U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Publication year rev 7985-2015 Remove constraint Publication year rev: 7985-2015 Subject term caffeine Remove constraint Subject term: caffeine
Start Over

Search

270  Search Results

« Previous | 1 - 50 of 270 |
Number of results to display per page

Search Results

1. A Conceptual Demonstration of Decaffeination via Nanofiltration

Author:
Ong Yee Kang; Ng Hui Ting; Chung Tai-Shung
Source:
Industrial & Engineering Chemistry Research 2015 v.54 no.31 pp. 7737-7742
ISSN:
1520-5045
Subject:
caffeine; decaffeination; engineering; models; molecular weight; nanofiltration; temperature
Abstract:
... This study aims to evaluate the feasibility of using novel nanofiltration (NF) membranes for decaffeination of coffee wherein caffeine present in the feed solution is recovered at the permeate of the membrane. The NF hollow fiber membranes were fabricated and tested with model solutions to evaluate the recovery of caffeine as functions of molecular weight/size of organic molecules, caffeine concen ...
DOI:
10.1021/acs.iecr.5b01737

2. A Cup Today or a Pot Later: On the Discounting of Delayed Caffeinated Beverages

Author:
David P. Jarmolowicz; Shea M. Lemley; Dylan Cruse; Michael J. Sofis
Source:
Journal of agricultural & food industrial organization 2015 v.13 no.1 pp. 101-111
ISSN:
1542-0485
Subject:
beverages; caffeine; cocaine; drug abuse; obesity; questionnaires
Abstract:
... Delay discounting describes how the subjective value of a given commodity decreases as the delay to receiving that commodity increases. Decades of behavioral economic research have found that individuals suffering from a range of clinical conditions (e.g., drug addiction, obesity) tend to devalue delayed rewards more quickly than individuals without said clinical conditions and that such individua ...
DOI:
10.1515/jafio-2015-0021

3. A study on quality components and sleep-promoting effects of GABA black tea

Author:
Wenfang Zhao; Yun Li; William Ma; Yazhong Ge; Yahui Huang
Source:
Food & function 2015 v.6 no.10 pp. 3393-3398
ISSN:
2042-650X
Subject:
black tea; body weight; caffeine; drying; flavanols; free amino acids; gamma-aminobutyric acid; mice; pentobarbital; polyphenols; sleep; sodium
Abstract:
... The aims of this study were to analyze the changes in quality components of gamma (γ)-aminobutyric acid (GABA) black tea during processing, and to investigate the effect of three dosages of GABA black tea on sleep improvement. The results showed that the GABA content was increased significantly up to 2.70 mg g⁻¹ after vacuum anaerobic and aerobic treatment. In addition, the content of GABA after d ...
DOI:
10.1039/c5fo00265f

4. An optimized and validated SPE-LC–MS/MS method for the determination of caffeine and paraxanthine in hair

Author:
Pieter M.M. De Kesel; Willy E. Lambert; Christophe P. Stove
Source:
Talanta 2015 v.144 pp. 62-70
ISSN:
0039-9140
Subject:
buffers; caffeine; cleaning; decontamination; drugs; guidelines; isotope labeling; metabolites; pH; phenotype; proteinases; spectrometers
Abstract:
... Caffeine is the probe drug of choice to assess the phenotype of the drug metabolizing enzyme CYP1A2. Typically, molar concentration ratios of paraxanthine, caffeine’s major metabolite, to its precursor are determined in plasma following administration of a caffeine test dose. The aim of this study was to develop and validate an LC–MS/MS method for the determination of caffeine and paraxanthine in ...
DOI:
10.1016/j.talanta.2015.05.084

5. Application of gas chromatography-mass spectrometry and chemometrics methods for assessing volatile profiles of Pu-erh tea with different processing methods and ageing years

Author:
Shidong Lv; Yuanshuang Wu; Jifu Wei; Ming Lian; Chen Wang; Xuemei Gao; Qingxiong Meng
Source:
RSC advances 2015 v.5 no.107 pp. 87806-87817
ISSN:
2046-2069
Subject:
beta-ionone; caffeine; cedrol; chemometrics; cluster analysis; gas chromatography-mass spectrometry; headspace analysis; linalool; manufacturing; multivariate analysis; odors; palmitic acid; principal component analysis; solid phase microextraction; tea; volatile compounds
Abstract:
... Volatile changes and the post-fermentation ageing process of tea remain largely unknown. Additionally, the understanding of ageing and storage processes of tea mostly rely on sensory experience and lack the support of scientific and accurate data. In this paper, a method was developed based on head-space solid phase microextraction/gas chromatography-mass spectrometry (HS-SPME/GC-MS) combined with ...
DOI:
10.1039/c5ra15381f

6. Are standard tests sensitive enough to evaluate effects of human pharmaceuticals in aquatic biota? Facing changes in research approaches when performing risk assessment of drugs

Author:
G.V. Aguirre-Martínez; M.A. Owuor; C. Garrido-Pérez; M.J. Salamanca; T.A. Del Valls; M.L. Martín-Díaz
Source:
Chemosphere 2015 v.120 pp. 75-85
ISSN:
0045-6535
Subject:
Isochrysis galbana; Paracentrotus lividus; Selenastrum capricornutum; Vibrio fischeri; acute toxicity; adverse effects; aquatic environment; bacteria; bioassays; bioluminescence; caffeine; dimethyl sulfoxide; environmental exposure; environmental impact; freshwater; guidelines; humans; ibuprofen; microalgae; novobiocin; risk; risk characterization; teratogenicity
Abstract:
... Nowadays, the presence of pharmaceutical products in aquatic environments is not only common, but is also of significant concern regarding the adverse effect they may produce to aquatic biota. In order to determine the adverse effects of caffeine (CAF), ibuprofen (IBU), carbamazepine (CBZ) and novobiocin (NOV), at environmental occurring concentrations, standardized endpoints applied in current gu ...
DOI:
10.1016/j.chemosphere.2014.05.087

7. Assessment of caffeine intake in the Korean population

Author:
Ho Soo Lim; Ju Young Hwang; Jae Chon Choi; Meehye Kim
Source:
Food additives & contaminants 2015 v.32 no.11 pp. 1786-1798
ISSN:
1944-0057
Subject:
National Health and Nutrition Examination Survey; adults; caffeine; carbonated beverages; high performance liquid chromatography; markets; Korean Peninsula
Abstract:
... An improved method for the analysis of caffeine in foods by HPLC was validated by measuring several analytical parameters. The caffeine contents of 1202 products available from Korean markets were analysed. A consumption study was conducted by using data from the Korea National Health and Nutrition Examination Survey (KNHANES), 2010–12, to estimate the caffeine intakes of the Korean population. Th ...
DOI:
10.1080/19440049.2015.1077396

8. Associations of chemical tracers and faecal indicator bacteria in a tropical urban catchment

Author:
E. Ekklesia; P. Shanahan; L.H.C. Chua; H.S. Eikaas
Source:
Water research 2015 v.75 pp. 270-281
ISSN:
0043-1354
Subject:
acetaminophen; active ingredients; boron; caffeine; cholesterol; coprostanol; data collection; detergents; drainage water; feces; human health; humans; ibuprofen; indicator species; land use; methylene blue; phthalates; residential areas; saccharin; sewage; sucralose; surface water; tracer techniques; wastewater; water pollution; water quality; watersheds
Abstract:
... Surface water contamination by human faecal wastes is a widespread hazard for human health. Faecal indicator bacteria (FIB) are the most widely used indicators to assess surface water quality but are less-human-specific and have the potential to survive longer and/or occur naturally in tropical areas. In this study, 13 wastewater chemicals (chloride, boron, orthosphophate, detergents as methylene ...
DOI:
10.1016/j.watres.2015.02.037

9. Attenuation of trace organic compounds (TOrCs) in bioelectrochemical systems

Author:
Craig M. Werner; Christiane Hoppe-Jones; Pascal E. Saikaly; Bruce E. Logan; Gary L. Amy
Source:
Water research 2015 v.73 pp. 56-67
ISSN:
0043-1354
Subject:
acetates; atrazine; biocides; bioelectrochemistry; biotransformation; caffeine; carbon; deet; electric current; electrodes; electrolysis; energy; hydrogen; hydrophilicity; microbial fuel cells; microorganisms; municipal wastewater; pH; phosphates; sorption; trimethoprim; wastewater treatment
Abstract:
... Microbial fuel cells (MFCs) and microbial electrolysis cells (MECs) are two types of microbial bioelectrochemical systems (BESs) that use microorganisms to convert chemical energy in wastewaters into useful energy products such as (bio)electricity (MFC) or hydrogen gas (MEC). These two systems were evaluated for their capacity to attenuate trace organic compounds (TOrCs), commonly found in municip ...
DOI:
10.1016/j.watres.2015.01.013

10. Bioprocess of robusta cherry coffee with polyphenol oxidase and quality enhancement

Author:
Ritika Mathur; P. N. Navya; K. Basavaraj; Pushpa S. Murthy
Source:
European food research & technology 2015 v.240 no.2 pp. 319-325
ISSN:
1438-2377
Subject:
Coffea arabica; Coffea canephora; Pleurotus florida; Pleurotus ostreatus; ammonium sulfate; beans; bioprocessing; bitterness; caffeine; catechol oxidase; chemical reactions; coffee beans; consumer satisfaction; food research; foods; fruiting bodies; molecular weight; pH; phenolic compounds; polyacrylamide gel electrophoresis; proteins; temperature
Abstract:
... Flavor plays an important role in consumer satisfaction and influences further consumption of foods. Robusta coffee is rich in caffeine and phenolics and is undesirable for coffee connoisseurs compared to arabica coffee. The exogenous polyphenol oxidase (4,000 U/ml) was extracted from the fruiting bodies of Pleurotus florida otherwise referred as the oyster mushroom. The polyphenol oxidase (PPO) w ...
DOI:
10.1007/s00217-014-2331-8

11. Blockade of phosphodiesterase 4 reverses morphine-induced ventilatory disturbance without loss of analgesia

Author:
Satoko Kimura; Yoshiaki Ohi; Akira Haji
Source:
Life sciences 2015 v.127 pp. 32-38
ISSN:
0024-3205
Subject:
adenosine; adverse effects; analgesia; caffeine; cyclic AMP; enzyme inhibitors; morphine; narcotics; nerve tissue; neurons; rats
Abstract:
... Ventilatory disturbance is a fatal side-effect of opioid analgesics. Separation of analgesia from ventilatory depression is important for therapeutic use of opioids. It has been suggested that opioid-induced ventilatory depression results from a decrease in adenosine 3′,5′-cyclic monophosphate content in the respiratory-related neurons. Therefore, we examined the effects of caffeine, a methylxanth ...
DOI:
10.1016/j.lfs.2015.02.006

12. Caffeine ameliorates high energy diet-induced hepatic steatosis: sirtuin 3 acts as a bridge in the lipid metabolism pathway

Author:
Shi-Jie Zhang; Yi-Fang Li; Guo-En Wang; Rui-Rong Tan; Bun Tsoi; Gao-Wei Mao; Yu-Jia Zhai; Ling-Fang Cao; Min Chen; Hiroshi Kurihara; Qi Wang; Rong-Rong He
Source:
Food & function 2015 v.6 no.8 pp. 2578-2587
ISSN:
2042-650X
Subject:
adenosine diphosphate; adenosine triphosphate; alanine transaminase; aspartate transaminase; body weight; caffeine; cyclic AMP; energy; fatty liver; high energy diet; human cell lines; lipid metabolism; lipids; liver; mice; phosphorylation; small interfering RNA; staining
Abstract:
... The beneficial effect of caffeine-containing food on non-alcoholic fatty liver disease (NAFLD) has been widely reported. The aim of this study was to explore the effect of caffeine on hepatic steatosis. C57BL/6 mice were randomly assigned to a normal diet or a high energy diet (HED). Caffeine was given to HED mice by oral gavage. Body weights, lipids in the liver and liver damage were measured. Me ...
DOI:
10.1039/c5fo00247h

13. Caffeine dimerization: effects of sugar, salts, and water structure

Author:
Seishi Shimizu
Source:
Food & function 2015 v.6 no.10 pp. 3228-3235
ISSN:
2042-650X
Subject:
additives; bitterness; caffeine; dimerization; models; salts; sugars; thermodynamics
Abstract:
... Sugars and salts strongly affect the dimerization of caffeine in water. Such a change of dimerization, considered to be crucial for bitter taste suppression, has long been rationalized by the change of “water structure” induced by the additives; “kosmotropic” (water structure enhancing) salts and sugars promote dimerization, whereas “chaotropic” (water structure breaking) salts suppress dimerizati ...
DOI:
10.1039/c5fo00610d

14. Caffeine increases sugar-sweetened beverage consumption in a free-living population: a randomised controlled trial

Author:
Russell S. J. Keast; Boyd A. Swinburn; Dhoungsiri Sayompark; Susie Whitelock; Lynn J. Riddell
Source:
British journal of nutrition 2015 v.113 no.2 pp. 366-371
ISSN:
1475-2662
Subject:
ad libitum feeding; caffeine; flavor; food additives; food records; hedonic scales; high energy foods; obesity; randomized clinical trials; sugar sweetened beverages
Abstract:
... Excessive sugar-sweetened beverage (SSB) consumption has been associated with overweight and obesity. Caffeine is a common additive to SSB, and through dependence effects, it has the potential to promote the consumption of caffeine-containing foods. The objective of the present study was to assess the influence that caffeine has on the consumption of SSB. Participants (n 99) were blindly assigned ...
DOI:
10.1017/S000711451400378X
PubMed:
25567475

15. Caffeine ingestion does not affect afternoon muscle power and fatigue during the Wingate test in elite judo players

Author:
Makram Souissi; Asma Aloui; Hamdi Chtourou; Hassen Ben Aouicha; Rim Atheymen; Zouhair Sahnoun
Source:
Biological rhythm research 2015 v.46 no.2 pp. 291-298
ISSN:
1744-4179
Subject:
anxiety; biological rhythms; caffeine; ingestion; muscles; placebos; vigor
Abstract:
... The purpose of the present study was to evaluate the effect of caffeine ingestion on elite judo players’ mood states, simple reaction time, and muscle power during the Wingate test in the afternoon. Ten elite judo players (age: 21.08 ± 1.16 years, body mass: 83.75 ± 20.2 kg, height: 1.76 ± 0.07 m) took part in this study. The performance variables were measured during two test sessions scheduled a ...
DOI:
10.1080/09291016.2014.994857

16. Caffeine inhibits hepatitis C virus replication in vitro

Author:
Mariana N. Batista; Bruno M. Carneiro; Ana Cláudia S. Braga; Paula Rahal
Source:
Archives of virology 2015 v.160 no.2 pp. 399-407
ISSN:
0304-8608
Subject:
Hepatitis C virus; biochemistry; caffeine; dose response; fibrosis; genotype; hepatitis C; hepatoma; liver; liver function; virus replication
Abstract:
... Hepatitis C is considered the major cause of cirrhosis and hepatocellular carcinoma. Conventional treatment is not effective against some hepatitis C virus (HCV) genotypes; therefore, new treatments are needed. Coffee and, more recently, caffeine, have been found to have a beneficial effect in several disorders of the liver, including those manifesting abnormal liver biochemistry, cirrhosis and he ...
DOI:
10.1007/s00705-014-2302-1

17. Caffeine stimulates in vitro pituitary LH secretion in lipopolysaccharide-treated ewes

Author:
Andrzej Przemysław Herman; Anna Herman; Janina Skipor; Agata Krawczyńska; Joanna Bochenek; Dorota Tomaszewska-Zaremba
Source:
Reproductive Biology 2015 v.15 no.1 pp. 20-26
ISSN:
1642-431X
Subject:
anterior pituitary; caffeine; endotoxins; ewes; explants; gene expression; gonadotropin-releasing hormone; in vitro studies; lipopolysaccharides; luteinizing hormone; receptors; secretion
Abstract:
... The study was designed to determine the effects of caffeine on luteinizing hormone (LH) secretion and gene expression of caffeine-associated receptors in anterior pituitary (AP) explants obtained from saline- and lipopolysaccharide (LPS)-treated ewes. Animals had been treated with LPS or saline daily for seven days. Three hours after the last injection of LPS/saline, the AP were collected and divi ...
DOI:
10.1016/j.repbio.2014.12.001

18. Caffeine’s Antioxidant Potency Optically Sensed with Double-Stranded DNA-Encased Single-Walled Carbon Nanotubes

Author:
Zhao Edward H.; Ergul Busra; Zhao Wei
Source:
Journal of physical chemistry 2015 v.119 no.10 pp. 4068-4075
ISSN:
1520-5207
Subject:
DNA; ascorbic acid; caffeine; carbon nanotubes; hydrogen peroxide; hydroxyl radicals; oxidative stress; physical chemistry; uric acid
Abstract:
... There is great interest in developing a sensitive method being able to quantitatively measure and compare antioxidant potencies of samples of interest against multiple reactive oxygen species (ROS) whose imbalance could cause oxidative stress. Here, a sensitive nanoprobe, double-stranded DNA encased single-walled carbon nanotubes (SWNTs) has been developed to determine antioxidant potencies of sel ...
DOI:
10.1021/acs.jpcb.5b00708

19. Can Energy Drinks Increase the Desire for More Alcohol?

Author:
Cecile A Marczinski
Source:
Advances in food and nutrition research 2015 v.6 no.1 pp. 96-101
ISSN:
1043-4526
Subject:
alcohol abuse; alcohol drinking; alcohols; binging; caffeine; energy drinks; epidemiological studies; humans; markets; mixers; public health; risk
Abstract:
... Energy drinks, the fastest growing segment in the beverage market, have become popular mixers with alcohol. The emerging research examining the use of alcohol mixed with energy drinks (AmEDs) indicates that the combination of caffeine-containing energy drinks with alcohol may be riskier than the use of alcohol alone. The public health concerns arising from AmED use are documented in different rese ...
DOI:
10.3945/an.114.007393
PubMed:
25593148
PubMed Central:
PMC4288285

20. Characterizing Drug Release from Nonfouling Polyampholyte Hydrogels

Author:
Barcellona Marcos N.; Johnson Nicholas; Bernards Matthew T.
Source:
Langmuir 2015 v.31 no.49 pp. 13402-13409
ISSN:
1520-5827
Subject:
bioactive compounds; caffeine; chlorides; drugs; enzyme-linked immunosorbent assay; hydrogels; ionic strength; methylene blue; pH; tissue repair
Abstract:
... Controlled delivery of bioactive signaling molecules and drugs is essential for the development of the next generation of tissue regeneration scaffolds. However, these molecules must be delivered from a nonfouling platform, so that the therapeutic role is not masked by the naturally occurring foreign body response. Therefore, the purpose of this study is to characterize the release profiles of thr ...
DOI:
10.1021/acs.langmuir.5b03597

21. Coffee Silverskin: Characterization, Possible Uses, and Safety Aspects

Author:
Tullia Gallina Toschi; Vladimiro Cardenia; Giorgio Bonaga; Mara Mandrioli; Maria Teresa Rodriguez-Estrada
Source:
Journal of agricultural and food chemistry 2014 v.62 no.44 pp. 10836-10844
ISSN:
0021-8561
Subject:
caffeine; cellulose; coffee products; dietary fiber; humans; industry; linoleic acid; livestock; ochratoxin A; oxidation; phytosterols; polyphenols; risk
Abstract:
... The reuse of coffee silverskin (CS), the main waste product of the coffee-roasting industry, could be an alternative to its environmental disposal. However, CS could also contain undesirable compounds, such as ochratoxin A (OTA) and phytosterol oxidation products (POPs). A study on the composition of CS (caffeine, moisture, dietary fibers, carbohydrates, and polyphenol contents) was carried out, w ...
DOI:
10.1021/jf503200z

22. Coffee enriched with willow (Salix purpurea and Salix myrsinifolia) bark preparation – Interactions of antioxidative phytochemicals in a model system

Author:
Agata Durak; Urszula Gawlik-Dziki; Danuta Sugier
Source:
Journal of functional foods 2015 v.18 pp. 1106-1116
ISSN:
1756-4646
Subject:
Salix purpurea; active ingredients; antioxidant activity; bark; caffeine; chlorogenic acid; coffee (beverage); hydroxyl radicals; lipids; oxidation; phytopharmaceuticals; raw materials; synergism
Abstract:
... Coffee and willow are known to be valuable sources of biologically active phytochemicals such as chlorogenic acid, caffeine and salicin. The aim of this study was to determine the interactions between the active compounds from coffee and willow bark (Salix purpurea and Salix myrsinifolia). Raw materials and their mixtures were characterized by multidirectional antioxidant activities; however, bioa ...
DOI:
10.1016/j.jff.2014.06.012

23. Comparison of trapping profiles between d-peptides and glutathione in the identification of reactive metabolites

Author:
Jaana E. Laine; Merja R. Häkkinen; Seppo Auriola; Risto O. Juvonen; Markku Pasanen
Source:
Toxicology reports 2015 v.2 pp. 1024-1032
ISSN:
2214-7500
Subject:
Lewis acids; amino acid sequences; biocatalysts; caffeine; glutathione; gold; humans; ibuprofen; liver microsomes; metabolites; mice; toxicity; toxicology
Abstract:
... Qualitative trapping profile of reactive metabolites arising from six structurally different compounds was tested with three different d-peptide isomers (Peptide 1, gly–tyr–pro–cys–pro–his-pro; Peptide 2, gly–tyr–pro–ala–pro–his–pro; Peptide 3, gly–tyr–arg–pro–cys–pro–his–lys–pro) and glutathione (GSH) using mouse and human liver microsomes as the biocatalyst. The test compounds were classified ei ...
DOI:
10.1016/j.toxrep.2015.07.002

24. Conductive diamond electrochemical oxidation of caffeine-intensified biologically treated urban wastewater

Author:
María J. Martín de Vidales; María Millán; Cristina Sáez; José F. Pérez; Manuel A. Rodrigo; Pablo Cañizares
Source:
Chemosphere 2015 v.136 pp. 281-288
ISSN:
0045-6535
Subject:
ammonium compounds; caffeine; electrochemistry; hydrogen peroxide; nitrates; oxidants; oxidation; perchlorates; sulfates; wastewater
Abstract:
... In this work, the usefulness of Conductive Diamond Electrochemical Oxidation (CDEO) to degrade caffeine in real urban wastewater matrixes was assessed. The oxidation of actual wastewater intensified with caffeine (from 1 to 100mgL−1) was studied, paying particular attention to the influence of the initial load of caffeine and the differences observed during the treatment of caffeine in synthetic w ...
DOI:
10.1016/j.chemosphere.2015.05.077

25. Corrigendum to “Sorption/desorption of non-hydrophobic and ionisable pharmaceutical and personal care products from reclaimed water onto/from a natural sediment” Sci Total Environ 472 (2014) 273–281

Author:
Virtudes Martínez-Hernández; Raffaella Meffe; Sonia Herrera; Elena Arranz; Irene de Bustamante
Source:
Science of the total environment 2015 v.505 pp. 1232-1233
ISSN:
0048-9697
Subject:
acetaminophen; caffeine; carbon; desorption; inorganic ions; ionization; organic matter; personal care products; rain; sandy loam soils; sediments; sulfamethoxazole
Abstract:
... In the present work, the sorption of pharmaceutical and personal care products (PPCPs) (acetaminophen, atenolol, carbamazepine, caffeine, naproxen and sulphamethoxazole) onto the natural organic matter (NOM) and the inorganic surfaces of a natural sandy loam sediment was quantified separately. The quantification was based on the PPCP charge, their degree of ionisation, their octanol-water partitio ...
DOI:
10.1016/j.scitotenv.2014.10.104

26. Determination of phytochemicals, antioxidant activity and total phenolic content in Andrographis paniculata using chromatographic methods

Author:
Marzanna Kurzawa; Anna Filipiak-Szok; Ewa Kłodzińska; Edward Szłyk
Source:
Journal of Chromatography B 2015 v.995-996 pp. 101-106
ISSN:
1570-0232
Subject:
2,2-diphenyl-1-picrylhydrazyl; Andrographis paniculata; analysis of variance; antioxidant activity; caffeine; cluster analysis; dietary supplements; gas chromatography-mass spectrometry; high performance liquid chromatography; leaves; phytopharmaceuticals; principal component analysis; strychnine; theobromine; theophylline; yohimbine
Abstract:
... Antioxidant activity, total phenolics content and selected phytochemicals (alkaloids and andrographolides) were determined in Andrographis paniculata and in dietary supplements containing this plant. Antioxidant activity was measured by FRAP, CUPRAC and DPPH procedures and ranged from 503.36 to 6164.09μmol TE/100g d.m. depending on methods, part of plant and kind of dietary supplement. The total p ...
DOI:
10.1016/j.jchromb.2015.05.021

27. Development and validation of a rapid derivative spectrophotometric method for simultaneous determination of acetaminophen, ibuprofen and caffeine

Author:
Effat Souri; Seyed Adel Mousavi Nasab; Massoud Amanlou; Maliheh Barazandeh Tehrani
Source:
Journal of analytical chemistry 2015 v.70 no.3 pp. 333-338
ISSN:
1061-9348
Subject:
acetaminophen; caffeine; drug formulations; ibuprofen; quality control; spectrophotometers; wavelengths
Abstract:
... A zero-crossing derivative spectrophotometric method was used for the simultaneous determination of acetaminophen, ibuprofen and caffeine. The derivative spectra of standard solutions of each compound were obtained at different orders to find out the suitable zero-crossing points. Under the optimized conditions, determination of acetaminophen was performed at wavelengths of 311 and 270 nm using th ...
DOI:
10.1134/S1061934815030041

28. Differential regulation of caffeine metabolism in Coffea arabica (Arabica) and Coffea canephora (Robusta)

Author:
Charlène Perrois; Susan R. Strickler; Guillaume Mathieu; Maud Lepelley; Lucie Bedon; Stéphane Michaux; Jwanro Husson; Lukas Mueller; Isabelle Privat
Source:
Planta 2015 v.241 no.1 pp. 179-191
ISSN:
0032-0935
Subject:
Coffea canephora; amino acids; beans; beverages; caffeine; coffee beans; doubled haploids; gene expression; genes; haploidy; leaves; metabolism; metabolites; phylogeny; purine nucleotides; transcription (genetics)
Abstract:
... Caffeine is a metabolite of great economic importance, especially in coffee, where it influences the sensorial and physiological impacts of the beverage. Caffeine metabolism in the Coffea species begins with the degradation of purine nucleotides through three specific N-methyltransferases: XMT, MXMT and DXMT. A comparative analysis was performed to clarify the molecular reasons behind differences ...
DOI:
10.1007/s00425-014-2170-7
PubMed:
25249475
PubMed Central:
PMC4282694

29. Differentiation of degrees of ripeness of Catuai and Tipica green coffee by chromatographical and statistical techniques

Author:
Samo Smrke; Ivana Kroslakova; Alexia N. Gloess; Chahan Yeretzian
Source:
Food chemistry 2015 v.174 pp. 637-642
ISSN:
0308-8146
Subject:
caffeine; chlorogenic acid; farms; gas chromatography; gel chromatography; headspace analysis; high performance liquid chromatography; hydrophilic interaction chromatography; mass spectrometry; principal component analysis; sucrose; volatile compounds
Abstract:
... The quality of green coffee is influenced by the degree of ripeness of the fruit at harvest. The aim of this study was to identify chemical markers differentiating between degrees of ripeness. Two coffee varieties, Catuai and Tipica, from the same farm were analysed using the following parameters and methods: caffeine and chlorogenic acid content using high-performance liquid chromatography (HPLC) ...
DOI:
10.1016/j.foodchem.2014.11.060

30. Differing chemical compositions of three teas may explain their different effects on acute blood pressure in spontaneously hypertensive rats

Author:
Shan‐Bing Li; Yi‐Fang Li; Zhong‐Fu Mao; Hui‐Hua Hu; Shu‐Hua Ouyang; Yan‐Ping Wu; Bun Tsoi; Pin Gong; Hiroshi Kurihara; Rong‐Rong He
Source:
Journal of the science of food and agriculture 2015 v.95 no.6 pp. 1236-1242
ISSN:
0022-5142
Subject:
acute effects; caffeine; diastolic blood pressure; epinephrine; heart rate; intragastric administration; leaves; norepinephrine; people; rats; systolic blood pressure; tea; theobromine
Abstract:
... BACKGROUND: Heavy tea consumption is suggested to be unsuitable for hypertensive people. However, the bioactive substances in different varieties of tea leaves are very different. This study compares the effects of three Chinese teas – C. sinensis, C. ptilophylla and C. assamica var. kucha – on blood pressure (BP) and heart rate in spontaneously hypertensive rats (SHRs). RESULTS: Intragastric admi ...
DOI:
10.1002/jsfa.6811

31. Direct injection of tissue extracts in liquid chromatography/tandem mass spectrometry for the determination of pharmaceuticals and other contaminants of emerging concern in mollusks

Author:
Stéphane Bayen; Elvagris Segovia Estrada; Guillaume Juhel; Barry C. Kelly
Source:
Analytical and bioanalytical chemistry 2015 v.407 no.19 pp. 5553-5558
ISSN:
1618-2642
Subject:
Perna viridis; Polymesoda; atrazine; caffeine; clams; coastal water; detection limit; drugs; endocrine-disrupting chemicals; isotope labeling; liquid chromatography; monitoring; mussels; solvents; tandem mass spectrometry; Singapore
Abstract:
... In the present study, a straightforward approach was validated for the analysis of pharmaceutically active compounds and endocrine-disrupting chemicals in the mollusk tissues, with a focus on two species commonly consumed in Southeast Asia (green mussels: Perna viridis; lokan clams: Polymesoda expansa). This approach relied on a simple solvent extraction (shaker table) followed by direct injection ...
DOI:
10.1007/s00216-015-8760-9

32. Distribution, mass load and environmental impact of multiple-class pharmaceuticals in conventional and upgraded municipal wastewater treatment plants in East China

Author:
Xiangjuan Yuan; Zhimin Qiang; Weiwei Ben; Bing Zhu; Jiuhui Qu
Source:
Environmental science 2015 v.17 no.3 pp. 596-605
ISSN:
2050-7895
Subject:
adsorption; algae; antibiotic residues; anticonvulsants; aquatic environment; azithromycin; beta-adrenergic antagonists; biodegradation; biofilm; biological treatment; caffeine; ciprofloxacin; clarithromycin; dihydrofolate reductase; environmental impact; enzyme inhibitors; lipids; municipal wastewater; norfloxacin; ofloxacin; oxidation; risk; sludge; sulfamethoxazole; tetracyclines; wastewater treatment; China
Abstract:
... The occurrence, fate and environmental impact of 30 pharmaceuticals including sulfonamides, fluoroquinolones, tetracyclines, macrolides, dihydrofolate reductase inhibitors, β-blockers, antiepileptics, lipid regulators, and stimulants were studied in two municipal wastewater treatment plants (WWTPs) located in Wuxi City, East China. A total of 23 pharmaceuticals were detected in wastewater samples, ...
DOI:
10.1039/c4em00596a

33. Dose-dependent effects of caffeine in human Sertoli cells metabolism and oxidative profile: Relevance for male fertility

Author:
Tânia R. Dias; Marco G. Alves; Raquel L. Bernardino; Ana D. Martins; Ana C. Moreira; Joaquina Silva; Alberto Barros; Mário Sousa; Branca M. Silva; Pedro F. Oliveira
Source:
Toxicology 2015 v.328 pp. 12-20
ISSN:
0300-483X
Subject:
Sertoli cells; aerobiosis; antioxidant activity; beverages; caffeine; dose response; germ cells; glucose transporters; humans; lactic acid; male fertility; males; spermatogenesis
Abstract:
... Caffeine is a widely consumed substance present in several beverages. There is an increasing consumption of energetic drinks, rich in caffeine, among young individuals in reproductive age. Caffeine has been described as a modulator of cellular metabolism. Hence, we hypothesized that it alters human Sertoli cells (hSCs) metabolism and oxidative profile, which are essential for spermatogenesis. For ...
DOI:
10.1016/j.tox.2014.12.003

34. Draft Genome Sequence of the Bacterium Pseudomonas putida CBB5, Which Can Utilize Caffeine as a Sole Carbon and Nitrogen Source

Author:
Erik M. Quandt; Ryan M. Summers; Mani V. Subramanian; Jeffrey E. Barrick
Source:
Genome Announcements 2015 v.3 no.3 pp. e00640-15
ISSN:
2169-8287
Subject:
Pseudomonas putida; bacteria; caffeine; carbon; enzymes; multigene family; nitrogen; nucleotide sequences; soil
Abstract:
... Pseudomonas putida CBB5 was isolated from soil by enriching for growth on caffeine (1,3,7-trimethylxanthine). The draft genome of this strain is 6.9 Mb, with 5,941 predicted coding sequences. It includes the previously studied Alx gene cluster encoding alkylxanthine N -demethylase enzymes and other genes that enable the degradation of purine alkaloids. ...
DOI:
10.1128/genomeA.00640-15
PubMed:
26067973
PubMed Central:
PMC4463537

35. Drug cross-contamination of latent fingermarks during routine powder dusting detected by SALDI TOF MS

Author:
Latha Sundar; Frederick Rowell
Source:
Analytical methods 2015 v.7 no.9 pp. 3757-3763
ISSN:
1759-9679
Subject:
acetaminophen; aspirin; brushes; caffeine; cocaine; cross contamination; desorption; dusting; illicit drugs; ionization; magnetism; mass spectrometry; methadone; powders; squirrels; therapeutics
Abstract:
... The process of dusting powders over latent fingermarks was shown to transfer drug contact residues between adjacent marks. This was seen for marks contaminated after contact with two drugs of abuse (cocaine and methadone) and three therapeutic drugs (caffeine, aspirin and paracetamol). The powders used were a commercial black powder, and α-cyano-4-hydroxycinnamic acid both of which also act as ion ...
DOI:
10.1039/c5ay00598a

36. Eating behavior by sleep duration in the Hispanic Community Health Study/Study of Latinos

Author:
Yasmin Mossavar-Rahmani; Molly Jung; Sanjay R. Patel; Daniela Sotres-Alvarez; Raanan Arens; Alberto Ramos; Susan Redline; Cheryl L. Rock; Linda Van Horn
Source:
Appetite 2015 v.95 pp. 275-284
ISSN:
0195-6663
Subject:
Hispanics; Latinos; body mass index; caffeine; calcium; cities; cohort studies; community health; diabetes; diet recall; eating habits; education; employment; healthy diet; income; linear models; nutrient intake; nutrients; nutritional adequacy; obesity; potassium; regression analysis; risk factors; saturated fats; sleep; stroke; United States
Abstract:
... Sleep is an important pillar of health and a modifiable risk factor for diabetes, stroke and obesity. Little is known of diet and sleep patterns of Hispanics/Latinos in the US. Here we examine eating behavior as a function of sleep duration in a sub-sample of 11,888 participants from the Hispanic Community Health Study/Study of Latinos, a community-based cohort study of Hispanics aged 18–74 years ...
DOI:
10.1016/j.appet.2015.07.014
PubMed:
26189885
PubMed Central:
PMC4589504

37. Effect of extraction time on antioxidants and bioactive volatile components of green tea (Camellia sinensis), using GC/MS

Author:
Mudasir Ahmad; Waqas N. Baba; Adil Gani; Touseef Ahmed Wani; Asir Gani; F.A. Masoodi; Fatih Yildiz
Source:
Cogent food & agriculture 2015 v.1 no.1 pp. 1106387
ISSN:
2331-1932
Subject:
Camellia sinensis; acetic acid; agriculture; caffeine; green tea; leaves; linoleic acid; myristic acid; oleic acid; palmitic acid; polyphenols; stearic acid; temperature
Abstract:
... Two green tea types, leaf grade and sanding, were extracted at different time intervals: 20, 40, and 120 min at a constant temperature of 50°C. The extracts were analyzed by GC/MS technique. The major compounds identified were myristic acid, palmitic acid, stearic acid, oleic acid, 1H-purine-2,6-dione, caffeine, linoleic acid, diethyl ester, and 1H-purine-6-amine. Stearic acid, palmitic acid, lino ...
DOI:
10.1080/23311932.2015.1106387

38. Effect of post-exercise caffeine and green coffee bean extract consumption on blood glucose and insulin concentrations

Author:
Jason R. Beam; Ann L. Gibson; Chad M. Kerksick; Carole A. Conn; Ailish C. White; Christine M. Mermier
Source:
Nutrition 2015 v.31 no.2 pp. 292-297
ISSN:
0899-9007
Subject:
bicycling; blood glucose; blood sampling; body mass index; body weight; caffeine; chlorogenic acid; coffee beans; diet therapy; exercise; glucose; glucose tolerance; humans; insulin; males; placebos
Abstract:
... The aim of this study was to investigate the effects of ingesting caffeine and green coffee bean extract on blood glucose and insulin concentrations during a post-exercise oral glucose tolerance test.Ten male cyclists (age: 26 ± 5 y; height: 179.9 ± 5.4 cm; weight: 77.6 ± 13.3 kg; body mass index: 24 ± 4.3 kg/m²; VO2 peak: 55.9 ± 8.4 mL·kg·min⁻¹) participated in this study. In a randomized order, ...
DOI:
10.1016/j.nut.2014.07.012

39. Effects of different brewing conditions on catechin content and sensory acceptance in Turkish green tea infusions

Author:
Sena Saklar; Erdal Ertas; Ibrahim S. Ozdemir; Bulent Karadeniz
Source:
Journal of food science and technology 2015 v.52 no.10 pp. 6639-6646
ISSN:
0022-1155
Subject:
brewing; caffeine; catechin; color; green tea; odors; sensory evaluation; taste; tea (beverage); temperature; Turkey (country)
Abstract:
... The optimal brewing conditions for Turkish green tea were determined on the basis of extracted catechins and sensory attributes. Green tea infusions were prepared at 75, 85 and 95 °C with brewing times of 1, 2, 3, 5, 10, 20, 30 and 45 min. The amounts of epistructured catechins (EGCG, EGC, ECG, EC), non-epistructured catechins (C, GC, GCG) and caffeine in brewed tea samples were analysed. Sensory ...
DOI:
10.1007/s13197-015-1746-y
PubMed:
26396411
PubMed Central:
PMC4573099

40. Ergogenic effects of caffeine and sodium bicarbonate supplementation on intermittent exercise performance preceded by intense arm cranking exercise

Author:
Matthaus Marriott; Peter Krustrup; Magni Mohr
Source:
Journal of the International Society of Sports Nutrition 2015 v.12 no.1 pp. 13
ISSN:
1550-2783
Subject:
acidification; athletes; blood; blood glucose; caffeine; exercise; glucose; heart rate; lactic acid; males; placebos; protocols; sodium bicarbonate; sports nutrition
Abstract:
... BACKGROUND: Caffeine and sodium bicarbonate ingestion have been suggested to improve high-intensity intermittent exercise, but it is unclear if these ergogenic substances affect performance under provoked metabolic acidification. To study the effects of caffeine and sodium bicarbonate on intense intermittent exercise performance and metabolic markers under exercise-induced acidification, intense a ...
DOI:
10.1186/s12970-015-0075-x
PubMed:
25750597
PubMed Central:
PMC4351945

41. Espresso coffee residues as a nitrogen amendment for small‐scale vegetable production

Author:
Soraia Cruz; Cláudia SC Marques dos Santos Cordovil
Source:
Journal of the science of food and agriculture 2015 v.95 no.15 pp. 3059-3066
ISSN:
0022-5142
Subject:
Daucus carota; Lactuca sativa; Spinacia oleracea; caffeine; carrots; field experimentation; germination; lettuce; mineralization; nitrogen; phosphorus; plant nutrition; spinach; vegetable growing
Abstract:
... BACKGROUND: Espresso coffee grounds constitute a residue which is produced daily in considerable amounts, and is often pointed out as being potentially interesting for plant nutrition. Two experiments (incubations and field experiments) were carried out to evaluate the potential nitrogen (N) and phosphorus (P) supply for carrot (Daucus carota L.), spinach (Spinacea oleracea L.) and lettuce (Lactuc ...
DOI:
10.1002/jsfa.7325

42. Feeling smart: Effects of caffeine and glucose on cognition, mood and self-judgment

Author:
Susann Ullrich; Yfke C. de Vries; Simone Kühn; Dimitris Repantis; Martin Dresler; Kathrin Ohla
Source:
Physiology & behavior 2015 v.151 pp. 629-637
ISSN:
0031-9384
Subject:
caffeine; cognition; education; emotions; energy; energy drinks; glucose; memory; motivation; placebos; young adults
Abstract:
... During education and early career, young adults often face examinations and assessment centers. Coffee and energy drinks are convenient and commonly used to enhance or maintain performance in these situations. Whether these macronutrients improve performance in a demanding and drawn-out multi-task situation is not clear. Using double-blind, placebo-controlled studies, we set out to examine the eff ...
DOI:
10.1016/j.physbeh.2015.08.028

43. Free radical polymerization of caffeine‐containing methacrylate monomers

Author:
Ashley M. Nelson; Sean T. Hemp; Jessica Chau; Timothy E. Long
Source:
Journal of polymer science 2015 v.53 no.24 pp. 2829-2837
ISSN:
0887-624X
Subject:
caffeine; composite polymers; derivatization; differential scanning calorimetry; glass transition temperature; molecular weight; nuclear magnetic resonance spectroscopy; polymerization; thermoplastics
Abstract:
... The incorporation of acrylic functionality into caffeine enables the preparation of a vast array of novel thermoplastics and thermosets. A two‐step derivatization provided a novel caffeine‐containing methacrylate monomer capable of free radical polymerization. Copolymers of 2‐ethylhexyl methacrylate and caffeine methacrylate (CMA) allowed for a systematic study of the effect of covalently bound ca ...
DOI:
10.1002/pola.27756

44. Hydration of Caffeine at High Temperature by Neutron Scattering and Simulation Studies

Author:
Tavagnacco L.; Brady J. W.; Bruni F.; Callear S.; Ricci M. A.; Saboungi M. L.; Cesàro A.
Source:
Journal of physical chemistry 2015 v.119 no.42 pp. 13294-13301
ISSN:
1520-5207
Subject:
caffeine; chemical interactions; molecular dynamics; temperature
Abstract:
... The solvation of caffeine in water is examined with neutron diffraction experiments at 353 K. The experimental data, obtained by taking advantage of isotopic H/D substitution in water, were analyzed by empirical potential structure refinement (EPSR) in order to extract partial structure factors and site–site radial distribution functions. In parallel, molecular dynamics (MD) simulations were carri ...
DOI:
10.1021/acs.jpcb.5b09204

45. Influence of Coffee Genotype on Bioactive Compounds and the in Vitro Capacity To Scavenge Reactive Oxygen and Nitrogen Species

Author:
Naira Poerner Rodrigues; Terezinha de Jesus Garcia Sahra; Neura Bragagnolo
Source:
Journal of agricultural and food chemistry 2015 v.63 no.19 pp. 4815-4826
ISSN:
0021-8561
Subject:
Coffea arabica; Coffea canephora; antioxidant activity; biological speciation; caffeine; chlorogenic acid; genotype; hydrogen peroxide; hydrophilicity; nitric oxide; nitrogen; oxygen; trigonelline
Abstract:
... The influence of green coffee genotype on the bioactive compounds and the in vitro antioxidant capacity against the principal reactive oxygen (ROO center dot, H2O2, HO center dot, and HOCl) and nitrogen (NO center dot and ONOO-) species of biological relevance was investigated. This is the first report on the capacity of green coffee to scavenge H2O2, HOCl, and NO center dot. Variations in the con ...
DOI:
10.1021/acs.jafc.5b00530

46. Investigation of pharmaceuticals, personal care products and endocrine disrupting chemicals in a tropical urban catchment and the influence of environmental factors

Author:
Luhua You; Viet Tung Nguyen; Amrita Pal; Huiting Chen; Yiliang He; Martin Reinhard; Karina Yew-Hoong Gin
Source:
Science of the total environment 2015 v.536 pp. 955-963
ISSN:
0048-9697
Subject:
acetaminophen; caffeine; chlorophyll; deet; dissolved oxygen; endocrine-disrupting chemicals; environmental assessment; environmental factors; estrone; fipronil; nutrients; personal care products; physicochemical properties; rain; remediation; salicylic acid; surface water; surveys; turbidity; wastewater; watersheds; Singapore
Abstract:
... Previous studies showed the presence of multiple emerging organic contaminants (EOCs) in urban surface waters of Singapore even though there are no obvious direct wastewater discharges. In this study, we investigated the occurrence and distribution of 17 pharmaceuticals and personal care products (PPCPs) and endocrine disruptive compounds (EDCs) in a tropical urban catchment of Singapore. Monthly ...
DOI:
10.1016/j.scitotenv.2015.06.041

47. Investigations of the presence of caffeine in the Rudawa River, Kraków, Poland

Author:
Agnieszka Jagoda; Witold Żukowski; Barbara Dąbrowska
Source:
Environmental monitoring and assessment 2015 v.187 no.9 pp. 566
ISSN:
0167-6369
Subject:
Enterococcus faecalis; Escherichia coli; biochemical oxygen demand; caffeine; gas chromatography-mass spectrometry; isotopes; methanol; nitrates; river water; rivers; sampling; solid phase extraction; surface water; Poland
Abstract:
... Caffeine concentration in surface water (Rudawa River, Kraków, Poland) has been being investigated since 2011. The method applied for investigations was developed in 2011, and the first series of measurements of caffeine concentration in surface water began in 2011. Caffeine concentration was determined by the gas chromatography-mass spectrometry (GC-MS) method. Solid phase extraction (SPE) was us ...
DOI:
10.1007/s10661-015-4760-7
PubMed:
26264791
PubMed Central:
PMC4532709

48. Is tea a healthy source of hydration?

Author:
C. Ruxton; F. Phillips; T. Bond
Source:
Nutrition bulletin 2015 v.40 no.3 pp. 166-176
ISSN:
1471-9827
Subject:
adults; body weight; caffeine; cognition; flavonoids; heart; tea; tea (beverage); United Kingdom
Abstract:
... After water, tea is the most commonly consumed beverage worldwide, with over 80% of adults drinking tea in the UK. Lay concerns about caffeine have led to questions about the suitability of tea as a source of hydration. Several controlled trials have examined the effect of moderate caffeine consumption on fluid balance, from tea or other sources, concluding that intakes of up to 400 mg of caffeine ...
DOI:
10.1111/nbu.12150

49. LC-QTOF MS screening of more than 1,000 licit and illicit drugs and their metabolites in wastewater and surface waters from the area of Bogotá, Colombia

Author:
Félix Hernández; María Ibáñez; Ana-María Botero-Coy; Richard Bade; Martha Cristina Bustos-López; Javier Rincón; Alejandro Moncayo; Lubertus Bijlsma
Source:
Analytical and bioanalytical chemistry 2015 v.407 no.21 pp. 6405-6416
ISSN:
1618-2642
Subject:
acetaminophen; aquatic environment; caffeine; clarithromycin; cocaine; energy; ibuprofen; illicit drugs; ions; lidocaine; lincomycin; metabolites; reference standards; saccharin; screening; solid phase extraction; sucralose; surface water; tandem mass spectrometry; ultra-performance liquid chromatography; wastewater; Colombia
Abstract:
... A large screening of around 1,000 emerging contaminants, focused on licit and illicit drugs and their metabolites, has been made in urban wastewaters (both influent and effluent) and surface waters from the area of Bogotá, Colombia. After a simple generic solid-phase extraction (SPE) step with Oasis hydrophilic-lipophilic balanced (HLB) cartridges, analyses were made by ultra high-performance liqu ...
DOI:
10.1007/s00216-015-8796-x

50. Latex of Euphorbia antiquorum‐induced S‐phase arrest via active ATM kinase and MAPK pathways in human cervical cancer HeLa cells

Author:
Wen‐Tsong Hsieh; Hui‐Yi Lin; Jou‐Hsuan Chen; Wen‐Chung Lin; Yueh‐Hsiung Kuo; W. Gibson Wood; Hsu‐Feng Lu; Jing‐Gung Chung
Source:
Environmental toxicology 2015 v.30 no.10 pp. 1205-1215
ISSN:
1520-4081
Subject:
DNA topoisomerase; Euphorbia antiquorum; Western blotting; ataxia (disorder); caffeine; cell cycle; cyclins; drug therapy; flow cytometry; humans; latex; mitogen-activated protein kinase; neoplasm cells; protein synthesis; signal transduction; uterine cervical neoplasms
Abstract:
... Latex of Euphorbia antiquorum (EA) has demonstrated great chemotherapeutic potential for cancer. However, the mechanisms of anti‐proliferation of EA on cancer cell remain to be further investigated. The purpose of this study was to explore the influence of EA in human cervical cancer cells. Here, the cell cycle distribution by flow cytometry was examined and the protein expression by the western b ...
DOI:
10.1002/tox.21992