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1. 3D hybrid-domain full waveform inversion on GPU

Author:
Liu, Hongwei,   et al.   ; Liu, Lu; Ding, Renwei; Liu, Hong;     Show all 4 Authors
Source:
Computers & geosciences 2015 v.83 pp. 27-36
ISSN:
0098-3004
Subject:
absorption; algorithms; computer analysis; computers; models
Abstract:
... The traditional frequency-domain full waveform inversion (FWI) method has limited application for 3D case due to its significant computational challenges and huge memory cost. The time-frequency hybrid-domain FWI is thus utilized to combine the computational efficiency of time-domain FWI and multi-scale inversion of frequency-domain FWI. We present a simplified hybrid-domain FWI method. Compared w ...
DOI:
10.1016/j.cageo.2015.06.017

2. Eight new alkaloids with PTP1B and α-glucosidase inhibitory activities from the medicinal mushroom Hericium erinaceus

Author:
Liu, Hongwei,   et al.   ; Wang, Kai; Bao, Li; Ma, Ke; Liu, Ning; Huang, Ying; Ren, Jinwei; Wang, Wenzhao;     Show all 8 Authors
Source:
Tetrahedron 2015 v.71 pp. 9557-9563
ISSN:
0040-4020
Subject:
Hericium; alkaloids; alpha-glucosidase; chemical reactions; chemical structure; circular dichroism spectroscopy; cytotoxicity; doxorubicin; inhibitory concentration 50; medicinal fungi; metabolites; tyrosine
Abstract:
... Eight new alkaloids (1–8), were isolated from the solid culture of Hericium erinaceus. The structures of new metabolites were established by spectroscopic methods. The absolute configuration of 1 was determined by electronic circular dichroism (ECD) calculation. Compounds 5–8 showed inhibitory activities against both protein tyrosine phosphatase-1B (PTP1B) and α-glucosidase. In the cytotoxicity as ...
DOI:
10.1016/j.tet.2015.10.068

3. Investigating Cellular Responses During Photohydrogen Production by the Marine Microalga Tetraselmis subcordiformis by Quantitative Proteome Analysis

Author:
Liu, Hongwei,   et al.   ; Ji, Chaofan; Cao, Xupeng; Qu, Junge; Yao, Changhong; Zou, Hanfa; Xue, Song;     Show all 7 Authors
Source:
Applied biochemistry and biotechnology 2015 v.177 no.3 pp. 649-661
ISSN:
0273-2289
Subject:
NAD (coenzyme); NADH dehydrogenase; Tetraselmis; cyanides; electrons; homeostasis; hydrogen; hydrogen production; metabolites; microalgae; photosystem II; proteins; proteome; proteomics; stress response; tandem mass spectrometry
Abstract:
... The marine microalga Tetraselmis subcordiformis could photoproduce hydrogen under the regulation of carbonyl cyanide m-chlorophenylhydrazone (CCCP), and a hydrogen production process kinetic analysis was characterized by two peaks, suggesting that two distinct mechanisms might exist in this alga. Therefore, 2D nanoliquid chromatography−tandem mass spectrometry (LC-MS/MS) was introduced to analyze ...
DOI:
10.1007/s12010-015-1769-x

4. A novel hydraulic-mechanical hybrid transmission in tidal current turbines

Author:
Liu, Hongwei,   et al.   ; Lin, Yonggang; Shi, Maoshun; Li, Wei; Gu, Haigang; Xu, Quankun; Tu, Le;     Show all 7 Authors
Source:
Renewable energy 2015 v.81 pp. 31-42
ISSN:
0960-1481
Subject:
electricity; energy; renewable energy sources; tides; transmission systems; turbines
Abstract:
... Tidal current energy is a promising renewable energy, and it has become a research hotspot all over the world. Tidal current turbines (TCTs) are the devices that capture tidal current energy and convert it into electricity. Power train is one of the key technologies, and a gearbox is traditionally used. Because of the disadvantages of the gearbox, several soft power transmission methods have been ...
DOI:
10.1016/j.renene.2015.02.059

5. Lanostane Triterpenes from the Tibetan Medicinal Mushroom Ganoderma leucocontextum and Their Inhibitory Effects on HMG-CoA Reductase and α-Glucosidase

Author:
Liu, Hongwei,   et al.   ; Wang, Kai; Bao, Li; Xiong, Weiping; Ma, Ke; Han, Junjie; Wang, Wenzhao; Yin, Wenbing;     Show all 8 Authors
Source:
Journal of natural products 2015 v.78 no.8 pp. 1977-1989
ISSN:
1520-6025
Subject:
Ganoderma lucidum; alpha-glucosidase; cytotoxicity; fruiting bodies; hydroxymethylglutaryl-CoA reductases; inhibitory concentration 50; medicinal fungi; paclitaxel; secondary metabolites; spectral analysis; triterpenoids; yeasts
Abstract:
... Sixteen new lanostane triterpenes, ganoleucoins A–P (1–16), together with 10 known tripterpenes (17–26), were isolated from the cultivated fruiting bodies of Ganoderma leucocontextum, a new member of the Ganoderma lucidum complex. The structures of the new compounds were elucidated by extensive spectroscopic analysis and chemical transformation. The inhibitory effects of 1–26 on HMG-CoA reductase ...
DOI:
10.1021/acs.jnatprod.5b00331

6. Six new 3,4-seco-27-norlanostane triterpenes from the medicinal mushroom Ganoderma boninense and their antiplasmodial activity and agonistic activity to LXRβ

Author:
Liu, Hongwei,   et al.   ; Ma, Ke; Li, Li; Bao, Li; He, Luwei; Sun, Chen; Zhou, Bing; Si, Shuyi;     Show all 8 Authors
Source:
Tetrahedron 2015 v.71 pp. 1808-1814
ISSN:
0040-4020
Subject:
Ganoderma boninense; antimalarials; bioassays; chemical reactions; chemical structure; fruiting bodies; inhibitory concentration 50; median effective concentration; medicinal fungi; spectral analysis; spectroscopy; transcriptional activation; triterpenoids
Abstract:
... Six new 3,4-seco-27-norlanostane triterpenes, ganoboninones A–F (1–6), as well as three known compounds ganoboninketals A–C (7–9), were isolated from the fruiting bodies of the medicinal mushroom Ganoderma boninense. The structures of 1–6 were established by extensive spectroscopic analysis. Compounds 1–6 are new 3,4-seco-27-norlanostane triterpenoids featuring with an interesting tetradecahydrobe ...
DOI:
10.1016/j.tet.2015.02.002

7. Levels of feline infectious peritonitis virus in blood, effusions, and various tissues and the role of lymphopenia in disease outcome following experimental infection

Author:
Liu, Hongwei,   et al.   ; Pedersen, Niels C.; Eckstrand, Chrissy; Leutenegger, Christian; Murphy, Brian;     Show all 5 Authors
Source:
Veterinary microbiology 2015 v.175 no.2-4 pp. 157-166
ISSN:
0378-1135
Subject:
Feline coronavirus; RNA; antibodies; blood serum; cats; feces; fluorescent antibody technique; immunohistochemistry; kidneys; lymph nodes; lymphocyte count; lymphocytes; macrophages; myocardium; omentum; parenchyma (animal tissue); quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; reverse transcription; specific pathogen-free animals; spleen; viral load; virulence; viruses
Abstract:
... Twenty specific pathogen free cats were experimentally infected with a virulent cat-passaged type I field strain of FIPV. Eighteen cats succumbed within 2–4 weeks to effusive abdominal FIP, one survived for 6 weeks, and one seroconverted without outward signs of disease. A profound drop in the absolute count of blood lymphocytes occurred around 2 weeks post-infection (p.i.) in cats with rapid dise ...
DOI:
10.1016/j.vetmic.2014.10.025

8. Organocatalytic Enantioselective Direct Additions of Aldehydes to 4-Vinylpyridines and Electron-Deficient Vinylarenes and Their Synthetic Applications

Author:
Liu, Hongwei,   et al.   ; Wang, Sinan; Li, Xiangmin; Xu, Li; Zhuang, Jinchen; Li, Jian; Li, Hao; Wang, Wei;     Show all 8 Authors
Source:
Journal of the American Chemical Society 2015 v.137 no.6 pp. 2303-2310
ISSN:
1520-5126
Subject:
aldehydes; antagonists; catalysts; catalytic activity; enantiomers; fibrinogen; nitrogen dioxide; nuclear magnetic resonance spectroscopy; pyridines
Abstract:
... We describe a synergistic catalysis strategy for the asymmetric direct addition of simple aldehydes to 4-vinylpyridines. By means of independent activation of weakly electrophilic 4-vinylpyridines by the Brønsted acid CF₃SO₃H (TfOH) and aldehydes by chiral diphenylprolinol tert-butyldimethylsilyl (TBDMS) ether-catalyzed formation of nucleophilic enamines in a cooperative manner, the previously una ...
DOI:
10.1021/ja511143b

9. Erinacerins C–L, Isoindolin-1-ones with α-Glucosidase Inhibitory Activity from Cultures of the Medicinal Mushroom Hericium erinaceus

Author:
Liu, Hongwei,   et al.   ; Wang, Kai; Bao, Li; Qi, Qiuyue; Zhao, Feng; Ma, Ke; Pei, Yunfei;     Show all 7 Authors
Source:
Journal of natural products 2015 v.78 no.1 pp. 146-154
ISSN:
1520-6025
Subject:
Hericium; alpha-glucosidase; cytotoxicity; inhibitory concentration 50; isomers; medicinal fungi; secondary metabolites; spectroscopy; terpenoids
Abstract:
... The well-known edible and medicinal mushroom Hericium erinaceus produces various bioactive secondary metabolites. Ten new isoindolin-1-ones, named erinacerins C–L (1–10), together with (E)-5-(3,7-dimethylocta-2,6-dien-1-yl)-4-hydroxy-6-methoxy-2-phenethylisoindolin-1-one (11) were isolated from the solid culture of H. erinaceus. The structures of new metabolites were established by spectroscopic m ...
DOI:
10.1021/np5004388

10. High loading MnO2 nanowires on graphene paper: Facile electrochemical synthesis and use as flexible electrode for tracking hydrogen peroxide secretion in live cells

Author:
Liu, Hongwei,   et al.   ; Dong, Shuang; Xi, Jiangbo; Wu, Yanan; Fu, Chaoyang; Liu, Hongfang; Xiao, Fei;     Show all 7 Authors
Source:
Analytica chimica acta 2015 v.853 pp. 200-206
ISSN:
0003-2670
Subject:
analytical chemistry; detection limit; diagnostic techniques; electrochemistry; electrodes; environmental monitoring; graphene; graphene oxide; hydrogen peroxide; macrophages; manganese dioxide; nanowires; paper; portable equipment; secretion
Abstract:
... Recent progress in flexible and lightweight electrochemical sensor systems requires the development of paper-like electrode materials. Here, we report a facile and green synthesis of a new type of MnO2 nanowires–graphene nanohybrid paper by one-step electrochemical method. This strategy demonstrates a collection of unique features including the effective electrochemical reduction of graphene oxide ...
DOI:
10.1016/j.aca.2014.08.004

11. Novel helper factors influencing recombinant protein production in Pichia pastoris based on proteomic analysis under simulated microgravity

Author:
Liu, Hongwei,   et al.   ; Huangfu, Jie; Qi, Feng; Zou, Hanfa; Ahmed, Muhammad Saad; Li, Chun;     Show all 6 Authors
Source:
Applied microbiology and biotechnology 2015 v.99 no.2 pp. 653-665
ISSN:
0175-7598
Subject:
microbiology; fermentation; protein folding; gene overexpression; Komagataella pastoris; methanol; microgravity; recombinant proteins; stress response; thiols; biotechnology; transcription (genetics); reporter genes; glycolysis; proteomics; gene expression regulation; peroxidase; oxidative stress
Abstract:
... Microgravity and simulated microgravity (SMG) have quite significant effects on numerous microbial cellular processes. The effects of SMG on the production of recombinant proteins and transcription profiling in prokaryotic and eukaryotic expression host have been investigated. The present study showed that SMG significantly enhanced the specific productivities and activities of the reporter enzyme ...
DOI:
10.1007/s00253-014-6175-8

12. A new proline-containing flavonol glycoside from Caragana leucophloea Pojark

Author:
Liu, Hongwei,   et al.   ; Luo, Chao; Wang, Ali; Wang, Xiaohan; Li, Jing; Wang, Mingan; Wang, Lan; Lai, Daowan; Zhou, Ligang;     Show all 9 Authors
Source:
Natural product research 2015 v.29 no.19 pp. 1811-1819
ISSN:
1478-6427
Subject:
Caenorhabditis elegans; Caragana; aerial parts; anti-infective properties; antioxidant activity; apigenin; hesperidin; isoquercitrin; kaempferol; minimum inhibitory concentration; nematicides; quercetin; quercitrin; rutin; spectroscopy
Abstract:
... One new proline-containing flavonol glycoside, namely kaempferol-3- O -methyl-7- O -β- d -glucopyranosyl-8-(1-methyleneproline)-4′- O -β- d -glucopyranoside (1), together with 15 known flavonoids, 3- O -methylkaempferol (2), 3- O -methylquercetin (3), quercetin (4), kaempferol (5), apigenin (6), rhamnazin (7), astragalin (8), alquds (9), quercitrin (10), rutin (11), isoquercitrin (12), apigetrin ( ...
DOI:
10.1080/14786419.2015.1007974

13. Regulating Underwater Oil Adhesion on Superoleophobic Copper Films through Assembling n-Alkanoic Acids

Author:
Liu, Hongwei,   et al.   ; Cheng, Zhongjun; Lai, Hua; Du, Ying; Fu, Kewei; Li, Chong; Yu, Jianxin; Zhang, Naiqing; Sun, Kening;     Show all 9 Authors
Source:
ACS Applied Materials & Interfaces 2015 v.7 no.36 pp. 20410-20417
ISSN:
1944-8252
Subject:
acids; adhesion; chemistry; chloroform; copper; hexane; mixing; nanomaterials; oils; silicon
Abstract:
... Controlling liquid adhesion on special wetting surface is significant in many practical applications. In this paper, an easy self-assembled monolayer technique was advanced to modify nanostructured copper substrates, and tunable adhesive underwater superoleophobic surfaces were prepared. The surface adhesion can be regulated by simply varying the chain length of the n-alkanoic acids, and the tunab ...
DOI:
10.1021/acsami.5b06374

14. Proteomic analysis of protein methylation in the yeast Saccharomyces cerevisiae

Author:
Liu, Hongwei,   et al.   ; Wang, Keyun; Zhou, Yongjin J.; Cheng, Kai; Mao, Jiawei; Wang, Fangjun; Liu, Wujun; Ye, Mingliang; Zhao, Zongbao K.; Zou, Hanfa;     Show all 10 Authors
Source:
Journal of proteomics 2015 v.114 pp. 226-233
ISSN:
1874-3919
Subject:
Saccharomyces cerevisiae; amino acids; data collection; databases; isotopes; methylation; methyltransferases; nitrogen; oxygen; proteins; proteomics; sulfur; yeasts
Abstract:
... Protein methylation catalyzed by SAM-dependent methyltransferase represents a major PTM involved in many important biological processes. Because methylation can occur on nitrogen, oxygen and sulfur centers and multiple methylation states exist on the nitrogen centers, methylproteome remains poorly documented. Here we present the methylation by isotope labeled SAM (MILS) strategy for a highly-confi ...
DOI:
10.1016/j.jprot.2014.07.032