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You searched for: Author "Shin, Chan Young" Remove constraint Author: "Shin, Chan Young" Publication Year 2015 Remove constraint Publication Year: 2015
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1. High sucrose consumption during pregnancy induced ADHD-like behavioral phenotypes in mice offspring

Author:
Shin, Chan Young,   et al.   ; Choi, Chang Soon; Kim, Pitna; Park, Jin Hee; Gonzales, Edson Luck T.; Kim, Ki Chan; Cho, Kyu Suk; Ko, Mee Jung; Yang, Sung Min; Seung, Hana; Han, Seol-Heui; Ryu, Jong Hoon; Cheong, Jae Hoon;     Show all 13 Authors
Source:
The Journal of nutritional biochemistry 2015 v.26 pp. 1520-1526
ISSN:
0955-2863
Subject:
dopamine; dopamine receptors; dose response; environmental factors; fructose; gene expression; locomotion; maternal nutrition; messenger RNA; mice; oral administration; phenotype; pregnancy; progeny; protein synthesis; risk factors; sucrose; weaning; weight gain
Abstract:
... In recent years, the average consumption of sugar in humans from all ages has remarkably increased, exceeding the recommended limit. Pregnancy is a critical time for the global development of offsprings who are vulnerable to the deleterious effects of environmental factors. In this study, we investigated whether high sucrose consumption during pregnancy could affect the attention-deficit hyperacti ...
DOI:
10.1016/j.jnutbio.2015.07.018

2. Propofol treatment modulates neurite extension regulated by immunologically challenged rat primary astrocytes: a possible role of PAI-1

Author:
Shin, Chan Young,   et al.   ; Ko, Hyun Myung; Joo, So Hyun; Lee, Sung Hoon; Kim, Hee Jin; Lee, Seung-Hyun; Cheong, Jae Hoon; Ryu, Jong Hoon; Kim, Jeong Min; Koo, Bon-Nyeo;     Show all 10 Authors
Source:
Archives of pharmacal research 2015 v.38 no.4 pp. 556-565
ISSN:
0253-6269
Subject:
Western blotting; anesthetics; astrocytes; brain; casein; cell viability; mitogen-activated protein kinase; neurons; neuroplasticity; neuroprotective effect; neurotoxicity; plasminogen activator inhibitors; rats; reverse transcriptase polymerase chain reaction; t-plasminogen activator
Abstract:
... Propofol, a widely used anesthetic, regulates neurological processes including neurotoxicity, neuroprotection, glial activation, synaptic plasticity and neuronal maturation. Tissue plasminogen activator/tissue plasminogen activator inhibitor-1 (tPA/PAI-1) in CNS acts as a neuromodulator regulating synaptic plasticity, neurite outgrowth, seizure spreading and cell survival. Here, we investigated th ...
DOI:
10.1007/s12272-014-0442-1