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- Maggio, Marcello, et al. Show all 7 Authors
- Clinical nutrition 2016 v.35 pp. 1512-1516
- caregivers; comorbidity; death; dementia; dysphagia; eating disorders; elderly; enteral feeding; guidelines; hospitals; malnutrition; mortality; nursing homes; patients; regression analysis; risk; Italy
- ... Despite guidelines, long-term enteral nutrition (EN) through percutaneous endoscopic gastrostomy (PEG) is often prescribed to older individuals with dementia and eating problems (refusal to eat or dysphagia). The aim of this prospective observational non-randomized un-blinded study was to assess the role of this procedure on risk of mortality.184 demented malnourished patients (58 M, age 82.2 ± 7. ...
- Maggio, Marcello, et al. Show all 11 Authors
- Nutrients 2016 v.8 no.4
- C-reactive protein; acute course; anti-inflammatory activity; inflammation; interleukin-1; interleukin-6; nutrients; nutritional intervention; omega-3 fatty acids; polyunsaturated fatty acids; sarcopenia; tumor necrosis factor-alpha; vitamin D; whey; whey protein
- ... Chronic activation of the inflammatory response, defined as inflammaging, is the key physio-pathological substrate for anabolic resistance, sarcopenia and frailty in older individuals. Nutrients can theoretically modulate this phenomenon. The underlying molecular mechanisms reducing the synthesis of pro-inflammatory mediators have been elucidated, particularly for vitamin D, n-3 polyunsaturated fa ...