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Oriental traditional medicine; Salvia miltiorrhiza; T-lymphocytes; anti-allergic agents; antibacterial properties; calcium; enzyme-linked immunosorbent assay; hepatitis; immunoblotting; inflammation; mast cells; mice; mitogen-activated protein kinase; neoplasms; non-specific protein-tyrosine kinase; phospholipases; phosphorylation; precipitin tests; prostaglandins; signal transduction; transcription factor NF-kappa B
Abstract:
... 15,16-Dihydrotanshinone I (DHT-I), isolated from the dried root of Salvia miltiorrhiza Bung, which is traditionally used to treat cardiovascular and inflammatory diseases agent in Chinese medicine. DHT-I has been reported to have a broad range of biological activities, including antibacterial activity, and has been used to treat circulatory disorders, hepatitis, inflammation, cancer, and neurodege ...
... Brominated furanone and epigallocatechin gallate (EGCG) are naturally occurring polyphenolic compounds that can be derived from sources such as Delisea pulchra algae and green tea, respectively. These compounds may have potential health benefits and antimicrobial properties. Biofilm formation and bacterial motility are virulence factors that seem to be involved in the autoinducer 2 (AI-2)-mediated ...
... In an attempt to find a new class of heterocyclic bio-active agents, a series of novel 3-(1-phenyl-4-((2-(4-arylthiazol-2-yl)hydrazono)methyl)-1H-pyrazol-3-yl)-2H-chromen-2-one derivatives (5a–l) have been synthesized efficiently both quantitatively and qualitatively via a three-component one-pot manner by Hantzsch condensation. Structures of all the newly synthesized compounds were established by ...
... In the bone tissue engineering field, there is a growing interest in the application of bioactive glass scaffolds (45S5Bioglass®) due to their bone bonding ability, osteoconductivity and osteoinductivity. However, such scaffolds still lack some of the required functionalities to enable the successful formation of new bone, e.g. effective antibacterial properties. A large number of studies suggest ...
... A series of 6-tosyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide analogues are synthesized by conventional techniques and characterized by elemental analysis, IR, MS,¹H, and¹³C NMR. These are tested for their antibacterial activity against Bacillus subtilis (abbreviated as BS), Staphylococcus aureus (abbreviated as SA), and Escherichia coli (abbreviated as EC). The synthesized compounds a ...
The purpose of this study was to compare the antibacterial activity of 60% ethanol and extracts distilled water from red pitaya (Hylocereus polyrhizus) peel to bacteria Staphylococcus aureus and Escherichia coli. The treatment used was the concentration of the extract with some dilution treatment. Antibacterial activity test performed using paper di ...
... Screening Ageratum conyzoides L. fraction for antibacterial activity using thin layer chromatography bioautography have been done. The method is based on thin-layer chromatography–direct bioautography of Ageratum conyzoides chloroform fraction. The aim of study to determine the antibacterial activity of chloroform Ageratum conyzoides L. fraction in TLC bioautography. Extraction was done by macerat ...
... Evaluation of natural products as a safe and effective antimicrobial agent is a scientific strategy to treat the drugresistant pathogens.Fennel(FoeniculumvulgareMill) is an herbal plant that has an active in gredient which is one of its benefit sasan antibacterial material. In thisstudy,water extract of fennel fruit determined the antibacterial activity against Vibrio harveyi and Vibrio alginolyti ...
... The aims of this study was to determine the characteristics, composition and antimicrobial activity of essential oils of local Indonesian red ginger and red galangal against four pathogenic and food spoilage bacteria, which were B.cereus ATCC 10876, E. coli ATCC 25922, S. typhimuriumATCC 14028, and P. aeruginosa ATCC 27853. Analysis of physicochemical characteristics was carried outin accordance w ...
... The emergence of multidrug-resistant Mycobacterium tuberculosis strains has led to the development of new antituberculous agents. In this context, antimicrobial targeting proteins to the cell membrane are interesting due to the avoidance of the plasma membrane permeation. Through this study, the antimicrobial activity, cellular toxicity, as well as the effect on the mycobacterial cell membrane ATP ...
... Seven new nonadecaketides (1–7), lobophorols A–C, lobophopyranones A and B, and lobophorones A and B, along with the first naturally occurring related metabolites (8–10), were isolated from specimens of Lobophora variegata collected from the Canary Islands. Their structures were determined by extensive spectroscopic methods. In addition, an insight into the biosynthesis of these compounds on the b ...
... Two new oxaphenalenone dimers, talaromycesone A (1) and talaromycesone B (2), and a new isopentenyl xanthenone, talaroxanthenone (3), together with six known diphenyl ether derivatives, e.g., Δ¹′,³′,-1′-dehydroxypenicillide (4), 1′,2′-dehydropenicillide (5), vermixocin A (6), vermixocin B (7), 3′-methoxy-1′2′-dehydropenicillide (8), and AS-186c (9), were isolated from the culture broth and mycelia ...
... Silver nanoparticle (AgNP) synthesis and characterization is an area of vast interest due to their broader application in the fields of science and technology and medicine. Plants are an attractive source for AgNP synthesis because of its ability to produce a wide range of secondary metabolites with strong reducing potentials. Thus, the present study describes the synthesis of AgNPs using aqueous ...
... Flow cytometry exactly discriminated three subpopulations, i.e., viable, damage and sublethal cells of L. monocytogenes, S. aureus and E. coli when treated at their MIC values. Purity gum ultra (PGU) a large molecule surfactant-based CO nanoemulsion exerted significant impact on cellular subpopulations of L. monocytogenes and S. aureus, with more membrane-damaged cells. On the other hand, when com ...
Priscila L.L. Freire; Thayza C.M. Stamford; Allan J.R. Albuquerque; Fabio C. Sampaio; Horacinna M.M. Cavalcante; Rui O. Macedo; André Galembeck; Miguel A.P. Flores; Aronita Rosenblatt
... This study aimed to evaluate the cytotoxicity and bactericidal properties of four silver nanoparticle (AgNP) colloids and their ability to inhibit Streptococcus mutans biofilm formation on dental enamel. The cytotoxicity of AgNPs was evaluated based on signs of vascular change on the chorioallantoic membrane using the hen's egg test (HET-CAM). Bactericidal properties and inhibition of S. mutans bi ...
... In our continuing pursuit to discover natural products and natural product-based compounds to control the bacterial species Flavobacterium columnare which causes columnaris disease in channel catfish (Ictalurus punctatus), we synthesized flavone and chalcone analogs, and evaluated these compounds, along with flavonoids from natural sources, for antibacterial activities against two isolates of F. c ...
... Studies with facultative intracellular bacterial pathogens have shown that evaluation of the bactericidal activity of antimicrobial agents against intracellular bacteria is more closely associated with in vivo efficacy than traditional in vitro susceptibility testing. The objective of this study was to determine the relative activity of 10 antimicrobial agents against intracellular Rhodococcus equ ...
Xanthomonas oryzae pv. oryzae; antibacterial properties; field experimentation; leaf blight; microbial growth; minimum inhibitory concentration; rice; zinc; China
Abstract:
... Bacterial leaf blight of rice (BLB), caused by Xanthomonas oryzae pv oryzae, is one of the most serious bacterial diseases in China. Presently, bismerthiazol has been the major bactericide for the control of BLB, however, bismerthiazol‐resistant strains of X. oryzae pv. oryzae have appeared in the field in China. Zinc thiazole is a novel bactericide with strong antibacterial activity against Xanth ...
... Most of the magnesium (Mg) alloys possess excellent biocompatibility, mechanical properties and biodegradability in orthopedic applications. However, these alloys may suffer from bacterial infections due to their insufficient antibacterial capability. In order to reduce the post-surgical infections, a series of biocompatible Mg–1Ca–0.5Sr–xZn (x = 0, 2, 4, 6) alloys were fabricated with the additio ...
... Three new terpene metabolites (1–3) were isolated from the marine sponge Clathria gombawuiensis collected from Korean waters. On the basis of the results of combined spectroscopic analyses, the structures of phorone B (1) and ansellone C (2) were determined to be the sesterterpenes of the phorone and ansellone classes, respectively, whereas the saponin gombaside A (3) was a nortriterpene sodium O- ...
... Pure chitosan and its zinc oxide composite coatings were applied on microfibriller cellulose mat (MCM) to prepare chitosan coated microfibriller cellulose (Chi-MCM) and zinc oxide/chitosan coated microfibriller cellulose (ZnO/Chi-MCM), respectively. X-ray diffraction (XRD), and scanning electron microscopy (SEM), were used to characterize the samples in this study. SEM images showed that dense chi ...
... The winemaking grape pomaces are rich in bioactive phytochemicals and dietary fibre (DF). DFs are phenolic-rich DF matrix and are dietary supplement with benefits on human health. As a result of the increased attention to sustainability of winemaking by-products, efforts have been made to use grape pomace in different bio-industries. In this review, we summarize the existing knowledge on the bioac ...
... Here, we report on the development of advanced biopolymer-coated drug-releasing implants based on titanium (Ti) featuring titania nanotubes (TNTs) on its surface. These TNT arrays were fabricated on the Ti surface by electrochemical anodization, followed by the loading and release of a model antibiotic drug, gentamicin. The osteoblastic adhesion and antibacterial properties of these TNT–Ti samples ...
... The development of coupled semiconductor oxides has led to significant advances in photocatalytic functional materials. In this article, we report the preparation of a nano-spherical InCrO₄-loaded TiO₂ photocatalyst by a simple co-precipitation method. The InCrO₄–TiO₂ (ICT) nanomaterial was characterized using XRD, SEM with EDX, FT-IR, FT-Raman and PL analysis. The photocatalytic activity of InCrO ...
... Helicobacter pylori is a common human pathogen infecting about 30 % of children and 60 % of adults worldwide. It is responsible for diseases such as gastritis, peptic ulcer and gastric cancer. H. pylori treatment based on antibiotics with proton pump inhibitor, but therapy failure is shown to be higher than 20 % and is essentially due to an increasing in prevalence of antibiotic-resistant bacteria ...
... This paper presents a facile method for preparing Ag nanoparticle (NP)-loaded superamphiphobic surfaces on an Al substrate with efficient anticorrosion and antibacterial properties. A hierarchical steplike microstructure with nanopores is fabricated on an Al surface through facile chemical etching and anodization; subsequent fluorination confers superhydrophobic and superoleophobic properties to t ...
Fourier transform infrared spectroscopy; amides; antibacterial properties; aqueous solutions; cationic surfactants; chemical structure; chlorides; electrical conductivity; electrospray ionization mass spectrometry; nuclear magnetic resonance spectroscopy; surface tension; temperature; thermodynamics
Abstract:
... A series of novel cationic surfactants, N-alkylcaramoylmethyl-N-[2-(2-phenoxyacetamido)-ethyl]-N,N-dimethylammonium chloride, were synthesized and their chemical structures were characterized using ¹H-NMR, ¹³C-NMR, ESI-MS and FT-IR. Their aggregation behaviours in aqueous solution were systematically investigated by surface tension and electrical conductivity methods. It was found that the surfact ...
Escherichia coli; Staphylococcus aureus; analysis of variance; antibacterial properties; chloramphenicol; ethyl acetate; hexane; methanol; oysters; placenta; Indonesia
Abstract:
...
Penelitian ini bertujuan menguji aktivitas antibakteri ekstrak kerang pisau dan kerang simping dalam menghambat pertumbuhan bakteri uji berdasarkan zona jernih yang terbentuk dan menentukan jenis ekstrak kerang yang paling optimal dalam menghambat pertumbuhan bakteri uji. Kerang pisau yang diperoleh dari Pantai Talang Siring Madura dan kerang simping yang diperoleh dari Lamongan diekstrak denga ...
chemical reactions; hydrogen peroxide; catalysts; mannitol; chemical structure; antibacterial properties
Abstract:
... We report a newly developed synthesis of a number of alditol thiacrowns using an eco-friendly and versatile two-step strategy: the regioselective thioallyletherification of a polyhydroxylated alditol followed by a ring closing metathesis using the Grubbs second generation catalyst. This approach allows a series of target thiacrown products to be obtained in acceptable to good yields, from the corr ...
... Zinc oxide nanoparticles (ZnO nps) are known to be effective against a wide array of microorganisms. At nanoscale, they have higher toxicity and they need to be rendered less toxic and more biocompatible. To achieve this, ZnO nps were incorporated in nanohydrogel particles made out of sodium alginate/gum acacia and cross-linker glutaraldehyde in order to ensure their gradual and sustained release ...
... Herbal medicine requires searching for new sources with antimicrobial activity. Alkanna sp. (Boraginaceae) is widely used in medicine due to detoxification and antibacterial effects. The aim of this study was to obtain Alkanna orientalis (L.) Boiss. plant callus extracts, to investigate antimicrobial activity of extracts against bacteria and yeast and to reveal responsible mechanisms. Callus tissu ...
... BACKGROUND: Plants are rich source of chemical compounds that are used to accomplish biological activity. Indigenously crude extracts of plants are widely used as herbal medicine for the treatment of infections by people of different ethnic groups. The present investigation was carried out to evaluate the biological potential of Alkanna tinctoria leaves extract from district Charsadda, Pakistan ag ...
... The enzyme alpha amylase was used as the sole reducing and capping agent for the synthesis of TiO2 nanoparticles. The biosynthesized nanoparticles were characterized by X-ray diffraction (XRD) and transmission electron microscopic (TEM) methods. The XRD data confirms the monophasic crystalline nature of the nanoparticles formed. TEM data shows that the morphology of nanoparticles depends upon the ...
... Marine organisms are seen as a source of novel drugs and the discovery of new pharmaceutical is increasingly in demand. Cyanobacteria are regarded as a potential target for this as antibacterial, antiviral, antifungal, algicide and cytotoxic activities have been reported in these organisms. They have been identified as a new and rich source of bioactive compounds belonging to diversified groups. R ...
... AIMS: The aims of study were to examine the antibacterial potential of two commercial essential oils (EOs) from coriander (Coriandrum sativum L.) and thyme (Thymus vulgaris L.) against vaginal clinical strains of bacteria and yeast and their chemical composition. METHODS AND RESULTS: Antimicrobial activities of commercial essential oils were determined using macro‐diffusion (disc, well) and micro‐ ...
... Antibacterial activity of methanol and ethanol extracts of vegetative and reproductive thalli of the liverwort Pellia endiviifolia from eastern Himalaya were tested against Staphylococcus aureus (ATCC 25923), Shigella dysenteriae (ATCC 9361), Enterobacter cloacae (ATCC 13047), and Serratia marcescens (ATCC 13880) strains by well diffusion assay, minimum inhibitory concentration, and minimum bacter ...
... Bryophytes, phylogentically placed between alga and pteridophytes, lacks mechanical protection but protects itself form the pathogens and other detrimental factors of nature by the use of its secondary metabolites. Diverse pharmacological attributes viz. antibacterial, antifungal, cytotoxic, antioxidant etc. of the bryophytes has been reported mainly due to these secondary metabolites. Among the t ...
... A facile, economic and one-step synthesis strategy was applied for the synthesis of highly fluorescent water-soluble heteroatom doped carbon dots (CDs) from eight different amino acids viz., arginine, cysteine, glutamic acid, glutamine, aspartic acid, lysine, tyrosine, and methionine. Based on the higher quantum yield (38%) cysteine derived CDs were selected to explore their multi-functional behav ...
... Silver nanoparticles (AgNPs) were synthesized using amino acids (tyrosine and tryptophan) as reducing and capping agents, and they were incorporated into the agar to prepare antimicrobial composite films. The AgNPs solutions exhibited characteristic absorption peak at 420nm that showed a red shift to ∼434nm after forming composite with agar. XRD data demonstrated the crystalline structure of AgNPs ...
C. Tefiani; A. Riazi; F. Youcefi; S. Aazza; C. Gago; M.L. Faleiro; L.G. Pedro; J.G. Barroso; A.C. Figueiredo; C. Megías; I. Cortés-Giraldo; J. Vioque; M.G. Miguel
... The chemical composition, and antioxidant, antimicrobial and anti-proliferative activities of the essential oils of Ammoides pusilla (Apiaceae) and Thymus munbyanus (Lamiaceae), collected in Algeria, were studied. Cumin alcohol (44%), p -cymene (18%), limonene (14%), thymol (11%) and γ-terpinene (7%) predominated in A . pusilla essential oil, whereas carvacrol (71%) was dominant in T . munbyanus e ...
... Over the last few years, there has been an increasing interest in the use of natural substances for promoting human and animal health. Antibiotic resistance, enhanced by excessive use of antibiotics, has encouraged human and animal health authorities to consider and employ alternative approaches, including herbal and botanical medicine to combat invading microorganisms. Herein, the essential oils ...
... Herbal medications have been used for relief of symptoms of disease. Regardless of the great advances observed in current medicine in recent decades, plants still make a significant contribution to health care. An alarming increase in bacterial strains resistant to a number of antimicrobial agents demands that a renewed effort be made to seek antibacterial agents effective against pathogenic bacte ...
... In this study, the preparation method and characteristics of anatase titanium dioxide (TiO ₂) nanoparticle-loaded polylactide (PLA) films and their antibacterial efficacy against Klebsiella pneumoniae (ATCC 4352) and Staphylococcus aureus (ATCC 6538) bacterium were studied. A series of PLA nanocomposites containing, respectively, 0, 1, and 5% (wt.) titanium dioxide (TiO ₂) nanoparticles were prepa ...
Ma Ming; Rateb Mostafa E.; Teng Qihui; Yang Dong; Rudolf Jeffrey D.; Zhu Xiangcheng; Huang Yong; Zhao Li-Xing; Jiang Yi; Li Xiuling; Rader Christoph; Duan Yanwen; Shen Ben
... Angucyclines and angucyclinones are aromatic polyketides with a tetracyclic benz[a]anthracene skeleton. The benz[a]anthracene scaffold is biosynthesized by type II polyketide synthases that catalyze the decarboxylative condensation of a short acyl-CoA starter and nine extender units. Angucyclines and angucyclinones, the largest group of polycyclic aromatic polyketides, achieve structural diversity ...
Mycobacterium tuberculosis; alkaloids; antibacterial properties; multiple drug resistance; screening; tuberculosis
Abstract:
... AIMS: The interaction of quinolone and indoloquinazoline alkaloids concerning their antimycobacterial activity was studied. METHODS AND RESULTS: The antimycobacterial and modulating activity of evodiamine (1), rutaecarpine (2) and evocarpine (3) was tested on mycobacteria including three multidrug‐resistant (MDR) clinical isolates of Mycobacterium tuberculosis. Antagonistic effects were concluded ...
anti-infective agents; antibacterial properties; bacteria; biocompatibility; crosslinking; head and neck neoplasms; nanoparticles; patients; polyethyleneimine; quaternary ammonium compounds
Abstract:
... Polycationic nanoparticles show biocompatible, broad-spectrum bactericidal properties in vitro and in vivo when incorporated in denture lining material post-maxillectomy in head and neck cancer patients. In the present study, the synthesized Crosslinked quaternary ammonium polyethylenimine nanoparticles were found to have a strong bactericidal activity against a wide variety of microorganisms rapi ...
... Biomaterials used during surgery and wound treatment are of increasing importance in modern medical care. In the present study we set out to evaluate the addition of thrombin-derived host defense peptides to human acellular dermis (hAD, i.e. epiflex®). Antimicrobial activity of the functionalized hAD was demonstrated using radial diffusion and viable count assays against Gram-negative Escherichia ...
Euphorbia hirta; Pseudomonas aeruginosa; aerial parts; antibacterial properties; caffeic acid; epicatechin; fractionation; gastrointestinal system; high performance liquid chromatography; methanol; minimum inhibitory concentration; pathogens; spectroscopy; Malaysia
Abstract:
... Euphorbia hirta (L.) plant is traditionally used in Malaysia for the treatment of gastrointestinal, bronchial and respiratory ailments caused by nosocomial infectious agents. Bioactivity-guided fractionation of the methanol extract of the aerial parts of E. hirta and analysis using high-performance liquid chromatography have led to the isolation of two antibacterial compounds. These compounds were ...
... A silver–silica nano composite based geopolymer mortar has been developed by simple adsorption of silver in a suitable amount of a colloidal silica suspension for anti-bacterial property development. The silver nanoparticles (3–7 nm) were attached on the surface of 20–50 nm sized silica nanoparticles. The silver–silica nano-composite was characterized by Transmission Electron Microscopy (TEM), X-R ...
... Nanohydroxyapatite possesses exceptional biocompatibility and bioactivity regarding bone cells and tissues, justifying its use as a coating material or as a bone substitute. Unfortunately, this feature may also encourage bacterial adhesion and biofilm formation. Surface functionalization with antimicrobials is a promising strategy to reduce the likelihood of bacterial infestation and colonization ...