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- Wu, Shuting, et al. Show all 8 Authors
- Virology journal 2014 v.11 no.1 pp. 2439
- interferon-gamma; viral load; vaccination; immunity; Muromegalovirus; DNA; spleen; splenocytes; viruses; people; virulence; CD8-positive T-lymphocytes; pathogens; Human betaherpesvirus 5; intramuscular injection; lethal dose 50; antigens; disease control; mice; control methods; neutralizing antibodies; DNA helicases; weight loss; electroporation; immunoblotting; proteins; survival rate; animal models; salivary glands; recombinant vaccines
- ... BACKGROUND: Human cytomegalovirus (HCMV) causes serious HCMV-related diseases in immunocompromised people. Vaccination is the most effective measure to control infection with the pathogen, yet no vaccine has been licensed till now. We performed a head-to-head comparison of the protective abilities of multiple DNA vaccines in murine model of murine cytomegalovirus (MCMV) infection. METHODS: Five DN ...
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