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- Cesari, Italo M., et al. Show all 4 Authors
- Parasitology international 2016 v.65 no.3 pp. 191-195
- Schistosoma mansoni; adults; affinity chromatography; antigens; cathepsin B; diagnostic techniques; digestive system; hemoglobin; ion exchange; parasites; patients; polyclonal antibodies; proteolysis; rabbits; schistosomiasis
- ... Adult Schistosoma mansoni parasites have the capacity to degrade ingested host hemoglobin and other host plasma proteins by using a series of gut proteolytic enzymes, including cathepsin B; this enzyme is released to the host intravascular environment during regurgitations of adult worms. Cathepsin B becomes thus a circulating parasite component that has been shown to be specifically recognized as ...