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- Wright, Ernest M., et al. Show all 11 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2015 v.112 no.30 pp. E4111
- animal models; glucose; glucose transporters; image analysis; neoplasm cells; patients; positron-emission tomography; prostatic neoplasms; viability
- ... Cancers require high amounts of glucose to grow and survive, and dogma is that uptake is facilitated by passive glucose transporters (GLUTs). We have identified a new mechanism to import glucose into pancreatic and prostate cancer cells, namely active glucose transport mediated by sodium-dependent glucose transporters (SGLTs). This means that the specific radioactive imaging probe for SGLTs, α-met ...
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