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- Le Roch, Karine G., et al. Show all 2 Author
- Genome biology 2015 v.16 no.1 pp. 221
- Plasmodium falciparum; RNA-binding proteins; malaria; parasites
- ... During the asexual replication cycle of the malaria parasite Plasmodium falciparum, the RNA-binding protein PfAlba1 binds and stabilizes a subset of transcripts for translation at a later time point.Please see related Research article: http://www.genomebiology.com/2015/16/1/212 ...
- Le Roch, Karine G., et al. Show all 4 Authors
- Tetrahedron 2015 v.71 pp. 487-494
- Plasmodium falciparum; antimalarials; aquatic organisms; beta-lactams; chemical reactions; chemical structure; coasts; diterpenoids; fractionation; humans; malaria; parasites; spectroscopy; Caribbean; Puerto Rico
- ... Bioassay-guided fractionation of the Caribbean sponge Svenzea flava collected near Mona Island, off the west coast of Puerto Rico, led to the isolation of two isocyanide amphilectane-type diterpenes named monamphilectines B and C (2 and 3). Attached to the backbone of each of these compounds is the first α-substituted monocyclic β-lactam ring to be isolated from a marine organism. The molecular st ...
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- Le Roch, Karine G., et al. Show all 6 Authors
- BioEssays 2015 v.37 no.2 pp. 182-194
- Plasmodium falciparum; epigenetics; erythrocytes; genes; histones; humans; models; nucleosomes; parasites
- ... Plasmodium falciparum is the most deadly human malarial parasite, responsible for an estimated 207 million cases of disease and 627,000 deaths in 2012. Recent studies reveal that the parasite actively regulates a large fraction of its genes throughout its replicative cycle inside human red blood cells and that epigenetics plays an important role in this precise gene regulation. Here, we discuss re ...
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