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- Fu, Weiqi, et al. Show all 10 Authors
- Methods 2016 v.106 pp. 3-13
- high-throughput nucleotide sequencing; mutagenesis; nucleic acids; polypeptides; proteins
- ... Through iterative cycles of selection, amplification, and mutagenesis, in vitro selection provides the ability to isolate molecules of desired properties and function from large pools (libraries) of random molecules with as many as 10¹⁶ distinct species. This review, in recognition of a quarter of century of scientific discoveries made through in vitro selection, starts with a brief overview of th ...