of differences in egg‐to‐adult development time on adult transcriptome and cuticular hydrocarbon variation in order to understand the nature of the genetic correlat ...
DOI:
10.1111/mec.13505
PubMed:
26615085
PubMed Central:
PMC4738099

10. Cross-sectional association between serum concentrations of n-3 long-chain PUFA and depressive symptoms: results in Japanese community dwellers

Author:
Horikawa, Chika; Otsuka, Rei; Kato, Yuki; Nishita, Yukiko; Tange, Chikako; Kakutani, Saki; Rogi, Tomohiro; Kawashima, Hiroshi; Shibata, Hiroshi; Ando, Fujiko; Shimokata, Hiroshi
Source:
The British journal of nutrition 2016 v.115 no.4 pp. 672-680
ISSN:
1475-2662
Subject:
longevity,   etc   ; Japanese people; Western diets; blood serum; cross-sectional studies; epidemiological studies; fish consumption; longitudinal studies; men; mental depression; omega-3 fatty acids; omega-6 fatty acids; polyunsaturated fatty acids; regression analysis; women;     Show all 15 Subjects
Abstract:
... The effect of n-3 long-chain PUFA (n-3 LCPUFA) on depression in healthy subjects is unclear, and most of the previous studies have focused on populations eating Western diets with lower fish intake. The present study investigated the association between blood levels of n-3 LCPUFA and depressive symptoms in Japanese community dwellers with higher n-3 LCPUFA blood levels. A cross-sectional study was ...
DOI:
10.1017/S0007114515004754
PubMed:
26689657
PubMed Central:
PMC4762234

11. Genome-wide association and identification of candidate genes for age at puberty in swine

Author:
Nonneman, Dan J.; Schneider, James F.; Lents, Clay A.; Wiedmann, Ralph T.; Vallet, Jeffrey L.; Rohrer, Gary A.
Source:
BMC Genetics 2016 v.17 pp. 50
ISSN:
1471-2156
Subject:
longevity,   etc   ; Bayesian theory; anestrus; boars; estrus; estrus detection; farrowing; genes; genetic markers; genetic variance; genotyping; gilts; herds; loci; marker-assisted selection; menarche; pork; puberty; quantitative trait loci; reproductive efficiency; single nucleotide polymorphism; somatotropin; sows;     Show all 23 Subjects
Abstract:
... Background: Reproductive efficiency has a great impact on the economic success of pork production. Gilts comprise a significant portion of breeding females and gilts that reach puberty earlier tend to stay in the herd longer and be more productive. About 10 to 30 % of gilts never farrow a litter and the most common reasons for removal are anestrus and failure to conceive. Puberty in pigs is usuall ...
Handle:
10113/62001
DOI:
10.1186/s12863-016-0352-y
PubMed:
26923368
PubMed Central:
PMC4770536

12. Mosquito Defense Strategies against Viral Infection

Author:
Cheng, Gong; Liu, Yang; Wang, Penghua; Xiao, Xiaoping
Source:
Trends in parasitology 2016 v.32 no.3 pp. 177-186
ISSN:
1471-4922
Subject:
longevity,   etc   ; Culicidae; arboviruses; chronic diseases; complications (disease); financial economics; immunity; tissues; virus replication;     Show all 9 Subjects
Abstract:
... Mosquito-borne viral diseases are a major concern of global health and result in significant economic losses in many countries. As natural vectors, mosquitoes are very permissive to and allow systemic and persistent arbovirus infection. Intriguingly, persistent viral propagation in mosquito tissues neither results in dramatic pathological sequelae nor impairs the vectorial behavior or lifespan, in ...
DOI:
10.1016/j.pt.2015.09.009
PubMed:
26626596
PubMed Central:
PMC4767563

13. Sex‐specific plasticity and genotype × sex interactions for age and size of maturity in the sheepshead swordtail, Xiphophorus birchmanni

Author:
Boulton, K.; Rosenthal, G. G.; Grimmer, A. J.; Walling, C. A.; Wilson, A. J.
Source:
Journal of evolutionary biology 2016 v.29 no.3 pp. 645-656
ISSN:
1010-061X
Subject:
longevity,   etc   ; Xiphophorus birchmanni; adults; evolutionary adaptation; females; genes; genetic correlation; genotype; males; sex ratio; sexual dimorphism;     Show all 11 Subjects
Abstract:
... Responses to sexually antagonistic selection are thought to be constrained by the shared genetic architecture of homologous male and female traits. Accordingly, adaptive sexual dimorphism depends on mechanisms such as genotype‐by‐sex interaction (G×S) and sex‐specific plasticity to alleviate this constraint. We tested these mechanisms in a population of Xiphophorus birchmanni (sheepshead swordtail ...
DOI:
10.1111/jeb.12814
PubMed:
26688295
PubMed Central:
PMC5102681

14. The calcareous brown alga Padina pavonica in southern Britain: population change and tenacity over 300 years

Author:
Herbert, Roger J. H.; Ma, Lisha; Marston, Anne; Farnham, William F.; Tittley, Ian; Cornes, Richard C.
Source:
Marine biology 2016 v.163 no.3 pp. 46
ISSN:
0025-3162
Subject:
longevity,   etc   ; Padina pavonica; coasts; fronds; interspecific variation; prediction; spores; spring; storms; summer; temperature; England;     Show all 12 Subjects
Abstract:
... Understanding long-term persistence and variability in species populations can help to predict future survival, growth and distribution; however, sustained observations are exceedingly rare. We examine and interpret a remarkable record of the calcareous brown alga Padina pavonica (Phaeophyceae) at its northern limit on the south coast of England (50°N, 1–3°W) from 1680 to 2014, which is probably t ...
DOI:
10.1007/s00227-015-2805-7
PubMed:
26900178
PubMed Central:
PMC4749647

15. The effect of a low iron diet and early life methylmercury exposure in Daphnia pulex

Author:
Hudson, Sherri L.; Doke, Dzigbodi A.; Gohlke, Julia M.
Source:
Food and chemical toxicology 2016 v.89 pp. 112-119
ISSN:
0278-6915
Subject:
longevity,   etc   ; Ankistrodesmus falcatus; Daphnia pulex; algae; culture media; diet; dose response; freshwater; humans; image analysis; iron; long term effects; methylmercury compounds; models; reproduction; risk; staining; toxicology; triacylglycerols;     Show all 19 Subjects
Abstract:
... Iron (Fe) deficiency increases risk for adverse health outcomes in humans; however little is known about the potential interaction with methylmercury (MeHg) exposure. Studies testing multiple stressor hypotheses are expensive and time consuming in mammalian model systems; therefore, determining relevance of alternative models is important. Daphnia pulex were fed standard or low-Fe diets of freshwa ...
DOI:
10.1016/j.fct.2016.01.012
PubMed:
26806633
PubMed Central:
PMC5102066

16. The effects of asymmetric competition on the life history of Trinidadian guppies

Author:
Bassar, Ronald D.; Childs, Dylan Z.; Rees, Mark; Tuljapurkar, Shripad; Reznick, David N.; Coulson, Tim; Heino, Mikko
Source:
Ecology letters 2016 v.19 no.3 pp. 268-278
ISSN:
1461-023X
Subject:
longevity,   etc   ; evolution; life history; models; population dynamics; variance;     Show all 6 Subjects
Abstract:
... The effects of asymmetric interactions on population dynamics has been widely investigated, but there has been little work aimed at understanding how life history parameters like generation time, life expectancy and the variance in lifetime reproductive success are impacted by different types of competition. We develop a new framework for incorporating trait‐mediated density‐dependence into size‐s ...
DOI:
10.1111/ele.12563
PubMed:
26843397
PubMed Central:
PMC4991285

17. The reproductive advantages of a long life: longevity and senescence in wild female African elephants

Author:
Lee, Phyllis C.; Fishlock, Victoria; Webber, C. Elizabeth; Moss, Cynthia J.
Source:
Behavioral ecology and sociobiology 2016 v.70 no.3 pp. 337-345
ISSN:
0340-5443
Subject:
longevity,   etc   ; calves; fecundity; females; mortality; viability; whales; Kenya;     Show all 8 Subjects
Abstract:
... Long-lived species such as elephants, whales and primates exhibit extended post-fertile survival compared to species with shorter lifespans but data on age-related fecundity and survival are limited to few species or populations. We assess relationships between longevity, reproductive onset, reproductive rate and age for 834 longitudinally monitored wild female African elephants in Amboseli, Kenya ...
DOI:
10.1007/s00265-015-2051-5
PubMed:
26900212
PubMed Central:
PMC4748003

18. The Mitochondrial Basis of Aging

Author:
Sun, Nuo; Youle, Richard J.; Finkel, Toren
Source:
Molecular cell 2016 v.61 no.5 pp. 654-666
ISSN:
1097-2765
Subject:
longevity,   etc   ; cell senescence; inflammation; mitochondria; signal transduction; stem cells; unfolded protein response;     Show all 7 Subjects
Abstract:
... A decline in mitochondrial quality and activity has been associated with normal aging and correlated with the development of a wide range of age-related diseases. Here, we review the evidence that a decline in mitochondria function contributes to aging. In particular, we discuss how mitochondria contribute to specific aspects of the aging process, including cellular senescence, chronic inflammatio ...
DOI:
10.1016/j.molcel.2016.01.028
PubMed:
26942670
PubMed Central:
PMC4779179

19. Signaling in Host-Associated Microbial Communities

Author:
Fischbach, Michael A.; Segre, Julia A.
Source:
Cell 2016 v.164 no.6 pp. 1288-1300
ISSN:
0092-8674
Subject:
longevity,   etc   ; humans; microbial communities; microorganisms; models;     Show all 5 Subjects
Abstract:
... Human-associated microbiota form and stabilize communities based on interspecies interactions. We review how these microbe-microbe and microbe-host interactions are communicated to shape communities over a human’s lifespan, including periods of health and disease. Modeling and dissecting signaling in host-associated communities is crucial to understand their function and will open the door to ther ...
DOI:
10.1016/j.cell.2016.02.037
PubMed:
26967294
PubMed Central:
PMC4801507

20. A review of sugar consumption from nationally representative dietary surveys across the world

Author:
Newens, K. J.; Walton, J.
Source:
Journal of human nutrition and dietetics 2016 v.29 no.2 pp. 225-240
ISSN:
0952-3871
Subject:
longevity,   etc   ; adolescents; adults; dietary surveys; eating habits; energy; food intake; fructose; fruit juices; glucose; honey; issues and policy; juice concentrates; lactose; maltose; monitoring; public health; school children; sucrose; syrups;     Show all 20 Subjects
Abstract:
... BACKGROUND: Government and health organisations worldwide have recently reviewed the evidence on the role of dietary sugars in relation to health outcomes. Hence, it is timely to review current intakes of dietary sugars with respect to this guidance and as a benchmark for future surveillance. METHODS: This review collates data from nationally representative dietary surveys across the world and rep ...
DOI:
10.1111/jhn.12338
PubMed:
26453428
PubMed Central:
PMC5057348