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1. Molecular Cloning, Sequence, and Phylogenetic Analysis of T Helper 1 Cytokines of Pashmina Goats

Author:
Shebannavar, Sunil; Rasool, Thaha
Source:
Animal biotechnology 2015 v.26 no.2 pp. 120-129
ISSN:
1532-2378
Subject:
CD4-positive T-lymphocytes; amino acid sequences; amino acids; buffaloes; camels; cats; cattle; complementary DNA; dogs; goats; horses; humans; immune response; interferon-gamma; interleukin-12; interleukin-2; molecular cloning; nucleotide sequences; phylogeny; sequence alignment; sheep; swine
Abstract:
... Cytokines play an important role in regulation of immune responses either in health or disease. In the present study, the cDNAs encoding mature Interleukin (IL)-2, interferon gamma (IFN-γ), and IL-12 p35 and p40 of Pashmina goat were cloned and sequenced. The amino acid sequence was deduced from nucleotide sequence and compared with those available in GeneBank. Mature forms of goat IL-2, IFN-γ, IL ...
DOI:
10.1080/10495398.2013.877022