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- Holst, Klaus K.; Scheike, Thomas H.; Hjelmborg, Jacob B.
- Computational statistics & data analysis 2016 v.93 pp. 324-335
- threshold models, etc ; death; etiology; family studies; heritability; prostatic neoplasms; risk; twins; Show all 8 Subjects
- ... Family studies provide an important tool for understanding etiology of diseases, with the key aim of discovering evidence of family aggregation and to determine if such aggregation can be attributed to genetic components. Heritability and concordance estimates are routinely calculated in twin studies of diseases, as a way of quantifying such genetic contribution. The endpoint in these studies are ...