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You searched for: Publication year rev 7985-2015 Remove constraint Publication year rev: 7985-2015 Subject bioavailability Remove constraint Subject: bioavailability
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1. (−)-Epicatechin reduces blood pressure increase in high-fructose-fed rats: effects on the determinants of nitric oxide bioavailability

Author:
Maria C. Litterio; Marcela A. Vazquez Prieto; Ana M. Adamo; Rosana Elesgaray; Patricia I. Oteiza; Monica Galleano; Cesar G. Fraga
Source:
Journal of nutritional biochemistry 2015 v.26 pp. 745-751
ISSN:
0955-2863
Subject:
NAD(P)H oxidase (H2O2-forming); aorta; bioavailability; blood pressure; body weight; diet; drinking water; endothelial nitric oxide synthase; epicatechin; fructose; hypertension; metabolic syndrome; mitogen-activated protein kinase; models; nitric oxide; phosphorylation; rats; superoxide anion
Abstract:
... This work investigated the blood pressure (BP)-lowering effect of the flavanol (−)-epicatechin in a model of metabolic syndrome. Rats were fed a regular chow diet without (Control) or with 10% (w/v) fructose in the drinking water (high fructose, HF) for 8 weeks. A subgroup of the HF-fed rats was supplemented with (−)-epicatechin 20 mg/kg body weight (HF-EC). Dietary (−)-epicatechin reverted the in ...
DOI:
10.1016/j.jnutbio.2015.02.004

2. A Candidate Short-Term Toxicity Test Using Ampelisca brevicornis to Assess Sublethal Responses to Pharmaceuticals Bound to Marine Sediments

Author:
L. A. Maranho; L. B. Moreira; R. M. Baena-Nogueras; P. A. Lara-Martín; T. A. DelValls; M. L. Martín-Díaz
Source:
Archives of environmental contamination and toxicology 2015 v.68 no.2 pp. 237-258
ISSN:
0090-4341
Subject:
Amphipoda; DNA; DNA damage; acetylcholinesterase; adverse effects; antioxidants; bioassays; bioavailability; biomarkers; caffeine; environmental assessment; enzyme activity; genotoxicity; ibuprofen; indicator species; lipid peroxidation; marine sediments; metabolism; mortality; neurotoxicity; oxidative stress; propranolol; sediment contamination; toxicity testing
Abstract:
... Lethal and sublethal responses related to different phases of metabolism (phases I and II enzymatic activities), neurotoxicity (acetylcholinesterase activity), oxidative stress (lipid peroxidation and antioxidant enzyme activities), and genetic damage (DNA strand breaks) were analysed to assess the possible adverse effects of pharmaceuticals bound to marine sediments. The crustacean amphipod Ampel ...
DOI:
10.1007/s00244-014-0080-0

3. A Critical Review about the Health Risk Assessment of PAHs and Their Metabolites in Foods

Author:
Iria Yebra-Pimentel; Ricardo Fernández-González; Elena Martínez-Carballo; Jesús Simal-Gándara
Source:
Critical reviews in food science and nutrition 2015 v.55 no.10 pp. 1383-1405
ISSN:
1549-7852
Subject:
absorption; animal models; bioavailability; carcinogenesis; carcinogenicity; colorectal neoplasms; food intake; food science; foods; humans; ingestion; ingredients; intestinal absorption; laboratory animals; metabolism; metabolites; nutrition science; polycyclic aromatic hydrocarbons; risk; risk assessment; toxic substances
Abstract:
... Polycyclic aromatic hydrocarbons (PAHs) are a family of toxicants that are ubiquitous in the environment. These contaminants generate considerable interest, because some of them are highly carcinogenic in laboratory animals and have been implicated in breast, lung, and colon cancers in humans. Dietary intake of PAHs constitutes a major source of exposure in humans. Factors affecting the accumulati ...
DOI:
10.1080/10408398.2012.697497

4. A Fluorescent-Based HPLC Assay Using 4-Chloro-7-nitrobenzo-2-oxa-1, 3-diazole as Derivatization Agent for the Determination of Iron Bioavailability to Red Tide Phytoplankton

Author:
H. Hasegawa; K. Nakagawa; M. Azizur Rahman; M. Takemura; T. Maki; K. Naito; M. Mamunur Rahman
Source:
Chromatographia 2015 v.78 no.1-2 pp. 65-72
ISSN:
0009-5893
Subject:
Eutreptiella; Prymnesium; algal blooms; bioavailability; culture media; derivatization; fluorescence; high performance liquid chromatography; iron; nitrates; peptides; phosphates; phytoplankton; proteins; seawater
Abstract:
... A new fluorescent-based high-performance liquid chromatography (HPLC) assay using 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole (NBD-C1) was employed to determine iron (Fe) bioavailability to red tide phytoplankton in seawater. After growing four red tide species (Prymnesium parvum, Heterosigma akashiwo, Eutreptiella gymnastica, and Oltmannsiellopsis viridis) in f/2 artificial seawater under different F ...
DOI:
10.1007/s10337-014-2792-8

5. A Mechanistic Perspective on Process-Induced Changes in Glucosinolate Content in Brassica Vegetables: A Review

Author:
Probo Y. Nugrahedi; Ruud Verkerk; Budi Widianarko; Matthijs Dekker
Source:
Critical reviews in food science and nutrition 2015 v.55 no.6 pp. 823-838
ISSN:
1549-7852
Subject:
Brassica; bioavailability; blanching; boiling; cultural differences; fermentation; glucosinolates; health promotion; leaching; nutrients; nutrition science; palatability; phytochemicals; plant tissues; shelf life; steaming; stir frying; vegetables
Abstract:
... Brassica vegetables are consumed mostly after processing, which is expected to give beneficial effects on the vegetable properties, such as improved palatability and bioavailability of nutrients, or shelf life extension. But processing also results to various changes in the content of health promoting phytochemicals like glucosinolates. This paper reviews the effects of processing on the glucosino ...
DOI:
10.1080/10408398.2012.688076

6. A Survey of Plant Iron Content—A Semi-Systematic Review

Author:
Robert Ancuceanu; Mihaela Dinu; Marilena Viorica Hovaneţ; Adriana Iuliana Anghel; Carmen Violeta Popescu; Simona Negreş
Source:
Nutrients 2015 v.7 no.12 pp. 10320-10351
ISSN:
2072-6643
Subject:
Angiospermae; Gymnospermae; aerial parts; bark; bioavailability; data collection; ferns and fern allies; flowers; fruits; iron; iron deficiency anemia; leaves; roots; seeds; shoots; statistics; stems; surveys; wood
Abstract:
... Iron is an essential mineral nutrient for all living organisms, involved in a plurality of biological processes. Its deficit is the cause of the most common form of anemia in the world: iron deficiency anemia (IDA). This paper reviews iron content in various parts of 1228 plant species and its absorption from herbal products, based on data collected from the literature in a semi-systematic manner. ...
DOI:
10.3390/nu7125535
PubMed:
26690470
PubMed Central:
PMC4690087

7. A bioaccessible fraction of parboiled germinated brown rice exhibits a higher anti-inflammatory activity than that of brown rice

Author:
Siriporn Tuntipopipat; Chawanphat Muangnoi; Parunya Thiyajai; Warangkana Srichamnong; Somsri Charoenkiatkul; Kemika Praengam
Source:
Food & function 2015 v.6 no.5 pp. 1480-1488
ISSN:
2042-650X
Subject:
anti-inflammatory activity; bioactive compounds; bioavailability; brown rice; digestion; epithelial cells; ferulic acid; functional foods; gamma-aminobutyric acid; gamma-tocotrienol; human cell lines; humans; hydrogen peroxide; interleukin-1beta; interleukin-8; intestines; nutrients; oryzanol; p-coumaric acid; parboiling; secretion
Abstract:
... Parboiled germinated brown rice (PGBR) has been suggested as a functional food because it is relatively rich in a number of nutrients and health promoting compounds. Here we compared the bioaccessibility of several of the bioactive compounds in cooked PGBR and brown rice (BR) by simulating oral, gastric and small intestinal digestion. The uptake and retention of bioactive compounds from a bioacces ...
DOI:
10.1039/c4fo01194e

8. A biodynamic model predicting waterborne lead bioaccumulation in Gammarus pulex: Influence of water chemistry and in situ validation

Author:
N. Urien; E. Uher; E. Billoir; O. Geffard; L.C. Fechner; J.D. Lebrun
Source:
Environmental pollution 2015 v.203 pp. 22-30
ISSN:
0269-7491
Subject:
Gammarus pulex; aquatic organisms; bioaccumulation; bioavailability; calcium; environmental factors; hydrochemistry; kinetics; lead; models; prediction; watersheds; France
Abstract:
... Metals bioaccumulated in aquatic organisms are considered to be a good indicator of bioavailable metal contamination levels in freshwaters. However, bioaccumulation depends on the metal, the species, and the water chemistry that influences metal bioavailability. In the laboratory, a kinetic model was used to describe waterborne Pb bioaccumulated in Gammarus pulex. Uptake and elimination rate const ...
DOI:
10.1016/j.envpol.2015.03.045

9. A comparative study on the therapeutic effects of Silymarin and Silymarin-Loaded Solid Lipid Nanoparticles on D-GaIN/TNF-α-induced Liver Damage in Balb/c Mice

Author:
Mustafa Cengiz; H. Mehtap Kutlu; Dilek D. Burukoglu; Adnan Ayhancı
Source:
Food and chemical toxicology 2015 v.77 pp. 93-100
ISSN:
0278-6915
Subject:
antioxidant activity; apoptosis; bioavailability; drugs; gall bladder; hepatitis; hepatotoxicity; jaundice; lipids; liver; mice; nanoparticles; poisoning; proliferating cell nuclear antigen; scientists; silymarin; therapeutics; toxicology; toxins
Abstract:
... Nanostructure-mediated drug delivery is known to have a potential to improve drug bioavailability, apart from fostering release deviation of drug molecules and enabling precision drug targeting. Solid lipid nanoparticles (SLNs) have drawn great deal of the attention of scientists in finding a solution to minimize pharmaceutic limitations of the drugs used. Silymarin (Sm) has so far been used for t ...
DOI:
10.1016/j.fct.2014.12.011

10. A comprehensive review on the colorless carotenoids phytoene and phytofluene

Author:
Antonio J. Meléndez-Martínez; Paula Mapelli-Brahm; Ana Benítez-González; Carla M. Stinco
Source:
Archives of biochemistry and biophysics 2015 v.572 pp. 188-200
ISSN:
0003-9861
Subject:
animal models; bioactive properties; bioavailability; carrots; chemical structure; databases; epidemiological studies; food science; foods; humans; industry; lycopene; nutrition; oranges; physicochemical properties; tomatoes; Luxembourg
Abstract:
... Carotenoids and their derivatives are versatile isoprenoids involved in many varied actions, hence their importance in the agri-food industry, nutrition, health and other fields. All carotenoids are derived from the colorless carotenes phytoene and phytofluene, which are oddities among carotenoids due to their distinct chemical structure. They occur together with lycopene in tomato and other lycop ...
DOI:
10.1016/j.abb.2015.01.003

11. A critical evaluation of magnetic activated carbon’s potential for the remediation of sediment impacted by polycyclic aromatic hydrocarbons

Author:
Zhantao Han; Badruddeen Sani; Jarkko Akkanen; Sebastian Abel; Inna Nybom; Hrissi K. Karapanagioti; David Werner
Source:
Journal of hazardous materials 2015 v.286 pp. 41-47
ISSN:
0304-3894
Subject:
Lumbriculus variegatus; activated carbon; adsorbents; adverse effects; bioavailability; biochar; pollutants; polycyclic aromatic hydrocarbons; remediation; reproduction; sediments
Abstract:
... Addition of activated carbon (AC) or biochar (BC) to sediment to reduce the chemical and biological availability of organic contaminants is a promising in-situ remediation technology. But concerns about leaving the adsorbed pollutants in place motivate research into sorbent recovery methods. This study explores the use of magnetic sorbents. A coal-based magnetic activated carbon (MAC) was identifi ...
DOI:
10.1016/j.jhazmat.2014.12.030

12. A critical overview of the analytical approaches to the occurrence, the fate and the behavior of microplastics in the environment

Author:
Teresa Rocha-Santos; Armando C. Duarte
Source:
Trends in analytical chemistry 2015 v.65 pp. 47-53
ISSN:
0165-9936
Subject:
analytical methods; bags; bioavailability; chemical composition; cleaning agents; color; food packaging; physicochemical properties; plastics
Abstract:
... Plastics can be found in food packaging, shopping bags, and household items, such as toothbrushes and pens, and facial cleansers. Due to the high disposability and low recovery of discharged materials, plastics materials have become debris accumulating in the environment. Microplastics have a dimension <5 mm and possess physico-chemical properties (e.g., size, density, color and chemical compositi ...
DOI:
10.1016/j.trac.2014.10.011

13. A hyaluronic acid–pentamidine bioconjugate as a macrophage mediated drug targeting delivery system for the treatment of leishmaniasis

Author:
N. Micale; A. Piperno; N. Mahfoudh; U. Schurigt; M. Schultheis; P. G. Mineo; T. Schirmeister; A. Scala; G. Grassi
Source:
RSC advances 2015 v.5 no.116 pp. 95545-95550
ISSN:
2046-2069
Subject:
Leishmania major; adverse effects; antileishmanials; bioassays; bioavailability; bone marrow; drugs; hyaluronic acid; infectious diseases; leishmaniasis; macrophages; polymers; toxicity
Abstract:
... Leishmaniasis is still a serious public health problem worldwide, especially in tropical areas where this infectious disease is endemic. The most severe form of the disease (i.e. visceral) can claim victims if left untreated and the few accessible drugs have several drawbacks including major side effects and parenteral administration. In this context, the investigation of new delivery modalities w ...
DOI:
10.1039/c5ra18019h

14. A miniature porous aluminum oxide-based flow-cell for online water quality monitoring using bacterial sensor cells

Author:
Sharon Yagur-Kroll; Erik Schreuder; Colin J. Ingham; René Heideman; Rachel Rosen; Shimshon Belkin
Source:
Biosensors & bioelectronics 2015 v.64 pp. 625-632
ISSN:
0956-5663
Subject:
agar; aluminum oxide; bacteria; bioactive properties; bioavailability; bioluminescence; biosensors; effluents; fluorescence; freeze drying; monitoring; municipal wastewater; nutrients; porosity; toxic substances; water quality
Abstract:
... The use of live bacterial reporters as sensing entities in whole-cell biosensors allows the investigation of the biological effects of a tested sample, as well as the bioavailability of its components. Here we present a proof of concept for a new design for online continuous water monitoring flow-cell biosensor, incorporating recombinant reporter bacteria, engineered to generate an optical signal ...
DOI:
10.1016/j.bios.2014.09.076

15. A multi-element screening method to identify metal targets for blood biomonitoring in green sea turtles (Chelonia mydas)

Author:
C.A. Villa; S. Finlayson; C. Limpus; C. Gaus
Source:
Science of the total environment 2015 v.512-513 pp. 613-621
ISSN:
0048-9697
Subject:
Chelonia mydas; bioavailability; blood; environmental exposure; environmental factors; foraging; humans; marine environment; metals; monitoring; prioritization; quality control; quantitative analysis; rural areas; screening; space and time; toxicity; turtles; wildlife; Queensland
Abstract:
... Biomonitoring of blood is commonly used to identify and quantify occupational or environmental exposure to chemical contaminants. Increasingly, this technique has been applied to wildlife contaminant monitoring, including for green turtles, allowing for the non-lethal evaluation of chemical exposure in their nearshore environment. The sources, composition, bioavailability and toxicity of metals in ...
DOI:
10.1016/j.scitotenv.2014.11.100

16. A new organic matter fractionation methodology for organic wastes: Bioaccessibility and complexity characterization for treatment optimization

Author:
Julie Jimenez; Quentin Aemig; Nicolas Doussiet; Jean-Philippe Steyer; Sabine Houot; Dominique Patureau
Source:
Bioresource technology 2015 v.194 pp. 344-353
ISSN:
0960-8524
Subject:
bioavailability; dynamic models; fluorescence emission spectroscopy; fractionation; organic matter; organic wastes; principal component analysis
Abstract:
... Organic matter characterization is the starting point to describe organic waste treatments mechanisms and to propose their modeling. Two relevant characterization methodologies were frequently used in the literature based on chemical extractions and fluorescence spectroscopy. However, they could not be generalized to all the type of wastes because of the different molecules targeted. Consequently, ...
DOI:
10.1016/j.biortech.2015.07.037

17. A new speciation scheme of soil polycyclic aromatic hydrocarbons for risk assessment

Author:
Chen Wang; Lizhong Zhu; Chunlong Zhang
Source:
Journal of soils and sediments 2015 v.15 no.5 pp. 1139-1149
ISSN:
1439-0108
Subject:
bioaccumulation; bioavailability; correlation; desorption; environmental fate; fractionation; isotopes; octanol; organic soils; pollutants; polluted soils; polycyclic aromatic hydrocarbons; remediation; risk; risk assessment; saponification; soil organic matter; soil properties
Abstract:
... PURPOSE: The speciation of soil organic pollutants is of great importance for risk assessment and contaminant remediation, however, only few studies have attempted to develop a speciation scheme for a facilitated risk assessment. This paper postulates a pragmatic speciation scheme for the fractionation of soil polycyclic aromatic hydrocarbons (PAHs) that could correlate with their bioavailabilitie ...
DOI:
10.1007/s11368-015-1083-9

18. A novel in vitro method to model the fate of subcutaneously administered biopharmaceuticals and associated formulation components

Author:
Hanne M. Kinnunen; Vikas Sharma; Luis Rodrigo Contreras-Rojas; Yafei Yu; Chlöe Alleman; Alavattam Sreedhara; Stefan Fischer; Leslie Khawli; Stefan T. Yohe; Daniela Bumbaca; Thomas W. Patapoff; Ann L. Daugherty; Randall J. Mrsny
Source:
Journal of controlled release 2015 v.214 pp. 94-102
ISSN:
0168-3659
Subject:
animal models; animal use alternatives; bioavailability; biopharmaceuticals; blood; extracellular matrix; humans; hyaluronic acid; in vitro studies; injection site; insulin; lymph; monitoring; monoclonal antibodies; physicochemical properties; screening; subcutaneous injection
Abstract:
... Subcutaneous (SC) injection is becoming a more common route for the administration of biopharmaceuticals. Currently, there is no reliable in vitro method that can be used to anticipate the in vivo performance of a biopharmaceutical formulation intended for SC injection. Nor is there an animal model that can predict in vivo outcomes such as bioavailability in humans. We address this unmet need by t ...
DOI:
10.1016/j.jconrel.2015.07.016

19. A novel triazine-aryl-bis-indole derivative inhibits both phosphodiesterase IV and expression of cell adhesion molecules

Author:
Tanima Banerjee; Dipak Kar; Palakodety Radha Krishna; Sunchu Prabhakar; Rajesh Nomula; Venkata Satyanarayana Mallula; Hajari Ravindranath; Gattu Sridhar; Ramesh Adepu; Gourishetty Srikanth; Ulaganathan Mabalirajan; Balaram Ghosh; Parasuraman Jaisankar; Rakesh Johri; Dolonchapa Chakraborty; Vani Mishra; Jasmeet Kaur Chhabra; Mamta Shukla; Bhola Nath Paul; Santu Bandyopadhyay; Siddhartha Roy; Gangavaram V. M. Sharma; Arun Bandyopadhyay
Source:
RSC advances 2015 v.5 no.86 pp. 70271-70281
ISSN:
2046-2069
Subject:
adhesion; asthma; bioavailability; catechol; cyclic AMP; dose response; drugs; enzymes; epithelial cell adhesion molecule; epithelial cells; etiology; forskolin; humans; inflammation; inhibitory concentration 50; intercellular adhesion molecule-1; lungs; mice; moieties; neutrophils; pharmacokinetics; therapeutics; toxicity; tumor necrosis factor-alpha; umbilical veins; vascular cell adhesion molecules
Abstract:
... Asthma, like many inflammation related disorders, has a complex etiology. Drugs targeting multiple pathways may prove more efficacious in these complex disorders. Cyclic 3′,5′-adenosine monophosphate (cAMP) phosphodiesterase IV (PDE IV) is one of the validated targets in bronchial asthma and despite availability of some therapeutic molecules targeting PDE IV, molecules with better properties are d ...
DOI:
10.1039/c5ra11495k

20. A passive sampler based on solid phase microextraction (SPME) for sediment-associated organic pollutants: Comparing freely-dissolved concentration with bioaccumulation

Author:
Keith A. Maruya; Wenjian Lao; David Tsukada; Dario W. Diehl
Source:
Chemosphere 2015 v.137 pp. 192-197
ISSN:
0045-6535
Subject:
Bivalvia; DDT (pesticide); aquatic ecosystems; bioaccumulation; bioavailability; biotransformation; chlordane; estuaries; estuarine sediments; field experimentation; hydrophobicity; invertebrates; pollutants; polychlorinated biphenyls; polycyclic aromatic hydrocarbons; prediction; samplers; sediment contamination; solid phase microextraction; surface water; toxicity; uncertainty
Abstract:
... The elevated occurrence of hydrophobic organic chemicals (HOCs) such as polycyclic aromatic hydrocarbons (PAH), polychlorinated biphenyls (PCBs) and legacy organchlorine pesticides (e.g. chlordane and DDT) in estuarine sediments continues to poses challenges for maintaining the health of aquatic ecosystems. Current efforts to develop and apply protective, science-based sediment quality regulations ...
DOI:
10.1016/j.chemosphere.2015.07.042

21. A quantitative radioluminographic imaging method for evaluating lateral diffusion rates in skin

Author:
Allison K. Rush; Matthew A. Miller; Edward D. Smith; Gerald B. Kasting
Source:
Journal of controlled release 2015 v.216 pp. 1-8
ISSN:
0168-3659
Subject:
anti-infective agents; bioavailability; caffeine; carbon; diffusivity; image analysis; microorganisms; radiolabeling; radionuclides; surfactants; testosterone; zinc
Abstract:
... A method is presented for measuring the lateral diffusion coefficients of exogenously applied compounds on excised skin. The method involves sequential high resolution imaging of the spatial distribution of β-radiation associated with [¹⁴C]-labeled compounds to monitor the development of the concentration profile on the skin surface. It is exemplified by measurements made on three radiolabeled tes ...
DOI:
10.1016/j.jconrel.2015.07.032

22. A randomized trial of the effects of ezetimibe on the absorption of omega-3 fatty acids in cardiac disease patients: A pilot study

Author:
D.P. Blackwood; R.K. LaVallée; A. Al Busaidi; D.S. Jassal; G.N. Pierce
Source:
Clinical nutrition ESPEN 2015 v.10 no.5 pp. e155
ISSN:
2405-4577
Subject:
bioavailability; blood; cholesterol; cholesterol metabolism; dietary supplements; drugs; heart diseases; high density lipoprotein; intestinal absorption; intestines; linseed oil; low density lipoprotein; micelles; omega-3 fatty acids; patients; placebos; therapeutics; triacylglycerols
Abstract:
... Elevated levels of circulating omega-3 polyunsaturated fatty acids like alpha linolenic acid (ALA) may be beneficial for cardiovascular health. Circulating ALA concentrations are elevated dramatically by a cholesterol supplemented diet which increases ALA bioavailability through enhanced micelle formation in the intestines. Conversely, it is possible that drugs which inhibit cholesterol metabolism ...
DOI:
10.1016/j.clnesp.2015.07.002

23. A review of non-exhaustive chemical and bioavailability methods for the assessment of polycyclic aromatic hydrocarbons in soil

Author:
Vincent Lal; Cheng Peng; Jack Ng
Source:
Environmental technology & innovation 2015 v.4 pp. 159-167
ISSN:
2352-1864
Subject:
absorption; animal models; bioavailability; environmental law; gastrointestinal system; in vitro studies; polycyclic aromatic hydrocarbons; remediation; risk assessment; soil
Abstract:
... Current environmental regulations relating to risk assessment for contaminated sites are often set assuming that the contaminant is 100% bioavailable. It is therefore not surprising that remediation of contaminated sites is very expensive and maybe it is unrealistic to achieve a “remediated state” under current regulatory guidelines using existing technologies. In fact the reality is that only a p ...
DOI:
10.1016/j.eti.2015.07.001

24. A review of the ecotoxicological effects of nanowires

Author:
J. I. Kwak; Y.-J. An
Source:
International journal of environmental science and technology 2015 v.12 no.3 pp. 1163-1172
ISSN:
1735-1472
Subject:
antibacterial properties; bioavailability; chronic toxicity; cytotoxicity; ecotoxicology; genotoxicity; humans; ions; nanoparticles; nanowires
Abstract:
... We briefly reviewed the existing research on the ecotoxicity of nanowires and suggested directions for further study. Nanowires are technological innovations that can benefit humans. However, it is important to consider the effects of nanowires on the environment. Only a few studies have reported acute and chronic ecological toxicity of nanowires on aquatic and terrestrial organisms, and limited r ...
DOI:
10.1007/s13762-014-0727-4

25. A review of the effects of dietary organic acids fed to swine

Author:
Mocherla V A N Suiryanrayna; J V Ramana
Source:
Journal of animal science and biotechnology 2015 v.6 no.1 pp. 45
ISSN:
2049-1891
Subject:
animal production; antibacterial properties; antibiotics; bioavailability; biotechnology; dietary fiber; digestibility; energy; enterotoxigenic Escherichia coli; epithelium; excretion; feed intake; fermentation; gluconeogenesis; growth performance; hydrochloric acid; lactic acid; lipolysis; momentum; nitrogen; nutrient utilization; pH; pepsin; pepsinogen; pork; prebiotics; probiotics; proteolysis; weanlings; weight gain
Abstract:
... Animal production depends on nutrient utilization and if done there is an accelerated momentum towards growth with a low cost to feed ratio Public concern over the consumption of pork with antibiotic residues of the animals fed with antibiotic growth promoters (AGP) has paved the way to use other additives like herbs and their products, probiotics, prebiotics etc. Numerous feed additives are in vo ...
DOI:
10.1186/s40104-015-0042-z

26. A review: Using nanoparticles to enhance absorption and bioavailability of phenolic phytochemicals

Author:
Zheng Li; Hong Jiang; Changmou Xu; Liwei Gu
Source:
Food hydrocolloids 2015 v.43 pp. 153-164
ISSN:
0268-005X
Subject:
absorption barrier; bioactive compounds; bioactive properties; bioavailability; chronic diseases; coronary disease; diabetes; epithelial cells; gastrointestinal system; hydrocolloids; intestinal absorption; nanoparticles; neoplasms; phytopharmaceuticals; water solubility
Abstract:
... Phenolic phytochemicals have been of particular interests in food and pharmaceutical fields because they have potential to reduce the incidences of coronary heart disease, diabetes, cancers, and other chronic diseases. However, extremely low absorption rate of phenolic phytochemicals restricts their bioactivity in vivo. Such low absorption and bioavailability are due to their low water solubility, ...
DOI:
10.1016/j.foodhyd.2014.05.010

27. A risk assessment index for bioavailability of metals in sediments: Anzali International Wetland case study

Author:
Ahmad Jamshidi-Zanjani; Mohsen Saeedi; Loretta Y. Li
Source:
Environmental earth sciences 2015 v.73 no.5 pp. 2115-2126
ISSN:
1866-6280
Subject:
EDTA (chelating agent); ammonium acetate; bioavailability; cadmium; calcium chloride; case studies; chromium; coasts; copper; heavy metals; humans; lead; nickel; risk assessment; sediments; wetlands; zinc; Caspian Sea
Abstract:
... A new bioavailability/bioaccessibility risk assessment index (BRAI) was used to assess heavy metals’ (Cu, Cr, Zn, Pb, Ni, Cd) bioavailability/bioaccessibility of the aquatic sediments of Anzali International Wetland. This wetland, registered under the Ramsar Convention, is located along the southwestern part of the Caspian Sea coast. Heavy metal concentrations in the surface sediments of Anzali we ...
DOI:
10.1007/s12665-014-3562-5

28. A self-assembled nanoparticle platform based on poly(ethylene glycol)–diosgenin conjugates for co-delivery of anticancer drugs

Author:
Chunxiao Li; Lin Dai; Kefeng Liu; Lihong Deng; Tingting Pei; Jiandu Lei
Source:
RSC advances 2015 v.5 no.91 pp. 74828-74834
ISSN:
2046-2069
Subject:
antineoplastic agents; bioavailability; cancer therapy; diosgenin; drug delivery systems; nanoparticles; neoplasms; polyethylene glycol; solubility
Abstract:
... Diosgenin (DGN) is a steroidal saponin from a therapeutic herb. It is reported to be a kind of potential natural antitumor drug. However, clinical application of diosgenin in cancer therapy is limited due to undesirable pharmaceutical characteristics such as its consequently poor solubility and low bioavailability. Here we developed a nanoparticle platform based on poly(ethylene glycol)–diosgenin ...
DOI:
10.1039/c5ra15375a

29. A sensitive whole-cell biosensor for the simultaneous detection of a broad-spectrum of toxic heavy metal ions

Author:
S. Cerminati; F. C. Soncini; S. K. Checa
Source:
Chemical communications 2015 v.51 no.27 pp. 5917-5920
ISSN:
1364-548X
Subject:
bioavailability; biosensors; cadmium; chemical reactions; cost effectiveness; drinking water; fluorescence; gold; heavy metals; lead; mercury; metal ions; pollutants; toxicity
Abstract:
... Bacterial biosensors are simple, cost-effective and efficient analytical tools for detecting bioavailable heavy metals in the environment. This work presents the design, construction and calibration of a novel whole-cell fluorescent biosensory device that, simultaneously and with high sensitivity, reports the presence of toxic mercury, lead, cadmium and/or gold ions in aqueous samples. This bio-re ...
DOI:
10.1039/c5cc00981b

30. A shift toward a new holistic paradigm will help to preserve and better process grain products’ food structure for improving their health effects

Author:
Anthony Fardet
Source:
Food & function 2015 v.6 no.2 pp. 363-382
ISSN:
2042-650X
Subject:
Fabaceae; bioavailability; engineering; food composition; food matrix; foods; gastrointestinal system; germination; health effects assessments; nutrients; nutrition research; nuts; physicochemical properties; phytonutrients; rice; seeds; soaking
Abstract:
... This review aims at emphasizing the role played by physical characteristics and physico-chemical properties of the food matrix on the digestive and metabolic fate, and health effects of grain products. It is today obvious that the food matrix conditions the health effects of food products and that we are able to modify this matrix to control the digestive fate of foods, and the metabolic fate of n ...
DOI:
10.1039/c4fo00477a

31. A techno-economic analysis of industrial production of marine microalgae as a source of EPA and DHA-rich raw material for aquafeed: Research challenges and possibilities

Author:
Matilde S. Chauton; Kjell Inge Reitan; Niels Henrik Norsker; Ragnar Tveterås; Hans T. Kleivdal
Source:
Aquaculture 2015 v.436 pp. 95-103
ISSN:
0044-8486
Subject:
Geographical Locations; absorption; algae culture; aquaculture feeds; aquaculture industry; bioavailability; biomass production; bioreactors; biosynthesis; carbon dioxide; closed loop systems; cost effectiveness; dewatering; docosahexaenoic acid; economic sustainability; eicosapentaenoic acid; energy; fish oils; food webs; genetic engineering; interdisciplinary research; markets; microalgae; mutagenesis; nutrient uptake; nutrients; photosynthesis; production costs; production technology; raw materials; research and development; selection methods; supply chain
Abstract:
... The aquaculture industry needs a stable supply of feed resource materials in sufficient quantities and quality for future growth, in particular the fatty acids eicosapentaenoic acid (dha) and docosahexanoic acid (DHA) which so far have been ensured by inclusion of fish oil. About 70% of the available fish oil is being used in aquafeeds, but the global supply of fish oil is limited and emerging ome ...
DOI:
10.1016/j.aquaculture.2014.10.038

32. Absolute bioavailability and metabolism of aceclofenac in rats

Author:
Keumhan Noh; Beom Soo Shin; Kwang-il Kwon; Hwi-yeol Yun; Eunyoung Kim; Tae Cheon Jeong; Wonku Kang
Source:
Archives of pharmacal research 2015 v.38 no.1 pp. 68-72
ISSN:
0253-6269
Subject:
analgesia; analgesics; anti-inflammatory agents; aqueous solutions; bioavailability; blood; citrates; humans; intravenous injection; metabolites; osteoarthritis; pharmacokinetics; rats; rheumatoid arthritis; urea; water solubility
Abstract:
... Aceclofenac is one of the most popular analgesic and anti-inflammatory drugs used for the relief of pain, rheumatoid arthritis, and osteoarthritis. To date, no intravenous preparation of aceclofenac has been developed because of its poor water solubility. In this study, to investigate its absolute bioavailability and metabolism in rats, aceclofenac was dissolved in a sterile aqueous solution conta ...
DOI:
10.1007/s12272-014-0350-4

33. Absorption and Metabolism of Luteolin and Its Glycosides from the Extract of Chrysanthemum morifolium Flowers in Rats and Caco-2 Cells

Author:
Michiko Torii Yasuda; Kotone Fujita; Takahiro Hosoya; Shinjiro Imai; Kayoko Shimoi
Source:
Journal of agricultural and food chemistry 2015 v.63 no.35 pp. 7693-7699
ISSN:
0021-8561
Subject:
Chrysanthemum morifolium; absorption; bioavailability; body weight; flowers; glycosides; high performance liquid chromatography; human cell lines; humans; luteolin; mass spectrometry; metabolism; oral administration; rats
Abstract:
... To elucidate the bioavailability of luteolin and its glycosides in Chrysanthemum morifolium flowers, the absorption and metabolism of luteolin from them was investigated in rats and Caco-2 cells using HPLC and LC-MS. After oral administration of C. morifolium extract (1.7 g/kg body weight (bw), equivalent to 22.8 and 58.3 μmol/kg bw of luteolin and luteolin-7-O-glucoside, respectively) to rats, lu ...
DOI:
10.1021/acs.jafc.5b00232

34. Absorption and bioavailability of cefditoren pivoxil in hydrogels in vitro and in vivo

Author:
G. Venugopalarao; R. Lakshmipathy; Ganesh Gadamsetty; N.C. Sarada
Source:
Journal of Taibah University for Science 2015 v.9 no.1 pp. 1-6
ISSN:
1658-3655
Subject:
absorption; bioavailability; carboxymethylcellulose; cefditoren; drug formulations; drugs; half life; hydrogels; pharmacokinetics; porosity; sodium carbonate
Abstract:
... Superporous gastro-retentive cefditoren pivoxil tablets were prepared to improve the absorption and bioavailability of this drug and evaluated by varying the concentrations of carbopol and sodium carboxymethyl cellulose. The pre-compression and post-compression parameters were within acceptable pharmacopoeial limits. The swelling index indicates that formulations prepared with sodium carbonate hav ...
DOI:
10.1016/j.jtusci.2014.04.005

35. Absorption and bioavailability of nano-size reduced calcium citrate fortified milk powder in ovariectomized and ovariectomized-oteoporosis rats

Author:
Arezoo Erfanian; Hamed Mirhosseini; Babak Rasti; Mohd Hair-Bejo; Shuhaimi Bin Mustafa; Mohd Yazid Abd Manap
Source:
Journal of agricultural and food chemistry 2015 v.63 no.24 pp. 5795-5804
ISSN:
0021-8561
Subject:
Recommended Dietary Allowances; absorption; bioavailability; bone strength; calcium; citrates; docosahexaenoic acid; dried skim milk; eicosapentaenoic acid; in vivo studies; inulin; menopause; models; ovariectomy; rats; vitamins
Abstract:
... The aim of this study was to evaluate the effects of fortification and nano-size reduction on calcium absorption and bioavailability of milk powder formula in sham, ovariectomized, and ovariectomized-osteoporosis rats as a menopause and menopause-osteoporosis model. Skim milk powder and skim milk powder fortified with calcium citrate and the suitable doses of inulin, eicosapentaenoic acid (EPA) an ...
DOI:
10.1021/acs.jafc.5b01468

36. Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase‐treated broccoli sprout extract

Author:
Lauren L. Atwell; Anna Hsu; Carmen P. Wong; Jan F. Stevens; Deborah Bella; Tian‐Wei Yu; Clifford B. Pereira; Christiane V. Löhr; John Mark Christensen; Roderick H. Dashwood; David E. Williams; Jackilen Shannon; Emily Ho
Source:
Molecular nutrition & food research 2015 v.59 no.3 pp. 424-433
ISSN:
1613-4125
Subject:
absorption; adults; bioavailability; broccoli; chemoprevention; clinical trials; dietary nutrient sources; dietary supplements; dose response; glucoraphanin; heme oxygenase (biliverdin-producing); histone deacetylase; humans; metabolites; thioglucosidase; urine
Abstract:
... SCOPE: Sulforaphane (SFN), an isothiocyanate derived from crucifers, has numerous health benefits. SFN bioavailability from dietary sources is a critical determinant of its efficacy in humans. A key factor in SFN absorption is the release of SFN from its glucosinolate precursor, glucoraphanin, by myrosinase. Dietary supplements are used in clinical trials to deliver consistent SFN doses, but myros ...
DOI:
10.1002/mnfr.201400674
PubMed:
25522265
PubMed Central:
PMC4394840

37. Absorption mechanism of whey-protein-delivered curcumin using Caco-2 cell monolayers

Author:
Ming Li; Jie Cui; Michael O. Ngadi; Ying Ma
Source:
Food chemistry 2015 v.180 pp. 48-54
ISSN:
0308-8146
Subject:
absorption; beta-lactoglobulin; bioavailability; curcumin; digestion; gastrointestinal system; human cell lines; models; nanoemulsions; pH; pepsin; permeability; polyacrylamide gel electrophoresis; trypsin; water solubility
Abstract:
... Curcumin (CCM) is a bioactive polyphenolic compound that suffers a low bioavailability because of its low water solubility. In this work β-lactoglobulin (β-Lg) and nanoemulsion were used as carriers to deliver curcumin. The pH stability of β-Lg–CCM was investigated. The digestion of β-Lg–CCM and the nanoemulsion was studied using an in vitro gastrointestinal model. The effect of different carriers ...
DOI:
10.1016/j.foodchem.2015.01.132

38. Acaricidal effects of fluazuron (2.5 mg/kg) and a combination of fluazuron (1.6 mg/kg) + ivermectin (0.63 mg/kg), administered at different routes, against Rhipicephalus (Boophilus) microplus parasitizing cattle

Author:
Lucas Vinicius Costa Gomes; Welber Daniel Zanetti Lopes; Breno Cayeiro Cruz; Weslen Fabricio Teixeira; Gustavo Felippelli; Willian G. Maciel; Murilo Abud Bichuette; Maycon A. Ruivo; Marcos Henrique Alcantara Colli; Rafael Silveira Carvalho; Antonio Campanha Martinez; Vando Edésio Soares; Alvimar José da Costa
Source:
Experimental parasitology 2015 v.153 pp. 22-28
ISSN:
0014-4894
Subject:
Rhipicephalus microplus; bioavailability; cattle; ivermectin; parasitism; pharmacokinetics; sodium chloride; ticks
Abstract:
... The present study aimed to evaluate the acaricidal efficacy of fluazuron (2.5 mg/kg), administered as a pour-on, in comparison to an injectable formulation containing fluazuron (1.6 mg/kg) + ivermectin (0.63 mg/kg), against Rhipicephalus (Boophilus) microplus in naturally and experimentally infested cattle. Two studies were conducted with different tick strains, one with artificial infestations (S ...
DOI:
10.1016/j.exppara.2015.02.004

39. Access to trifluoromethylated 4-alkoxy-2-pyrones, pyridones and quinolones

Author:
Sarah L. Clarke; Gerard P. McGlacken
Source:
Tetrahedron 2015 v.71 pp. 2906-2913
ISSN:
0040-4020
Subject:
bioactive properties; bioavailability; chemical reactions; chemical structure; hydrophobicity; quinolones
Abstract:
... 2-Pyrones, pyridones and quinolones represent classes of molecules with remarkable and diverse biological activity. The introduction of a trifluoromethyl group to a molecule can have dramatic and beneficial effects in terms of lipophilicity and bioavailability. Herein we report a route to afford a library of novel trifluoromethylated 2-pyrones, 2-pyridones and a 2-quinolone in moderate to good yie ...
DOI:
10.1016/j.tet.2015.03.061

40. Accumulation Dynamics and Acute Toxicity of Silver Nanoparticles to Daphnia magna and Lumbriculus variegatus: Implications for Metal Modeling Approaches

Author:
Khan Farhan R.; Paul Kai B.; Dybowska Agnieszka D.; Valsami-Jones Eugenia; Lead Jamie R.; Stone Vicki; Fernandes Teresa F.
Source:
Environmental Science & Technology 2015 v.49 no.7 pp. 4389-4397
ISSN:
1520-5851
Subject:
Daphnia magna; Lumbriculus variegatus; acute toxicity; bioaccumulation; bioavailability; ecotoxicology; feeding behavior; ingestion; ligands; models; nanoparticles; nanosilver; silver; trace elements
Abstract:
... Frameworks commonly used in trace metal ecotoxicology (e.g., biotic ligand model (BLM) and tissue residue approach (TRA)) are based on the established link between uptake, accumulation and toxicity, but similar relationships remain unverified for metal-containing nanoparticles (NPs). The present study aimed to (i) characterize the bioaccumulation dynamics of PVP-, PEG-, and citrate-AgNPs, in compa ...
DOI:
10.1021/es506124x

41. Accumulation of copper and zinc fractions in vineyard soil in the mid-western region of Santa Catarina, Brazil

Author:
Rafael da Rosa Couto; Lucas Benedet; Jucinei José Comin; Paulo Belli Filho; Sérgio Roberto Martins; Luciano Colpo Gatiboni; Marilice Radetski; Cassio Marques de Valois; Vítor Gabriel Ambrosini; Gustavo Brunetto
Source:
Environmental earth sciences 2015 v.73 no.10 pp. 6379-6386
ISSN:
1866-6280
Subject:
Vitis; bioavailability; chemical analysis; copper; forests; fractionation; fungicides; minerals; organic matter; physicochemical properties; soil profiles; toxicity; vineyard soils; vineyards; zinc; Brazil
Abstract:
... The application of fungicides to grapevines can cause the accumulation of Cu and Zn fractions in soil and increase their bioavailability and toxicity for plants. This study evaluated the accumulation and distribution of Cu and Zn fractions in the soil profile of a vineyard. In January 2012, stratified samples were collected from a 95-year-old vineyard and from a forest, which was used as a referen ...
DOI:
10.1007/s12665-014-3861-x

42. Accumulation of silver by Fucus spp. (Phaeophyceae) and its toxicity to Fucus ceranoides under different salinity regimes

Author:
K. Ramesh; S. Berry; M. T. Brown
Source:
Ecotoxicology 2015 v.24 no.6 pp. 1250-1258
ISSN:
0963-9292
Subject:
Fucus ceranoides; abiotic stress; bioavailability; estuaries; euryhaline species; growth retardation; lipid peroxidation; macroalgae; mining; pollution; reactive oxygen species; salinity; sediments; silver; stress response; toxicity; watersheds; England
Abstract:
... Metals constitute an important group of abiotic stressors that elicit stress responses in marine algae that include the production of reactive oxygen species (ROS). Silver (Ag) is a highly toxic metal to organisms but despite this there are relatively few studies on how it affects marine macroalgae (seaweeds). In a landmark study published in 1977 the first information was provided on the accumula ...
DOI:
10.1007/s10646-015-1495-8

43. Accumulation of trace metals in sediments in a Mediterranean Lagoon: Usefulness of metal sediment fractionation and elutriate toxicity assessment

Author:
Noureddine Zaaboub; Maria Virgínia Alves Martins; Amel Dhib; Béchir Béjaoui; François Galgani; Monia El Bour; Lotfi Aleya
Source:
Environmental pollution 2015 v.207 pp. 226-237
ISSN:
0269-7491
Subject:
acid volatile sulfides; bioassays; bioavailability; cadmium; chromium; copper; fractionation; lead; nickel; redox potential; sediments; toxicity; zinc; Tunisia
Abstract:
... The authors investigated sediment quality in Bizerte Lagoon (Tunisia) focusing on geochemical characteristics, metal sediment fractionation and elutriate toxicity assessment. Nickel, Cu, Zn, Pb, Cr and Cd partitioning in sediments was studied; accumulation and bioavailability were elucidated using enrichment factors, sequential extractions, redox potential, acid volatile sulfide and biotest proced ...
DOI:
10.1016/j.envpol.2015.09.033

44. Accumulations of copper in apple orchard soils: distribution and availability in soil aggregate fractions

Author:
Quan-Ying Wang; Jing-Shuang Liu; Yang Wang; Hong-Wen Yu
Source:
Journal of soils and sediments 2015 v.15 no.5 pp. 1075-1082
ISSN:
1439-0108
Subject:
apples; bioavailability; copper; fungicides; heavy metals; orchard soils; orchards; sieving; soil sampling
Abstract:
... PURPOSE: The particle fractions of soil influence the retention and availability of heavy metal. However, the accumulations of Cu in aggregate size fractions of apple orchard soils due to the long-term application of Cu-based fungicides remain poorly understood. This study aimed to investigate the distribution and availability of Cu in various aggregate fractions of soils from different aged apple ...
DOI:
10.1007/s11368-015-1065-y

45. Aceclofenac nanocrystals for improved dissolution: influence of polymeric stabilizers

Author:
Satyanarayan Pattnaik; Kalpana Swain; Jupally Venkateswar Rao; Talla Varun; K. Baikuntha Prusty; Sanjeev Kumar Subudhi
Source:
RSC advances 2015 v.5 no.112 pp. 91960-91965
ISSN:
2046-2069
Subject:
X-ray diffraction; bioavailability; drugs; engineering; intestinal absorption; intestines; lipophilicity; methylcellulose; nanocrystals; particle size; particle size distribution; permeability; polymers; scanning electron microscopy; solubility; stabilizers
Abstract:
... With the increasingly lipophilic nature of candidate drugs, solubility and dissolution rates have become the limiting factors that affect bioavailability of oral and parenteral formulations. The purpose of the study is to improve the dissolution rate of aceclofenac through a nanonization technique. In the present work, particle engineering was carried out to obtain pure drug nanocrystals of aceclo ...
DOI:
10.1039/c5ra20411a

46. Acute phytotoxicity of seven metals alone and in mixture: Are Italian soil threshold concentrations suitable for plant protection?

Author:
Diego Baderna; Eleonora Lomazzi; Alberto Pogliaghi; Gianluca Ciaccia; Marco Lodi; Emilio Benfenati
Source:
Environmental Research 2015 v.140 pp. 102-111
ISSN:
0013-9351
Subject:
Cucumis sativus; Lepidium sativum; Sorghum bicolor subsp. bicolor; arsenic; bioavailability; cadmium; chromium; cucumbers; ecotoxicology; fruits; germination; human nutrition; humans; inhibitory concentration 50; lead; mercury; models; nickel; phytotoxicity; plant protection; plants (botany); pollutants; rice; rural areas; seeds; soil; soil formation; soil pollution; zinc
Abstract:
... Metals can pollute soils in both urban and rural areas with severe impacts on the health of humans, plants and animals living there. Information on metal toxicity is therefore important for ecotoxicology. This study investigated the phytotoxicity of different metals frequently found as pollutants in soils: arsenic, cadmium, chromium, lead, mercury, nickel and zinc. Cucumber (Cucumis sativus), sorg ...
DOI:
10.1016/j.envres.2015.03.023

47. Acute supplementation with blackcurrant extracts modulates cognitive functioning and inhibits monoamine oxidase-B in healthy young adults

Author:
Anthony W. Watson; Crystal F. Haskell-Ramsay; David O. Kennedy; Janine M. Cooney; Tania Trower; Arjan Scheepens
Source:
Journal of functional foods 2015 v.17 pp. 524-539
ISSN:
1756-4646
Subject:
amine oxidase (flavin-containing); animal models; anthocyanins; bioavailability; black currants; central nervous system diseases; cognition; cross-over studies; cultivars; emotions; humans; neuroprotective effect; polyphenols; young adults
Abstract:
... The consumption of berry fruits engenders a number of benefits in animal models, including improvements in cognitive performance, slowing of cognitive decline during natural ageing, and neuroprotection. These findings, along with limited human epidemiological evidence, suggest a potential role for the consumption of berry fruit polyphenols in improving human cognitive performance. The current stud ...
DOI:
10.1016/j.jff.2015.06.005

48. Acute toxicity of binary and ternary mixtures of Cd, Cu, and Zn to Daphnia magna

Author:
Joseph S. Meyer; James F. Ranville; Mandee Pontasch; Joseph W. Gorsuch; William J. Adams
Source:
Environmental toxicology and chemistry 2015 v.34 no.4 pp. 799-808
ISSN:
0730-7268
Subject:
Daphnia magna; acute toxicity; bioavailability; cadmium; copper; dissolved organic carbon; fulvic acids; models; neonates; rivers; toxicity testing; zinc
Abstract:
... Standard static‐exposure acute lethality tests were conducted with Daphnia magna neonates exposed to binary or ternary mixtures of Cd, Cu, and Zn in moderately hard reconstituted water that contained 3 mg dissolved organic carbon/L added as Suwannee River fulvic acid. These experiments were conducted to test for additive toxicity (i.e., the response to the mixture can be predicted by combining the ...
DOI:
10.1002/etc.2787

49. Additive, dominant parental effects control the inheritance of grain cadmium accumulation in hybrid rice

Author:
Wenyuan Yao; Liang Sun; Hao Zhou; Fei Yang; Donghai Mao; Jiurong Wang; Lianghui Chen; Guoyu Zhang; Jinpeng Dai; Guoying Xiao; Caiyan Chen
Source:
Molecular breeding 2015 v.35 no.1 pp. 246
ISSN:
1380-3743
Subject:
additive effect; additive gene effects; bioavailability; breeding lines; cadmium; crossing; cultivars; cytoplasmic male sterility; diallel analysis; general combining ability; grain crops; heading; heritability; hybrids; inheritance (genetics); parents; restorer lines; rice; specific combining ability
Abstract:
... Rice, a staple crop for more than half of the world’s population, takes up and accumulates more cadmium (Cd) than do other cereal crops (Chaney et al. in Z Naturforsch C 60(3–4):190–198, 2005). Rice is the leading source of dietary Cd for people who consume rice as their main food resource. A low grain Cd (GCd) concentration is a highly desirable trait for food safety. Low GCd is a top priority ta ...
DOI:
10.1007/s11032-015-0246-0

50. Adhesion and spreading of osteoblast-like cells on surfaces coated with laminin-derived bioactive core peptides

Author:
In-Sung Yeo; Seung-Ki Min; Hyun Ki Kang; Taek-Ka Kwon; Sung Youn Jung; Byung-Moo Min
Source:
Data in Brief 2015 v.5 pp. 411-415
ISSN:
2352-3409
Subject:
adhesion; amino acids; bioavailability; bone formation; drugs; humans; laminin; medicine; molecular weight; peptides; therapeutics
Abstract:
... Functional peptides are attractive as novel therapeutic reagents because their amino acid sequences are flexible in adopting and mimicking the local functional features of proteins. These peptides are of low molecular weight, synthetically versatile and inexpensive to produce, suggesting that they can be used as drug targeting, potent, stable and bioavailable agents. A short bioactive peptide is e ...
DOI:
10.1016/j.dib.2015.09.032