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- Soheili, Vahid, et al. Show all 4 Authors
- Microbial pathogenesis 2015 v.89 pp. 73-78
- Gram-negative bacteria; Pseudomonas aeruginosa; active sites; animal pathogens; biofilm; cystic fibrosis; death; elastase; meloxicam; molecular models; nonsteroidal anti-inflammatory agents; patients; proteins; pyocyanin; quorum sensing; rhamnolipids; virulence
- ... Pseudomonas aeruginosa is an opportunistic human pathogen and a common Gram-negative bacterium in hospital-acquired infections. It causes death in many burn victims, cystic-fibrosis and neutropenic-cancer patients. It is known that P. aeruginosa biofilm maturation and production of cell-associated and extracellular virulence factors such as pyocyanin, elastase and rhamnolipids are under the contro ...