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- Makino, Shinji, et al. Show all 4 Authors
- Virus research 2015 v.202 pp. 89-100
- Middle East respiratory syndrome coronavirus; gene expression; humans; innate immunity; pathogenesis; vaccine development; viral nonstructural proteins; virulence
- ... The recent emergence of two highly pathogenic human coronaviruses (CoVs), severe acute respiratory syndrome CoV and Middle East respiratory syndrome CoV, has ignited a strong interest in the identification of viral factors that determine the virulence and pathogenesis of CoVs. The nonstructural protein 1 (nsp1) of CoVs has attracted considerable attention in this regard as a potential virulence fa ...