PubAg

Main content area

You searched for: Subject "viability" Remove constraint Subject: "viability" Publication Year 2016 Remove constraint Publication Year: 2016
Start Over

Search

3,344  Search Results

| 3,301 - 3,344 of 3,344 | Next »
Number of results to display per page

Search Results

3301. Curdlan in fibers as carriers of tetracycline hydrochloride: Controlled release and antibacterial activity

Author:
El-Naggar, Mehrez E.; Abdelgawad, Abdelrahman M.; Salas, Carlos; Rojas, Orlando J.
Source:
Carbohydrate polymers 2016 v.154 pp. 194-203
ISSN:
0144-8617
Subject:
cell viability,   etc   ; Escherichia coli; antibacterial properties; aqueous solutions; crosslinking; curdlan; differential scanning calorimetry; drugs; glutaraldehyde; image analysis; nanofibers; polyethylene glycol; scanning electron microscopy; spectroscopy; surface tension; tetracycline; thermal stability; thermogravimetry; viscosity;     Show all 19 Subjects
Abstract:
... Curdlan (CURD) and polyethylene oxide were used to synthesize nanofibers as carriers of hydro soluble tetracycline hydrochloride (TCH). The viscosity, surface tension and conductivity of the precursor multicomponent aqueous solutions were determined and adjusted to produce defect-free fiber webs. Except for a slight increase in diameter, the addition of TCH did not affect the original morphology o ...
DOI:
10.1016/j.carbpol.2016.08.042

3302. Liposomal prednisolone inhibits tumor growth in a spontaneous mouse mammary carcinoma model

Author:
Deshantri, Anil K.; Kooijmans, Sander A.A.; Kuijpers, Sylvia A.; Coimbra, Maria; Hoeppener, Astrid; Storm, Gert; Fens, Marcel H.A.M.; Schiffelers, Raymond M.
Source:
Journal of Controlled Release 2016 v.243 pp. 243-249
ISSN:
0168-3659
Subject:
cell viability,   etc   ; adrenal cortex hormones; animal models; anti-inflammatory agents; antineoplastic activity; breast neoplasms; etiology; human diseases; humans; inflammation; metastasis; mice; microRNA; nanocarriers; neoplasm cells; phosphates; prednisolone; transgenic animals;     Show all 18 Subjects
Abstract:
... Cancers are abundantly infiltrated by inflammatory cells that are modulated by tumor cells to secrete mediators fostering tumor cell survival and proliferation. Therefore, agents that interfere with inflammatory signaling molecules or specific immune cell populations have been investigated as anticancer drugs.Corticosteroids are highly potent anti-inflammatory drugs, whose activity is intensified ...
DOI:
10.1016/j.jconrel.2016.10.016

3303. Effects of silver nanoparticles of different sizes on cytotoxicity and oxygen metabolism disorders in both reproductive and respiratory system cells

Author:
Zapór, Lidia
Source:
Archives of environmental protection 2016 v.42 no.4 pp. 32-47
ISSN:
2083-4810
Subject:
cell viability,   etc   ; DNA damage; anti-infective agents; cell membranes; cytotoxicity; industry; lipid peroxidation; metabolism; mitochondria; nanosilver; oxygen; particle size; reactive oxygen species; respiratory system; risk;     Show all 15 Subjects
Abstract:
... Silver nanoparticles (AgNPs) are widely used in numerous industries and areas of daily life, mainly as antimicrobial agents. The particles size is very important, but still not suffi ciently recognized parameter infl uencing the toxicity of nanosilver. The aim of this study was to investigate the cytotoxic effects of AgNPs with different particle size (~ 10, 40 and 100 nm). The study was conducted ...
DOI:
10.1515/aep-2016-0038

3304. Ankaflavin and Monascin Induce Apoptosis in Activated Hepatic Stellate Cells through Suppression of the Akt/NF-κB/p38 Signaling Pathway

Author:
Cheng, Chih-Fu; Pan, Tzu-Ming
Source:
Journal of agricultural and food chemistry 2016 v.64 no.49 pp. 9326-9334
ISSN:
1520-5118
Subject:
cell viability,   etc   ; ankaflavin; apoptosis; caspase-3; cell growth; cyclins; extracellular matrix; fibrosis; interphase; liver cirrhosis; metabolites; mitogen-activated protein kinase; signal transduction;     Show all 13 Subjects
Abstract:
... The increased proliferation of activated hepatic stellate cells (HSCs) is associated with hepatic fibrosis and excessive extracellular matrix (ECM)-protein production. We examined the inhibitory effects of the Monascus purpureus-fermented metabolites, ankaflavin and monascin (15 and 30 μM), on the Akt/nuclear factor (NF)-κB and p38 mitogen-activated protein kinase (MAPK) signaling pathways in HSC- ...
DOI:
10.1021/acs.jafc.6b03700

3305. Development of backcross generations and new interspecific hybrid combinations for introgression breeding in eggplant (Solanum melongena)

Author:
Kouassi, Brice; Prohens, Jaime; Gramazio, Pietro; Kouassi, Abou B.; Vilanova, Santiago; Galán-Ávila, Alberto; Herraiz, Francisco J.; Kouassi, Auguste; Seguí-Simarro, Jose M.; Plazas, Mariola
Source:
Scientia horticulturae 2016 v.213 pp. 199-207
ISSN:
0304-4238
Subject:
viability,   etc   ; Solanum melongena; backcrossing; eggplants; gene pool; genetic background; genetic improvement; hybrids; interspecific hybridization; introgression; ovule culture; parents; pollen; wild relatives;     Show all 14 Subjects
Abstract:
... Introgression breeding can contribute to broadening the genetic background of eggplant (Solanum melongena). We used six eggplant varieties and 44 interspecific hybrids between these eggplant accessions and 10 accessions of wild relatives from the primary genepool species S. insanum and secondary genepool species S. anguivi, S. dasyphyllum, S. incanum, S. lichtensteinii, and S. tomentosum to obtain ...
DOI:
10.1016/j.scienta.2016.10.039

3306. Dopamine Modified Organic–Inorganic Hybrid Coating for Antimicrobial and Osteogenesis

Author:
Li, Man; Liu, Xiangmei; Xu, Ziqiang; Yeung, K.W.K.; Wu, Shuilin
Source:
ACS applied materials 2016 v.8 no.49 pp. 33972-33981
ISSN:
1944-8252
Subject:
cell viability,   etc   ; Escherichia coli; chitosan; coatings; cytotoxicity; hydroxyapatite; nanosilver; silver; ultraviolet radiation;     Show all 9 Subjects
Abstract:
... A hybrid coating composed of hydroxyapatite (HA), Ag nanoparticles (NPs), and chitosan (CS) was successfully prepared on a Ti substrate by a layer-by-layer assembly process. A polydopamine-assisted (PDA-assisted) coating showed a good bond with HA. Ag NPs were uniformly distributed into the hybrid coating through a solution method and ultraviolet light reduction. A CS nanofilm was deposited via sp ...
DOI:
10.1021/acsami.6b09457

3307. Gemcitabine and Antisense-microRNA Co-encapsulated PLGA–PEG Polymer Nanoparticles for Hepatocellular Carcinoma Therapy

Author:
Devulapally, Rammohan; Foygel, Kira; Sekar, Thillai V; Willmann, Juergen K.; Paulmurugan, Ramasamy
Source:
ACS Applied Materials & Interfaces 2016 v.8 no.49 pp. 33412-33422
ISSN:
1944-8252
Subject:
cell viability,   etc   ; antineoplastic agents; apoptosis; cell cycle checkpoints; cell proliferation; cytotoxicity; drug delivery systems; drug resistance; drug therapy; emulsions; encapsulation; flow cytometry; hepatoma; humans; nanoparticles; permeability; polymers;     Show all 17 Subjects
Abstract:
... Hepatocellular carcinoma (HCC) is highly prevalent, and the third most common cause of cancer-associated deaths worldwide. HCC tumors respond poorly to chemotherapeutic anticancer agents due to inherent and acquired drug resistance, and low drug permeability. Targeted drug delivery systems with significant improvement in therapeutic efficiency are needed for successful HCC therapy. Here, we report ...
DOI:
10.1021/acsami.6b08153

3308. Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission

Author:
Wu, Haili; Wang, Yingying; Wu, Changxin; Yang, Peng; Li, Hanqing; Li, Zhuoyu
Source:
Journal of agricultural and food chemistry 2016 v.64 no.49 pp. 9356-9367
ISSN:
1520-5118
Subject:
cell viability,   etc   ; antineoplastic activity; antineoplastic agents; apoptosis; cell proliferation; inhibitory concentration 50; mitochondria; neoplasm cells; neoplasms; phytoalexins; proteins; pyruvate kinase; quantitative analysis; resveratrol;     Show all 14 Subjects
Abstract:
... Resveratrol (Res), a natural phytoalexin found in a variety of plants, has significant antitumor activity. Pyruvate kinase M2 (PKM2) has abnormally high expression in various tumor cells, and it has been implicated in the survival of tumors. However, whether and how Res inhibits PKM2 expression is poorly understood. In the present study, we found that treatment with Res inhibited cell proliferatio ...
DOI:
10.1021/acs.jafc.6b04549

3309. Synthetic lipopeptides as potential topical therapeutics in wound and skin care: in vitro studies of permeation and skin cells behaviour

Author:
Kukowska, Monika; Pikuła, Michał; Kukowska-Kaszuba, Magdalena; Schumacher, Adriana; Dzierzbicka, Krystyna; Trzonkowski, Piotr
Source:
RSC advances 2016 v.6 no.116 pp. 115120-115131
ISSN:
2046-2069
Subject:
viability,   etc   ; antimicrobial properties; bacteria; cell movement; cell proliferation; cell senescence; collagen; collagenase; diffusivity; enzyme activity; fibroblasts; in vitro studies; keratinocytes; lipopeptides; lipophilicity; models; oxidative stress; permeability; reversed-phase high performance liquid chromatography; skin (animal); skin lesions; staining; therapeutics; tissue repair; ultraviolet-visible spectroscopy;     Show all 25 Subjects
Abstract:
... Wound healing is an extraordinarily complicated process associating with the cell aging, slowing down of cell renewal mechanism and even loss of protective function to environmentally induced oxidative stress. A lack of effective treatment results in the appearance of skin lesions and chronic wounds. A satisfactory answer to skin care and therapy problems seems to be a molecule Gly-His-Lys of natu ...
DOI:
10.1039/c6ra24424f

3310. Cardioprotective effects of monocyte locomotion inhibitory factor on myocardial ischemic injury by targeting vimentin

Author:
Jiang, Shu; Liu, Yulan; Wang, Jing; Zhang, Yue; Rui, Yaocheng; Zhang, Yuefan; Li, Tiejun
Source:
Life sciences 2016 v.167 pp. 85-91
ISSN:
0024-3205
Subject:
cell viability,   etc   ; Entamoeba histolytica; Western blotting; apoptosis; binding proteins; blood serum; cardioprotective effect; caspase-3; creatine kinase; flow cytometry; heart; heat stability; in vitro studies; infarction; inflammation; lactate dehydrogenase; locomotion; mice; mitogen-activated protein kinase; models; monocytes; myocardial ischemia; small interfering RNA; staining; stroke; troponin I; vimentin;     Show all 27 Subjects
Abstract:
... Monocyte locomotion inhibitory factor (MLIF), a heat-stable pentapeptide produced by Entamoeba histolytica, has anti-inflammatory function and protective effect on ischemic stroke. In this study, we evaluated the effect of MLIF on myocardial ischemia. Mice were subjected to ischemia/reperfusion by occlusion of the left anterior descending artery (LAD). After sacrifice, the serum concentrations of ...
DOI:
10.1016/j.lfs.2016.10.021

3311. Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects

Author:
Tang, Qin; Ji, Fangling; Sun, Wenhui; Wang, Jingyun; Guo, Jianli; Guo, Lianying; Li, Yachen; Bao, Yongming
Source:
Phytomedicine 2016 v.23 no.14 pp. 1778-1786
ISSN:
0944-7113
Subject:
viability,   etc   ; DNA damage; DNA topoisomerase; Scutellaria baicalensis; Western blotting; alkaloids; antineoplastic activity; apoptosis; catalytic activity; cell cycle checkpoints; drug therapy; drugs; flavonoids; flow cytometry; in vivo studies; mice; neoplasms; plasmids;     Show all 18 Subjects
Abstract:
... 10-Hydroxy camptothecin (HCPT), a naturally occurring alkaloid, is a clinical drug for cancer chemotherapy. Baicalein (BA) is a flavonoid extracted from the root of Scutellaria baicalensis. The synergistic anti-cancer effect of BA and HCPT has not been reported.To explore whether and how BA enhances the anti-cancer effect of HCPT in BGC823 cells.Cell viability was measured by MTT assay. Apoptosis ...
DOI:
10.1016/j.phymed.2016.10.018

3312. Environmental pollution and shipping feasibility of the Nicaragua Canal

Author:
Chen, Jihong; Zeng, Xin; Deng, Yibing
Source:
Marine pollution bulletin 2016 v.113 no.1-2 pp. 87-93
ISSN:
0025-326X
Subject:
viability,   etc   ; canals (waterways); decision making; economic costs; environmental impact; industry; risk; shipping; stakeholders; water pollution; Nicaragua; Panama;     Show all 12 Subjects
Abstract:
... In recent years, the Nicaraguan government's renewed interest in constructing this interoceanic canal has once again aroused widespread concern, particularly in the global shipping industry. The project's immense ecological risks, coupled with the recent expansions of both the Panama Canal and the Suez Canal, have raised questions among scientists and experts about its viability. Whether the Nicar ...
DOI:
10.1016/j.marpolbul.2016.08.074

3313. HPLC-based metabolomics to identify cytotoxic compounds from Plectranthus amboinicus (Lour.) Spreng against human breast cancer MCF-7Cells B Analytical technologies in the biomedical and life sciences

Author:
Yulianto, Wahid; Andarwulan, Nuri; Giriwono, Puspo Edi; Pamungkas, Joko
Source:
Journal of chromatography 2016 v.1039 pp. 28-34
ISSN:
1570-0232
Subject:
viability,   etc   ; Plectranthus amboinicus; active ingredients; breast neoplasms; chloroform; cytotoxicity; diterpenoids; ethanol; ethyl acetate; hexane; high performance liquid chromatography; humans; inhibitory concentration 50; metabolomics; plant extracts; wavelengths;     Show all 16 Subjects
Abstract:
... The objective of this study was to identify the active compounds in Plectranthus amboinicus (Lour.) Spreng which play a role to inhibit viability of breast cancer MCF-7 cells using HPLC-based metabolomics approach. Five fractions of the plant extract were observed including ethanol, hexane, chloroform, ethyl acetate and water fraction. There were 45 HPLC chromatograms resulted from 5 fractions wit ...
DOI:
10.1016/j.jchromb.2016.10.024

3314. Optimization of the formation of embedded multicellular spheroids of MCF-7 cells: How to reliably produce a biomimetic 3D model

Author:
Zhang, Wenli; Li, Caibin; Baguley, Bruce C.; Zhou, Fang; Zhou, Weisai; Shaw, John P.; Wang, Zhen; Wu, Zimei; Liu, Jianping
Source:
Analytical biochemistry 2016 v.515 pp. 47-54
ISSN:
0003-2697
Subject:
viability,   etc   ; biomimetics; cell suspension culture; centrifugation; collagen; culture media; cytotoxicity; doxorubicin; harvesting; methylcellulose; models; neoplasms; propidium; staining; viscosity;     Show all 15 Subjects
Abstract:
... To obtain a multicellular MCF-7 spheroid model to mimic the three-dimensional (3D) of tumors, the microwell liquid overlay (A) and hanging-drop/agar (B) methods were first compared for their technical parameters. Then a method for embedding spheroids within collagen was optimized. For method A, centrifugation assisted cells form irregular aggregates but not spheroids. For method B, an extended sed ...
DOI:
10.1016/j.ab.2016.10.004

3315. Persistent organic pollutants and porphyrins biomarkers in penguin faeces from Kopaitic Island and Antarctic Peninsula

Author:
Rudolph, Ignacio; Chiang, Gustavo; Galbán-Malagón, Cristóbal; Mendoza, Rafael; Martinez, Miguel; Gonzalez, Carlos; Becerra, José; Servos, Mark R.; Munkittrick, Kelly R.; Barra, Ricardo
Source:
The Science of the total environment 2016 v.573 pp. 1390-1396
ISSN:
0048-9697
Subject:
viability,   etc   ; Pygoscelis adeliae; biomarkers; diet; feces; foraging; metabolites; molecular weight; nitrogen; penguins; persistent organic pollutants; polychlorinated biphenyls; porphyrins; stable isotopes; volatile compounds; Antarctic region;     Show all 16 Subjects
Abstract:
... Polychlorinated biphenyl (PCB) levels were determined in the faeces of three Antarctic Peninsula penguin species to assess viability as a non-invasive approach for sampling PCBs in Antarctic biota. These determinations were complemented with stable isotope and porphyrins assessments, and together this methodology determined the role of diet and metabolic disruption in penguins. Up to 60% of the co ...
DOI:
10.1016/j.scitotenv.2016.07.091

3316. Protective effects of essential oil of Citrus limon against aspirin-induced toxicity in IEC-6 cells

Author:
Bouzenna, Hafsia; Hfaiedh, Najla; Giroux-Metges, Marie-Agnès; Elfeki, Abdelfattah; Talarmin, Hélène
Source:
Applied Physiology, Nutrition, and Metabolism 2016 v.42 no.5 pp. 479-486
ISSN:
1715-5320
Subject:
cell viability,   etc   ; Citrus limon; acetates; adverse effects; antioxidant activity; aspirin; catalase; cytotoxicity; epithelial cells; essential oils; leaves; limonene; metabolism; nonsteroidal anti-inflammatory agents; nutrition; oils; protective effect; rats; small intestine; superoxide dismutase;     Show all 20 Subjects
Abstract:
... Aspirin, one of the widely used nonsteroidal anti-inflammatory drugs, is the most highly consumed pharmaceutical product in the world. However, it has several side effects in cells. This study was designed to investigate the antioxidative activity and cytoprotective effects of essential oil of Citrus limon (EOC) extracted from leaves against aspirin-induced damages in the rat small intestine epith ...
DOI:
10.1139/apnm-2016-0515

3317. Proteobacteria become predominant during regrowth after water disinfection

Author:
Becerra-Castro, Cristina; Macedo, Gonçalo; Silva, Adrian M.T.; Manaia, Célia M.; Nunes, Olga C.
Source:
The Science of the total environment 2016 v.573 pp. 313-323
ISSN:
0048-9697
Subject:
cell viability,   etc   ; Acinetobacter; Actinobacteria; Bacteroidetes; Pseudomonas; Rheinheimera; ambient temperature; bacteria; bacterial communities; beta-Proteobacteria; cell structures; community structure; disinfection; drinking water; genome; microbiological quality; ozonation; regrowth; surface water; ultraviolet radiation; wastewater; water treatment;     Show all 22 Subjects
Abstract:
... Disinfection processes aim at reducing the number of viable cells through the generation of damages in different cellular structures and molecules. Since disinfection involves unspecific mechanisms, some microbial populations may be selected due to resilience to treatment and/or to high post-treatment fitness. In this study, the bacterial community composition of secondarily treated urban wastewat ...
DOI:
10.1016/j.scitotenv.2016.08.054

3318. Role of Brycinus lateralis (Teleostei: Alestidae) in dispersal and germination of Nymphaea nouchali (Angiospermae: Nymphaeaceae) seeds on a seasonal floodplain of the Okavango Delta, Botswana

Author:
Mmusi, M; Mosepele, K; Murray-Hudson, M; Teketay, D; Horn, M
Source:
African journal of aquatic science 2016 v.41 no.4 pp. 489-494
ISSN:
1727-9364
Subject:
viability,   etc   ; Brycinus; Nymphaea nouchali; digestive system; fish; floodplains; germination; ingestion; population dynamics; seed dispersal; seeds; Botswana;     Show all 12 Subjects
Abstract:
... Seed passage through the gut of vertebrates can be important for seed dispersal, but might influence seed viability. The ability of seeds to germinate after ingestion by seed-eating fish is important for the population dynamics of some plant species, and significant in the evolution of plant–fish interactions. Certain fish in the Okavango Delta, Botswana, are fruit- and seed-eaters and could act a ...
DOI:
10.2989/16085914.2016.1244041

3319. Valorisation of effluents obtained from chemical and enzymatic chitin production of Illex argentinus pen by-products as nutrient supplements for various bacterial fermentations

Author:
Vázquez, José A.; Caprioni, Romain; Nogueira, Margarita; Menduiña, Araceli; Ramos, Patricia; Pérez-Martín, Ricardo I.
Source:
Biochemical engineering journal 2016 v.116 pp. 34-44
ISSN:
1369-703X
Subject:
cell viability,   etc   ; Illex argentinus; byproducts; chitin; dietary supplements; effluents; enzymatic hydrolysis; equations; fermentation; lactic acid bacteria; metabolites; models; nutrient requirements; peptones; profitability; squid;     Show all 16 Subjects
Abstract:
... The industrial production of chitin generates large volumes of protein effluents that need to be handled and depurated before discharge. The current study highlights the suitability of four effluents, derived from the chemical and enzymatic hydrolysis of Illex argentinus pen to produce β-chitin, as peptones for the growth and metabolite production of six bacteria with different nutrient requiremen ...
DOI:
10.1016/j.bej.2015.12.012

3320. Survival and Growth of Probiotic Lactic Acid Bacteria in Refrigerated Pickle Products

Author:
Fan, Sicun; Price, Robert; Pérez-Díaz, Ilenys
Source:
Journal of food science 2017 v.82 no.1 pp. 167-173
ISSN:
0022-1147
Subject:
viability,   etc   ; Lactobacillus casei; Pediococcus; acetic acids; acid tolerance; acidity; brining; cucumbers; dairy products; juices; lactic acid; lactic acid bacteria; microbial growth; pH; pickled vegetables; probiotics; refrigeration; sodium chloride; survival rate;     Show all 19 Subjects
Abstract:
... We examined 10 lactic acid bacteria that have been previously characterized for commercial use as probiotic cultures, mostly for dairy products, including 1 Pediococcus and 9 Lactobacilli. Our objectives were to develop a rapid procedure for determining the long-term survivability of these cultures in acidified vegetable products and to identify suitable cultures for probiotic brined vegetable pro ...
Handle:
10113/5642512
DOI:
10.1111/1750-3841.13579

3321. Physical Characteristics and Reproductive Performance in Aedes (Diptera: Culicidae)

Author:
Dieng, H.; Abang, F.; Ahmad, A.H.; Abd Ghani, I.; Satho, T.; Miake, F.; Ahmad, H.
Source:
Journal of entomological and acarological research 2016 v.48 no.3 pp. 9
ISSN:
2279-7084
Subject:
viability,   etc   ; Aedes aegypti; adults; body size; dengue; egg production; eggs; fecundity; females; hatching; males; reproductive performance; reproductive traits; spermatozoa; sterile insect technique;     Show all 15 Subjects
Abstract:
... Body size is a physical factor of crucial importance underlying important traits of the reproductive dynamics of both sexes in mosquitoes. Most studies on the influence of body size in mating success of dengue vectors addressed sperm transfer to females and did not consider egg production, a prerequisite for population maintenance; male body size impact on reproduction has attracted little researc ...
DOI:
10.4081/jear.2016.5883

3322. Combined bortezomib-based chemotherapy and p53 gene therapy using hollow mesoporous silica nanospheres for p53 mutant non-small cell lung cancer treatment

Author:
Li, Chun; Hu, Junqing; Li, Wenyao; Song, Guosheng; ShenPresent address: Tumor Initiation and Maintenance Program, Sanford Burnham Prebys Medical Discovery Institute, San Diego, CA 92037, USA., Jia
Source:
Biomaterials science 2016 v.5 no.1 pp. 77-88
ISSN:
2047-4849
Subject:
cell viability; viability assays,   etc   ; Western blotting; apoptosis; caspase-3; clinical trials; drug therapy; drugs; gene expression regulation; gene therapy; gene transfer; inhibitory concentration 50; lung neoplasms; mutants; nanospheres; patients; porous media; proteasome inhibitors; quantitative polymerase chain reaction; signal transduction; silica; staining; toxicity; tumor suppressor genes;     Show all 24 Subjects
Abstract:
... Our previous work reported the development of a proteasome inhibitor, bortezomib (BTZ) encapsulated hollow mesoporous silica nanospheres (HMSNs), as a biocompatible and effective drug-delivery system for non-small cell lung cancer (NSCLC) therapy. Then we found that the tumor-suppressing effect of BTZ or HMSNs-BTZ was compromised in p53 null/mutant NSCLC. In fact, clinical studies have shown a ben ...
DOI:
10.1039/c6bm00449k

3323. Development of zinc-halloysite nanotube/minerals substituted hydroxyapatite bilayer coatings on titanium alloy for orthopedic applications A Physicochemical and engineering aspects

Author:
Chozhanathmisra, M.; Ramya, S.; Kavitha, L.; Gopi, D.
Source:
Colloids and surfaces 2016 v.511 pp. 357-365
ISSN:
0927-7757
Subject:
cell viability,   etc   ; Fourier transform infrared spectroscopy; X-ray diffraction; alloys; antibacterial properties; coatings; corrosion; electrochemistry; energy-dispersive X-ray analysis; hydroxyapatite; nanotubes; orthopedics; samarium; scanning electron microscopy; strontium; titanium; transmission electron microscopy;     Show all 17 Subjects
Abstract:
... In the present investigation, the zinc-halloysite nanotubes (Zn-HNT)/strontium (Sr²⁺), samarium (Sm²⁺) substituted hydroxyapatite (M-HA) bilayer coating is obtained on titanium alloy (Ti6Al4V) by electrodeposition and the Zn-HNT/M-HA bilayer coating can be successfully combined to produce the bioactive and corrosion resistance for orthopaedic applications.The existence the of the as-developed Zn-H ...
DOI:
10.1016/j.colsurfa.2016.10.018

3324. Gadolinium hybrid iron oxide nanocomposites for dual T₁- and T₂-weighted MR imaging of cell labeling

Author:
ZengThese authors contributed equally., Yun; Wang, Liqin; Zhou, Zijian; Wang, Xiaoyong; Zhang, Yang; Wang, Junqing; Mi, Peng; Liu, Gang; Zhou, Liming
Source:
Biomaterials science 2016 v.5 no.1 pp. 50-56
ISSN:
2047-4849
Subject:
cell viability,   etc   ; adults; gadolinium; image analysis; magnetic resonance imaging; mesenchymal stromal cells; mice; nanocomposites; stem cells; therapeutics;     Show all 10 Subjects
Abstract:
... Tracking of cells in biological systems is critically important for monitoring disease treatment, such as in stem cell therapy. This report prepared new types of biocompatible gadolinium hybrid iron oxide (GdIO) nanocomposites, which demonstrated high sensitivity for dual T₁- and T₂-weighted magnetic resonance imaging (MRI). The GdIO nanocomposites could efficiently label mesenchymal stem cells (M ...
DOI:
10.1039/c6bm00706f

3325. Highly luminescent and long-term anti-photobleaching Eu(TTA)3(TOP)3 conjugated poly(St-co-DVB-co-NaSS-co-MAA) nanoparticles A Physicochemical and engineering aspects

Author:
Lee, Jae Won; Kim, Do Kyung
Source:
Colloids and surfaces 2016 v.511 pp. 162-171
ISSN:
0927-7757
Subject:
cell viability,   etc   ; cytotoxicity; dissociation; europium; ions; luminescence; nanoparticles; pH; photobleaching; polymers; scanning electron microscopy; sodium;     Show all 12 Subjects
Abstract:
... Highly luminescent and stable against photobleaching for a long period, Eu³⁺ complexes labelled polymer nanoparticles with a quantum yield of 78% are presented. Europium complexes are prepared by chelating Eu³⁺ with 4,4,4-trifluoro-1-(2-Thienyl)-1,3-butanedione (TTA) and trioctylphosphine (TOP). Poly(St-co-DVB-co-NaSS-co-MAA) (St=styrene; DVB=divinylbenzene; NaSS; 4-styrenesulfonic acid sodium sal ...
DOI:
10.1016/j.colsurfa.2016.09.084

3326. Local delivery of doxorubicin through supramolecular peptide amphiphile nanofiber gels

Author:
Cinar, Goksu; Ozdemir, Ayse; Hamsici, Seren; Gunay, Gokhan; Dana, Aykutlu; Tekinay, Ayse B.; Guler, Mustafa O.
Source:
Biomaterials science 2016 v.5 no.1 pp. 67-76
ISSN:
2047-4849
Subject:
viability,   etc   ; apoptosis; biocompatibility; biodegradability; breast neoplasms; cytotoxicity; diffusivity; doxorubicin; drug delivery systems; drug therapy; encapsulation; fluorescence; gels; hydrophilicity; hydrophobicity; nanofibers; peptides; photobleaching; surfactants;     Show all 19 Subjects
Abstract:
... Peptide amphiphiles (PAs) self-assemble into supramolecular nanofiber gels that provide a suitable environment for encapsulation of both hydrophobic and hydrophilic molecules. The PA gels have significant advantages for controlled delivery applications due to their high capacity to retain water, biocompatibility, and biodegradability. In this study, we demonstrate injectable supramolecular PA nano ...
DOI:
10.1039/c6bm00656f

3327. The development of probiotics for women’s health

Author:
Reid, Gregor
Source:
Canadian journal of microbiology 2016 v.63 no.4 pp. 269-277
ISSN:
1480-3275
Subject:
viability,   etc   ; antibiotics; bladder; lactic acid bacteria; probiotics; women;     Show all 6 Subjects
Abstract:
... The idea you could use lactic acid bacteria to treat and prevent recurrence of vaginal infections was ridiculed in the early 1980s. Bacteria were the bad guys to be eradicated by current and emerging antibiotic classes. Thirty years later, probiotic administration of microbes is widespread worldwide, including for vaginal and bladder health in women, and the scientific basis and clinical efficacy ...
DOI:
10.1139/cjm-2016-0733

3328. Using Nanoliposomes To Construct a FRET-Based Ratiometric Fluorescent Probe for Sensing Intracellular pH Values

Author:
Zhang, Yangyang; Li, Shilei; Zhao, Zhenwen
Source:
Analytical chemistry 2016 v.88 no.24 pp. 12380-12385
ISSN:
1520-6882
Subject:
cell viability,   etc   ; biocompatibility; cytotoxicity; fluorescein; fluorescence; inflammation; pH; quantitative analysis;     Show all 8 Subjects
Abstract:
... Nanoliposomes were first used to encapsulate two fluorophores, fluorescein and cresyl violet, to construct a FRET-based ratiometric fluorescent probe, for sensing intracellular pH values. The morphology, stability, interference factors, biocompatibility, and performance were investigated in detail. The fluorophores-encapsulated nanoliposomes (FEN) probe can be uptaken by cells within 30 min, which ...
DOI:
10.1021/acs.analchem.6b03632

3329. A microfluidic-based cell encapsulation platform to achieve high long-term cell viability in photopolymerized PEGNB hydrogel microspheres

Author:
Jiang, Zhongliang; Xia, Bingzhao; McBride, Ralph; Oakey, John
Source:
Journal of materials chemistry B 2016 v.5 no.1 pp. 173-180
ISSN:
2050-7518
Subject:
cell viability,   etc   ; droplets; emulsions; hydrogels; mechanical properties; medicine; microencapsulation; microgels; microparticles; microstructure; oxygen; photochemical reactions; polyethylene glycol; polymerization; tissue engineering; ultraviolet radiation;     Show all 16 Subjects
Abstract:
... Cell encapsulation within photopolymerized polyethylene glycol (PEG)-based hydrogel scaffolds has been demonstrated as a robust strategy for cell delivery, tissue engineering, regenerative medicine, and developing in vitro platforms to study cellular behavior and fate. Strategies to achieve spatial and temporal control over PEG hydrogel mechanical properties, chemical functionalization, and cytoco ...
DOI:
10.1039/c6tb02551j

3330. Interfacing neurons on carbon nanotubes covered with diamond

Author:
Seyock, Silke; Maybeck, Vanessa; Scorsone, Emmanuel; Rousseau, Lionel; Hébert, Clément; Lissorgues, Gaëlle; Bergonzo, Philippe; Offenhäusser, Andreas
Source:
RSC advances 2016 v.7 no.1 pp. 153-160
ISSN:
2046-2069
Subject:
cell viability,   etc   ; carbon nanotubes; cell growth; cell membranes; electrodes; nanocrystals; neurons; scanning electron microscopy;     Show all 8 Subjects
Abstract:
... A recently discovered material, carbon nanotubes covered with diamond (DCNTs) was tested for its suitability in bioelectronics applications. Diamond shows advantages for bioelectronics applications (wide electro chemical window and bioinertness). This study investigates the effect of electrode surface shape (flat or three dimensional) on cell growth and behavior. For comparison, flat nanocrystalli ...
DOI:
10.1039/c6ra20207a

3331. Theoretical and experimental study of the antifreeze protein AFP752, trehalose and dimethyl sulfoxide cryoprotection mechanism: correlation with cryopreserved cell viability

Author:
Kratochvílová, Irena; Golan, Martin; Pomeisl, Karel; Richter, Jan; Sedláková, Silvia; Šebera, Jakub; Mičová, Júlia; Falk, Martin; Falková, Iva; Řeha, David; Elliott, K. Wade; Varga, Krisztina; Follett, Shelby E.; Šimek, Daniel
Source:
RSC advances 2016 v.7 no.1 pp. 352-360
ISSN:
2046-2069
Subject:
cell viability,   etc   ; Raman spectroscopy; X-ray diffraction; antifreeze proteins; cryopreservation; cryoprotectants; crystal structure; differential scanning calorimetry; dimethyl sulfoxide; fibroblasts; freezing; ice; models; molecular dynamics; physicochemical properties; skin (animal); thawing; trehalose;     Show all 18 Subjects
Abstract:
... In this work the physico-chemical properties of selected cryoprotectants (antifreeze protein TrxA-AFP752, trehalose and dimethyl sulfoxide) were correlated with their impact on the constitution of ice and influence on frozen/thawed cell viability. The freezing processes and states of investigated materials solutions were described and explained from a fundamental point of view using ab initio mode ...
DOI:
10.1039/c6ra25095e

3332. Akt activation by Evodiae Fructus extract protects ovary against 4-vinylcyclohexene diepoxide-induced ovotoxicity

Author:
Nam, Eun-Young; Kim, Sun Ah; Kim, Heejung; Kim, Su-Hyun; Han, Jae-Hyun; Lee, Ju-Hee; Kim, Dong-Il
Source:
Journal of ethnopharmacology 2016 v.194 pp. 733-739
ISSN:
0378-8741
Subject:
cell viability,   etc   ; Chinese hamsters; Euodia; apoptosis; boiling; cytotoxicity; dose response; environmental factors; granulosa cells; herbal medicines; high performance liquid chromatography; humans; mechanism of action; menstruation; protective effect; screening; traditional medicine; water quality; Korean Peninsula;     Show all 19 Subjects
Abstract:
... Evodiae Fructus (EF) is the dried, unripe fruit of Evodia rutaecarpa Benth., and one of the main components of traditional herbal prescriptions issued for the treatment of sterility caused by irregular menstruation in Korea. However, scientific evidence regarding the efficacy and action mechanism of EF is lacking.In this study, the authors established an in vitro screening tool to identify promisi ...
DOI:
10.1016/j.jep.2016.10.048

3333. Bufalin inhibits gefitinib resistant NCI-H460 human lung cancer cell migration and invasion in vitro

Author:
Huang, An-Cheng; Yang, Mei-Due; Hsiao, Yung-Ting; Lin, Tzu-Shun; Ma, Yi-Shih; Peng, Shu-Fen; Hsia, Te-Chun; Cheng, Yih-Dih; Kuo, Chao-Lin; Chung, Jing-Gung
Source:
Journal of ethnopharmacology 2016 v.194 pp. 1043-1050
ISSN:
0378-8741
Subject:
cell viability,   etc   ; Western blotting; adhesion; antineoplastic agents; bioactive properties; cadherins; cell movement; flow cytometry; frogs; humans; lung neoplasms; mitogen-activated protein kinase; neoplasm cells; nitroprusside; non-specific protein-tyrosine kinase; patients; tissue repair; traditional medicine;     Show all 18 Subjects
Abstract:
... Bufalin, a component of Chan Su (frog), has been shown to have biological activities including anti-tumor effects. Gefitinib has been used as an anti-cancer drug in lung cancer patients; however, some patients eventually become gefitinib resistant.In this study, we investigated anti-metastasis effects of bufalin in gefitinib resistant NCI-H460 lung cancer cells.The effects of the bufalin in gefiti ...
DOI:
10.1016/j.jep.2016.11.004

3334. Chinese herbal medicine Fuzheng Kang-Ai decoction sensitized the effect of gefitinib on inhibition of human lung cancer cells through inactivating PI3-K/Akt -mediated suppressing MUC1 expression

Author:
Li, Longmei; Wang, SuMei; Zheng, Fang; Wu, WanYin; Hann, Swei Sunny
Source:
Journal of ethnopharmacology 2016 v.194 pp. 918-929
ISSN:
0378-8741
Subject:
viability,   etc   ; Western blotting; adjuvants; bioluminescence; cell growth; flow cytometry; gene overexpression; growth retardation; herbal medicines; humans; image analysis; in vivo studies; interphase; lung neoplasms; messenger RNA; neoplasm cells; patients; protein phosphorylation; protein synthesis; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; signal transduction; synergism; traditional medicine; transfection;     Show all 25 Subjects
Abstract:
... Chinese herbal medicine (CHM) Fuzheng Kang-Ai (FZKA for short) decoction has been used as adjuvant treatment strategies in lung cancer patients for decades. However, the molecular mechanism underlying the therapeutic potential especially in sensitizing the effect of EGFR-TKI gefitinib has not been well elucidated.Cell viability was detected by MTT assay. Cell cycle distribution was detected by flo ...
DOI:
10.1016/j.jep.2016.10.077

3335. Cudraticusxanthone A isolated from the roots of Cudrania tricuspidata inhibits metastasis and induces apoptosis in breast cancer cells

Author:
Jeon, Soo-Myeong; Lee, Dong-Sung; Jeong, Gil-Saeong
Source:
Journal of ethnopharmacology 2016 v.194 pp. 57-62
ISSN:
0378-8741
Subject:
viability,   etc   ; IKappaB kinase; Maclura tricuspidata; amine oxidase (flavin-containing); antineoplastic activity; apoptosis; breast neoplasms; cell movement; ethanol; flavonoids; flow cytometry; fractionation; gelatinase B; humans; metastasis; minerals; neoplasm cells; phosphorylation; roots; traditional medicine; trees; vitamin B complex; xanthone; China; Japan; Korean Peninsula;     Show all 26 Subjects
Abstract:
... The roots of Cudrania tricuspidata is a deciduous tree found in Korea, China, and Japan. C. tricuspidata contains an abundance of various minerals, B vitamins, and flavonoids to help prevent diverse cancers. Cudratricusxanthone A (CTXA), a compound isolated from the roots of C. tricuspidata, has potent anti-proliferative, antioxidative, and monoamine oxidase inhibitory effects.In the present study ...
DOI:
10.1016/j.jep.2016.08.042

3336. Ginsenoside 20(S)-Rh2 exerts anti-cancer activity through targeting IL-6-induced JAK2/STAT3 pathway in human colorectal cancer cells

Author:
Han, Songhee; Jeong, Ae Jin; Yang, Heejung; Bin Kang, Kyo; Lee, Haeri; Yi, Eun Hee; Kim, Byung-Hak; Cho, Chung-Hyun; Chung, Jin Woong; Sung, Sang Hyun; Ye, Sang-Kyu
Source:
Journal of ethnopharmacology 2016 v.194 pp. 83-90
ISSN:
0378-8741
Subject:
cell viability,   etc   ; drug therapy; metalloproteinases; ginsenosides; medicinal plants; signal transduction; Western blotting; metastasis; neoplasm cells; obesity; phosphorylation; roots; transactivators; stereochemistry; traditional medicine; humans; cytotoxicity; antineoplastic activity; diabetes; colorectal neoplasms; doxorubicin; quantitative polymerase chain reaction; cardiovascular diseases; interleukin-6; Panax ginseng; death; Korean Peninsula; China;     Show all 28 Subjects
Abstract:
... Panax ginseng is one of the most well-known medicinal herbs in Korea and China, which has been used for treatment and prevention of cancer, obesity, diabetes, and cardiovascular diseases. Ginsenosides are the major components of P. ginseng, having a wide range of pharmacological activities. Among the ginsenosides, protopanaxadiol (PPD)-types reportedly have potent anti-cancer effects. Rh2 is PPD-t ...
DOI:
10.1016/j.jep.2016.08.039

3337. Identification of NF-κB inhibitors following Shenfu injection and bioactivity-integrated UPLC/Q-TOF-MS and screening for related anti-inflammatory targets in vitro and in silico

Author:
Li, Pan; Lv, Bin; Jiang, Xiaoqing; Wang, Ting; Ma, Xianghui; Chang, Nianwei; Wang, Xiaoying; Gao, Xiumei
Source:
Journal of ethnopharmacology 2016 v.194 pp. 658-667
ISSN:
0378-8741
Subject:
cell viability,   etc   ; Food and Drug Administration; active ingredients; alkaloids; anti-inflammatory activity; coronary disease; endothelial cells; ginsenosides; inflammation; interleukin-6; screening; signal transduction; stroke; traditional medicine; transcription factor NF-kappa B; China;     Show all 16 Subjects
Abstract:
... Shenfu injection (SFI) is a commercial medicinal product approved by the China Food and Drug Administration that is widely used in the treatment of stroke and coronary heart disease. However, the material basis and the mechanism of SFI are not fully understood.With network pharmacology analysis, our research committed to identify the anti-inflammatory ingredients and mechanism of SFI by combining ...
DOI:
10.1016/j.jep.2016.10.052

3338. (3′R)-hydroxytabernaelegantine C: A bisindole alkaloid with potent apoptosis inducing activity in colon (HCT116, SW620) and liver (HepG2) cancer cells

Author:
Paterna, Angela; Gomes, Sofia E.; Borralho, Pedro M.; Mulhovo, Silva; Rodrigues, Cecília M.P.; Ferreira, Maria-José U.
Source:
Journal of ethnopharmacology 2016 v.194 pp. 236-244
ISSN:
0378-8741
Subject:
cell viability,   etc   ; NAD ADP-ribosyltransferase; Tabernaemontana; alkaloids; apoptosis; colon; colorectal neoplasms; cytotoxicity; fibroblasts; flow cytometry; fluorouracil; fractionation; guavas; human cell lines; humans; inhibitory concentration 50; lactate dehydrogenase; liver; medicinal plants; methanol; neoplasm cells; nuclear magnetic resonance spectroscopy; pro-apoptotic proteins; roots; staining; traditional medicine; Africa;     Show all 27 Subjects
Abstract:
... Tabernaemontana elegans Stapf. (Apocynaceae) is a medicinal plant traditionally used in African countries to treat cancer.To discover new apoptosis inducing lead compounds from T. elegans and provide scientific validation of the ethnopharmacological use of this plant.Through fractionation, (3′R)-hydroxytaberanelegantine C (1), a vobasinyl-iboga bisindole alkaloid, was isolated from a cytotoxic alk ...
DOI:
10.1016/j.jep.2016.09.020

3339. Ziziphora tenuior L. essential oil from Dana Biosphere Reserve (Southern Jordan); Chemical characterization and assessment of biological activities

Author:
Abu-Darwish, M.S.; Cabral, C.; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Paoli, M.; Tomi, F.; Efferth, T.; Salgueiro, L.
Source:
Journal of ethnopharmacology 2016 v.194 pp. 963-970
ISSN:
0378-8741
Subject:
cell viability,   etc   ; Aspergillus; Candida albicans; Cryptococcus neoformans; Ziziphora tenuior; anti-inflammatory activity; antifungal properties; antiseptics; biofilm; biological assessment; biomass; chemical composition; conservation areas; cough; dysentery; essential oils; fever; gas chromatography-mass spectrometry; germ tube; health services; hepatocytes; hydrodistillation; inflammation; keratinocytes; keratinophilic fungi; macrophages; medicinal plants; mice; monoterpenoids; nitric oxide; nuclear magnetic resonance spectroscopy; oils; product development; stomach; tissue repair; toxicity; traditional medicine; uterus; yeasts; Jordan;     Show all 40 Subjects
Abstract:
... Ziziphora tenuior L. (Lamiaceae) is a medicinal plant in Jordan, which is included in various antimicrobial, antiseptic, expectorant and wound healing preparations. It is used for the treatment of cough, stomach ache, dysentery, fever, uterus infection, gut inflammation and painful menstruation.The aim of this study was to assess, for the first time, the chemical composition of the essential oil o ...
DOI:
10.1016/j.jep.2016.10.076

3340. The direct action of hyaluronic acid on human U-937 and HL-60 cells – modification of native and model membranes

Author:
Barbasz, Anna; Kreczmer, Barbara; Dyba, Barbara; Filek, Maria; Rudolphi-Skórska, Elżbieta
Source:
Biologia 2016 v.71 no.11 pp. 1304-1314
ISSN:
1336-9563
Subject:
cell viability,   etc   ; cytotoxicity; granulocytes; humans; hyaluronic acid; lipids; macrophages; molecular weight; receptors;     Show all 9 Subjects
Abstract:
... The aim of the study was to investigate the effect of application of exogenous hyaluronic acid (HA) of various molecular weights on the cells of human immune system. Two cell lines HL-60 and U-937 with various ability to differentiation were chosen. HL-60 cells were differentiated to macrophages and granulocytes, whereas U-937 only to macrophages. For all investigated cell systems the most cytotox ...
DOI:
10.1515/biolog-2016-0157

3341. Effective Cell and Particle Sorting and Separation in Screen-Printed Continuous-Flow Microfluidic Devices with 3D Sidewall Electrodes

Author:
Lin, Xiaoguang; Yao, Jie; Dong, Hua; Cao, Xiaodong
Source:
Industrial & Engineering Chemistry Research 2016 v.55 no.51 pp. 13085-13093
ISSN:
1520-5045
Subject:
cell viability,   etc   ; chemistry; dielectrophoresis; electrodes; erythrocytes; exposure duration; hemolysis; manufacturing; microparticles; polystyrenes;     Show all 10 Subjects
Abstract:
... In recent years, microfluidic dielectrophoresis (DEP) devices, as one of the most promising tools for cell and particle sorting and separation, are facing the bottleneck in the development of practical products due to the high-cost yet low-yield device manufacturing via traditional microelectromechanical systems (MEMS) and the challenge of maintaining the cell viability during DEP treatment. In th ...
DOI:
10.1021/acs.iecr.6b03249

3342. Initiation and development of Erysiphe necator chasmothecia and their role in the epidemiology of grapevine powdery mildew in southern Syria

Author:
Alimad, Nujoud; Naffaa, Walid; Azmeh, Fawaz
Source:
Acta mycologica 2016 v.51 no.2 pp. am.1088
ISSN:
2353-074X
Subject:
viability,   etc   ; Uncinula necator; Vitis; asci; ascospores; bark; branches; epidemiology; fungi; inoculum; leaves; microscopy; powdery mildew; spring; surveys; vineyards; Syria;     Show all 17 Subjects
Abstract:
... Powdery mildew caused by Erysiphe necator is the most important fungal disease of grapevine in southern Syria. The purpose of this study was to determine the development of chasmothecia and their role as a primary inoculum in spring. Leaves and/or branches were examined by a stereo binocular from July to December 2014 and 2015. The number of chasmothecia was estimated on both surfaces of the leave ...
DOI:
10.5586/am.1088

3343. Synthesis, characterization and evaluation of in vitro toxicity in hepatocytes of linear polyesters with varied aromatic and aliphatic co-monomers

Author:
Kakde, Deepak; Powell, Leagh G.; Bansal, Kuldeep K.; Howdle, Steve; Irvine, Derek; Mantovani, Giuseppe; Millar, Gavin; Dailey, Lea Ann; Stone, Vicki; Johnston, Helinor J.; Alexander, Cameron
Source:
Journal of controlled release 2016 v.244 pp. 214-228
ISSN:
0168-3659
Subject:
cell viability,   etc   ; DNA damage; biodegradation; carboxylic ester hydrolases; cell lines; coatings; drug delivery systems; drugs; encapsulation; hepatocytes; models; molecular weight; nanoparticles; oxidants; phosphates; polyesters; succinic acid; toxicity;     Show all 18 Subjects
Abstract:
... Polyesters are extensively used in drug delivery because of their controllable biodegradation properties and perceived favorable cytocompatibility. However, new ester-based materials are continually being sought which can be produced from readily accessible monomers, which can be tuned for drug encapsulation and which retain good cellular compatibilities. In this study, 5 polyesters of similar mol ...
DOI:
10.1016/j.jconrel.2016.08.003

3344. Using Analytic Network Process and Dominance-based Rough Set Approach for sustainable requalification of traditional farm buildings in Southern Italy

Author:
Ottomano Palmisano, Giovanni; Loisi, Rosa V.; Ruggiero, Giuseppe; Rocchi, Lucia; Boggia, Antonio; Roma, Rocco; Dal Sasso, Pasquale
Source:
Land use policy 2016 v.59 pp. 95-110
ISSN:
0264-8377
Subject:
viability,   etc   ; Common Agricultural Policy; agricultural products; attitudes and opinions; employment; environmental education; farm buildings; geographic information systems; issues and policy; multi-criteria decision making; planning; rural areas; rural development; stakeholders; sustainable development; tourism; traditions; villages; Italy;     Show all 19 Subjects
Abstract:
... Rural Sustainable Development (RSD) is promoted by the European Union (EU) Common Agricultural Policy (CAP) 2014–2020, and in particular by the national and regional Rural Development Programmes (RDPs), which are mainly supported by the European Agricultural Fund for Rural Development (EAFRD). At the sub-regional level, a part of the EAFRD is managed by Local Action Groups (LAGs), which decide how ...
DOI:
10.1016/j.landusepol.2016.08.016