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- Ye, Yuzhen, et al. Show all 3 Authors
- Genome biology 2015 v.16 no.1 pp. 243
- data collection; genes; intestinal microorganisms; metagenomics; microbial communities; noninsulin-dependent diabetes mellitus; phylogeny
- ... Comparative metagenomics remains challenging due to the size and complexity of metagenomic datasets. Here we introduce subtractive assembly, a de novo assembly approach for comparative metagenomics that directly assembles only the differential reads that distinguish between two groups of metagenomes. Using simulated datasets, we show it improves both the efficiency of the assembly and the assembly ...