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- Zahari, Zuriati, et al. Show all 5 Authors
- Experimental parasitology 2016 v.162 pp. 49-56
- African trypanosomiasis; Trypanosoma rhodesiense; automation; cost effectiveness; dimethyl sulfoxide; drugs; fluorescence; humans; liquids; screening
- ... To accelerate the discovery of novel leads for the treatment of Human African Trypanosomiasis (HAT), it is necessary to have a simple, robust and cost-effective assay to identify positive hits by high throughput whole cell screening. Most of the fluorescence assay was made in black plate however in this study the HTS assay developed in 384-well format using clear plate and black plate, for compari ...
- Vinarov, Zahari, et al. Show all 6 Authors
- Food & function 2016 v.7 no.1 pp. 151-163
- bioavailability; blood serum; calcium; cholesterol; diet; fatty acids; free fatty acids; humans; in vitro digestion; ions; lipophilicity; liver; micelles; models; monoacylglycerols; oils; small intestine; solubilization
- ... Studies in humans show that a calcium-enriched diet leads to lower cholesterol in blood serum. This phenomenon is usually explained in the literature with a reduced cholesterol absorption in the small intestine. Our study aims to clarify the effect of calcium on the solubilisation of cholesterol and fatty acid in the dietary mixed micelles (DMM), viz. on the bioaccessibility of these lipophilic su ...