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- Reed, Robin, et al. Show all 2 Author
- Proceedings of the National Academy of Sciences of the United States of America 2015 v.112 no.28 pp. 8608-8613
- DNA-directed RNA polymerase; amyotrophic lateral sclerosis; ribonucleoproteins
- ... The protein fused-in-sarcoma (FUS) is mutated to cause the neurodegenerative disease amyotrophic lateral sclerosis, but its normal cellular role remains to be understood. Previous work showed that FUS associates with both RNA polymerase II (RNAP II) and the essential splicing factor U1 small nuclear ribonucleoprotein (snRNP). Here we were able to directly investigate the functional significance of ...
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