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1. "Cool" governance of a "hot" climate issue: public and private responsibilities for the protection of vulnerable citizens against extreme heat

Author:
Heleen L. P. Mees; Peter P. J. Driessen; Hens A. C. Runhaar
Source:
Regional environmental change 2015 v.15 no.6 pp. 1065-1079
ISSN:
1436-3798
Subject:
cities; climate change; elderly; governance; health services; heat; heat stress; issues and policy; mortality; organizations; outreach; temperate zones; urbanization; Europe; North America
Abstract:
... In cities in temperate climate zones, the elderly, disabled and socially deprived are most vulnerable to extreme heat, as witnessed by increased mortality rates during heat waves in Europe and North America. Many cities, however, lag behind in the protection of vulnerable citizens against heat stress, an issue gaining importance in the face of climate change, ongoing urbanization and an ageing pop ...
DOI:
10.1007/s10113-014-0681-1

2. "Decarbonization" of an imino-N-heterocyclic carbene ligand via benzyl migration from hafnium

Author:
Dipesh Prema; Yohan L. N. Mathota Arachchige; Rex E. Murray; LeGrande M. Slaughter
Source:
Chemical communications 2015 v.51 no.31 pp. 6753-6756
ISSN:
1359-7345
Subject:
alkenes; carbon; hafnium; ligands; polymerization
Abstract:
... An imino N-heterocyclic carbene underwent three sequential benzyl migrations upon reaction with tetrabenzylhafnium, resulting in complete removal of the carbene carbon from the ligand. The resulting eneamido-amidinato hafnium complex showed alkene polymerization activity comparable to that of a precatalyst containing the intact iminocarbene ligand. ...
Handle:
10113/62939
DOI:
10.1039/C5CC01560J

3. "Garden walk – on the road to health", a new informative and health-improving route at the Petrozavodsk State University Botanical Garden

Author:
Platonova Elena; Eglacheva Arina; Obuhova Elena; Falin Alexey
Source:
Hortus botanicus 2015 v.10 no.1 pp. -
ISSN:
1994-3849
Subject:
botanical gardens; therapeutics; villages
Abstract:
... The article describes the new informative and health-improving route, "A garden walk - on the road to health", of the Petrozavodsk State University Botanical Garden. The route has been developed for the older generation; however, in the future, citizens and guests of the city of different age groups will be able to take this route. The path goes through the most beautiful and interesting exhibitio ...
DOI:
10.15393/j4.art.2015.3122

4. "Greenhousing": Integrating Low-Input Simplified Hydroponics for Roof Gardening in Bologna's Public Housing

Author:
L. Marchetti; C. Piovene; A. Cesarali; I. Bertocchi; F. Orsini; G. Gianquinto
Source:
Acta horticulturae 2015 v. no.1093 pp. 99-106
ISSN:
0567-7572
Subject:
buildings; cities; containers; ecological footprint; food availability; gardening; gardens; green roofs; hydroponics; landscapes; people; public housing; recycled materials; soil fertility; surface area; therapeutics; urban agriculture; urban horticulture; Italy
Abstract:
... Since 2007, most people of the world live in cities. Urban agriculture, and more specifically urban horticulture may allow improvements in food supply and reduce the city ecological footprint. Furthermore, gardening practices are associated with social and therapeutic effects. In the last decades, as a consequence of the increased awareness on its related benefits, urban horticulture has assumed a ...
DOI:
10.17660/ActaHortic.2015.1093.10

5. "La misma realidad de cada lugar es diferente" ("The same reality of each place is different"): A Case Study of an Organic Farmers Market in Lima, Peru

Author:
Kevin Cody
Source:
Journal of agriculture, food systems, and community development 2015 v.5 no.2 pp. 53-69
ISSN:
2152-0801
Subject:
case studies; developing countries; domestic markets; entrepreneurship; farmers; farmers' markets; livelihood; nongovernmental organizations; organic foods; organic production; rural communities; Europe; North America; Peru
Abstract:
... Studies of alternative food networks have proliferated in Europe and North America while relatively little attention has been paid to similar networks in the global South. An organic farmers market in Lima, Peru, serves as a case study to examine developments in the domestic market for organic produce in Peru. Drawing from interview data and participant observations with pioneering organic farmers ...
DOI:
10.5304/jafscd.2015.052.011

6. "Minimal pruning" in free spindle bush peach trees to avoid an unproductive period

Author:
S. Sansavini; G. Sorrenti; G. L. Del Vecchio
Source:
Acta horticulturae 2015 no.1084 pp. 485-494
ISSN:
0567-7572
Subject:
branches; cutting; fruiting; fruits; orchards; peaches; planting date; pruning; scions; shoots; trees; wood; Italy
Abstract:
... In Italy the “minimal pruning system” (a definition derived from the grapevine pruning technique) is generally utilized in peach orchards. One of its main rules is to initially obtain a “free spindle bush” shape, avoiding cutting back the scion at planting time but using lateral shoots to form future fruiting branches. This experiment involved a comparison of three high density peach plots ...
DOI:
10.17660/ActaHortic.2015.1084.67

7. "To fall or not to fall, that's the question!" molecular mechanisms underlying organ abscission in citrus

Author:
Francisco R. Tadeo; Javier Agusti; Paz Merelo; Leandro H. Estornell; Manuel Cercos; Javier Terol; Concha Domingo; Manuel Talon
Source:
Acta horticulturae 2015 no.1065 pp. 1189-1195
ISSN:
0567-7572
Subject:
crop production; citrus fruits; abscission; cell walls; industry; seed dispersal; breeding; genes; Citrus; cell adhesion; genetic markers; mechanical harvesting
Abstract:
... During their life cycle, citrus plants can experience different processes involving separation of cells by dissolution of cell adhesion materials and breakdown of cell walls at specific sites on the plant body. Abscission enables both vegetative and reproductive organs to be shed in response to developmental, hormonal and environmental cues. From an evolutionary point of view, abscission is a high ...

8. "We Just Have To Continue Working": Farmworker Self-care and Heat-related Illness

Author:
Michael D. Courville; Gail Wadsworth; Marc Schenker
Source:
Journal of agriculture, food systems, and community development 2015-2016 v.6 no.2 pp. 143-164
ISSN:
2152-0801
Subject:
farm labor; farms; focus groups; heat; industry; summer; working conditions; California
Abstract:
... Heat-related illness (also called heat illness) is a recurring and avoidable condition that results in multiple deaths in California farm fields every year. We conducted five focus groups as part of the California Heat Illness Prevention Study (CHIPS) in Fresno, California, during the summer of 2013. We used qualitative coding methods to analyze focus group transcript data with consideration of wo ...
DOI:
10.5304/jafscd.2016.062.014

9. #LivingOffTips: Reframing Food System Labor Through Tipped Workers' Narratives of Subminimum Wage Exploitation

Author:
Kathleen P. Hunt
Source:
Journal of agriculture, food systems, and community development 2015-2016 v.6 no.2 pp. 165-177
ISSN:
2152-0801
Subject:
advocacy; consumers (people); farm labor; females; qualitative analysis; restaurants; risk; slaughter; social inequality; social networks
Abstract:
... Agrifood movement literature largely represents food system labor through images, descriptions, and depictions of farm workers and other agriculture-related labor, such as slaughtering and meatpacking. Although engaging in a holistic dialogue that considers the continuum of labor abuse across the food system may be a difficult task, privileging production-oriented food system labor reinforces what ...
DOI:
10.5304/jafscd.2016.062.021

10. 'Candidatus Phytoplasma prunorum' - a pathogen spreading uncontrollably in apricot orchards in the Czech Republic

Author:
T. Necas; I. Ondrasek; B. Krska
Source:
Acta horticulturae 2015 no.1105 pp. 131-136
ISSN:
0567-7572
Subject:
Phytoplasma; apricots; biotic factors; cultivars; fungi; leaves; monitoring; mortality; orchards; pathogens; phytoplasmal diseases; tree mortality; trees; Czech Republic
Abstract:
... Tree mortality of apricots involves many abiotic and biotic factors. The most important biotic factors include bacterial, fungal and viral diseases and especially phytoplasmas. Generally it is very difficult to determine the primary pathogen causing premature mortality in trees of apricot. However, according to long-term monitoring of apricot orchards in the Czech Republic (South Moravian region), ...
DOI:
10.17660/ActaHortic.2015.1105.19

11. 'EnSpray 99' Mineral Oils for White Peach Scale, Pseudaulacaspis pentagona and Phytotoxicity to 'Hongyang' Kiwifruit

Author:
Q. G. Zhuang; L. H. Wang; M. Z. Li; T. P. Hou; Y. Xie
Source:
Acta horticulturae 2015 v. no.1096 pp. 363-370
ISSN:
0567-7572
Subject:
Pseudaulacaspis pentagona; fruit set; instars; kiwifruit; mineral oil; phytotoxicity; plant damage
Abstract:
... ‘EnSpray 99’ mineral oil has good efficacy against first instar Pseudaulacaspis pentagona and its residues prevented crawler settlement for approximate 12 days after oil application. Oil application was safe when applied to ‘Hongyang’ kiwifruit to control P. pentagona at the first generation 1st instar (4-18 days after fruit set). 1% oil application during the second generation crawler pea ...
DOI:
10.17660/ActaHortic.2015.1096.42

12. 'Faith', 'Gratitude', 'Hope', and 'Joy' seedless table grapes from Arkansas, USA

Author:
J. R. Clark; J. N. Moore
Source:
Acta horticulturae 2015 no.1082 pp. 87-93
ISSN:
0567-7572
Subject:
Vitis; climate; color; cultivars; flavor; fruit cracking; growers; hardness; harvest date; hybrids; markets; new variety; retail marketing; ripening; small fruits; table grapes; texture; vines; winter hardiness; Arkansas
Abstract:
... ‘Faith’, ‘Gratitude’ ‘Hope’, and ‘Joy’ seedless table grapes are new cultivars (Vitis hybrid) developed by the University of Arkansas Division of Agriculture, bringing to 12 the total number of releases from the program. These releases expand options for table grape growers for local markets in the United States. All four cultivars have non-slipskin flesh with good skin quality, fr ...
DOI:
10.17660/ActaHortic.2015.1082.11

13. 'Green Care' in Poland - Application of Horticulture for Improvement of Human Life Quality and Environment Protection

Author:
M. J. Latkowska
Source:
Acta horticulturae 2015 v. no.1093 pp. 125-131
ISSN:
0567-7572
Subject:
biodiversity; case studies; farms; food processing; fruit growing; health services; homeless people; humans; nongovernmental organizations; organic production; people with disabilities; quality of life; therapeutics; vegetable growing; villages; Poland
Abstract:
... ‘Green care’ is a special form of application of horticulture and farming in therapy and social care for the disadvantaged people. The aim of the study was to characterize model pioneer ‘green care’ initiatives in Poland. Data collected during the study visits was used to elaborate case studies of five ‘care farms’. Centres studied differ in their area (from 4.5 ha to 1,900 ha), howeve ...
DOI:
10.17660/ActaHortic.2015.1093.13

14. 'Malihabadi dashehari' mango geographical indication - a case study

Author:
N. Bhooshan; R. Dutta; S. Singh
Source:
Acta horticulturae 2015 no.1066 pp. 219-226
ISSN:
0567-7572
Subject:
business planning; case studies; crops; cultivars; farmers; fruits; mangoes; markets; monopoly; protected designation of origin; India
Abstract:
... Intellectual property is all about monopoly in the market place and harnessing the maximum economic benefits by exercising the monopoly. Monopoly in the shape of goodwill, reputation and demand becomes the most formidable under the banner of Geographical Indication (GI) as GI is a monopoly of a guild unlike a private monopoly. Uttar Pradesh is a sacred land as the birth place of Lord Ram and Lord ...

15. 'Marge': a European Elderberry for North American producers

Author:
A. L. Thomas; P. L. Byers; J. D. Jr. Avery; M. Kaps; S. Gu; H. Y. Johnson; M. Millican
Source:
Acta horticulturae 2015 no.1061 pp. 191-199
ISSN:
0567-7572
Subject:
Sambucus canadensis; budbreak; cultivars; drought tolerance; elderberries; flowers; fruits; genetic markers; genotype; horticultural crops; mites; open pollination; pruning; seedlings; wood; Europe; Missouri
Abstract:
... Elderberries are being increasingly produced and consumed in North America for their edible and medicinal flowers and fruits. The American elderberry (Sambucus nigra subsp. Canadensis) is native to, and most often cultivated in North America. The European elderberry (S. nigra subsp. nigra) has been developed into an economically-important horticultural crop in Europe, but most European cultivars d ...

16. 'Omics' and chemical approaches used to monitor iron-deficiency in citrus rootstocks

Author:
Concetta Licciardello; Vera Muccilli; Biagio Torrisi; Paola Tononi; Debora Fontanini; Maria Allegra; Fabiola Sciacca; Salvatore Foti; Massimo Delledonne; Francesco Intrigliolo; Giuseppe Reforigiato Recupero
Source:
Acta horticulturae 2015 v. no.1065 pp. 1293-1301
ISSN:
0567-7572
Subject:
Citroncirus webberi; Citrus; auxins; chlorophyll; gene expression regulation; genes; glutamate dehydrogenase; glutathione peroxidase; iron; neutralization; nutrient deficiencies; peroxidase; phosphofructokinases; protein synthesis; proteomics; roots; rootstocks; soil; transcriptomics; two-dimensional gel electrophoresis
Abstract:
... Two different ‘omics’ approaches were performed to a better comprehension of biological mechanisms involved in citrus iron (Fe) deficiency. Tips roots from Swingle citrumelo and Carrizo citrange (sensitive and tolerant rootstocks, respectively), growing in pots with control and chlorotic soil, were used for transcriptomic and proteomic analysis. CombiMatrix array was performed to isolate diffe ...

17. 'Rebolla 1' peach cultivar: late ripening and leaf curl (Taphrina deformans - Berkeley) resistant

Author:
V. Nencetti; D. Morelli; E. Bellini
Source:
Acta horticulturae 2015 no.1084 pp. 139-142
ISSN:
0567-7572
Subject:
Taphrina deformans; acids; breeding; cultivars; environmental science; flowering; flowers; leaf curling; leaves; peaches; ripening; sugars
Abstract:
... The cultivar “Rebolla 1” was obtained from a leaf curl (Taphrina deformans - Berkeley) resistance breeding program, started in the 1990s at DOFI, today the Department of Agri-Food and Environmental Science (DiSPAA) at the University of Florence. It is a late ripening, white peach with medium-high resistance to T. deformans (class 2: from a few up 10% infected leaves). It is also characterized ...
DOI:
10.17660/ActaHortic.2015.1084.17

18. 'Sweet Sicily' and 'Early Sicily', two new triploids from the program of CRA-research Centre of Citriculture and Mediterranean crops

Author:
Giuseppe Russo; Giuseppe Reforgiato Recupero; Santo Recupero; Donata Pietro Paolo
Source:
Acta horticulturae 2015 v. no.1065 pp. 215-221
ISSN:
0567-7572
Subject:
blood; clementines; crops; crossing; females; fresh market; fruits; harvesting; hybrids; males; parents; ripening; sensory properties; taste; triploidy; Sicily
Abstract:
... Since 1978 the development of triploid hybrids by crossing monoembryonic 2x female parents with 4x male parents has been the successful breeding strategy carried out by the CRA-ACM. Through this strategy hybrids issued in the past allowed the obtainment of seedless fruits, in some cases pigmented, of good size and maturation in different periods. In 2011 other two promising hybrids, ‘Sweet Sicil ...

19. 'Taishanhong' Pomegranate and Its Cultivation Techniques with High Yield and Good Quality

Author:
Kun Ran; Xiaoli Sun; Shaomin Wang
Source:
Acta horticulturae 2015 v. no.1089 pp. 263-267
ISSN:
0567-7572
Subject:
cultivars; flowers; frost; fruit yield; harvesting; industrialization; orchards; pest control; pomegranates; water management; China
Abstract:
... Pomegranate is a kind of excellent fruit with economic, ecologic and health functions, which originated in the central Asian region and has been cultivated more than two thousand years in China. This paper summarizes the characteristics of ‘Taishanhong’ pomegranate, one of the preferable cultivars of pomegranate at present in China, and its cultivation techniques for achieving high yield and f ...
DOI:
10.17660/ActaHortic.2015.1089.34

20. (+)- and (−)-Pestaloxazine A, a Pair of Antiviral Enantiomeric Alkaloid Dimers with a Symmetric Spiro[oxazinane-piperazinedione] Skeleton from Pestalotiopsis sp.

Author:
Jia Yan-Lai; Wei Mei-Yan; Chen Hai-Yan; Guan Fei-Fei; Wang Chang-Yun; Shao Chang-Lun
Source:
Organic letters 2015 v.17 no.17 pp. 4216-4219
ISSN:
1523-7052
Subject:
Pestalotiopsis; X-ray diffraction; alkaloids; antiviral properties; chemical reactions; chemical structure; corals; fungi; high performance liquid chromatography; inhibitory concentration 50; spectroscopy
Abstract:
... A pair of new enantiomeric alkaloid dimers, (+)- and (−)-pestaloxazine A (1), with an unprecedented symmetric spiro[oxazinane-piperazinedione] skeleton, consisting of 22 carbons and 12 heteroatoms, were isolated from a Pestalotiopsis sp. fungus derived from a soft coral. Separation of the enantiomeric alkaloid dimers was achieved by chiral HPLC. Their structures including absolute configurations w ...
DOI:
10.1021/acs.orglett.5b01995

21. (+)- and (−)-Petromyroxols: Antipodal Tetrahydrofurandiols from Larval Sea Lamprey (Petromyzon marinus L.) That Elicit Enantioselective Olfactory Responses

Author:
Li Ke; Huertas Mar; Brant Cory; Chung-Davidson Yu-Wen; Bussy Ugo; Hoye Thomas R.; Li Weiming
Source:
Organic letters 2015 v.17 no.2 pp. 286-289
ISSN:
1523-7052
Subject:
Petromyzon marinus; chemical reactions; chromatography; enantiomers; enantioselectivity; fatty acids; larvae; synthetic products; tetrahydrofuran
Abstract:
... (+)- and (−)-Petromyroxol [(+)-1 and (−)-1, respectively], two novel tetrahydrofuran (THF)-diol fatty acid enantiomers, were isolated from water conditioned with larval sea lamprey. We herein describe their isolation and subsequent resolution using chiral chromatography. The absolute configuration of each enantiomer was determined by a combination of Mosher ester analysis and comparison with relat ...
DOI:
10.1021/ol5033893

22. (+)- and (−)-Spiroreticulatine, A Pair of Unusual Spiro Bisheterocyclic Quinoline-imidazole Alkaloids from the South China Sea Sponge Fascaplysinopsis reticulata

Author:
Wang Qi; Tang Xuli; Luo Xiangchao; de Voogd Nicole J.; Li Pinglin; Li Guoqiang
Source:
Organic letters 2015 v.17 no.14 pp. 3458-3461
ISSN:
1523-7052
Subject:
X-ray diffraction; alkaloids; chemical reactions; chemical structure; interleukin-2; neoplasm cells; spectral analysis; tryptophan; South China Sea
Abstract:
... A pair of novel bisheterocyclic quinoline-imidazole alkaloids, (+)- and (−)-spiroreticulatine (1), were isolated from the South China Sea sponge Fascaplysinopsis reticulata. The structures and absolute configurations were elucidated by comprehensive spectroscopic analysis, single-crystal X-ray diffraction, and quantum chemical calculation methods. Spiroreticulatine is the first example of a sponge ...
DOI:
10.1021/acs.orglett.5b01503

23. (+)-(6aR,7R)-7-Hydroxy-N-Butyrylcaaverine, a New Aporphine Alkaloid from the Roots of Illigera luzonensis with Cytotoxic Activity

Author:
Jih-Jung Chen; Tzong-Huei Lee; Wen-Lung Kuo; Ping-Jyun Sung; Ih-Sheng Chen; Chih-Wen Shu; Ming-Jen Cheng; Tai-Chi Wang; Yun-Ping Lim; Rong Xu
Source:
Chemistry of natural compounds 2015 v.51 no.4 pp. 739-742
ISSN:
0009-3130
Subject:
alkaloids; chemistry; cytotoxicity; roots; spectroscopy
Abstract:
... A new aporphine alkaloid, (+)-(6aR,7R)-7-hydroxy-N-butyrylcaaverine (1), has been isolated from the roots of Illigera luzonensis. The structure of the new compound 1 was determined through spectroscopic and MS analyses. ...
DOI:
10.1007/s10600-015-1397-2

24. (+)-Epogymnolactam, a novel autophagy inducer from mycelial culture of Gymnopus sp.

Author:
Shinya Mitsuhashi; Chihaya Shindo; Kengo Shigetomi; Toshizumi Miyamoto; Makoto Ubukata
Source:
Phytochemistry 2015 v.114 pp. 163-167
ISSN:
0031-9422
Subject:
Ganoderma lucidum; autophagy; bioactive properties; human diseases; methanol; mushrooms; mycelium; nuclear magnetic resonance spectroscopy; screening
Abstract:
... Mushrooms, including Ganoderma lucidum, have been used as a potential source of therapeutic compounds, and an autophagy inducer would be useful for treatment of diverse diseases in human. Reported here is a full account of screening, isolation, structural determination, and biological activity of an autophagy inducer, (+)-epogymnolactam (1) from a mycelial culture of a Gymnopus sp. strain. Its str ...
DOI:
10.1016/j.phytochem.2014.08.012

25. (1,2-Diaminoethane-1,2-diyl)bis(N-methylpyridinium) Salts as a Prospective Platform for Designing Recyclable Prolinamide-Based Organocatalysts

Author:
Lisnyak Vladislav G.; Kucherenko Alexander S.; Valeev Edward F.; Zlotin Sergei G.
Source:
Journal of organic chemistry 2015 v.80 no.19 pp. 9570-9577
ISSN:
1520-6904
Subject:
catalysts; chemical reactions; chemical structure; organic chemistry; organic compounds; salts
Abstract:
... A new efficient and highly recyclable organocatalyst has been developed for asymmetric cross-aldol reactions under neat conditions in ketone–ketone, ketone–aldehyde, and aldehyde–aldehyde systems. The catalyst features two prolinamide fragments and a C₂-symmetrical (1,2-diaminoethane-1,2-diyl)bis(N-methylpyridinium) group. The catalyst retained high activity and excellent stereoselection over the ...
DOI:
10.1021/acs.joc.5b01555

26. (100) surface-exposed CeO₂ nanocubes as an efficient heterogeneous catalyst in the tandem oxidation of benzyl alcohol, para-chlorobenzyl alcohol and toluene to the corresponding aldehydes selectively

Author:
Kalyanjyoti Deori; Chinmoy Kalita; Sasanka Deka
Source:
Journal of materials chemistry A 2015 v.3 no.13 pp. 6909-6920
ISSN:
2050-7496
Subject:
benzaldehyde; benzyl alcohol; catalysts; catalytic activity; ceric oxide; crystal structure; nanocrystals; nanorods; oxidation; oxygen; porosity; surface area; toluene
Abstract:
... A new synthesis strategy has been developed to synthesize exclusively (100)-surface-exposed CeO₂ nanocubes (∼90 nm), formed through three dimensional (3D) self-assembly of smaller ceria nanocrystal building blocks, as an efficient heterogeneous catalyst for multiple selective oxidation reactions. To compare the effect of morphology on catalysis, 1D CeO₂ nanorods have also been tested in parallel. ...
DOI:
10.1039/c4ta06547f

27. (1S,3R,4S,5R)5-O-Caffeoylquinic acid: Isolation, stereo-structure characterization and biological activity

Author:
Martino Forino; Gian Carlo Tenore; Luciana Tartaglione; Dell’Aversano Carmela; Ettore Novellino; Patrizia Ciminiello
Source:
Food chemistry 2015 v.178 pp. 306-310
ISSN:
0308-8146
Subject:
Sorbus domestica; antioxidants; bioactive properties; butanol; chemical analysis; chlorogenic acid; cholesterol; diabetes; fruits; glucose; medicine; nuclear magnetic resonance spectroscopy; polyphenols; stereoisomers; Italy
Abstract:
... Sorbus domestica fruits (sorbs) are commonly harvested and consumed for their nutritious qualities and have long been used as natural remedy against diabetes in the popular medicine. Recently, sorbs have been described as sources of antioxidant compounds including polyphenols. Chemical analyses carried out on sorbs collected in Southern Italy have led to the isolation of a chlorogenic acid isomer ...
DOI:
10.1016/j.foodchem.2015.01.109

28. (1→3)-α-d-Glucan hydrolases in dental biofilm prevention and control: A review

Author:
Małgorzata Pleszczyńska; Adrian Wiater; Monika Janczarek; Janusz Szczodrak
Source:
International journal of biological macromolecules 2015 v.79 pp. 761-778
ISSN:
0141-8130
Subject:
biofilm; hydrolases; microbiome; mouth diseases; pathogens; polysaccharides
Abstract:
... Dental plaque is a highly diverse biofilm, which has an important function in maintenance of oral and systemic health but in some conditions becomes a cause of oral diseases. In addition to mechanical plaque removal, current methods of dental plaque control involve the use of chemical agents against biofilm pathogens, which however, given the complexity of the oral microbiome, is not sufficiently ...
DOI:
10.1016/j.ijbiomac.2015.05.052

29. (1→3)-β-d-Glucan oligosaccharides monomers purification and its H2O2 induction effect study

Author:
Yunbin Fu; Mengyu Wang; Wenxia Wang; Yaqin Tuo; Zhimou Guo; Yuguang Du; Heng Yin
Source:
International journal of biological macromolecules 2015 v.81 pp. 1069-1073
ISSN:
0141-8130
Subject:
bioactive properties; desorption; hydrogen peroxide; hydrophilic interaction chromatography; ionization; matrix-assisted laser desorption-ionization mass spectrometry; oligosaccharides; polymerization; tobacco
Abstract:
... In order to produce highly purified (1→3)-β-d-glucan oligosaccharides ((1→3)-β-d-GOS) monomers, a hydrophilic interaction liquid chromatography (HILIC) system with X-Amide stationary phase was performed. Nine (1→3)-β-d-GOS monomers with degree of polymerization (DP) from 2 to 10 were successfully separated. Matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) ...
DOI:
10.1016/j.ijbiomac.2015.09.028

30. (1→6)- and (1→3)(1→6)-β-glucans from Lasiodiplodia theobromae MMBJ: Structural characterization and pro-inflammatory activity

Author:
Kassandra S.M. Oliveira; Mirela Di Bastiani; Lucimara M.C. Cordeiro; Mírian F. Costa; Karina A. Toledo; Marcello Iacomini; Aneli M. Babosa; Robert F.H. Dekker; Valéria M.G. Nascimento
Source:
Carbohydrate polymers 2015 v.133 pp. 539-546
ISSN:
0144-8617
Subject:
Lasiodiplodia theobromae; beta-glucans; chemical composition; cold; exopolysaccharides; fungi; immunomodulation; inflammation; macrophages; molecular weight; submerged fermentation
Abstract:
... The chemical composition and structural characterization of exopolysaccharides from the fungus Lasiodiplodia theobromae MMBJ are described, and the immunomodulatory activity of a purified β-glucan was evaluated. L. theobromae MMBJ produced three different β-glucans. One, fraction PEPS, was a branched (1→3)(1→6)-β-glucan and was insoluble in cold water. The other two, fractions SEPS-005R and SEPS-1 ...
DOI:
10.1016/j.carbpol.2015.07.060

31. (2 + 2) Cycloaddition of Benzyne to Endohedral Metallofullerenes M3N@C80 (M = Sc, Y): A Rotating-Intermediate Mechanism

Author:
Yang Tao; Nagase Shigeru; Akasaka Takeshi; Poblet Josep M.; Houk K. N.; Ehara Masahiro; Zhao Xiang
Source:
Journal of the American Chemical Society 2015 v.137 no.21 pp. 6820-6828
ISSN:
1520-5126
Subject:
cycloaddition reactions; energy; fullerene; thermodynamics
Abstract:
... The reaction mechanism and origin of regioselectivity of (2 + 2) cycloadditions of benzyne to endohedral metallofullerenes M₃N@C₈₀ (M = Sc, Y) were investigated with density functional calculations. The reaction was demonstrated to follow a diradical mechanism rather than a carbene mechanism, in which the formation of the diradical intermediate is the rate-determining step. Through rotation of ben ...
DOI:
10.1021/jacs.5b01444

32. (2-Chlorobenzoyloxy)copper(i) catalyzed C–S cross-coupling of di(hetero)aryl disulfides with aryl boronic acids under base-free conditions

Author:
Yan Guo; Zheng-Jun Quan; Yu-Xia Da; Zhang Zhang; Xi-Cun Wang
Source:
RSC advances 2015 v.5 no.56 pp. 45479-45483
ISSN:
2046-2069
Subject:
aromatic compounds; boronic acids; catalytic activity; copper; cross-coupling reactions; disulfides; heterocyclic compounds; organic sulfur compounds
Abstract:
... (2-Chlorobenzoyloxy)copper(i) exhibited high activity towards the challenging C–S cross-coupling of di(hetero)aryl disulfides with aryl boronic acids. Herein, diheteroaryl as well as diaryl thioethers were produced with good to excellent yields under base-free conditions. ...
DOI:
10.1039/c5ra05594f

33. (2R,3S)-Pinobanksin-3-cinnamate improves cognition and reduces oxidative stress in rats with vascular dementia

Author:
Hong Liu; Min Zhao; Shen Yang; Dian-Rong Gong; De-Zhe Chen; De-Yong Du
Source:
Natural medicines 2015 v.69 no.3 pp. 358-365
ISSN:
1340-3443
Subject:
carotid arteries; caspases; cognition; cytochrome c; dementia; glutathione; malondialdehyde; neuroprotective effect; oxidative stress; protein synthesis; rats; superoxide dismutase
Abstract:
... This study investigated the neuroprotective effects of (2R,3S)-pinobanksin-3-cinnamate (PNC) in rats with occlusion-damaged bilateral common carotid arteries. Administration with PNC (5 and 10 mg/kg/day) for 5 weeks significantly improved the behavioral performance of rats with vascular dementia, as showed in the Morris water maze test by shortening the escape latency and latency of crossing, comp ...
DOI:
10.1007/s11418-015-0901-0

34. (2S)-7,4′-dihydroxy-8-prenylflavan stimulates adipogenesis and glucose uptake through p38MAPK pathway in 3T3-L1 cells

Author:
Jun Ji; Jingjie Zhu; Xiao Hu; Ting Wang; Xiaodong Zhang; Ai-Jun Hou; Heyao Wang
Source:
Biochemical and biophysical research communications 2015 v.460 pp. 578-582
ISSN:
0006-291X
Subject:
Western blotting; adipogenesis; adiponectin; adipose tissue; genes; glucose; glucose transporters; lipids; mitogen-activated protein kinase; noninsulin-dependent diabetes mellitus; obesity; quantitative polymerase chain reaction; tumor necrosis factor-alpha
Abstract:
... Adipose tissue plays a key role in the development of obesity and diabetes. Natural products are one of the main sources for discovering new lead compounds. In the present study, (2S)-7,4′-dihydroxy-8-prenylflavan (DHPF), a natural prenylated flavan isolated from Morus yunnanensis, was found to significantly promote adipogenesis and increase glucose uptake in 3T3-L1 cells. Real-time PCR results sh ...
DOI:
10.1016/j.bbrc.2015.03.072

35. (2S,4E)-2-Hydroxy-4-octen-3-one, a Male-Produced Attractant Pheromone of the Cerambycid Beetle Tylonotus bimaculatus

Author:
Yunfan Zou; Jocelyn G. Millar; J. Scott Blackwood; Ryan Van Duzor; Lawrence M. Hanks; Judith A. Mongold-Diers; Joseph C. H. Wong; Ann M. Ray
Source:
Journal of chemical ecology 2015 v.41 no.7 pp. 670-677
ISSN:
0098-0331
Subject:
Cerambycidae; adults; bioassays; indigenous species; males; pheromones; North America
Abstract:
... We report the identification of a novel pheromone structure from males of the cerambycid beetle Tylonotus bimaculatus Haldeman (Cerambycinae: Hesperophanini), a species native to eastern North America. Volatiles collected from adult males contained (2S,4E)-2-hydroxyoct-4-en-3-one (71 %), (3R,4E)-3-hydroxyoct-4-en-2-one (15 %), (E)-4-octen-2,3-dione (13 %), and 2,3-octanedione (1.5 %). Four indepen ...
DOI:
10.1007/s10886-015-0603-9

36. (3E,7E)-3,7-Bis(2-oxoindolin-3-ylidene)-5,7-dihydropyrrolo[2,3-f]indole-2,6(1H,3H)-dione based polymers for ambipolar organic thin film transistors

Author:
Yinghui He; Chang Guo; Bin Sun; Jesse Quinn; Yuning Li
Source:
Chemical communications 2015 v.51 no.38 pp. 8093-8096
ISSN:
1364-548X
Subject:
chemical reactions; films (materials); polymers; transistors
Abstract:
... A novel acceptor, (3E,7E)-3,7-bis(2-oxoindolin-3-ylidene)-5,7-dihydropyrrolo[2,3-f]indole-2,6(1H,3H)-dione, was reported. Donor–acceptor (D–A) polymer semiconductors using this new building block showed high ambipolar charge transport performance with hole and electron mobilities up to 0.19 and 0.09 cm² V⁻¹ s⁻¹, respectively, in thin film transistors. ...
DOI:
10.1039/c5cc01021g

37. (3E,8E)-3,8-Bis(2-oxoindolin-3-ylidene)naphtho-[1,2-b:5,6-b′]difuran-2,7(3H,8H)-dione (INDF) based polymers for organic thin-film transistors with highly balanced ambipolar charge transport characteristics

Author:
Yunfeng Deng; Bin Sun; Yinghui He; Jesse Quinn; Chang Guo; Yuning Li
Source:
Chemical communications 2015 v.51 no.70 pp. 13515-13518
ISSN:
1364-548X
Subject:
chemical reactions; films (materials); polymers; transistors
Abstract:
... Two donor–acceptor (D–A) conjugated polymers, PINDFTT and PINDFBT, based on a novel electron acceptor, (3E,8E)-3,8-bis(2-oxoindolin-3-ylidene)naphtho-[1,2-b:5,6-b′]difuran-2,7(3H,8H)-dione (INDF), are synthesized for solution processed organic thin-film transistors. Both polymers exhibited highly balanced ambipolar characteristics with hole and electron mobilities up to 0.51 cm² V⁻¹ s⁻¹ and 0.50 c ...
DOI:
10.1039/c5cc03917g

38. (6E) and (6Z)-9′-Aporhodoxanthinone, novel carotenoids produced in zeaxanthin-synthesizing-Escherichia coli by redox stress

Author:
Miho Takemura; Takashi Maoka; Ayako Osawa; Haruka Higashinaka; Hiroshi Shimada; Kazutoshi Shindo; Norihiko Misawa
Source:
Tetrahedron letters 2015 v.56 pp. 6063-6065
ISSN:
0040-4039
Subject:
Escherichia coli; Haematococcus pluvialis; Pantoea ananatis; aeration; bacteria; beta-carotene; beta-cryptoxanthin; chemical structure; genes; nuclear magnetic resonance spectroscopy; photooxidation; spectral analysis; ultraviolet-visible spectroscopy; zeaxanthin
Abstract:
... Recombinant Escherichia coli, carrying the crtE, crtB, crtI, crtY, and crtZ genes from the bacterium Pantoea ananatis in addition to the Haematococcus pluvialis idi gene, can dominantly produce zeaxanthin. Vigorous rotary-shaking culture of the recombinant cells to promote strong aeration led to the production of two structurally similar polar carotenoids [1 (3.7%) and 2 (2.9%)] and eschscholtzxan ...
DOI:
10.1016/j.tetlet.2015.09.058

39. (7E,11E)-3,5,9,11-Tetramethyltridecadienal: Sex Pheromone of the Strepsipteran Xenos peckii

Author:
Michael Hrabar; Huimin Zhai; Regine Gries; Paul W. Schaefer; Jason Draper; Robert Britton; Gerhard Gries
Source:
Journal of chemical ecology 2015 v.41 no.8 pp. 732-739
ISSN:
0098-0331
Subject:
Polistes fuscatus; Stylops; abdomen; antennae; bait traps; biochemical pathways; females; field experimentation; hexane; males; nuclear magnetic resonance spectroscopy; parasitoids; sex pheromones
Abstract:
... Xenos peckii is a strepsipteran parasitoid of the common North American paper wasp, Polistes fuscatus. Mate-seeking X. peckii males respond to a long-range sex pheromone emitted by the female, which remains permanently embedded within the abdomen of a mobile host wasp. During peak pheromone signalling, we excised the female from her host, severed the cephalothorax containing the pheromone gland, e ...
DOI:
10.1007/s10886-015-0613-7

40. (Ag,Cu)–Ta–O Ternaries As High-Temperature Solid-Lubricant Coatings

Author:
Gao Hongyu; Otero-de-la-Roza Alberto; Gu Jingjing; Stone D’Arcy; Aouadi Samir M.; Johnson Erin R.; Martini Ashlie
Source:
ACS Applied Materials & Interfaces 2015 v.7 no.28 pp. 15422-15429
ISSN:
1944-8252
Subject:
coatings; copper; energy; friction; lubricants; methodology; molecular dynamics; oxides; silver; temperature
Abstract:
... Ternary oxides have gained increasing attention due to their potential use as solid lubricants at elevated temperatures. In this work, the tribological properties of three ternary oxidesAgTaO₃, CuTaO₃, and CuTa₂O₆were studied using a combination of density-functional theory (DFT), molecular dynamics (MD) simulations with newly developed empirical potential parameters, and experimental measuremen ...
DOI:
10.1021/acsami.5b03543

41. (Arylimido)vanadium(V)–Alkylidene Complexes Containing Fluorinated Aryloxo and Alkoxo Ligands for Fast Living Ring-Opening Metathesis Polymerization (ROMP) and Highly Cis-Specific ROMP

Author:
Hou Xiaohua; Nomura Kotohiro
Source:
Journal of the American Chemical Society 2015 v.137 no.14 pp. 4662-4665
ISSN:
1520-5126
Subject:
catalytic activity; ligands; molecular weight; polymerization; polymers; vanadium
Abstract:
... (Arylimido)vanadium(V)–alkylidene complexes, V(CHSiMe₃)(N-2,6-X₂C₆H₃)(OC₆F₅)(PMe₃)₂ [X = Me (2), Cl (4)], exhibited remarkable catalytic activities for ring-opening metathesis polymerization (ROMP) of norbornene, and the ROMP by 2 proceeded in a living manner, affording ultrahigh molecular weight polymers. Cis-specific ROMP was achieved with the alkoxo analogues, V(CHSiMe₃)(N-2,6-X₂C₆H₃)[OC(CH₃)(C ...
DOI:
10.1021/jacs.5b02149

42. (Carboxy-3-oxopropylamino)-3-propylsilylcellulose as a novel organocatalyst for the synthesis of substituted imidazoles under solvent-free conditions

Author:
Mehri Salimi; Mohammad Ali Nasseri; Tayyebeh Daliran Chapesshloo; Batol Zakerinasab
Source:
RSC advances 2015 v.5 no.43 pp. 33974-33980
ISSN:
2046-2069
Subject:
aldehydes; amines; ammonium acetate; anhydrides; cellulose; imidazoles; moieties; organocatalysts
Abstract:
... (Carboxy-3-oxopropylamino)-3-propylsilylcellulose (COPAPSC), a novel organocatalyst, has been prepared by a synthesis grafting of –COOH functionalized organosilanes on a cellulose using surface hydroxyl groups as anchor points. The –CO₂H group-functionalized cellulose was synthesized via the consecutive surface functionalization with 3-aminopropyltriethoxysilane (3-APTES) followed by the condensat ...
DOI:
10.1039/c5ra01909e

43. (Chemo)enzymatic cascades—Nature's synthetic strategy transferred to the laboratory

Author:
Eduardo García-Junceda; Iván Lavandera; Dörte Rother; Joerg H. Schrittwieser
Source:
Journal of molecular catalysis 2015 v.114 pp. 1-6
ISSN:
1381-1177
Subject:
biocatalysis; chemists; researchers
Abstract:
... The astonishing efficiency with which living organisms build complex molecules from simple starting materials has inspired chemists for centuries. Among the synthetic strategies that nature uses to achieve this efficiency, the combination of several enzymatic transformations in cascading sequences is of outstanding importance. With the rise of biocatalysis, researchers now have the tools at hand t ...
DOI:
10.1016/j.molcatb.2014.12.007

44. (De)growth and welfare in an equilibrium model with heterogeneous consumers

Author:
T. Heikkinen
Source:
Ecological economics 2015 v.116 pp. 330-340
ISSN:
0921-8009
Subject:
consumer economics; ecological economics; simulation models; socioeconomic development; socioeconomic status
Abstract:
... This paper studies equilibrium growth and voluntary degrowth, allowing for heterogeneous and time-varying preferences. The approach is based on applying a dynamic equilibrium model with externalities in production, consumption, and leisure. Preference heterogeneity regarding status competition is modeled by asymmetric consumption externality parameters whereas heterogeneity regarding voluntary sim ...
DOI:
10.1016/j.ecolecon.2015.05.005

45. (Diacetoxyiodo)benzene-Mediated Reaction of Ethynylcarbinols: Entry to α,α′-Diacetoxy Ketones and Glycerol Derivatives

Author:
Liu Qing-Rong; Pan Cheng-Xue; Ma Xiao-Pan; Mo Dong-Liang; Su Gui-Fa
Source:
Journal of organic chemistry 2015 v.80 no.12 pp. 6496-6501
ISSN:
1520-6904
Subject:
chemistry; glycerol; ketones
Abstract:
... Efficient access to α,α′-diacetoxy ketones has been developed from ethynylcarbinols and PhI(OAc)₂. A plausible mechanism for this was proposed on the basis of experimental studies. The usefulness of α,α′-diacetoxy ketone products has been documented, and glycerol derivatives can be easily synthesized in good yields via a one-pot reaction. ...
DOI:
10.1021/acs.joc.5b00740

46. (E)-Specific direct Julia-olefination of aryl alcohols without extra reducing agents promoted by bases

Author:
Chuan-Zhi Yao; Qiang-Qiang Li; Mei-Mei Wang; Xiao-Shan Ning; Yan-Biao Kang
Source:
Chemical communications 2015 v.51 no.36 pp. 7729-7732
ISSN:
1364-548X
Subject:
alcohols; aldehydes; alkenes; aromatic compounds; chemical reactions; hydrides; reducing agents
Abstract:
... An unprecedented base-promoted direct olefination of aryl alcohols with sulfones via a Julia-type reaction has been described. No extra reductants are needed for Julia reaction since alcohols work as double sources of aldehydes and the hydride. Generally high yields were given for both terminal and highly (E)-selective internal olefins. ...
DOI:
10.1039/c5cc01965f

47. (E)-α,β-unsaturated amides from tertiary amines, olefins and CO via Pd/Cu-catalyzed aerobic oxidative N-dealkylation

Author:
Renyi Shi; Hua Zhang; Lijun Lu; Pei Gan; Yuchen Sha; Heng Zhang; Qiang Liu; Matthias Beller; Aiwen Lei
Source:
Chemical communications 2015 v.51 no.15 pp. 3247-3250
ISSN:
1364-548X
Subject:
alkenes; amides; catalysts; catalytic activity; chemical reactions; chemoselectivity; palladium; secondary amines; tertiary amines
Abstract:
... A novel Pd/Cu-catalyzed chemoselective aerobic oxidative N-dealkylation/carbonylation reaction has been developed. Tertiary amines are utilized as a “reservoir” of “active” secondary amines in this transformation, which inhibits the formation of undesired by-products and the deactivation of the catalysts. This protocol allows for an efficient and straightforward construction of synthetically usefu ...
DOI:
10.1039/c4cc08925a

48. (E)-β-caryophyllene functions as a host location signal for the rice white-backed planthopper Sogatella furcifera

Author:
Qi Wang; Zhaojun Xin; Jiancai Li; Lingfei Hu; Yonggen Lou; Jing Lu
Source:
Physiological and molecular plant pathology 2015 v.91 pp. 106-112
ISSN:
0885-5765
Subject:
Anagrus; Chilo suppressalis; Nilaparvata lugens; Sogatella furcifera; cytoplasm; eggs; herbivores; insect pests; jasmonic acid; mutants; natural enemies; oviposition; parasitoids; rice; terpenoids
Abstract:
... Terpenoids are well known to mediate interactions among plants, herbivores and their natural enemies. In rice, (E)-β-caryophyllene has been reported to attract a major insect pest, Nilaparvata lugens, and its egg parasitoid, Anagrus nilaparvatae. Yet, it remains unclear whether (E)-β-caryophyllene also influences other herbivores in rice. Here we demonstrated that a rice (E)-β-caryophyllene syntha ...
DOI:
10.1016/j.pmpp.2015.07.002

49. (False) Dichotomies, political ideologies, and preferences for environmental management along the rural-urban interface in Calaveras County, California

Author:
Colleen C. Hiner
Source:
Applied geography 2015 v.65 pp. 13-27
ISSN:
0143-6228
Subject:
cultural landscape; environmental management; geography; governance; issues and policy; land use planning; politics; problem solving; public services and goods; society; stakeholders; California
Abstract:
... At the core of land use and governance debates in the United States are purported dualities: economy vs. environment, public goods vs. private rights, and the merits and demerits of regulation. While such dichotomies are inevitably partial, they offer a heuristic to interrogate the deeper nuances of a problem or process. I investigate these dichotomies in one site (Calaveras County, California) al ...
DOI:
10.1016/j.apgeog.2015.10.001

50. (Fe,Co)@nitrogen-doped graphitic carbon nanocubes derived from polydopamine-encapsulated metal–organic frameworks as a highly stable and selective non-precious oxygen reduction electrocatalyst

Author:
Jiangbo Xi; Yating Xia; Yangyang Xu; Junwu Xiao; Shuai Wang
Source:
Chemical communications 2015 v.51 no.52 pp. 10479-10482
ISSN:
1364-548X
Subject:
catalysts; catalytic activity; cobalt; coordination polymers; durability; electrochemistry; graphene; nanomaterials; oxygen; platinum; pyrolysis
Abstract:
... A facile approach is reported to synthesize (Fe,Co)@nitrogen-doped graphitic carbon (NGC) nanocubes (NCs) via the pyrolysis of polydopamine-encapsulated Fe₃[Co(CN)₆]₂ NCs at 700 °C. Besides the comparable catalytic activity for oxygen reduction reaction (ORR) to the Pt/C catalyst, it showed much more outstanding catalytic selectivity and superior durability. ...
DOI:
10.1039/c5cc03946k

51. (GAA)n microsatellite as an indicator of the A genome reorganization during wheat evolution and domestication

Author:
Irina G. Adonina; Nikolay P. Goncharov; Ekaterina D. Badaeva; Ekaterina M. Sergeeva; Nadezhda V. Petrash; Elena A. Salina
Source:
Comparative cytogenetics 2015 v.9 no.4 pp. 533-547
ISSN:
1993-078X
Subject:
Triticum aestivum; Triticum monococcum subsp. aegilopoides; Triticum timopheevii; Triticum turgidum subsp. dicoccoides; Triticum turgidum subsp. dicoccon; Triticum turgidum subsp. durum; Triticum urartu; diploidy; domestication; evolution; genome; microsatellite repeats; nucleolus organizer region; polyploidy; wheat
Abstract:
... Although the wheat A genomes have been intensively studied over past decades, many questions concerning the mechanisms of their divergence and evolution still remain unsolved. In the present study we performed comparative analysis of the A genome chromosomes in diploid (Triticum urartu Tumanian ex Gandilyan, 1972, Triticum boeoticum Boissier, 1874 and Triticum monococcum Linnaeus, 1753) and polypl ...
DOI:
10.3897/CompCytogen.v9i4.5120

52. (Gentianaceae), a New Species from Bolivia

Author:
Pringle James S.
Source:
Novon 2015 v.24 no.2 pp. 182-185
ISSN:
1055-3177
Subject:
Gentianaceae; leaves; new species; Bolivia
Abstract:
... The new species Gentianella zaratei J. S. Pringle (Gentianaceae) is described from the departments of Potosí and Oruro, Bolivia. It has longitudinally striped, scarlet and yellow, scarcely opening corollas like those of G. erythrochrysea (Gilg) Fabris and G. hirculus (Griseb.) Fabris but differs in its ascending, narrowly linear leaves. ...
DOI:
10.3417/2014010

53. (Hyper)tension release by N-terminal acetylation

Author:
Henriette Aksnes; Adrian Drazic; Thomas Arnesen
Source:
Trends in biochemical sciences 2015 v.40 pp. 422-424
ISSN:
0968-0004
Subject:
G-proteins; acetylation; acetyltransferases; blood pressure; mutants
Abstract:
... A recent study links N-terminal acetylation and N-end rule degradation to blood pressure regulation. N-terminal mutants of Rgs2, a key G-protein regulator, are differentially processed by N-terminal acetyltransferases and the two branches of the N-end rule pathway. This leads to an imbalance in the signaling governing blood pressure. ...
DOI:
10.1016/j.tibs.2015.05.003

54. (K,Na)NbO3 Nanofiber-based Self-Powered Sensors for Accurate Detection of Dynamic Strain

Author:
Wang Zhao; Zhang Youdong; Yang Shulin; Hu Yongming; Wang Shengfu; Gu Haoshuang; Wang Yu; Chan H. L. W.; Wang John
Source:
ACS Applied Materials & Interfaces 2015 v.7 no.8 pp. 4921-4927
ISSN:
1944-8252
Subject:
deformation; nanofibers; packaging; polymers; vibration
Abstract:
... A self-powered active strain sensor based on well-aligned (K,Na)NbO₃ piezoelectric nanofibers is successfully fabricated through the electrospinning and polymer packaging process. The device exhibits a fast, active response to dynamic strain by generating impulsive voltage signal that is dependent on the amplitude of the dynamic strains and the vibration frequency. When the frequency is fixed at 1 ...
DOI:
10.1021/am5090012

55. (Lipo)polysaccharide interactions of antimicrobial peptides

Author:
Artur Schmidtchen; Martin Malmsten
Source:
Journal of colloid and interface science 2015 v.449 pp. 136-142
ISSN:
0021-9797
Subject:
antibiotics; antimicrobial peptides; polysaccharides
Abstract:
... Due to rapidly increasing resistance development against conventional antibiotics, as well as problems associated with diseases either triggered or deteriorated by infection, antimicrobial and anti-inflammatory peptides have attracted considerable interest during the last few years. While there is an emerging understanding of the direct antimicrobial function of such peptides through bacterial mem ...
DOI:
10.1016/j.jcis.2014.11.024

56. (NH4) 2SO 4 recovery from liquid side streams

Author:
Marc Anton Boehler; Alexander Heisele; Alexander Seyfried; Markus Grömping; Hansruedi Siegrist
Source:
Environmental science and pollution research international 2015 v.22 no.10 pp. 7295-7305
ISSN:
0944-1344
Subject:
ammonia; ammonium sulfate; carbon dioxide; energy; fouling; heat; hydrophobicity; nitrogen; pH; pretreatment; sludge; streams; sulfuric acid; surface tension; temperature; urine; wastewater; wastewater treatment
Abstract:
... Two methods of recovering nitrogen from liquid side streams are presented in this paper. The first method was demonstrated at an ammonia stripping plant treating 5–7 m³/h sludge water at the wastewater treatment plant (WWTP) Kloten-Opfikon (CH). In addition to the usual stripping and scrubbing columns, a third column had been added in order strip CO₂, thus reducing the NaOH-demand of the subsequen ...
DOI:
10.1007/s11356-014-3392-8

57. (Poly)phenolic characterization of three food supplements containing 36 different fruits, vegetables and berries

Author:
Letizia Bresciani; Luca Calani; Marta Cossu; Pedro Mena; Marietta Sayegh; Sumantra Ray; Daniele Del Rio
Source:
PharmaNutrition 2015 v.3 no.2 pp. 11-19
ISSN:
2213-4344
Subject:
anthocyanins; bioactive compounds; coumaric acids; dietary supplements; flavanols; flavanones; flavonols; food plants; fruits; lignans; plant-based foods; proanthocyanidins; small fruits; vegetables
Abstract:
... There is continuously accruing evidence to suggest the health benefits of consuming fruits and vegetables. Food supplements may represent an effective and acceptable method to deliver a way of providing bioactive compounds to consumers. The aim of this work was to characterize the (poly)phenolic composition of three plant-based food supplements designed to integrate and increase the daily intake o ...
DOI:
10.1016/j.phanu.2015.01.001

58. (Poly)phenolic compounds and antioxidant activity of white (Morus alba) and black (Morus nigra) mulberry leaves: Their potential for new products rich in phytochemicals

Author:
Eva M. Sánchez-Salcedo; Pedro Mena; Cristina García-Viguera; Francisca Hernández; Juan José Martínez
Source:
Journal of functional foods 2015 v.18 pp. 1039-1046
ISSN:
1756-4646
Subject:
Morus alba; Morus nigra; antioxidant activity; antioxidants; chlorogenic acid; clones; flavonols; food matrix; leaves; mulberries; new products; pharmaceutical industry; phenolic compounds; phytopharmaceuticals; principal component analysis; value added; Spain
Abstract:
... The (poly)phenolic fingerprint and antioxidant activities of the leaves of white and black mulberry clones grown in Spain, one of the main European producers, were evaluated for the first time in order to examine their phytochemical potential. Data showed that mulberry leaves are rich in caffeoylquinic acids (6.8–8.5 mg/g dw) and flavonols (3.7–9.8 mg/g dw). It was also evidenced that a wide intra ...
DOI:
10.1016/j.jff.2015.03.053

59. (R)-PAC Biosynthesis in [BMIM][PF6]/Aqueous Biphasic System Using Saccharomyces cerevisiae BY4741 Cells

Author:
Smita Kandar; A. K. Suresh; Santosh B. Noronha
Source:
Applied biochemistry and biotechnology 2015 v.175 no.4 pp. 1771-1788
ISSN:
0273-2289
Subject:
Saccharomyces cerevisiae; benzaldehyde; benzyl alcohol; biocompatibility; biosynthesis; biotechnology; biotransformation; ephedrine; glucose; hydrophobicity; ionic liquids; pseudoephedrine; pyruvate decarboxylase; response surface methodology; toxicity
Abstract:
... (R)-phenylacetylcarbinol or (R)-PAC is a pharmaceutical precursor of (1R, 2S) ephedrine and (1S, 2S) pseudoephedrine. Biotransformation of benzaldehyde and glucose by pyruvate decarboxylase produces (R)-PAC. This biotransformation suffers from toxicity of the substrate, product [(R)-PAC] and by-product (benzyl alcohol). In the present study, ionic liquid/aqueous biphasic system was employed to enh ...
DOI:
10.1007/s12010-014-1394-0

60. (S)-Naproxen based novel chiral reagent for C–N bond formation: enantioseparation of some β-blockers, determination of absolute configuration and elution order of diastereomers

Author:
Manisha Singh; Ravi Bhushan
Source:
RSC advances 2015 v.5 no.86 pp. 70255-70264
ISSN:
2046-2069
Subject:
acetonitrile; ambient temperature; amides; beta-adrenergic antagonists; buffers; chemical bonding; derivatization; detection limit; diammonium phosphate; diastereomers; energy; geometry; guidelines; microwave radiation; naphthaleneacetic acid; reversed-phase high performance liquid chromatography
Abstract:
... A new chiral derivatizing reagent has been synthesized from (S)-(+)-naproxen and was used for C–N bond formation to prepare diastereomeric amides of (RS)-propranolol, (RS)-atenolol, (RS)-carvedilol and (RS)-metoprolol. Derivatization reactions were done at room temperature (30 °C for 30 min) under stirring conditions as well as under microwave irradiation (MWI). Separation of diastereomers was ach ...
DOI:
10.1039/c5ra07519j

61. (Sub)surface-Promoted Disproportionation and Absolute Band Alignment in High-Power LiMn2O4 Cathodes

Author:
Scivetti Ivan; Teobaldi Gilberto
Source:
The Journal of Physical Chemistry C 2015 v.119 no.37 pp. 21358-21368
ISSN:
1932-7455
Subject:
cathodes; cations; electrochemistry; geometry; lithium; lithium batteries; manganese; manganese oxides; methodology; physical chemistry; van der Waals forces
Abstract:
... We present an isotropic (Uₑff) and anisotropic (U–J) Hubbard and van der Waals (vdW)-corrected density functional theory study of bulk and low-index surfaces of lithium manganese oxide LiMn₂O₄ (LMO), a promising cathode material for high-power Li-ion batteries. Use of anisotropic (U–J) corrections in the simulation of bulk LMO leads to improved agreement with available experimental data, whereas v ...
DOI:
10.1021/acs.jpcc.5b06522

62. (TFPP)Eu[Pc(OPh)8]Eu[Pc(OPh)8]/CuPc Two-Component Bilayer Heterojunction-Based Organic Transistors with High Ambipolar Performance

Author:
Gao Dameng; Zhang Xia; Kong Xia; Chen Yanli; Jiang Jianzhuang
Source:
ACS Applied Materials & Interfaces 2015 v.7 no.4 pp. 2486-2493
ISSN:
1944-8252
Subject:
X-ray diffraction; electrons; europium; semiconductors
Abstract:
... Organic thin film transistor (OTFT) devices fabricated by the solution-based QLS technique from a mixed (phthalocyaninato)(porphyrinato) europium complex (TFPP)Eu[Pc(OPh)₈]Eu[Pc(OPh)₈] exhibit air-stable ambipolar performance with mobilities of 6.0 × 10–⁵ cm² V⁻¹ s⁻1 for holes and 1.4 × 10–⁴ cm² V–¹ s–¹ for electrons, respectively. In good contrast, the two-component bilayer heterojunction thin fi ...
DOI:
10.1021/am507353s

63. (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions – a review

Author:
Carlos M. H. Ferreira; Isabel S. S. Pinto; Eduardo V. Soares; Helena M. V. M. Soares
Source:
RSC advances 2015 v.5 no.39 pp. 30989-31003
ISSN:
2046-2069
Subject:
acids; buffers; chemical speciation; metal ions; metals; pH; zwitterions
Abstract:
... The use of buffers to maintain the pH within a desired range is a very common practice in chemical, biochemical and biological studies. Among them, zwitterionic N-substituted aminosulfonic acids, usually known as Good’s buffers, although widely used, can complex metals and interact with biological systems. The present work reviews, discusses and updates the metal complexation characteristics of th ...
DOI:
10.1039/c4ra15453c

64. (Y,Tb,Eu)₂O₃ monospheres for highly fluorescent films and transparent hybrid films with color tunable emission

Author:
Qi Zhu; Mei Xiong; Ji-Guang Li; Weigang Liu; Zhihao Wang; Xiaodong Li; Xudong Sun
Source:
RSC advances 2015 v.5 no.45 pp. 36122-36128
ISSN:
2046-2069
Subject:
color; emissions factor; energy conversion; energy transfer; europium; films (materials); fluorescence; packaging; packaging materials; polymers; terbium; transmittance; ultraviolet radiation
Abstract:
... (Y,Tb,Eu)₂O₃ monospheres (∼180 nm in diameter), calcined from the precursors synthesized via urea-based homogeneous precipitation, were employed as the building blocks for highly fluorescent films and as the dispersion fillers for transparent polymer films. The oxide spheres, consisting of ∼40 nm grains, simultaneously displayed the green emission of Tb³⁺ at 543 nm and the red emission of Eu³⁺ at ...
DOI:
10.1039/c5ra04665c

65. (Z)- or (E)-Selective Hydrogenation of Potassium (3,3,3-Trifluoroprop-1-yn-1-yl)trifluoroborate: Route to Either Isomer of β-Trifluoromethylstyrenes

Author:
Ramachandran P. Veeraraghavan; Mitsuhashi Wataru
Source:
Organic letters 2015 v.17 no.5 pp. 1252-1255
ISSN:
1523-7052
Subject:
catalysts; catalytic activity; hydrogenation; isomers; organic compounds; palladium; potassium
Abstract:
... A Pd-catalyzed hydrogenation of potassium (3,3,3-trifluoroprop-1-yn-1-yl)trifluoroborate providing either the (Z)- or (E)-isomer of the vinylborate in >98% purity is described. The initially formed (Z)-isomer of the alkene is transformed to the (E)-isomer with time, irrespective of the catalyst used; coupling with bromo- and iodoarenes provides a variety of (Z)- or (E)-β-trifluoromethylstyrenes. A ...
DOI:
10.1021/acs.orglett.5b00235

66. (Z)-13-Hexadecenyl Acetate: a Novel Moth Sex Pheromone Component from Herpetogramma submarginale (Lepidoptera: Crambidae)

Author:
Qi Yan; Kento Kuriyama; Keisuke Nishikawa; Satoru Tominaga; Haruki Tatsuta; Tetsu Ando; Hideshi Naka
Source:
Journal of chemical ecology 2015 v.41 no.5 pp. 441-445
ISSN:
0098-0331
Subject:
Herpetogramma; acetates; electroantennography; field experimentation; gas chromatography; males; mass spectrometry; moths; sex pheromones; spectral analysis; virgin females
Abstract:
... The sex pheromone of Herpetogramma submarginale (Swinhoe) was studied by gas chromatography (GC) with electroantennographic detection and GC coupled with mass spectrometry. Two pheromone candidates detected in the gland extracts of females were identified as (Z)-13-hexadecenyl acetate (Z13-16:OAc) and (E)-13-hexadecenyl acetate (E13-16:OAc) in a ratio of 87:13 by mass spectral analysis of the natu ...
DOI:
10.1007/s10886-015-0576-8

67. (Z)-3-Hexenal, One of the Green Leaf Volatiles, Increases Susceptibility of Rice to the White-Backed Planthopper Sogatella furcifera

Author:
Baohui Wang; Guoxin Zhou; Zhaojun Xin; Rui Ji; Yonggen Lou
Source:
Plant molecular biology reporter 2015 v.33 no.3 pp. 377-387
ISSN:
0735-9640
Subject:
Agrobacterium; Oryza sativa; Sogatella furcifera; adults; bioassays; eggs; females; gene expression; gene expression regulation; genes; genetic transformation; homozygosity; insect pests; leaves; males; nymphs; oviposition; oxylipins; pathogens; rice; volatile compounds
Abstract:
... Green leaf volatiles (GLVs), the products of the hydroperoxide lyase (HPL) branch of the oxylipin pathway, play important roles in plant defense responses to both insect pests and pathogens. However, little is known about the role of GLVs in the defense responses of rice to the white-backed planthopper (WBPH, Sogatella furcifera (Horváth)). Here, we found that the rice HPL gene OsHPL3 was upregula ...
DOI:
10.1007/s11105-014-0756-7

68. (Z)-3-hexenyl acetate and 1-undecanol increase male attraction to sex pheromone trap in Grapholita molesta (Busck) (Lepidoptera: Tortricidae)

Author:
Haili Yu; Jianlu Feng; Qingwen Zhang; Huanli Xu
Source:
International journal of pest management 2015 v.61 no.1 pp. 30-35
ISSN:
1366-5863
Subject:
Grapholita molesta; acetates; bait traps; males; moths; pears; pest management; pheromone traps; sex pheromones; synergists
Abstract:
... The effects of host-plant volatiles (HPVs) on male oriental fruit moth, Grapholita molesta (Busck) (Lepidoptera: Tortricidae), and response to sex pheromone trap were studied in a pear orchard. Two HPVs compounds, (Z)-3-hexenyl acetate and 1-undecanol, combined with sex pheromone of G. molesta in traps were tested. The results showed that most of the male moths were captured in the traps baited wi ...
DOI:
10.1080/09670874.2014.986560

69. (Z)-Selective Enol Triflation of α-Alkoxyacetoaldehydes: Application to Synthesis of (Z)-Allylic Alcohols via Cross-Coupling Reaction and [1,2]-Wittig Rearrangement

Author:
Kurosawa Fumiya; Nakano Takeo; Soeta Takahiro; Endo Kohei; Ukaji Yutaka
Source:
Journal of organic chemistry 2015 v.80 no.11 pp. 5696-5703
ISSN:
1520-6904
Subject:
chemical structure; cross-coupling reactions; enols; organic chemistry; stereochemistry; stereoselective synthesis; stereoselectivity
Abstract:
... The stereoselective transformation of α-alkoxyacetoaldehydes to the corresponding (Z)-vinyl triflates was achieved by treatment with phenyl triflimide and DBU. The stereochemistry was explained by the “syn-effect,” which was attributed primarily to an σ → π* interaction. The β-alkoxy vinyl triflates obtained were applied to the stereoselective synthesis of structurally diverse (Z)-allylic alcohols ...
DOI:
10.1021/acs.joc.5b00647

70. (Z)-Stereoselective Synthesis of Mono- and Bis-heterocyclic Benzimidazol-2-ones via Cascade Processes Coupled with the Ugi Multicomponent Reaction

Author:
Xu Zhigang; Martinez-Ariza Guillermo; Cappelli Alexandra P.; Roberts Sue A.; Hulme Christopher
Source:
Journal of organic chemistry 2015 v.80 no.18 pp. 9007-9015
ISSN:
1520-6904
Subject:
X-ray diffraction; acid treatment; chemical structure; organic chemistry; organic compounds; tautomerization
Abstract:
... Several novel cascade reactions are herein reported that enable access to a variety of unique mono- and bis-heterocyclic scaffolds. The sequence of cascade events are mediated through acid treatment of an Ugi adduct that affords 1,5-benzodiazepines which subsequently undergo an elegant rearrangement to deliver (E)-benzimidazolones, which through acid-promoted tautomerization convert to their corre ...
DOI:
10.1021/acs.joc.5b00955

71. (±)-Acortatarinowins A–F, Norlignan, Neolignan, and Lignan Enantiomers from Acorus tatarinowii

Author:
Lu Yuanyuan; Xue Yongbo; Liu Junjun; Yao Guangmin; Li Dongyan; Sun Bin; Zhang Jinwen; Liu Yanfei; Qi Changxing; Xiang Ming; Luo Zengwei; Du Guang; Zhang Yonghui
Source:
Journal of natural products 2015 v.78 no.9 pp. 2205-2214
ISSN:
1520-6025
Subject:
Acorus gramineus; X-ray diffraction; circular dichroism spectroscopy; enantiomers; high performance liquid chromatography; inhibitory concentration 50; lignans; macrophages; nitric oxide; rhizomes
Abstract:
... Three pairs of new 8-O-4′-type dinorneolignan enantiomers, (±)-acortatarinowins A–C (1a/1b–3a/3b), a pair of new 8-O-4′-type (4a/4b) and a pair of rare C7–C8′-type (5a/5b) neolignan enantiomers, (±)-acortatarinowins D and E, and a pair of new furofuran-type lignan enantiomers, (±)-acortatarinowin F (6a/6b), along with two pairs of known lignan enantiomers (7a/7b and 8a/8b), were obtained from the ...
DOI:
10.1021/acs.jnatprod.5b00328

72. (±)-Melicolones A and B, Rearranged Prenylated Acetophenone Stereoisomers with an Unusual 9-Oxatricyclo[3.2.1.13,8]nonane Core from the Leaves of Melicope ptelefolia

Author:
Xu Jin-Fang; Zhao Hui-Jun; Wang Xiao-Bing; Li Zhong-Rui; Luo Jun; Yang Ming-Hua; Yang Lei; Yu Wen-Ying; Yao He-Quan; Luo Jian-Guang; Kong Ling-Yi
Source:
Organic letters 2015 v.17 no.1 pp. 146-149
ISSN:
1523-7052
Subject:
Melicope; chemical reactions; enantiomers; endothelial cells; high performance liquid chromatography; humans; leaves; organic compounds; oxidative stress; spectral analysis
Abstract:
... Melicolones A (1) and B (2), a pair of rearranged prenylated acetophenone epimers with an unusual 9-oxatricyclo[3.2.1.1³,⁸]nonane core, were isolated from the leaves of Melicope ptelefolia. Further chiral high-performance liquid chromatography resolution gave enantiomers (+)- and (−)-1, as well as (+)- and (−)-2, respectively. The structures and absolute configurations of the pure enantiomers were ...
DOI:
10.1021/ol5033738

73. (±)-Quassidines I and J, Two Pairs of Cytotoxic Bis-β-carboline Alkaloid Enantiomers from Picrasma quassioides

Author:
Jiao Wei-Hua; Chen Guo-Dong; Gao Hao; Li Jing; Gu Bin-Bin; Xu Ting-Ting; Yu Hao-Bing; Shi Guo-Hua; Yang Fan; Yao Xin-Sheng; Lin Hou-Wen
Source:
Journal of natural products 2015 v.78 no.1 pp. 125-130
ISSN:
1520-6025
Subject:
Picrasma quassioides; X-ray diffraction; alkaloids; cytotoxicity; enantiomers; high performance liquid chromatography; humans; inhibitory concentration 50; melanoma; mice; nuclear magnetic resonance spectroscopy; spectral analysis; stems
Abstract:
... (±)-Quassidines I (1) and J (2), two pairs of new bis-β-carboline alkaloid enantiomers, were isolated from the stems of Picrasma quassioides. Their structures were determined by the analysis of spectroscopic data, including HRESIMS and 2D NMR, and confirmed by single-crystal X-ray diffraction analysis. The racemic mixtures of 1 and 2 were resolved into two pairs of enantiomers, (+)-S-1a and (−)-R- ...
DOI:
10.1021/np500801s

74. (±)-Salviaprione, a pair of unprecedented abietane-type diterpeniods from Salvia prionitis

Author:
Yong-Jun Jiang; Yu Zhang; Juan He; Xing-De Wu; Li-Dong Shao; Xiao-Nian Li; Jia Su; Li-Yan Peng; Rong-Tao Li; Qin-Shi Zhao
Source:
Tetrahedron letters 2015 v.56 pp. 5457-5459
ISSN:
0040-4039
Subject:
Prionitis; Salvia; X-ray diffraction; biogenesis; chemical reactions; chemical structure; circular dichroism spectroscopy; high performance liquid chromatography; nuclear magnetic resonance spectroscopy; organic compounds
Abstract:
... (+)-Salviaprione and (−)-salviaprione, a pair of unprecedented abietane-type diterpeniods having an unprecedented 5/6/6 tricyclic ring system with a unique five membered ring A formed by a new C-2/C-11 bond, were isolated from the whole plant of Salvia prionitis. The enantiomeric separation was achieved by HPLC on a chiral column. Their structures and absolute configurations were determined on the ...
DOI:
10.1016/j.tetlet.2015.08.022

75. (±)-Sinensilactam A, a Pair of Rare Hybrid Metabolites with Smad3 Phosphorylation Inhibition from Ganoderma sinensis

Author:
Luo Qi; Tian Lei; Di Lei; Yan Yong-Ming; Wei Xiao-Yi; Wang Xin-Fang; Cheng Yong-Xian
Source:
Organic letters 2015 v.17 no.6 pp. 1565-1568
ISSN:
1523-7052
Subject:
Ganoderma; X-ray diffraction; biosynthesis; chemical structure; fruiting bodies; humans; metabolites; organic compounds; phosphorylation; spectroscopy; transforming growth factor beta 1
Abstract:
... (+)- and (−)-Sinensilactam A (1), novel hybrid metabolites possessing a unique 2H-pyrrolo[2,1-b][1,3]oxazin-6(7H)-one ring system, were isolated from the fruit bodies of Ganoderma sinensis. The structures of these substances and absolute configurations at their stereocenters were assigned using spectroscopic and computational methods along with X-ray crystallographic analysis. A plausible pathway ...
DOI:
10.1021/acs.orglett.5b00448

76. (−)-Epigallocatechin-3-gallate Inhibits Fibrillogenesis of Chicken Cystatin

Author:
Na Wang; Jianwei He; Alan K. Chang; Yu Wang; Linan Xu; Xiaoying Chong; Xian Lu; Yonghui Sun; Xichun Xia; Hui Li; Bing Zhang; Youtao Song; Akio Kato; Gary W. Jones
Source:
Journal of agricultural and food chemistry 2015 v.63 no.5 pp. 1347-1351
ISSN:
0021-8561
Subject:
amyloid; chickens; flavonoids; green tea; mutants; polypeptides
Abstract:
... Previous studies have reported that (−)-epigallocatechin-3-gallate (EGCG), the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. To elucidate whether this antifibril activity is specific to disease-related target proteins or is more generic, we investigated the ability of EGCG to inhibit amyloid fibril formation of amyloidog ...
DOI:
10.1021/jf505277e

77. (−) and (+)-Merrilliaquinone, a pair of new quinone enantiomers from Illicium merrillianum and their distinctive effect on human hepatoma and hepatic cells

Author:
Xinhui Tian; Li Li; Jinpeng Pei; Rongcai Yue; Xin Fang; Jianping Zhang; Weiwei He; Lei Shan; Yunheng Shen; Weidong Zhang
Source:
RSC advances 2015 v.5 no.93 pp. 75857-75862
ISSN:
2046-2069
Subject:
Illicium; apoptosis; cell cycle checkpoints; cytotoxicity; enantiomers; flow cytometry; hepatoma; inhibitory concentration 50; interphase; membrane potential; mitochondrial membrane; quantum mechanics; quinones; spectral analysis
Abstract:
... Merrilliaquinone (1), a new racemic quinone was isolated from the branches and leaves of Illicium merrillianum. Chiral separation of 1 gave two enantiomers (−)-merrilliaquinone (1a) and (+)-merrilliaquinone (1b). The structure of 1 was established by comprehensive spectroscopic analysis, and the absolute configurations of 1a and 1b were determined by quantum mechanical calculation of ECD spectra. ...
DOI:
10.1039/c5ra15074d

78. (−)-Epicatechin reduces blood pressure increase in high-fructose-fed rats: effects on the determinants of nitric oxide bioavailability

Author:
Maria C. Litterio; Marcela A. Vazquez Prieto; Ana M. Adamo; Rosana Elesgaray; Patricia I. Oteiza; Monica Galleano; Cesar G. Fraga
Source:
Journal of nutritional biochemistry 2015 v.26 pp. 745-751
ISSN:
0955-2863
Subject:
NAD(P)H oxidase (H2O2-forming); aorta; bioavailability; blood pressure; body weight; diet; drinking water; endothelial nitric oxide synthase; epicatechin; fructose; hypertension; metabolic syndrome; mitogen-activated protein kinase; models; nitric oxide; phosphorylation; rats; superoxide anion
Abstract:
... This work investigated the blood pressure (BP)-lowering effect of the flavanol (−)-epicatechin in a model of metabolic syndrome. Rats were fed a regular chow diet without (Control) or with 10% (w/v) fructose in the drinking water (high fructose, HF) for 8 weeks. A subgroup of the HF-fed rats was supplemented with (−)-epicatechin 20 mg/kg body weight (HF-EC). Dietary (−)-epicatechin reverted the in ...
DOI:
10.1016/j.jnutbio.2015.02.004

79. (−)-Epicatechin-3-gallate (a polyphenol from green tea) potentiates doxorubicin-induced apoptosis in H9C2 cardiomyocytes

Author:
Yi Cai; Hui-Qi Hong; Li Zhao; Yue-Peng Cai; Yuan Qin
Source:
Biotechnology letters 2015 v.37 no.10 pp. 1937-1943
ISSN:
0141-5492
Subject:
AMP-activated protein kinase; apoptosis; cardiomyocytes; cytotoxicity; dose response; doxorubicin; green tea; phosphorylation; polyphenols; proteins
Abstract:
... OBJECTIVE: The effect of epicatechin-3-gallate (ECG), a polyphenol that is present in green tea, on doxorubicin (DOX) cytotoxicity in H9C2 cardiomyocytes and its underlying mechanisms were investigated. RESULTS: Pretreatment with ECG (20 and 30 μM) significantly increased DOX-induced apoptosis to 16–18 % in H9C2 cardiomyocytes. The Bax/Bcl-2 ratio increased significantly after 1 h pretreatment wit ...
DOI:
10.1007/s10529-015-1879-0

80. (−)-Epigallocatechin-3-gallate inhibits matrix metalloproteinases in oral ulcers

Author:
Bin Huang; Huangqin Chen
Source:
RSC advances 2015 v.5 no.30 pp. 23758-23766
ISSN:
2046-2069
Subject:
Western blotting; acetic acid; animal models; colorimetry; dose response; enzyme-linked immunosorbent assay; epigallocatechin gallate; extracellular matrix; fluorometry; immunohistochemistry; interleukin-1beta; luciferase; macrophages; metalloproteinases; quantitative polymerase chain reaction; transcription (genetics)
Abstract:
... The overexpression of matrix metalloproteinases (MMPs) results in excessive extracellular matrix degradation and oral ulcer healing delay. This study investigated the inhibitory effect of (−)-epigallocatechin-3-gallate (EGCG) on MMPs, the possible molecular mechanism and its implications for oral ulcers. MMP-1 and MMP-9 inhibition was detected using fluorometric and colorimetric assays after incub ...
DOI:
10.1039/c5ra01263e

81. (−)-α-Bisabolol, a Promising Oral Compound for the Treatment of Visceral Leishmaniasis

Author:
Corpas-López Victoriano; Morillas-Márquez Francisco; Navarro-Moll M. Concepción; Merino-Espinosa Gemma; Díaz-Sáez Victoriano; Martín-Sánchez Joaquina
Source:
Journal of natural products 2015 v.78 no.6 pp. 1202-1207
ISSN:
1520-6025
Subject:
Leishmania infantum; amastigotes; animal models; cytotoxicity; drugs; etiological agents; inhibitory concentration 50; liver; macrophages; mice; parasite load; promastigotes; spleen; visceral leishmaniasis
Abstract:
... The aim of the present study was to assess the in vitro and in vivo activity of (−)-α-bisabolol (1) against the etiological agents of visceral leishmaniasis. Bone-marrow-derived macrophages were infected with Leishmania infantum or L. donovani promastigotes and incubated with (−)-α-bisabolol at different concentrations. Pentamidine isethionate and meglumine antimoniate were used as reference drugs ...
DOI:
10.1021/np5008697

82. 1 July 1858 and the 1844 essay: what Lyell and Hooker decided; and what Darwin did not want and did not know

Author:
Derek Partridge
Source:
Biological journal of the Linnean Society 2015 v.116 no.1 pp. 247-251
ISSN:
0024-4066
Subject:
evolution; publications; research
Abstract:
... Two ‘papers’ of Darwin's were read at the famous 1 July 1858 meeting of the Linnean Society: an excerpt from his 1844 essay and a summary of his theory, enclosed in an 1857 letter to Asa Gray. Quite apart from not selecting the essay excerpt, Darwin's letters appear to indicate that he definitely did not want, and hence did not expect, an excerpt from his 1844 essay to be included (and that he did ...
DOI:
10.1111/bij.12561

83. 1, 25(OH)2D3 protects β cell against high glucose-induced apoptosis through mTOR suppressing

Author:
Zesong Yang; Fang Liu; Hua Qu; Hang Wang; Xiaoqiu Xiao; Huacong Deng
Source:
Molecular and Cellular Endocrinology 2015 v.414 pp. 111-119
ISSN:
0303-7207
Subject:
Western blotting; apoptosis; caspases; cytochrome c; death; diabetes mellitus; flow cytometry; gene expression regulation; glucose; islets of Langerhans; mammals; pathogenesis; patients; public health; reverse transcriptase polymerase chain reaction; risk factors; signal transduction; therapeutics; vitamin D deficiency; China
Abstract:
... Diabetes mellitus is a leading cause of death and disability worldwide, which presents a serious public health crisis in China nowadays. It has been well recognized that excessive β-cell apoptosis is the key pathogenesis of diabetes, of which the mammalian target of rapamycin (mTOR) serves as the critical signaling pathway. Emerging evidence indicates that vitamin D deficiency acts as a potential ...
DOI:
10.1016/j.mce.2015.07.023

84. 1,1-Carboboration Reactions of Strongly Electrophilic 2-Borylethyl Thioethers

Author:
Christina Eller; Bastian Billmann; Constantin G. Daniliuc; Gerald Kehr; Gerhard Erker
Source:
Zeitschrift für Naturforschung 2015 v.69 no.11-12 pp. 1357-1364
ISSN:
0932-0776
Subject:
Lewis acids; X-ray diffraction; acetylene; boranes; carbon
Abstract:
... The RSCH₂CH₂B(C₆F₅)₂ boranes 3a (R=Ph) and 3b (R=Et) were in situ generated by HB(C₆F₅)₂ hydroboration of the respective vinylthioethers. Their treatment with R¹-C≡C- SiMe₃ acetylenes resulted in clean 1,1-carboboration to give the respective RSCH₂CH₂-substituted alkenylboranes 4 (3 examples). Likewise, the reagents 3 underwent 1,1-carboboration with the acetylenes Ar₂P-C≡C-SiMe₃ to give the tetra ...
DOI:
10.5560/znb.2014-4190

85. 1,1-Diamino-2,2-dinitroethene (FOX-7) and 1-amino-1-hydrazino-2,2-dinitroethene (HFOX) as amphotères: bases with strong acids

Author:
Thao T. Vo; Jean'ne M. Shreeve
Source:
Journal of materials chemistry A 2015 v.3 no.16 pp. 8756-8763
ISSN:
2050-7496
Subject:
X-ray diffraction; acetone; acids; anions; cations; chemistry; chlorides; hydrazine; hydrazones; oxygen; perchlorates; trinitrotoluene
Abstract:
... The exciting discovery of the first cations based on 1,1-diamino-2,2-dinitroethene (FOX-7) and its hydrazine derivative, 1-amino-1-hydrazino-2,2-dinitroethene (HFOX), along with their syntheses and full characterization is described. The oxygen rich content of these cations lends to their potential as promising precursors for energetic salts. A variety of acids including triflic, perchloric, and h ...
DOI:
10.1039/c4ta07098d

86. 1,1-Dioxothiomorpholines with asymmetric environments: protecting group directed diastereoselectivity of glyco divinyl sulfone cyclization

Author:
Atanu Bhaumik; Tarun Kumar Pal; Tanmaya Pathak
Source:
RSC advances 2015 v.5 no.35 pp. 27706-27710
ISSN:
2046-2069
Subject:
chemical derivatives; cyclization reactions; diastereoselectivity; primary amines; secondary amines
Abstract:
... Divinyl sulfones derived from pyranoside skeletons afforded 1,1-dioxothiomorpholine with predefined asymmetric environments. Although the exocyclic vinyl sulfone group easily reacts with primary amines, the intramolecular addition pattern of the secondary amine leading to the formation of the 1,1-dioxothiomorpholine derivative dramatically varied when benzylidene protection was replaced by benzyl ...
DOI:
10.1039/c5ra03276h

87. 1,19-seco-Avermectin Analogues from a ΔaveCDE Mutant Streptomyces avermectinius Strain

Author:
Sun Peng; Zhao Qunfei; Wu Zhuhua; Zhang Wen; Liu Wen
Source:
Journal of natural products 2015 v.78 no.2 pp. 301-305
ISSN:
1520-6025
Subject:
Streptomyces avermectinius; cytotoxicity; in vitro studies; mutants; spectral analysis
Abstract:
... Three new 1,19-seco-avermectin (AVE) analogues were isolated from the ΔaveCDE mutant Streptomyces avermectinius strain. Their structures were elucidated by detailed spectroscopic analysis. This is the first report of 1,19-seco-AVE analogues. In an in vitro assay these compounds displayed cytotoxicity against Saos-2, MG-63, and B16 cell lines. ...
DOI:
10.1021/np500468f

88. 1,1′-Dihydroxy-2,2′-biimidazoles: a new synthesis and crystal structure

Author:
Alexsei Ya. Tikhonov; Boris A. Selivanov; Yurii V. Gatilov
Source:
Tetrahedron letters 2015 v.56 no.1 pp. 159-161
ISSN:
0040-4039
Subject:
chemical reactions; crystal structure; organic compounds
Abstract:
... An efficient method for the preparation of 1,1′-dihydroxy-2,2′-biimidazoles via cyclization of α,α′-dinitrones is reported. According to the X-ray crystal structure of the product, one ring adopts the 1-hydroxy form and the other ring exists in the N-oxide form. ...
DOI:
10.1016/j.tetlet.2014.11.056

89. 1,2,3-Triazoles derived from olanzapine: their synthesis via an ultrasound assisted CuAAC method and evaluation as inhibitors of PDE4B

Author:
Suresh Babu Nallapati; B. Yogi Sreenivas; Ramudu Bankala; Kishore V. L. Parsa; Shivashankar Sripelly; K. Mukkanti; Manojit Pal
Source:
RSC advances 2015 v.5 no.115 pp. 94623-94628
ISSN:
2046-2069
Subject:
ambient temperature; antipsychotics; inhibitory concentration 50; moieties; triazoles; ultrasonic treatment; ultrasonics
Abstract:
... The antipsychotic drug olanzapine which does not inhibit PDE4 can be converted into the inhibitor of PDE4B via linking its N-10 position with an appropriately N-substituted 1,2,3-triazole moiety through a methylene linker. All these compounds were conveniently prepared by a CuAAC method under ultrasound irradiation at room temperature and evaluated for their PDE4 inhibitory potential in vitro. Thr ...
DOI:
10.1039/c5ra20380e

90. 1,2,4-Triazines Are Versatile Bioorthogonal Reagents

Author:
Kamber David N.; Liang Yong; Blizzard Robert J.; Liu Fang; Mehl Ryan A.; Houk K. N.; Prescher Jennifer A.
Source:
Journal of the American Chemical Society 2015 v.137 no.26 pp. 8388-8391
ISSN:
1520-5126
Subject:
cycloaddition reactions; recombinant proteins; triazines
Abstract:
... A new class of bioorthogonal reagents, 1,2,4-triazines, is described. These scaffolds are stable in biological media and capable of robust reactivity with trans-cyclooctene (TCO). The enhanced stability of the triazine scaffold enabled its direct use in recombinant protein production. The triazine–TCO reaction can also be used in tandem with other bioorthogonal cycloaddition reactions. These featu ...
DOI:
10.1021/jacs.5b05100

91. 1,2,4-Trimethylbenzene disproportionation over large-pore zeolites: An experimental and theoretical study

Author:
Seung Hyeok Cha; Youngchul Byun; Hyung-Ki Min; Suk Bong Hong
Source:
Journal of catalysis 2015 v.323 pp. 145-157
ISSN:
0021-9517
Subject:
catalytic activity; gas chromatography-mass spectrometry; isomers; xylene; zeolites
Abstract:
... While 1,2,4-trimethylbenzene (TMB) disproportionation is one of the potential technologies for p-xylene production, its reaction intermediates have been neither experimentally observed nor identified yet. Here we present GC–MS evidence that not only pentamethylated diphenylmethane (5mDPM) derivatives but also hexamethylated diphenylmethane (6mDPM) ones are serving as key reaction intermediates of ...
DOI:
10.1016/j.jcat.2014.12.029

92. 1,2-Diphosphonium Dication: A Strong P-Based Lewis Acid in Frustrated Lewis Pair (FLP)-Activations of B–H, Si–H, C–H, and H–H Bonds

Author:
Holthausen Michael H.; Bayne Julia M.; Mallov Ian; Dobrovetsky Roman; Stephan Douglas W.
Source:
Journal of the American Chemical Society 2015 v.137 no.23 pp. 7298-7301
ISSN:
1520-5126
Subject:
Lewis acids; chemical bonding; hydrogen; phosphine
Abstract:
... A highly Lewis acidic diphosphonium dication [(C₁₀H₆)(Ph₂P)₂]²⁺ (1), in combination with a Lewis basic phosphine, acts as a purely phosphorus-based frustrated Lewis pair (FLP) and abstracts hydride from [HB(C₆F₅)₃]⁻ and Et₃SiH demonstrating the remarkable hydridophilicity of 1. The P-based FLP is also shown to activate H₂ and C–H bonds. ...
DOI:
10.1021/jacs.5b04109

93. 1,2-Halosilane vs. 1,2-alkylborane elimination from (boryl)(silyl) complexes of iron: switching between borylenes and silylenes just by changing the alkyl group

Author:
Holger Braunschweig; Rian D. Dewhurst; Krzysztof Radacki; Benedikt Wennemann; Qing Ye
Source:
Chemical communications 2015 v.51 no.84 pp. 15465-15468
ISSN:
1364-548X
Subject:
aromatic compounds; boranes; chemical reactions; iron; moieties
Abstract:
... Reaction of different combinations of aryl(dihalo)boranes and trialkylsilyl iron metallates, a route previously used to prepare a terminal iron arylborylene complex, is found to lead to three distinct new reaction outcomes, including unselective decomposition, an inert iron(ii) (boryl)(silyl) complex, and a dinuclear bis(μ-silylene) complex. The latter result is to our knowledge the first example ...
DOI:
10.1039/c5cc06425b

94. 1,2-Hydroboration and 1,1-Carboboration of Alkynyl(ferrocenyl)vinylsilanes. Novel Siloles

Author:
Bernd Wrackmeyer; Elena V. Klimkina; Wolfgang Milius; Christian Butterhof; Kathrin Inzenhofer
Source:
Zeitschrift für Naturforschung 2015 v.69 no.11-12 pp. 1269-1289
ISSN:
0932-0776
Subject:
boron; carbon; moieties; nuclear magnetic resonance spectroscopy; regioselectivity; stable isotopes
Abstract:
... Alkynyl(ferrocenyl)vinylsilanes containing up to three alkynyl units were prepared and treated with 9-borabicyclo[3.3.1]nonane (9-BBN). All reactions proceeded in the beginning by regioselective 1,2-hydroboration of the vinyl group, with boron attached to the terminal carbon. This was followed by intra-molecular 1,1-carboboration, leading to fused silacarbacycles, depending on the number of C≡C bo ...
DOI:
10.5560/znb.2014-4099

95. 1,2-Naphthoquinone-4-sulfonic acid sodium salt as a reagent for spectrophotometric determination of rimantadine and memantine

Author:
I. Muszalska; A. Sobczak; I. Kiaszewicz; K. Rabiega; M. A. Lesniewska; A. Jelińska
Source:
Journal of analytical chemistry 2015 v.70 no.3 pp. 320-327
ISSN:
1061-9348
Subject:
derivatization; methylene chloride; pH; potassium chloride; sodium hydroxide; spectrophotometers
Abstract:
... A selective ultraviolet and visible spectrophotometric method (UV-Vis) for the determination of memantine (MM) and rimantadine (RM) hydrochlorides after derivatization with 1,2-naphtoquinone-4-sulfonic acid sodium salt (NQS) and extraction with dichloromethane was developed and optimized. The reaction of the NQS (0.7%, w/v solution) with memantine was carried out for 40 min in a buffer medium of N ...
DOI:
10.1134/S1061934815030120

96. 1,25(OH)2D3 attenuates TGF-β1/β2-induced increased migration and invasion via inhibiting epithelial–mesenchymal transition in colon cancer cells

Author:
Shanwen Chen; Jing Zhu; Shuai Zuo; Ju Ma; Junling Zhang; Guowei Chen; Xin Wang; Yisheng Pan; Yucun Liu; Pengyuan Wang
Source:
Biochemical and biophysical research communications 2015 v.468 pp. 130-135
ISSN:
0006-291X
Subject:
actin; cadherins; calcitriol; colorectal neoplasms; neoplasm cells; secretion; transcription factors
Abstract:
... 1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) has been reported to inhibit proliferation and migration of multiple types of cancer cells. However, the mechanism underlying its anti-metastasis effect is not fully illustrated. In this study, the effect of 1,25(OH)2D3 on TGF-β1/β2-induced epithelial–mesenchymal transition (EMT) is tested in colon cancer cells. The results suggest that 1,25(OH)2D3 inhibited ...
DOI:
10.1016/j.bbrc.2015.10.146

97. 1,25-(OH)2-vitamin D3 prevents activation of hepatic stellate cells in vitro and ameliorates inflammatory liver damage but not fibrosis in the Abcb4−/− model

Author:
Florian P. Reiter; Simon Hohenester; Jutta M. Nagel; Ralf Wimmer; Renate Artmann; Lena Wottke; Marie-Christine Makeschin; Doris Mayr; Christian Rust; Michael Trauner; Gerald U. Denk
Source:
Biochemical and biophysical research communications 2015 v.459 no.2 pp. 227-233
ISSN:
0006-291X
Subject:
ABC transporters; actin; alanine transaminase; blood serum; calcitriol; cholecalciferol; disease course; fibrosis; hydroxyproline; immunoblotting; immunohistochemistry; immunomodulation; inflammation; liver; matrix metalloproteinase 13; mechanism of action; mice; models; muscles; necrosis; patients; staining
Abstract:
... Vitamin D3-deficiency is common in patients with chronic liver-disease and may promote disease progression. Vitamin D3-administration has thus been proposed as a therapeutic approach. Vitamin D3 has immunomodulatory effects and may modulate autoimmune liver-disease such as primary sclerosing cholangitis. Although various mechanisms of action have been proposed, experimental evidence is limited.Her ...
DOI:
10.1016/j.bbrc.2015.02.074

98. 1,25-Dihydroxyvitamin D3 and extracellular calcium promote mineral deposition via NPP1 activity in a mature osteoblast cell line MLO-A5

Author:
Dongqing Yang; Andrew G. Turner; Asiri R. Wijenayaka; Paul H. Anderson; Howard A. Morris; Gerald J. Atkins
Source:
Molecular and Cellular Endocrinology 2015 v.412 pp. 140-147
ISSN:
0303-7207
Subject:
alkaline phosphatase; calcitriol; calcium; gene expression; messenger RNA; mineralization; osteoblasts; phosphates; small interfering RNA
Abstract:
... While vitamin D supplementation is common, the anabolic mechanisms that improve bone status are poorly understood. Under standard mineralising conditions including media ionised calcium of 1.1 mM, 1,25-dihydroxyvitamin D3 (1,25D) enhanced differentiation and mineral deposition by the mature osteoblast/pre-osteocyte cell line, MLO-A5. This effect was markedly increased with a higher ionised calcium ...
DOI:
10.1016/j.mce.2015.06.005

99. 1,25-Dihydroxyvitamin D3 preserves intestinal epithelial barrier function from TNF-α induced injury via suppression of NF-kB p65 mediated MLCK-P-MLC signaling pathway

Author:
Shanwen Chen; Jing Zhu; Guowei Chen; Shuai Zuo; Junling Zhang; Ziyi Chen; Xin Wang; Junxia Li; Yucun Liu; Pengyuan Wang
Source:
Biochemical and biophysical research communications 2015 v.460 pp. 873-878
ISSN:
0006-291X
Subject:
calcitriol; electrical resistance; epithelium; fluorescent antibody technique; human cell lines; immunoblotting; myosin light chains; occludins; phosphorylation; protective effect; signal transduction; tight junctions; transcription factor NF-kappa B; tumor necrosis factor-alpha
Abstract:
... Substantial studies have demonstrated the protective effect of 1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) on intestinal barrier function, but the mechanisms are not fully illustrated. In this study, the effect of 1,25(OH)2D3 on TNF-α induced barrier dysfunction was further investigated in Caco-2 cell monolayers. The barrier function of Caco-2 monolayers was evaluated by measuring trans-epithelial elec ...
DOI:
10.1016/j.bbrc.2015.03.125

100. 1,25-Dihydroxyvitamin D3/vitamin D receptor suppresses brown adipocyte differentiation and mitochondrial respiration

Author:
Carolyn J. Ricciardi; Jiyoung Bae; Debora Esposito; Slavko Komarnytsky; Pan Hu; Jiangang Chen; Ling Zhao
Source:
European journal of nutrition 2015 v.54 no.6 pp. 1001-1012
ISSN:
1436-6207
Subject:
adenosine triphosphate; adipocytes; adults; animal models; brown adipose tissue; energy expenditure; enzymes; gene overexpression; heat production; humans; knockout mutants; messenger RNA; mice; obesity; oxygen consumption; transcriptional activation; vitamin D
Abstract:
... PURPOSE: The vitamin D system plays a role in metabolism regulation. 1,25-dihydroxyvitamin D₃ (1,25(OH)₂D₃) suppressed 3T3-L1 white adipocyte differentiation. Vitamin D receptor (VDR) knockout mice showed increased energy expenditure, whereas mice with adipose-specific VDR over-expression showed decreased energy expenditure. Brown adipose tissue (BAT), now known to be present in adult humans, func ...
DOI:
10.1007/s00394-014-0778-9