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- Zhao, Jiamin, et al. Show all 10 Authors
- Biosensors & bioelectronics 2016 v.83 pp. 250-255
- DNA; biomedical research; biosensors; chimerism; fluorescence; hybridization probes; microRNA; neoplasm cells; neoplasms; nucleic acid hybridization; nucleotide sequences; quantitative analysis; signal transduction
- ... The accurate and quantitative analysis of microRNA (miRNA) expression is critical for biomedical research and clinical theranostics. In this study, we report a novel sensor for the sensitive detection of miRNA based on a duplex-specific nuclease (DSN)-assisted dual signal amplification strategy. A chimeric probe (DNA/2-OMe-RNA) that consists of a miRNA recognition DNA sequence and a Taqman probe h ...