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- Choi, Jeong-Hyeon, et al. Show all 18 Authors
- Journal of genetics and genomics 2015 v.42 no.7 pp. 355-371
- DNA methylation; adults; brain; cell movement; cytotoxicity; epigenetics; gene expression; gene expression regulation; neoplasm cells; neoplasms; pathogenesis; prognosis; stem cells; therapeutics; tumor suppressor genes
- ... Glioblastoma (GBM) is the most common and most aggressive primary brain tumor in adults. The existence of a small population of stem-like tumor cells that efficiently propagate tumors and resist cytotoxic therapy is one proposed mechanism leading to the resilient behavior of tumor cells and poor prognosis. In this study, we performed an in-depth analysis of the DNA methylation landscape in GBM-der ...
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