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1. A comparison of the physiological responses, behaviour and biotransformation of paralytic shellfish poisoning toxins in a surf-clam (Paphies donacina) and the green-lipped mussel (Perna canaliculus)

Author:
Marsden, Islay D.; Contreras, Andrea M.; MacKenzie, Lincoln; Munro, Murray H.G.
Source:
Marine & freshwater research 2016 v.67 no.8 pp. 1163-1174
ISSN:
1323-1650
Subject:
toxins,   etc   ; Alexandrium; Perna canaliculus; algae; algal blooms; biotransformation; clams; humans; monitoring; mussels; paralytic shellfish poisoning; physiological response; poisoning; risk; shellfish; tissues; toxicity;     Show all 17 Subjects
Abstract:
... The accumulation of paralytic shellfish toxins (PSTs) in bivalves is species specific. We compared the physiological responses and the toxin profiles in tissues of the burrowing surf clam, Paphies donacina, and the green-lipped mussel, Perna canaliculus, exposed to the toxic dinoflagellate Alexandrium tamarense. Bivalves were supplied with the toxic algae for 10 days, then allowed a detoxification ...
DOI:
10.1071/MF14374

2. Cryobiology: principles, species conservation and benefits for coral reefs

Author:
Hagedorn, Mary; Carter, Virginia L.
Source:
Reproduction, fertility, and development 2016 v.28 no.8 pp. 1049-1060
ISSN:
1031-3613
Subject:
toxins,   etc   ; asexual reproduction; climate change; coral reefs; corals; cryopreservation; ecosystems; ex situ conservation; extinction; genetic variation; hermaphroditism; in vitro fertilization; oceans; parthenogenesis; spermatozoa; symbionts;     Show all 16 Subjects
Abstract:
... Coral reefs are some of the oldest, most diverse and valuable ecosystems on Earth because they can support one-quarter of all marine life in our oceans. Despite their importance, the world’s coral reefs continue to be degraded at unprecedented rates by local and global threats that are warming and creating a more acidic ocean. This paper explores the reproductive challenges of coral for ex situ co ...
DOI:
10.1071/RD16082

3. Development and validation of ultra-high-performance liquid chromatography–tandem mass spectrometry methods for the simultaneous determination of beauvericin, enniatins (A, A1, B, B1) and cereulide in maize, wheat, pasta and rice A

Author:
Decleer, Marlies; Rajkovic, Andreja; Sas, Benedikt; Madder, Annemieke; De Saeger, Sarah
Source:
Journal of chromatography 2016
ISSN:
0021-9673
Subject:
toxins,   etc   ; corn; detection limit; food matrix; food safety; grain foods; liquid chromatography; pasta; rice; spectrometers; statistical analysis; tandem mass spectrometry; wheat;     Show all 13 Subjects
Abstract:
... Rapid and accurate UPLC–MS/MS methods for the simultaneous determination of beauvericin and the related enniatins (A, A1, B, B1), together with cereulide were successfully developed and validated in cereal and cereal-based food matrices such as wheat, maize, rice and pasta. Although these emerging foodborne toxins are of different microbial origin, the similar structural, toxicological and food sa ...
DOI:
10.1016/j.chroma.2016.10.003

4. Effectiveness of Bt Maize against Corn Rootworm (Coleoptera: Chrysomelidae) and Species Composition in South Dakota Ten Years Following the Introduction of Transgenic Maize1

Author:
Ordosch, David; Narem, Robert; Szczepaniec, Adrianna
Source:
Journal of agricultural and urban entomology 2016 v.32 no.1 pp. 59-70
ISSN:
1523-5475
Subject:
toxins,   etc   ; Bacillus thuringiensis; Diabrotica barberi; Diabrotica virgifera virgifera; bacteria; commercialization; corn; crop production; hybrids; larvae; lodging; long term effects; nutrient uptake; roots; rootworms; species diversity; surveys; transgenic plants; Corn Belt region; South Dakota;     Show all 20 Subjects
Abstract:
... Corn rootworms, Diabrotica spp. (Coleoptera: Chrysomelidae), are the most economically important pest of maize in the United States. The larvae consume maize roots, contributing to poor nutrient uptake, lodging of the plants, and severe yield loss. Transgenic maize expressing toxins from the bacterium Bacillus thuringiensis (Bt) have been employed to combat the pest. However, corn rootworm resista ...
DOI:
10.3954/1523-5475-32.1.59

5. Endophyte metabolites associated with perennial ryegrass toxicosis

Author:
Reed, K. F. M.; Mace, W. J.; Walker, L. V.; Fletcher, L. R.
Source:
Animal production science 2016 v.56 no.5 pp. 895-907
ISSN:
1836-0939
Subject:
toxins,   etc   ; Claviceps purpurea; Lolium perenne; biosynthesis; cultivars; endophytes; ergot; ergotamine; ergovaline; farms; grasses; heat; high performance liquid chromatography; mass spectrometry; metabolites; pastures; poisoning; ruminants; solar radiation; summer; Australia; New Zealand;     Show all 22 Subjects
Abstract:
... Perennial ryegrass (PRG) was analysed for alkaloids associated with the expression of perennial ryegrass endophyte toxicosis (PRGT) in south-east Australia. Over two seasons, the PRG cultivar Samson (‘high endophyte’, viz. naturally infected with a wild-type strain of Epichloë festucae var. lolii) was sampled on five occasions during November to May at four farms in Victoria and at Lincoln, New Ze ...
DOI:
10.1071/AN14495

6. Identification of the immunogenic epitopes of the whole venom component of the Hemiscorpius lepturus scorpion using the Phage display peptide library

Author:
Jahdasani, Roghaye; Jamnani, Fatemeh Rahimi; Behdani, Mahdi; Habibi-Anbouhi, Mahdi; Yardehnavi, Najmeh; Shahbazzadeh, Delavar; Kazemi-Lomedasht, Fatemeh
Source:
Toxicon 2016
ISSN:
0041-0101
Subject:
toxins,   etc   ; Scorpiones; anaphylaxis; antibodies; antiserum; bacteriophages; bioactive compounds; clones; death; epitopes; horses; immunoglobulin G; neutralization; peptide libraries; recombinant vaccines; tropics; venoms;     Show all 17 Subjects
Abstract:
... The venom of the Hemiscorpius lepturus scorpion contains mixtures of bioactive compounds that disturb biochemical and physiological functions of the victims. Hemiscorpius lepturus envenomation is recognized as a serious health concern in tropical regions. So far, there is no preventive procedure, and the main focus is on treatment of victims with an antiserum purified from hyper-immunized horses. ...
DOI:
10.1016/j.toxicon.2016.11.247

7. Sugar and Spice Make Bacteria Not Nice: Protein Glycosylation and Its Influence in Pathogenesis

Author:
Valguarnera, Ezequiel; Kinsella, Rachel L.; Feldman, Mario F.
Source:
Journal of Molecular Biology 2016
ISSN:
0022-2836
Subject:
toxins,   etc   ; diagnostic techniques; lipopolysaccharides; monosaccharides; bacterial proteins; flagellum; pathogenesis; glycoproteins; pathogens; bacterial infections; humans; vaccine development; oligosaccharides; biosynthesis; antibiotic resistance; antibiotics; glycosylation; host-pathogen relationships; spices; bacteria;     Show all 20 Subjects
Abstract:
... Protein glycosylation is a post-translational modification that occurs across the whole tree of life. In the recent years, multiple N- and O-glycosylation mechanisms have been identified and characterized in diverse bacterial species, including human pathogens. This review focuses on bacterial protein glycosylation and its impact in pathogenesis. Bacteria carry N- and O-glycosylation systems that ...
DOI:
10.1016/j.jmb.2016.04.013

8. The sequence, structural, and functional diversity within a protein family and implications for specificity and safety: The case for ETX_MTX2 insecticidal proteins

Author:
Moar, William J.; Evans, Adam J.; Kessenich, Colton R.; Baum, James A.; Bowen, David J.; Edrington, Thomas C.; Haas, Jeffrey A.; Kouadio, Jean-Louis K.; Roberts, James.K.; Silvanovich, Andre; Yin, Yong; Weiner, Brian E.; Glenn, Kevin C.; Odegaard, Matthew L.
Source:
Journal of invertebrate pathology 2016
ISSN:
0022-2011
Subject:
toxins,   etc   ; Bacillus thuringiensis; amino acid sequences; bioinformatics; functional diversity; insect pests; insecticidal proteins; oligomerization; pest control; safety assessment; sequence analysis; weight-of-evidence;     Show all 12 Subjects
Abstract:
... The need for sustainable insect pest control is driving the investigation and discovery of insecticidal proteins outside of the typical 3- domain Cry protein family from Bacillus thuringiensis (Bt). Examples include Cry35 and Cry51 that belong to protein families (Toxin_10, ETX_MTX2) sharing a common β-pore forming structure and function with known mammalian toxins such as epsilon toxin (ETX). Alt ...
DOI:
10.1016/j.jip.2016.05.007

9. Validation of Two New Immunoassays for Sensitive Detection of a Broad Range of Shiga Toxins

Author:
Kong, Q.; Patfield, S.; Skinner, C. B; Stanker, L. H.; Gehring, A. G.; Fratamico, P. M.; Rubio, F.; Qi, W.; He, X.
Source:
Austin Immunology 2016 v.1 no.2 pp. 1007
Subject:
Shiga toxin,   etc   ; agar; culture media; detection limit; diagnostic sensitivity; digestive system diseases; enterohemorrhagic Escherichia coli; enzyme-linked immunosorbent assay; fresh produce; humans; reproducibility; virulence;     Show all 12 Subjects
Abstract:
... Shiga Toxin (Stx) is one of the major virulence factors produced by Shiga Toxin-producing E. coli (STEC) that cause severe human intestinal diseases. Although a few commercial assays for Stxs are available, they only detect a subset of Stxs. In this study, two new immunoassays, Abraxis Stx1 and Stx2, were evaluated and compared with the widely used Premier EHEC kit using the same set of standards ...

10. Are harmful algal blooms becoming the greatest inland water quality threat to public health and aquatic ecosystems?

Author:
Brooks, Bryan W.; Lazorchak, James M.; Howard, Meredith D.A.; Johnson, Mari‐Vaughn V.; Morton, Steve L.; Perkins, Dawn A.K.; Reavie, Euan D.; Scott, Geoffrey I.; Smith, Stephanie A.; Steevens, Jeffery A.
Source:
Environmental toxicology and chemistry 2016 v.35 no.1 pp. 6-13
ISSN:
0730-7268
Subject:
toxins,   etc   ; algal blooms; aquatic ecosystems; chemistry; developed countries; drinking water; ecologists; ecotoxicology; engineers; environmental impact; fisheries; inland waters; monitoring; public health; recreation; risk assessment; surface water; water quality;     Show all 18 Subjects
Abstract:
... In this Focus article, the authors ask a seemingly simple question: Are harmful algal blooms (HABs) becoming the greatest inland water quality threat to public health and aquatic ecosystems? When HAB events require restrictions on fisheries, recreation, and drinking water uses of inland water bodies significant economic consequences result. Unfortunately, the magnitude, frequency, and duration of ...
DOI:
10.1002/etc.3220

11. A single-point mutation enhances dual functionality of a scorpion toxin Toxicology & pharmacology

Author:
Wang, Xueli; Gao, Bin; Zhu, Shunyi
Source:
Comparative biochemistry and physiology 2016 v.179 pp. 72-78
ISSN:
1532-0456
Subject:
toxins,   etc   ; Drosophila; Escherichia coli; Scorpiones; asparagine; bacteria; drugs; mammals; messenger RNA; mutants; mutation; peptide libraries; potassium channels; proline; toxicity; venoms;     Show all 16 Subjects
Abstract:
... Scorpion venom represents a tremendous, hitherto partially explored peptide library that has been proven to be useful not only for understanding ion channels but also for drug design. MeuTXKα3 is a functionally unknown scorpion toxin-like peptide. Here we describe new transcripts of this gene arising from alternative polyadenylation and its biological function as well as a mutant with a single-poi ...
DOI:
10.1016/j.cbpc.2015.09.002

12. Bioactive compounds of marine dinoflagellate isolates from western Greenland and their phylogenetic association within the genus Alexandrium

Author:
Tillmann, Urban; Krock, Bernd; Alpermann, Tilman J.; Cembella, Allan
Source:
Harmful algae 2016 v.51 pp. 67-80
ISSN:
1568-9883
Subject:
toxins,   etc   ; Alexandrium; Rhodomonas; algae; biogeography; biomarkers; coasts; paralytic shellfish poisoning; phenotype; phylogeny; prediction; ribosomal DNA; ribotypes; sequence analysis; shellfish; Arctic region; Greenland;     Show all 17 Subjects
Abstract:
... The diversity and biogeography of populations of the toxigenic marine dinoflagellate genus Alexandrium, a major global cause of paralytic shellfish poisoning (PSP), are represented by only a few studies based upon a low number of cultured isolates and remain poorly described in Arctic and sub-Arctic waters. Multiple clonal isolates (n=22) of the Alexandrium tamarense species complex, and a single ...
DOI:
10.1016/j.hal.2015.11.004

13. BMAA extraction of cyanobacteria samples: which method to choose?

Author:
Lage, Sandra; Burian, Alfred; Rasmussen, Ulla; Costa, Pedro Reis; Annadotter, Heléne; Godhe, Anna; Rydberg, Sara
Source:
Environmental science and pollution research international 2016 v.23 no.1 pp. 338-350
ISSN:
0944-1344
Subject:
cyanobacterial toxins,   etc   ; Bacillariophyceae; Dinophyceae; analytical methods; bioaccumulation; derivatization; guidelines; hydrolysis; invertebrates; nervous system diseases; neurotoxins; phytoplankton; terrestrial ecosystems; variance; vertebrates;     Show all 15 Subjects
Abstract:
... β-N-Methylamino-L-alanine (BMAA), a neurotoxin reportedly produced by cyanobacteria, diatoms and dinoflagellates, is proposed to be linked to the development of neurological diseases. BMAA has been found in aquatic and terrestrial ecosystems worldwide, both in its phytoplankton producers and in several invertebrate and vertebrate organisms that bioaccumulate it. LC-MS/MS is the most frequently use ...
DOI:
10.1007/s11356-015-5266-0

14. Chemical, molecular, and eco-toxicological investigation of Ostreopsis sp. from Cyprus Island: structural insights into four new ovatoxins by LC-HRMS/MS

Author:
Tartaglione, Luciana; Mazzeo, Antonia; Dell’Aversano, Carmela; Forino, Martino; Giussani, Valentina; Capellacci, Samuela; Penna, Antonella; Asnaghi, Valentina; Faimali, Marco; Chiantore, Mariachiara; Yasumoto, Takeshi; Ciminiello, Patrizia
Source:
Analytical and bioanalytical chemistry 2016 v.408 no.3 pp. 915-932
ISSN:
1618-2642
Subject:
marine toxins,   etc   ; Artemia salina; Dinophyceae; carbon; humans; nauplii; risk; toxicity; Cyprus; Mediterranean region;     Show all 10 Subjects
Abstract:
... Blooms of benthic dinoflagellates of the genus Ostreopsis (mainly O. cf. ovata and occasionally O. cf. siamensis) represent a serious concern for humans in the Mediterranean area, due to production of palytoxin-like compounds listed among the most potent marine toxins known. In this work, six strains of Ostreopsis sp. from Cyprus Island were analyzed through an integrated approach based on molecul ...
DOI:
10.1007/s00216-015-9183-3

15. Comparative analysis of the Shiga toxin converting bacteriophage first detected in Shigella sonnei

Author:
Tóth, István; Sváb, Domonkos; Bálint, Balázs; Brown-Jaque, Maryury; Maróti, Gergely
Source:
Infection, genetics, and evolution 2016 v.37 pp. 150-157
ISSN:
1567-1348
Subject:
Shiga toxin,   etc   ; Escherichia coli K12; Podoviridae; Shigella dysenteriae; Shigella sonnei; bacteriophages; cell culture; chromosomes; cytotoxicity; databases; genomics; hosts; open reading frames; operon; proteins;     Show all 15 Subjects
Abstract:
... Here we report the first complete nucleotide sequence of a Shiga toxin (Stx) converting phage from a Shigella sonnei clinical isolate that harbors stx1 operon, first identified in the chromosome of Shigella dysenteriae type 1. The phage named Shigella phage 75/02 Stx displayed Podoviridae morphology. It proved to be transferable to Escherichia coli K-12 strains, and cytotoxicity of the lysogenized ...
DOI:
10.1016/j.meegid.2015.11.022

16. Comparison of four rapid test kits for the detection of okadaic acid-group toxins in bivalve shellfish from Argentina

Author:
Turner, Andrew D.; Goya, Alejandra B.
Source:
Food control 2016 v.59 pp. 829-840
ISSN:
0956-7135
Subject:
toxins,   etc   ; Bivalvia; analytical kits; consumer protection; diarrhetic shellfish poisoning; enzyme-linked immunosorbent assay; product testing; shellfish; Argentina;     Show all 9 Subjects
Abstract:
... Analysis of bivalve molluscs for Diarrhetic Shellfish Poisoning is challenging for producers of shellfish who are unlikely to have access to LC-MS/MS technology for toxin testing. Four commercial rapid testing kits were applied to the analysis of Argentinean shellfish for DSP toxins, comparing results against the regulatory LC-MS/MS method. On the whole the specificity of the methods was good, wit ...
DOI:
10.1016/j.foodcont.2015.07.005

17. Culture‐Independent Rapid Detection Methods for Bacterial Pathogens and Toxins in Food Matrices

Author:
Wang, Yun; Salazar, Joelle K.
Source:
Comprehensive reviews in food science and food safety 2016 v.15 no.1 pp. 183-205
ISSN:
1541-4337
Subject:
Shiga toxin-producing Escherichia coli; bacterial toxins,   etc   ; Listeria monocytogenes; Salmonella enterica; food matrix; food pathogens; foodborne illness; foods; microbial detection; probability; public health; rapid methods;     Show all 12 Subjects
Abstract:
... Rapid detection of bacterial pathogens and toxins in foods is necessary to provide real‐time results to mitigate foodborne illness outbreaks. Cultural enrichment methods, although the most widely used, are time‐consuming and therefore inadequate for rapid pathogen detection from food samples. The development of novel “rapid” detection methods has decreased detection time dramatically. This review ...
DOI:
10.1111/1541-4337.12175

18. Effect of the endoparasite Amoebophrya sp. on toxin content and composition in the paralytic shellfish poisoning dinoflagellate Alexandrium fundyense (Dinophyceae)

Author:
Kim, Sunju; Park, Myung Gil
Source:
Harmful algae 2016 v.51 pp. 10-15
ISSN:
1568-9883
Subject:
toxins,   etc   ; Alexandrium; algae; algal blooms; ecosystems; endoparasites; molecular biology; paralytic shellfish poisoning; parasitism; phylogeny; poisoning; shellfish; toxicity;     Show all 13 Subjects
Abstract:
... Members of the Amoebophrya ceratii complex are endoparasitic dinoflagellates that parasitize a number of their dinoflagellate relatives, including toxic and/or harmful algal bloom-forming species. Despite many studies on the occurrence, prevalence, biology and molecular phylogeny of Amoebophrya spp., little attention has been given to toxin dynamics of host population following parasitism. Using A ...
DOI:
10.1016/j.hal.2015.10.016

19. Entomotoxic and nematotoxic lectins and protease inhibitors from fungal fruiting bodies

Author:
Sabotič, Jerica; Ohm, Robin A.; Künzler, Markus
Source:
Applied microbiology and biotechnology 2016 v.100 no.1 pp. 91-111
ISSN:
0175-7598
Subject:
toxins,   etc   ; Nematoda; animals; biosynthesis; fruiting bodies; fungivores; genome; insects; lectins; medicine; mushrooms; phylogeny; plant protection; predators; proteinase inhibitors;     Show all 15 Subjects
Abstract:
... Fruiting bodies or sporocarps of dikaryotic (ascomycetous and basidiomycetous) fungi, commonly referred to as mushrooms, are often rich in entomotoxic and nematotoxic proteins that include lectins and protease inhibitors. These protein toxins are thought to act as effectors of an innate defense system of mushrooms against animal predators including fungivorous insects and nematodes. In this review ...
DOI:
10.1007/s00253-015-7075-2

20. Factors controlling permeability of the blood–brain barrier

Author:
Almutairi, Mohammed M. A.; Gong, Chen; Xu, Yuexian G.; Chang, Yanzhong; Shi, Honglian
Source:
Cellular and molecular life sciences 2016 v.73 no.1 pp. 57-77
ISSN:
1420-682X
Subject:
toxins,   etc   ; astrocytes; blood; blood-brain barrier; brain; endothelial cells; free radicals; integrins; ions; isoflurane; metalloproteinases; microRNA; neurons; nutrients; parenchyma (animal tissue); permeability; tight junctions; vascular endothelial growth factors;     Show all 18 Subjects
Abstract:
... As the primary protective barrier for neurons in the brain, the blood–brain barrier (BBB) exists between the blood microcirculation system and the brain parenchyma. The normal BBB integrity is essential in protecting the brain from systemic toxins and maintaining the necessary level of nutrients and ions for neuronal function. This integrity is mediated by structural BBB components, such as tight ...
DOI:
10.1007/s00018-015-2050-8

21. Fast detection of both O157 and non‐O157 shiga‐toxin producing Escherichia coli by real‐time optical immunoassay

Author:
Mondani, L.; Delannoy, S.; Mathey, R.; Piat, F.; Mercey, T.; Slimani, S.; Fach, P.; Livache, T.; Roupioz, Y.
Source:
Letters in applied microbiology 2016 v.62 no.1 pp. 39-46
ISSN:
0266-8254
Subject:
Shiga toxin-producing Escherichia coli,   etc   ; antibody microarrays; foods; image analysis; cell viability; immunoassays; serotypes; polymerase chain reaction; pathogens; cost effectiveness; surface plasmon resonance;     Show all 11 Subjects
Abstract:
... Among bacterial pathogens involved in food‐illnesses, seven serogroups (O26, O45, O103, O111, O121, O145 and O157) of Shiga‐toxin producing Escherichia coli (STEC), are frequently identified. During such outbreak, and due to the perishable property of most foodstuff, the time laps for the identification of contaminated products and pathogens is thus critical to better circumvent their spread. Trad ...
DOI:
10.1111/lam.12503

22. High instability of a nematicidal Cry toxin plasmid in Bacillus thuringiensis

Author:
Sheppard, Anna E.; Nakad, Rania; Saebelfeld, Manja; Masche, Anna C.; Dierking, Katja; Schulenburg, Hinrich
Source:
Journal of invertebrate pathology 2016 v.133 pp. 34-40
ISSN:
0022-2011
Subject:
toxins,   etc   ; Bacillus thuringiensis; Caenorhabditis elegans; Escherichia coli; crystal proteins; evolution; genome; insecticidal proteins; interspersed repetitive sequences; invertebrates; pathogens; plasmids; virulence;     Show all 13 Subjects
Abstract:
... In bacterial pathogens, virulence factors are often carried on plasmids and other mobile genetic elements, and as such, plasmid evolution is central in understanding pathogenicity. Bacillus thuringiensis is an invertebrate pathogen that uses plasmid-encoded crystal (Cry) toxins to establish infections inside the host. Our study aimed to quantify stability of two Cry toxin-encoding plasmids, BTI_23 ...
DOI:
10.1016/j.jip.2015.11.009

23. Identification, characterization and immunological analysis of Ras related C3 botulinum toxin substrate 1 (Rac1) from grass carp Ctenopharyngodon idella

Author:
Hu, Mo-Yan; Shen, Yu-Bang; Xu, Xiao-Yan; Yu, Hong-Yan; Zhang, Meng; Dang, Yun-Fei; Li, Jia-Le
Source:
Developmental and comparative immunology 2016 v.54 no.1 pp. 20-31
ISSN:
0145-305X
Subject:
botulinum toxin,   etc   ; Aeromonas hydrophila; Ctenopharyngodon idella; Danio rerio; complementary DNA; flagellin; guanosinetriphosphatase; innate immunity; mammals; nuclear localization signals; open reading frames; phylogeny; tissue distribution; transcription factor NF-kappa B;     Show all 14 Subjects
Abstract:
... Rac1, a Rho GTPase, serves critical immunological functions in mammals. Here, a Rac1 homolog (gcRac1) was identified in grass carp (Ctenopharyngodon idella). The full-length 2023-base pair gcRac1 cDNA contained a 579-bp open reading frame encoding a 192-residue protein, including a conserved RHO domain and nuclear localization signal. The gcRac1 protein shares high identity with other Rac1 counter ...
DOI:
10.1016/j.dci.2015.08.010

24. Inheritance of Bacillus thuringiensis Cry1C resistance in Egyptian cotton leafworm, Spodoptera littoralis (Lepidoptera: Noctuidae)

Author:
Moussa, Saad; Kamel, Essam; Ismail, Ismail M.; Mohammed, Ahmed
Source:
Entomological research 2016 v.46 no.1 pp. 61-69
ISSN:
1738-2297
Subject:
bacterial toxins,   etc   ; Bacillus thuringiensis; Spodoptera littoralis; backcrossing; bioassays; crystal proteins; females; inheritance (genetics); insecticide resistance; loci; males; progeny; reciprocal crosses;     Show all 13 Subjects
Abstract:
... A field strain of Spodoptera littoralis Biosduval was selected against Cry1C toxin derived from Bacillus thuringiensis entomocidus for 10 subsequent generations under laboratory conditions. Selection pressure resulted in a 29‐fold resistance ratio compared with the susceptible strain. Inheritance of Cry1C resistance was partially dominant and autosomal on the basis of bioassay response to Cry1C to ...
DOI:
10.1111/1748-5967.12148

25. In vivo exposure to northern diatoms arrests sea urchin embryonic development

Author:
Gudimova, Elena; Eilertsen, Hans C.; Jørgensen, Trond Ø.; Hansen, Espen
Source:
Toxicon 2016 v.109 pp. 63-69
ISSN:
0041-0101
Subject:
toxins,   etc   ; Attheya; Bacillariophyceae; Chaetoceros; Echinus; Porosira; Skeletonema; Strongylocentrotus droebachiensis; Thalassiosira; cell suspension culture; developmental stages; egg incubation; eggs; embryogenesis; grazing; hatching; invertebrates; mortality; oxylipins; polyunsaturated fatty acids;     Show all 20 Subjects
Abstract:
... There are numerous reports indicating that marine diatoms may act harmful to early developmental stages of invertebrates. It is believed that the compounds responsible for these detrimental effects are oxylipins resulting from oxidized polyunsaturated fatty acids, and that they may function as grazing deterrents. Most studies reporting these effects have exposed test organisms to diatom extracts o ...
DOI:
10.1016/j.toxicon.2015.11.001

26. Multi-mycotoxin stable isotope dilution LC-MS/MS method for Fusarium toxins in cereals

Author:
Habler, Katharina; Rychlik, Michael
Source:
Analytical and bioanalytical chemistry 2016 v.408 no.1 pp. 307-317
ISSN:
1618-2642
Subject:
T-2 toxin,   etc   ; 15-acetyldeoxynivalenol; 3-acetyldeoxynivalenol; Fusarium; chromatography; deoxynivalenol; deoxynivalenol-3-glucoside; grains; isotope dilution technique; malting barley; nivalenol; solid phase extraction; stable isotopes; zearalenone;     Show all 14 Subjects
Abstract:
... A multi-mycotoxin stable isotope dilution LC-MS/MS method was developed for 14 Fusarium toxins including modified mycotoxins in cereals (deoxynivalenol, 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, HT2-toxin, T2-toxin, enniatin B, enniatin B1, enniatin A1, enniatin A, beauvericin, fusarenone X, nivalenol, deoxynivalenol-3-glucoside, and zearalenone). The chromatographic separation of the toxin ...
DOI:
10.1007/s00216-015-9110-7

27. Multiplex Quantitative PCR Assays for the Detection and Quantification of the Six Major Non-O157 Escherichia coli Serogroups in Cattle Feces

Author:
Shridhar, P. B.; Noll, L. W.; Shi, X.; An, B.; Cernicchiaro, N.; Renter, D. G.; Nagaraja, T. G.; Bai, J.
Source:
Journal of food protection 2016 v.79 no.1 pp. 66-74
ISSN:
0362-028X
Subject:
Shiga toxin-producing Escherichia coli,   etc   ; antigens; cattle; detection limit; feces; feedlots; food pathogens; genes; hindgut; quantitative polymerase chain reaction; serotypes; virulence;     Show all 12 Subjects
Abstract:
... Shiga toxin–producing Escherichia coli (STEC) serogroups O26, O45, O103, O111, O121, and O145, called non-O157 STEC, are important foodborne pathogens. Cattle, a major reservoir, harbor the organisms in the hindgut and shed them in the feces. Although limited data exist on fecal shedding, concentrations of non-O157 STEC in feces have not been reported. The objectives of our study were (i) to devel ...
DOI:
10.4315/0362-028X.JFP-15-319

28. Nanomaterial-based sensors for detection of foodborne bacterial pathogens and toxins as well as pork adulteration in meat products

Author:
Stephen Inbaraj, B.; Chen, B.H.
Source:
Yàowù shípǐn fēnxī 2016 v.24 no.1 pp. 15-28
ISSN:
1021-9498
Subject:
toxins,   etc   ; adulterated products; biosensors; carbon nanotubes; control methods; drugs; eating habits; food analysis; food industry; food packaging; food safety; human health; human resources; nanoparticles; pathogens; pork; preservatives; quantum dots; recipes; shelf life;     Show all 20 Subjects
Abstract:
... Food safety draws considerable attention in the modern pace of the world owing to rapid-changing food recipes and food habits. Foodborne illnesses associated with pathogens, toxins, and other contaminants pose serious threat to human health. Besides, a large amount of money is spent on both analyses and control measures, which causes significant loss to the food industry. Conventional detection me ...
DOI:
10.1016/j.jfda.2015.05.001

29. Nocardiopsis species: a potential source of bioactive compounds

Author:
Bennur, T.; Ravi Kumar, A.; Zinjarde, S.S.; Javdekar, V.
Source:
Journal of applied microbiology 2016 v.120 no.1 pp. 1-16
ISSN:
1364-5072
Subject:
toxins,   etc   ; Nocardiopsis; amines; anti-infective agents; antineoplastic agents; bioactive properties; immunomodulators; ligases; multigene family; neoplasms; peptides; photoaging; polyketide synthases; polyketides; quinoline alkaloids; salt tolerance; soil; solutes; surfactants;     Show all 19 Subjects
Abstract:
... Members of the genus Nocardiopsis are an ecologically versatile and biotechnologically important group of Actinomycetes. Most of the isolates are halotolerant or halophilic and they prevail in soils, marine environments or hypersaline locations. To aid their survival under these conditions, they mainly produce extremozymes, compatible solutes, surfactants and bioactive compounds. The current revie ...
DOI:
10.1111/jam.12950

30. Outbreak of Haff Disease caused by consumption of crayfish (Procambarus clarkii), Nanjing, Jiangsu Province, China

Author:
Chen, Yan; Yuan, Baojun; Xie, Guoxiang; Zhen, Shiqi; Zhou, Yijing; Shao, Bing; Zhang, Jing; Ji, Hua; Wu, Yongning
Source:
Food control 2016 v.59 pp. 690-694
ISSN:
0956-7135
Subject:
toxins,   etc   ; Procambarus clarkii; blood; case-control studies; chemical analysis; cooked foods; crayfish; drugs; etiology; exposure duration; markets; monitoring; outbreak investigation; questionnaires; rhabdomyolysis; risk; urine; China;     Show all 18 Subjects
Abstract:
... Haff disease is a rare syndrome characterized by rhabdomyolysis following consumption of cooked fish or crustaceans. We present the investigation of an outbreak of Haff disease in Nanjing, Jiangsu Province, China incorporating both epidemiological and chemical analysis. Structured questionnaires were sent to 20 case-patients and 25 diners who ate with case-patients. Eleven samples of crayfish (Pro ...
DOI:
10.1016/j.foodcont.2015.06.031

31. Phycogeography of freshwater phytoplankton: traditional knowledge and new molecular tools

Author:
Padisák, Judit; Vasas, Gábor; Borics, Gábor
Source:
Hydrobiologia 2016 v.764 no.1 pp. 3-27
ISSN:
0018-8158
Subject:
cyanobacterial toxins,   etc   ; biogeography; freshwater; geographical distribution; habitats; indigenous knowledge; metabolomics; molecular genetics; phylogeny; phytoplankton; secondary metabolites;     Show all 11 Subjects
Abstract:
... “Everything is everywhere, but environments selects.” Is this true? The cosmopolitan nature of algae, including phytoplankton, has been highlighted in many textbooks and burnt into the minds of biologists during their studies. However, the accumulating knowledge on the occurrence of individual phytoplankton species in habitats where they have not been seen before, reports on invasive phytoplankton ...
DOI:
10.1007/s10750-015-2259-4

32. Pooling of Immunomagnetic Separation Beads Does Not Affect Detection Sensitivity of Six Major Serogroups of Shiga Toxin–Producing Escherichia coli in Cattle Feces

Author:
Noll, Lance W.; Baumgartner, William C.; Shridhar, Pragathi B.; Cull, Charley A.; Dewsbury, Diana M.; Shi, Xiaorong; Cernicchairo, Natalia; Renter, David G.; Nagaraja, T. G.
Source:
Journal of food protection 2016 v.79 no.1 pp. 59-65
ISSN:
0362-028X
Subject:
Shiga toxin-producing Escherichia coli,   etc   ; cattle; detection limit; feces; food pathogens; foods; hindgut; immunomagnetic separation; labor; serotypes;     Show all 10 Subjects
Abstract:
... Shiga toxin–producing Escherichia coli (STEC) of the serogroups O26, O45, O103, O111, O121, and O145, often called non-O157 STEC, are foodborne pathogens. Cattle are asymptomatic reservoirs for STEC; the organisms reside in the hindgut and are shed in the feces, which serve as the source of food product contaminations. Culture-based detection of non-O157 STEC involves an immunomagnetic separation ...
DOI:
10.4315/0362-028X.JFP-15-236

33. Recent advances in the application of capillary electromigration methods for food analysis and Foodomics

Author:
Acunha, Tanize; Ibáñez, Clara; García‐Cañas, Virginia; Simó, Carolina; Cifuentes, Alejandro
Source:
Electrophoresis 2016 v.37 no.1 pp. 111-141
ISSN:
0173-0835
Subject:
toxins,   etc   ; amines; amino acids; capillary electrophoresis; carbohydrates; food additives; food analysis; food processing; inorganic compounds; lipids; mass spectrometry; monitoring; nutritive value; peptides; pesticides; physicochemical properties; polyphenols; proteins; vitamins;     Show all 19 Subjects
Abstract:
... This review work presents and discusses the main applications of capillary electromigration methods in food analysis and Foodomics. Papers that were published during the period February 2013–February 2015 are included following the previous review by Garcia‐Cañas et al. (Electrophoresis, 2014, 35, 147–169). Analysis by CE of a large variety of food‐related molecules with different chemical propert ...
DOI:
10.1002/elps.201500291

34. Shiga toxin-producing Escherichia coli in food: Incidence, ecology, and detection strategies

Author:
Baker, Christopher A.; Rubinelli, Peter M.; Park, Si Hong; Carbonero, Franck; Ricke, Steven C.
Source:
Food control 2016 v.59 pp. 407-419
ISSN:
0956-7135
Subject:
Shiga toxin; Shiga toxin-producing Escherichia coli,   etc   ; adulterated products; ecology; foodborne illness; ground beef; microorganisms; pathogens; raw meat; serotypes;     Show all 10 Subjects
Abstract:
... Commensal Escherichia coli are commonly utilized for investigating the genetic and biochemical requirements of microorganisms, and have served in a wide variety of applications. Pathogenic E. coli known as Shiga toxin (Stx)-producing E. coli (STEC) are associated with various food products including ground beef. These pathogens are present in a wide range of environments, and have caused numerous ...
DOI:
10.1016/j.foodcont.2015.06.011

35. Strategies for upgrading analyte detection in immuno-PCR studied on identification of type A botulinum neurotoxin

Author:
Ryabko, A. K.; Kozyr’, A. V.; Kolesnikov, A. V.; Khlyntseva, A. E.; Zharnikova, I. V.; Shemyakin, I. G.
Source:
Applied biochemistry and microbiology 2016 v.52 no.1 pp. 110-120
ISSN:
0003-6838
Subject:
botulinum toxin,   etc   ; DNA; neurotoxins; polyclonal antibodies; quantitative polymerase chain reaction;     Show all 5 Subjects
Abstract:
... An efficient method of highly sensitive, specific determination of botulinic type A neurotoxin (which allows the detection of a toxin in a concentration from 1 pg/mL (10 fg per one PCR reaction) was created based on the technology of immuno-PCR. Solid phase consisting of paramagnetic organo–silicious particles carrying a detection complex of the toxin heavy chain with a pair of polyclonal antibodi ...
DOI:
10.1134/S0003683816010117

36. Stress signaling in mammalian oocytes and embryos: a basis for intervention and improvement of outcomes

Author:
Latham, Keith E.
Source:
Cell and tissue research 2016 v.363 no.1 pp. 159-167
ISSN:
0302-766X
Subject:
toxins,   etc   ; amino acids; endoplasmic reticulum; epigenetics; lipids; mammals; oocytes; osmolarity; oxygen; protein synthesis; shear stress; temperature;     Show all 12 Subjects
Abstract:
... Oocytes and early stage embryos are highly sensitive to variation in diverse exogenous factors such as temperature, osmolarity, oxygen, nutrient restriction, pH, shear stress, toxins, amino acid availability, and lipids. It is becoming increasingly apparent that many such factors negatively affect the endoplasmic reticulum, protein synthesis and protein processing, initiating ER stress and unfolde ...
DOI:
10.1007/s00441-015-2124-9
PubMed:
25743689
PubMed Central:
PMC4561599

37. Targeting c-kit receptor in neuroblastomas and colorectal cancers using stem cell factor (SCF)-based recombinant bacterial toxins

Author:
Choudhary, Swati; Pardo, Alessa; Rosinke, Reinhard; Batra, Janendra K.; Barth, Stefan; Verma, Rama S.
Source:
Applied microbiology and biotechnology 2016 v.100 no.1 pp. 263-277
ISSN:
0175-7598
Subject:
bacterial toxins,   etc   ; Pseudomonas; autocrine signaling; breast neoplasms; colorectal neoplasms; cytotoxicity; exotoxins; gastrointestinal system; lung neoplasms; mutation; neoplasm cells; receptor protein-tyrosine kinase; stem cell factor; therapeutics; tyrosine;     Show all 15 Subjects
Abstract:
... Autocrine activation of c-kit (KIT receptor tyrosine kinase) has been postulated to be a potent oncogenic driver in small cell lung cancer, neuroblastoma (NB), and poorly differentiated colorectal carcinoma (CRC). Although targeted therapy involving tyrosine kinase inhibitors (TKIs) such as imatinib mesylate is highly effective for gastrointestinal stromal tumor carrying V560G c-kit mutation, it d ...
DOI:
10.1007/s00253-015-6978-2

38. Toxicity and oxidative stress induced by T-2 toxin and HT-2 toxin in broilers and broiler hepatocytes

Author:
Yang, Lingchen; Yu, Zezhong; Hou, Jiafa; Deng, Yifeng; Zhou, Zhenlei; Zhao, Zhiyong; Cui, Jun
Source:
Food and chemical toxicology 2016 v.87 pp. 128-137
ISSN:
0278-6915
Subject:
HT-2 toxin; T-2 toxin,   etc   ; Fusarium poae; alanine transaminase; aspartate transaminase; blood proteins; body weight; cell viability; chickens; corn; feed conversion; foods; gene expression; glutathione peroxidase; hepatocytes; humans; messenger RNA; oxidative stress; reactive oxygen species; superoxide dismutase; toxicity; toxicology; weight gain;     Show all 23 Subjects
Abstract:
... T-2 and HT-2 toxins belong to mycotoxins which are found in human foods and animal chow. We investigated the toxicity and oxidative stress induced by T-2/HT-2 in broilers and chicken hepatocytes. Maize cultures of Fusarium poae was fed to broilers for 42 d, and the physiological index, biochemical index and expression of mRNAs related to oxidative stress were analyzed. Chicken hepatocytes were tre ...
DOI:
10.1016/j.fct.2015.12.003

39. Variability in resistance to Cold Atmospheric Plasma (CAP) and Ultraviolet light (UV) and multiple stress resistance analysis of pathogenic verocytotoxigenic Escherichia coli (VTEC)

Author:
Prieto-Calvo, M.A.; López, M.; Prieto, M.; Alvarez-Ordóñez, A.
Source:
Food research international 2016 v.79 pp. 88-94
ISSN:
0963-9969
Subject:
Shiga toxin-producing Escherichia coli,   etc   ; Fourier transform infrared spectroscopy; biofilm; cell walls; cold; discriminant analysis; epidemiology; equipment; heat; high pressure treatment; human diseases; multivariate analysis; mutation; nucleic acids; principal component analysis; serotypes; stress response; stress tolerance; ultraviolet radiation;     Show all 19 Subjects
Abstract:
... This study assessed the resistance to Ultraviolet light (UV) and Cold Atmospheric Plasma (CAP) of ten verocytotoxigenic Escherichia coli (VTEC) isolates and two laboratory non-pathogenic E. coli strains and monitored the effects that UV and CAP have on VTEC molecular composition by using Fourier transform infrared (FTIR) spectroscopy. In addition, serotype-related resistance patterns to different ...
DOI:
10.1016/j.foodres.2015.12.004

40. Whole genome sequencing of diverse Shiga toxin-producing and non-producing Escherichia coli strains reveals a variety of virulence and novel antibiotic resistance plasmids

Author:
Losada, Liliana; DebRoy, Chitrita; Radune, Diana; Kim, Maria; Sanka, Ravi; Brinkac, Lauren; Kariyawasam, Subhashinie; Shelton, Daniel; Fratamico, Pina M.; Kapur, Vivek; Feng, Peter C.H.
Source:
Plasmid 2016 v.83 pp. 8-11
ISSN:
0147-619X
Subject:
Shiga toxin-producing Escherichia coli,   etc   ; aminoglycosides; antibiotic resistance; cephalosporins; chloramphenicol; dihydrofolate reductase; genes; heavy metals; penicillins; plasmids; sequence analysis; serotypes; sulfonamides; tetracyclines; virulence;     Show all 15 Subjects
Abstract:
... The genomes of a diverse set of Escherichia coli , including many Shiga toxin-producing strains of various serotypes were determined. A total of 39 plasmids were identified among these strains, and many carried virulence or putative virulence genes of Shiga toxin-producing E. coli strains, virulence genes for other pathogenic E. coli groups, and some had combinations of these genes. Among the nove ...
Handle:
10113/61857
DOI:
10.1016/j.plasmid.2015.12.001

41. Heavy metal accumulation and toxicity in smoothhound (Mustelus mustelus) shark from Langebaan Lagoon, South Africa

Author:
Bosch, Adina C.; O’Neill, Bernadette; Sigge, Gunnar O.; Kerwath, Sven E.; Hoffman, Louwrens C.
Source:
Food chemistry 2016 v.190 pp. 871-878
ISSN:
0308-8146
Subject:
toxins,   etc   ; Mustelus mustelus; arsenic; atomic absorption spectrometry; fillets; fish meat; heavy metals; mercury; methylmercury compounds; predatory fish; sharks; toxicity; South Africa;     Show all 13 Subjects
Abstract:
... Together with several health benefits, fish meat could introduce toxins to consumers in the form of heavy metal contaminants. High levels of mercury (Hg), especially, are frequently detected in certain predatory fish species. Mustelus mustelus fillets were analysed for 16 metals and three individual Hg species (inorganic Hg, ehtylmercury, methylmercury) with inductively coupled plasma mass spectro ...
DOI:
10.1016/j.foodchem.2015.06.034

42. Learning about aposematic prey

Author:
Skelhorn, John; Halpin, Christina G.; Rowe, Candy
Source:
Behavioral ecology 2016 v.27 no.4 pp. 955-964
ISSN:
1465-7279
Subject:
toxins,   etc   ; color; decision making; diet; learning; mimicry (behavior); predation; predators; toxicity;     Show all 9 Subjects
Abstract:
... Aposematic prey advertise their toxicity using conspicuous coloration. Many theories explaining the evolution of aposematic coloration assume that predators learn to associate the conspicuous coloration with the noxious effects of the toxins and subsequently avoid aposematic prey. Here, we promote the view that predators make informed decisions about when to sample aposematic prey to gather inform ...
DOI:
10.1093/beheco/arw009

43. Microbiote shift in the Medicago sativa rhizosphere in response to cyanotoxins extract exposure

Author:
El Khalloufi, Fatima; Oufdou, Khalid; Bertrand, Marie; Lahrouni, Majida; Oudra, Brahim; Ortet, Philippe; Barakat, Mohamed; Heulin, Thierry; Achouak, Wafa
Source:
The Science of the total environment 2016 v.539 pp. 135-142
ISSN:
0048-9697
Subject:
cyanobacterial toxins,   etc   ; Actinobacteria; Clostridia; Gemmatimonas; Medicago sativa; Opitutae; alpha-Proteobacteria; aquatic plants; bacteria; bacterial communities; beta-Proteobacteria; crops; delta-Proteobacteria; gamma-Proteobacteria; irrigation; niches; nutrients; phylogeny; polymerase chain reaction; rhizosphere; sequence analysis; soil; surface water; tissues; toxicity;     Show all 25 Subjects
Abstract:
... The bloom-containing water bodies may have an impact due to cyanotoxins production on other microorganisms and aquatic plants. Where such water is being used for crops irrigation, the presence of cyanotoxins may also have a toxic impact on terrestrial plants and their rhizosphere microbiota. For that purpose, PCR-based 454 pyrosequencing was applied to phylogenetically characterize the bacterial c ...
DOI:
10.1016/j.scitotenv.2015.08.127

44. Banned dinitrophenols still trigger both legal and forensic issues

Author:
Zaharia, Marius; Tudorachi, Lucia; Pintilie, Olga; Drochioi, Cristian; Gradinaru, Robert; Murariu, Manuela
Source:
Environmental forensics 2016 v.17 no.1 pp. 120-130
ISSN:
1527-5930
Subject:
toxins,   etc   ; 2,4-dinitrophenol; Internet; accidents; death; diet; dinoseb; drugs; environmental hazards; environmental health; forensic sciences; groundwater; ingredients; mechanism of action; metabolic inhibitors; polluted soils; toxicity; toxicology; weight loss;     Show all 19 Subjects
Abstract:
... Numerous hazardous chemicals from various industrial sources enter the environment daily; some of them can be used both as drugs and as toxins. Many of these compounds, including dinitrophenols, such as 2,4-dinitrophenol (2,4-DNP), 4,6-dinitrocresol (DNOC), and 2- sec -butyl-4,6-dinitrophenol (dinoseb), are widely used pesticides that persist in some contaminated soils. They have been found in gro ...
DOI:
10.1080/15275922.2015.1133735

45. Effect of commercial Bacillus thuringiensis toxins on Tyrophagus putrescentiae (Schrank) fed on wolfberry (Lycium barbarum L.)

Author:
Ahmed, Nevin; Wang, Mo; Shu, Shaohua
Source:
International journal of acarology 2016 v.42 no.1 pp. 1-6
ISSN:
1945-3892
Subject:
toxins,   etc   ; Bacillus thuringiensis; Lycium barbarum; Oriental traditional medicine; Tyrophagus putrescentiae; adults; fecundity; fruits; longevity; mortality; relative humidity; China;     Show all 12 Subjects
Abstract:
... A laboratory study was conducted at the Traditional Chinese Medicine Center in Huazhong Agricultural University, Wuhan, China. Two commercial Bacillus thuringiensis (Bt) toxins (var. israelensis and tenebrionis) were used in this study at six concentrations (0, 2, 4, 8, 16 and 32 mg kg ⁻¹). We evaluated the growth and some biological properties of Tyrophagus putrescentiae (Schrank) fed on one Chin ...
DOI:
10.1080/01647954.2015.1109707

46. Improved insecticidal activity of a genetically modified baculovirus expressing the immunosuppressive CrV1 protein from a polydnavirus against Spodoptera exigua

Author:
Wei, Lihua; Pérez-Rodríguez, Miguel Á.; Tamez-Guerra, Patricia; De Luna-Santillana, Erick de Jesús; Rosas-García, Ninfa M.; Villegas-Mendoza, Jesús M.; Rodríguez-Pérez, Mario A.
Source:
Biocontrol science and technology 2016 v.26 no.1 pp. 1-11
ISSN:
1360-0478
Subject:
toxins,   etc   ; Autographa californica multiple nucleopolyhedrovirus; Cotesia rubecula; Polydnaviridae; Spodoptera exigua; actin; biological control; biopesticides; complementary DNA; depolymerization; embryogenesis; enzymes; genes; hemocytes; hormones; immune system; insect pests; insecticidal properties; metabolism; metamorphosis; parasitic wasps; phagocytosis; protein secretion; virulence; viruses;     Show all 25 Subjects
Abstract:
... Recombinant baculoviruses could be used as biological insecticides through the introduction and expression of exogenous genes (such as those coding for proteins) that interfere with metabolism, metamorphosis (toxins, hormones, and enzymes), and immune system of the insects. The CrV1 secreted protein of Cotesia rubecula polydnavirus (PDV) is responsible for the actin depolymerisation in haemocytes ...
DOI:
10.1080/09583157.2015.1072129

47. Include mushroom in daily diet—A strategy for better hepatic health

Author:
Chatterjee, Ananya; Acharya, Krishnendu
Source:
Food reviews international 2016 v.32 no.1 pp. 68-97
ISSN:
1525-6103
Subject:
toxins,   etc   ; adverse effects; blood flow; cost effectiveness; drugs; functional foods; hepatotoxicity; liver; markets; mushrooms; spawning;     Show all 11 Subjects
Abstract:
... Liver, the most important metabolic organ of the body, is also the major organ for the detoxification of the blood stream. If the accumulation of toxins is faster than their removal by liver, hepatic damage occurs. Although synthetic drugs are available in the market, long-term use of such drugs has consequential side effects. Therefore, the growing need to find safe, cost-effective drugs devoid o ...
DOI:
10.1080/87559129.2015.1057839

48. Neutralizing antibody and functional mapping of Bacillus anthracis protective antigen—The first step toward a rationally designed anthrax vaccine

Author:
McComb, Ryan C.; Martchenko, Mikhail
Source:
Vaccine 2016 v.34 no.1 pp. 13-19
ISSN:
0264-410X
Subject:
anthrax toxin,   etc   ; Bacillus anthracis; Centers for Disease Control and Prevention; aluminum hydroxide; amino acids; anthrax; crystal structure; epitope mapping; mutation; neutralizing antibodies; pathogens; vaccination; vaccine development; vaccines;     Show all 14 Subjects
Abstract:
... Anthrax is defined by the Centers for Disease Control and Prevention as a Category A pathogen for its potential use as a bioweapon. Current prevention treatments include Anthrax Vaccine Adsorbed (AVA). AVA is an undefined formulation of Bacillus anthracis culture supernatant adsorbed to aluminum hydroxide. It has an onerous vaccination schedule, is slow and cumbersome to produce and is slightly re ...
DOI:
10.1016/j.vaccine.2015.11.025

49. Pertussis vaccination during pregnancy in Belgium: Results of a prospective controlled cohort study

Author:
Maertens, Kirsten; Caboré, Raïssa Nadège; Huygen, Kris; Hens, Niel; Van Damme, Pierre; Leuridan, Elke
Source:
Vaccine 2016 v.34 no.1 pp. 142-150
ISSN:
0264-410X
Subject:
pertussis toxin,   etc   ; antibodies; antigens; blood; cohort studies; enzyme-linked immunosorbent assay; gestational age; hemagglutinins; immune response; infants; maternal immunity; pregnancy; pregnant women; progeny; tetanus; vaccination; vaccines; Belgium;     Show all 18 Subjects
Abstract:
... Vaccination during pregnancy has been recommended in some countries as a means to protect young infants from severe infection. Nevertheless, many aspects are still unknown and possible blunting of the infant's immune responses by maternal antibodies, is one of the concerns with maternal vaccination. We report the first prospective controlled cohort study in women and infants on the effects of usin ...
DOI:
10.1016/j.vaccine.2015.10.100

50. Pertussis vaccination during pregnancy in Vietnam: Results of a randomized controlled trial Pertussis vaccination during pregnancy

Author:
Hoang, Ha Thi Thu; Leuridan, Elke; Maertens, Kirsten; Nguyen, Trung Dac; Hens, Niel; Vu, Ngoc Ha; Caboré, Raissa Nadège; Duong, Hong Thi; Huygen, Kris; Van Damme, Pierre; Dang, Anh Duc
Source:
Vaccine 2016 v.34 no.1 pp. 151-159
ISSN:
0264-410X
Subject:
pertussis toxin,   etc   ; antibodies; antigens; blood; enzyme-linked immunosorbent assay; gestational age; immunoglobulin G; infants; pregnancy; pregnant women; progeny; randomized clinical trials; tetanus; vaccination; vaccines; Vietnam;     Show all 16 Subjects
Abstract:
... A pertussis vaccination during pregnancy has recently been adopted in several countries to indirectly protect young infants. This study assessed the effect of adding a pertussis component to the tetanus vaccination, in the pregnancy immunization program in Vietnam.A randomized controlled trial was performed. Pregnant women received either a Tdap (tetanus, diphtheria acellular pertussis) vaccine or ...
DOI:
10.1016/j.vaccine.2015.10.098