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- Liu, Wenshe R., et al. Show all 10 Authors
- Chemical communications 2016 v.52 no.85 pp. 12606-12609
- chemical compounds; chemical reactions; epigenetics; fluorine; histones; lysine; peptides; phenylalanine; stop codon
- ... Fluorophenylalanines bearing 2–5 fluorine atoms at the phenyl ring have been genetically encoded by amber codon. Replacement of F59, a phenylalanine residue that is directly involved in interactions with trimethylated K9 of histone H3, in the Mpp8 chromodomain recombinantly with fluorophenylalanines significantly impairs the binding to a K9-trimethylated H3 peptide. ...