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- Mitchell, Trevor R., et al. Show all 14 Authors
- Food additives & contaminants 2015 v.32 no.6 pp. 934-949
- absorbance; animal models; biomarkers; blood; blood volume; ceramides; corn; formic acid; fumonisins; half life; humans; males; mice; neural tube defects; paper; protein content; risk factors; tissues; urine
- ... Fumonisins (FB) are mycotoxins found in maize. They are hypothesised risk factors for neural tube defects (NTDs) in humans living where maize is a dietary staple. In LM/Bc mice, FB ₁-treatment of pregnant dams induces NTDs and results in increased levels of sphingoid base 1-phosphates in blood and tissues. The increased level of sphingoid base 1-phosphates in blood is a putative biomarker for FB ₁ ...