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- Author:
- Cormier, Hubert; Rudkowska, Iwona; Lemieux, Simone; Couture, Patrick; Julien, Pierre; Vohl, Marie-Claude
- Source:
- Genes & nutrition 2014 v.9 no.6 pp. 437
- ISSN:
- 1555-8932
- Subject:
- polyunsaturated fatty acids, etc ; enzyme activity; fish oils; gas chromatography; genes; metabolism; phospholipids; Show all 7 Subjects
- Abstract:
- ... Polymorphisms (SNPs) within the FADS gene cluster and the ELOVL gene family are believed to influence enzyme activities after an omega-3 (n-3) fatty acid (FA) supplementation. The objectives of the study are to test whether an n-3 supplementation is associated with indexes of desaturase and elongase activities in addition to verify whether SNPs in the FADS gene cluster and the ELOVL gene family mo ...
- DOI:
- 10.1007/s12263-014-0437-z
- PubMed:
- 25367143
- PubMed Central:
- PMC4235832
- http://dx.doi.org/10.1007/s12263-014-0437-z
- Author:
- Tungen, Jørn E.; Aursnes, Marius; Vik, Anders; Ramon, Sesquile; Colas, Romain A.; Dalli, Jesmond; Serhan, Charles N.; Hansen, Trond V.
- Source:
- Journal of natural products 2014 v.77 no.10 pp. 2241-2247
- ISSN:
- 1520-6025
- Subject:
- polyunsaturated fatty acids, etc ; anti-inflammatory activity; chemotaxis; hydrolysis; macrophages; metabolism; metabolites; phagocytosis; Show all 8 Subjects
- Abstract:
- ... Protectin D1 (PD1 (3)), a C22-dihydroxylated polyunsaturated fatty acid biosynthesized from all-Z-docosahexaenoic acid, belongs to the new family of endogenous mediators referred to as specialized pro-resolving lipid mediators. PD1 (3) is a natural product that displays potent anti-inflammatory properties together with pro-resolving actions including inhibition of polymorphonuclear leukocyte (PMN) ...
- DOI:
- 10.1021/np500498j
- PubMed:
- 25247845
- PubMed Central:
- PMC4208671
- http://dx.doi.org/10.1021%2Fnp500498j
- Author:
- Tyurina, Yulia Y.; Domingues, Rosario M.; Tyurin, Vladimir A.; Maciel, Elisabete; Domingues, Pedro; Amoscato, Andrew A.; Bayir, Hülya; Kagan, Valerian E.
- Source:
- Chemistry and physics of lipids 2014 v.179 pp. 3-10
- ISSN:
- 0009-3084
- Subject:
- polyunsaturated fatty acids, etc ; cardiolipins; computer software; immune response; instrumentation; mammals; methodology; oxidation; Show all 8 Subjects
- Abstract:
- ... Cardiolipins, a class of mitochondria-specific lipid molecules, is one of the most unusual and ancient phospholipids found in essentially all living species. Typical of mammalian cells is the presence of vulnerable to oxidation polyunsaturated fatty acid resides in CL molecules. The overall role and involvement of cardiolipin oxidation (CLox) products in major intracellular signaling as well as ex ...
- DOI:
- 10.1016/j.chemphyslip.2013.12.003
- PubMed:
- 24333544
- PubMed Central:
- PMC4025908
- https://dx.doi.org/10.1016/j.chemphyslip.2013.12.003
4. The PNPLA3 Ile148Met interacts with overweight and dietary intakes on fasting triglyceride levels
- Author:
- Stojkovic, Ivana A.; Ericson, Ulrika; Rukh, Gull; Riddestråle, Martin; Romeo, Stefano; Orho-Melander, Marju
- Source:
- Genes & nutrition 2014 v.9 no.2 pp. 388
- ISSN:
- 1555-8932
- Subject:
- polyunsaturated fatty acids, etc ; diabetes; diet history; dietary carbohydrate; fasting; genes; lipid content; overweight; sucrose; triacylglycerols; Show all 10 Subjects
- Abstract:
- ... The Ile148Met (rs738409, G-allele) in the patatin-like phospholipase domain-containing protein 3 gene (PNPLA3) associates with liver fat content and may lead to loss-of-function (hydrolysis) or gain-of-function (CoA-dependent lysophosphatidic acid acyltransferase) defects. PNPLA3 is up-regulated by dietary carbohydrates, and interactions between rs738409 and carbohydrates, and sugar and ω6:ω3-poly ...
- DOI:
- 10.1007/s12263-014-0388-4
- PubMed:
- 24563329
- PubMed Central:
- PMC3968290
- http://dx.doi.org/10.1007/s12263-014-0388-4
- Author:
- Yang, Peng; Belikova, Natalia A.; Billheimer, Jeff; Rader, Daniel J.; Hill, John S.; Subbaiah, Papasani V.
- Source:
- Lipids 2014 v.49 no.10 pp. 987-996
- ISSN:
- 0024-4201
- Subject:
- polyunsaturated fatty acids, etc ; high density lipoprotein; humans; hydrolysis; low density lipoprotein; phosphatidylcholines; sphingomyelins; very low density lipoprotein; Show all 8 Subjects
- Abstract:
- ... Endothelial lipase (EL) is a major determinant of plasma HDL concentration, its activity being inversely proportional to HDL levels. Although it is known that it preferentially acts on HDL compared to LDL and VLDL, the basis for this specificity is not known. Here we tested the hypothesis that sphingomyelin, a major phospholipid in lipoproteins is a physiological inhibitor of EL, and that the pref ...
- DOI:
- 10.1007/s11745-014-3944-1
- PubMed:
- 25167836
- PubMed Central:
- PMC4175046
- http://dx.doi.org/10.1007/s11745-014-3944-1
- Author:
- Amoscato, A. A.; Sparvero, L. J.; He, R. R.; Watkins, S.; Bayir, H.; Kagan, V. E.
- Source:
- Analytical chemistry 2014 v.86 no.13 pp. 6587-6595
- ISSN:
- 1520-6882
- Subject:
- polyunsaturated fatty acids, etc ; biogeography; cardiolipins; chromosome mapping; cortex; crosslinking; hippocampus; image analysis; mass spectrometry; mitochondria; phosphatidylcholines; phospholipase C; physiology; thalamus; Show all 14 Subjects
- Abstract:
- ... MALDI imaging mass spectrometry (MALDI-IMS) has been used successfully in mapping different lipids in tissue sections, yet existing protocols fail to detect the diverse species of mitochondria-unique cardiolipins (CLs) in the brain which are essential for cellular and mitochondrial physiology. We have developed methods enabling the imaging of individual CLs in brain tissue. This was achieved by el ...
- DOI:
- 10.1021/ac5011876
- PubMed:
- 24949523
- PubMed Central:
- PMC4082390
- http://dx.doi.org/10.1021%2Fac5011876
- Author:
- Clarke, Shannon E.; Kang, Jing X.; Ma, David W. L.
- Source:
- Transgenic research 2014 v.23 no.3 pp. 489-501
- ISSN:
- 0962-8819
- Subject:
- polyunsaturated fatty acids, etc ; humans; hybrids; kidneys; liver; mice; models; omega-3 fatty acids; omega-6 fatty acids; phospholipids; tamoxifen; transgenes; Show all 12 Subjects
- Abstract:
- ... Fat-1 transgenic mice, which endogenously convert n-6 PUFA to n-3 PUFA, are a useful tool in health research; however with this model timing of n-3 PUFA enrichment cannot be directly controlled. To add such capability, the novel Cre-recombinase inducible fat-1 (iFat1) transgenic mouse has been developed. The aim of this study was to characterize the utility of the iFat1 transgene as a model of Cre ...
- DOI:
- 10.1007/s11248-014-9788-x
- PubMed:
- 24622775
- PubMed Central:
- PMC4010720
- http://dx.doi.org/10.1007/s11248-014-9788-x
- Author:
- Teng, Kim-Tiu; Chang, Chee-Yan; Chang, Lin Faun; Nesaretnam, Kalanithi
- Source:
- Nutrition journal 2014 v.13 no.1 pp. 12
- ISSN:
- 1475-2891
- Subject:
- polyunsaturated fatty acids, etc ; anti-inflammatory activity; clinical trials; dietary fat; inflammation; obesity; omega-3 fatty acids; omega-6 fatty acids; postprandial state; saturated fatty acids; weight loss; Show all 11 Subjects
- Abstract:
- ... Obesity plays a pivotal role in the development of low-grade inflammation. Dietary fatty acids are important modulators of inflammatory responses. Saturated fatty acids (SFA) and n-6 polyunsaturated fatty acids (PUFA) have been reported to exert pro-inflammatory effects. n-3 PUFA in particular, possess anti-inflammatory properties. Numerous clinical studies have been conducted over decades to inve ...
- DOI:
- 10.1186/1475-2891-13-12
- PubMed:
- 24476102
- PubMed Central:
- PMC3922162
- http://dx.doi.org/10.1186/1475-2891-13-12
- Author:
- Filippi, Anna Rita; Amodio, Emanuele; Napoli, Giuseppe; Breda, João; Bianco, Antonino; Jemni, Monèm; Censi, Laura; Mammina, Caterina; Tabacchi, Garden
- Source:
- Nutrition journal 2014 v.13 no.1 pp. 119
- ISSN:
- 1475-2891
- Subject:
- polyunsaturated fatty acids, etc ; Internet; adolescents; correlation; energy; ethanol; food frequency questionnaires; food groups; monitoring; nutrient content; nutrients; obesity; secondary education; soft drinks; sugars; white bread; Italy; Show all 17 Subjects
- Abstract:
- ... BACKGROUND: A new food frequency questionnaire (FFQ) has been recently developed within the Italian Adolescents and Surveillance System for the Obesity prevention (ASSO) Project; it was found to be appropriate for ranking adolescents in food and nutrient levels of intake. The aim of this study was to assess the relative and absolute reproducibility of the ASSO-FFQ for 24 food groups, energy and 52 ...
- DOI:
- 10.1186/1475-2891-13-119
- PubMed:
- 25518876
- PubMed Central:
- PMC4320587
- http://dx.doi.org/10.1186/1475-2891-13-119
- Author:
- Curhan, Sharon G; Eavey, Roland D; Wang, Molin; Rimm, Eric B; Curhan, Gary C
- Source:
- TheAmerican journal of clinical nutrition 2014 v.100 no.5 pp. 1371-1377
- ISSN:
- 0002-9165
- Subject:
- polyunsaturated fatty acids, etc ; questionnaires; nurses; fish consumption; women; cohort studies; risk factors; regression analysis; fatty fish; clinical nutrition; omega-3 fatty acids; hearing disorders; Show all 12 Subjects
- Abstract:
- ... Background: Acquired hearing loss is common and often disabling, yet limited prospective data exist on potentially modifiable risk factors. Evidence suggests that higher intake of fish and long-chain omega-3 (n−3) polyunsaturated fatty acids (PUFAs) may be associated with a lower risk of hearing loss, but prospective information on these relations is limited.Objective: We prospectively examined th ...
- DOI:
- 10.3945/ajcn.114.091819
- PubMed:
- 25332335
- PubMed Central:
- PMC4196487
- http://dx.doi.org/10.3945/ajcn.114.091819
- Author:
- Ran-Ressler, Rinat Rivka; Bae, SangEun; Lawrence, Peter; Wang, Dong Hao; Thomas Brenna, J.
- Source:
- The British journal of nutrition 2014 v.112 no.4 pp. 565-572
- ISSN:
- 1475-2662
- Subject:
- polyunsaturated fatty acids, etc ; beef; branched chain fatty acids; chickens; fatty acid composition; food intake; low fat foods; milk; milk fat; miso; pork; ruminants; salmon; sauerkraut; United States; Show all 15 Subjects
- Abstract:
- ... Branched-chain fatty acids (BCFA) are bioactive food components that constitute about 2 % of fatty acids in cows' milk fat. There are few systematic data available on the BCFA content of other foods to estimate dietary intakes. In the present study, we report BCFA distribution and content of fresh and processed foods representing the major foods in the American diet and estimate BCFA intake. BCFA ...
- DOI:
- 10.1017/S0007114514001081
- PubMed:
- 24830474
- PubMed Central:
- PMC4381348
- https://dx.doi.org/10.1017/S0007114514001081
- Author:
- Holowka, David; Korzeniowski, Marek K.; Bryant, Kirsten L.; Baird, Barbara
- Source:
- BBA - Molecular and Cell Biology of Lipids 2014 v.1841 pp. 1210-1216
- ISSN:
- 1388-1981
- Subject:
- polyunsaturated fatty acids, etc ; calcium; calcium channels; carbon; crosslinking; electrostatic interactions; energy transfer; exocytosis; linoleic acid; mast cells; oligomerization; plasma membrane; stearic acid; Show all 13 Subjects
- Abstract:
- ... Polyunsaturated fatty acids (PUFAs) have been found to be effective inhibitors of cell signaling in numerous contexts, and we find that acute addition of micromolar PUFAs such as linoleic acid effectively inhibit of Ca2+ responses in mast cells stimulated by antigen-mediated crosslinking of FcεRI or by the SERCA pump inhibitor, thapsigargin. In contrast, the saturated fatty acid, stearic acid, wit ...
- DOI:
- 10.1016/j.bbalip.2014.04.006
- PubMed:
- 24769339
- PubMed Central:
- PMC4069244
- http://dx.doi.org/10.1016/j.bbalip.2014.04.006
- Author:
- Curtis, Tanya Y.; Postles, Jennifer; Halford, Nigel G.
- Source:
- Journal of cereal science 2014 v.59 no.3 pp. 382-392
- ISSN:
- 0733-5210
- Subject:
- polyunsaturated fatty acids, etc ; Maillard reaction; acrylamides; adverse effects; analytical methods; equipment; food industry; foods; grain products; hydrogenation; lipid peroxidation; product quality; risk; supply chain; Show all 14 Subjects
- Abstract:
- ... Processing contaminants may be defined as substances that are produced in a food when it is cooked or processed, are not present or are present at much lower concentrations in the raw, unprocessed food, and are undesirable either because they have an adverse effect on product quality or because they are potentially harmful. The presence of very low levels of processing contaminants in common foods ...
- DOI:
- 10.1016/j.jcs.2013.11.002
- PubMed:
- 24882936
- PubMed Central:
- PMC4026124
- https://dx.doi.org/10.1016/j.jcs.2013.11.002
- Author:
- Meidtner, Karina; Fisher, Eva; Ängquist, Lars; Holst, Claus; Vimaleswaran, Karani S.; Boer, Jolanda M. A.; Halkjær, Jytte; Masala, Giovanna; Østergaard, Jane N.; Mortensen, Lotte M.; van der A, Daphne L.; Tjønneland, Anne; Palli, Domenico; Overvad, Kim; Wareham, Nicholas J.; Loos, Ruth J. F.; Sørensen, Thorkild I. A.; Boeing, Heiner
- Source:
- Genes & nutrition 2014 v.9 no.2 pp. 385
- ISSN:
- 1555-8932
- Subject:
- polyunsaturated fatty acids, etc ; body mass index; carbohydrate intake; energy balance; genes; genetic variation; linear models; lipid metabolism; regression analysis; single nucleotide polymorphism; waist circumference; weight gain; Show all 12 Subjects
- Abstract:
- ... We analysed single nucleotide polymorphisms (SNPs) tagging the genetic variability of six candidate genes (ATF6, FABP1, LPIN2, LPIN3, MLXIPL and MTTP) involved in the regulation of hepatic lipid metabolism, an important regulatory site of energy balance for associations with body mass index (BMI) and changes in weight and waist circumference. We also investigated effect modification by sex and die ...
- DOI:
- 10.1007/s12263-014-0385-7
- PubMed:
- 24496996
- PubMed Central:
- PMC3968289
- http://dx.doi.org/10.1007/s12263-014-0385-7
- Author:
- Wells, Rachel; Trick, Martin; Soumpourou, Eleni; Clissold, Leah; Morgan, Colin; Werner, Peter; Gibbard, Carl; Clarke, Matthew; Jennaway, Richard; Bancroft, Ian
- Source:
- Molecular breeding 2014 v.33 no.2 pp. 349-362
- ISSN:
- 1380-3743
- Subject:
- polyunsaturated fatty acids, etc ; Arabidopsis thaliana; Brassica napus var. napus; alleles; ancestry; cultivars; ethyl methanesulfonate; loci; mutants; mutation; oleic acid; polyploidy; seed oils; seeds; stearoyl-CoA desaturase; Show all 15 Subjects
- Abstract:
- ... Many important plant species have polyploidy in their recent ancestry, complicating inferences about the genetic basis of trait variation. Although the principal locus controlling the proportion of polyunsaturated fatty acids (PUFAs) in seeds of Arabidopsis thaliana is known (fatty acid desaturase 2; FAD2), commercial cultivars of a related crop, oilseed rape (Brassica napus), with very low PUFA c ...
- DOI:
- 10.1007/s11032-013-9954-5
- PubMed:
- 24489479
- PubMed Central:
- PMC3901927
- http://dx.doi.org/10.1007/s11032-013-9954-5
- Author:
- Feng, Shi; Powell, Shane M.; Wilson, Richard; Bowman, John P.
- Source:
- Genome biology and evolution 2014 v.6 no.1 pp. 133-148
- Subject:
- polyunsaturated fatty acids, etc ; Psychroflexus torquis; apoptosis; biosynthesis; ecosystems; exopolysaccharides; genomic islands; horizontal gene transfer; ice; proteins; proteomics; pseudogenes; psychrophilic bacteria; translation (genetics); Antarctic region; Arctic region; Show all 16 Subjects
- Abstract:
- ... Sea ice is a highly dynamic and productive environment that includes a diverse array of psychrophilic prokaryotic and eukaryotic taxa distinct from the underlying water column. Because sea ice has only been extensive on Earth since the mid-Eocene, it has been hypothesized that bacteria highly adapted to inhabit sea ice have traits that have been acquired through horizontal gene transfer (HGT). Her ...
- DOI:
- 10.1093/gbe/evt209
- PubMed:
- 24391155
- PubMed Central:
- PMC3914696
- http://dx.doi.org/10.1093/gbe/evt209
- Author:
- Wakai, Kenji; Naito, Mariko; Date, Chigusa; Iso, Hiroyasu; Tamakoshi, Akiko
- Source:
- Nutrition & metabolism 2014 v.11 no.1 pp. 586
- ISSN:
- 1743-7075
- Subject:
- polyunsaturated fatty acids, etc ; risk; prospective studies; Japanese people; energy; dietary fat; cardiovascular diseases; men; women; confidence interval; monounsaturated fatty acids; mortality; fat intake; saturated fatty acids; food frequency questionnaires; death; dietary recommendations; Japan; Show all 18 Subjects
- Abstract:
- ... BACKGROUND: It may be useful to examine associations of fat intakes with total mortality as a basis for dietary recommendations. We aimed to elucidate associations between dietary fat and total mortality among Japanese populations with low fat intake. METHODS: We conducted a prospective study consisting of 58,672 men and women aged 40 to 79 years. Fat intakes were estimated using a food frequency ...
- DOI:
- 10.1186/1743-7075-11-12
- PubMed:
- 24597664
- PubMed Central:
- PMC3973975
- http://dx.doi.org/10.1186/1743-7075-11-12
- Author:
- Verbrugghe, Adronie; Janssens, Geert PJ; Van de Velde, Hannelore; Cox, Eric; De Smet, Stefaan; Vlaeminck, Bruno; Hesta, Myriam
- Source:
- BMC veterinary research 2014 v.10 no.1 pp. 909
- ISSN:
- 1746-6148
- Subject:
- polyunsaturated fatty acids, etc ; additives; adults; alpha-tocopherol; amyloid; antioxidants; blood serum; carnivores; cats; chickens; dietary fat; fatty acid composition; fish; high fat diet; inflammation; lard; models; omega-6 fatty acids; oxidative stress; pork; salmon oil; thiobarbituric acid-reactive substances; Show all 22 Subjects
- Abstract:
- ... BACKGROUND: Oxidative stress and inflammation can be altered by dietary factors in various species. However, little data are available in true carnivorous species such as domestic cats. As numerous anti-inflammatory and anti-oxidative additives become available and might be of use in cats with chronic low-grade inflammatory diseases, the current study aimed to develop a model of diet-induced infla ...
- DOI:
- 10.1186/1746-6148-10-104
- PubMed:
- 24885092
- PubMed Central:
- PMC4016662
- http://dx.doi.org/10.1186/1746-6148-10-104
- Author:
- Maximova, Siela N; Florez, Sergio; Shen, Xiangling; Niemenak, Nicolas; Zhang, Yufan; Curtis, Wayne; Guiltinan, Mark J
- Source:
- BMC plant biology 2014 v.14 no.1 pp. 185
- ISSN:
- 1471-2229
- Subject:
- polyunsaturated fatty acids, etc ; ethylene; genes; flavonoids; fruit trees; Theobroma cacao; gene expression; secondary metabolites; genotype; gene expression regulation; tissues; somatic embryos; chocolate; messenger RNA; auxins; fatty acid metabolism; biosynthesis; microarray technology; farmers; breeding; cotyledons; somatic embryogenesis; seed storage; seed development; Show all 24 Subjects
- Abstract:
- ... BACKGROUND: Theobroma cacao L. is a tropical fruit tree, the seeds of which are used to create chocolate. In vitro somatic embryogenesis (SE) of cacao is a propagation system useful for rapid mass-multiplication to accelerate breeding programs and to provide plants directly to farmers. Two major limitations of cacao SE remain: the efficiency of embryo production is highly genotype dependent and th ...
- DOI:
- 10.1186/1471-2229-14-185
- PubMed:
- 25030026
- PubMed Central:
- PMC4110631
- https://dx.doi.org/10.1186/1471-2229-14-185
- Author:
- Dick, Morag F; Hurford, Jennifer; Lei, Sha; Mustonen, Anne-Mari; Nieminen, Petteri; Rouvinen-Watt, Kirsti
- Source:
- Acta veterinaria scandinavica 2014 v.56 no.1 pp. 924
- ISSN:
- 1751-0147
- Subject:
- polyunsaturated fatty acids, etc ; Neovison vison; body fat; canola oil; dietary fat; etiology; fasting; fatty liver; herring; mink; monounsaturated fatty acids; obesity; omega-3 fatty acids; omega-6 fatty acids; oxidation; weight gain; Show all 16 Subjects
- Abstract:
- ... BACKGROUND: Rapid body fat mobilization, obesity, and an inadequate supply of n-3 polyunsaturated fatty acids (PUFA) have been suggested to play roles in the etiology of fatty liver in the American mink (Neovison vison). This study examined the effects of feeding intensity and dietary fat source on fatty liver induced by fasting. In a multi-factorial design, 3 different fat sources (herring oil, r ...
- DOI:
- 10.1186/1751-0147-56-5
- PubMed:
- 24438337
- PubMed Central:
- PMC3896742
- http://dx.doi.org/10.1186/1751-0147-56-5
- Author:
- Sevane, Natalia; Levéziel, Hubert; Nute, Geoffrey R; Sañudo, Carlos; Valentini, Alessio; Williams, John; Dunner, Susana
- Source:
- Journal of animal science and biotechnology 2014 v.5 no.1 pp. 108
- ISSN:
- 2049-1891
- Subject:
- polyunsaturated fatty acids, etc ; beef; beef industry; beef quality; breeds; bulls; correlation; fatty acid composition; flavor; gene frequency; juiciness; lipid content; nutrients; phospholipids; principal component analysis; red meat; sensory evaluation; single nucleotide polymorphism; texture; triacylglycerols; Show all 20 Subjects
- Abstract:
- ... BACKGROUND: Consuming moderate amounts of lean red meat as part of a balanced diet valuably contributes to intakes of essential nutrients. In this study, we merged phenotypic and genotypic information to characterize the variation in lipid profile and sensory parameters and to represent the diversity among 15 cattle populations. Correlations between fat content, organoleptic characteristics and li ...
- DOI:
- 10.1186/2049-1891-5-20
- PubMed:
- 24735897
- PubMed Central:
- PMC4019361
- http://dx.doi.org/10.1186/2049-1891-5-20
- Author:
- Chen, Gao; Qu, Shujie; Wang, Qiang; Bian, Fei; Peng, Zhenying; Zhang, Yan; Ge, Haitao; Yu, Jinhui; Xuan, Ning; Bi, Yuping; He, Qingfang
- Source:
- Biotechnology for biofuels 2014 v.7 no.1 pp. 32
- ISSN:
- 1754-6834
- Subject:
- polyunsaturated fatty acids, etc ; linoleic acid; gene overexpression; Synechocystis; fatty acid composition; Fusarium fujikuroi; Mortierella alpina; nutrition; biochemical pathways; nutritive value; oils; genes; photosynthesis; omega-3 fatty acids; stearoyl-CoA desaturase; Show all 15 Subjects
- Abstract:
- ... BACKGROUND: Polyunsaturated fatty acids (PUFAs), which contain two or more double bonds in their backbone, are the focus of intensive global research, because of their nutritional value, medicinal applications, and potential use as biofuel. However, the ability to produce these economically important compounds is limited, because it is both expensive and technically challenging to separate omega-3 ...
- DOI:
- 10.1186/1754-6834-7-32
- PubMed:
- 24581179
- PubMed Central:
- PMC3941260
- https://dx.doi.org/10.1186/1754-6834-7-32
- Author:
- Camargo, Antonio; Meneses, María E.; Pérez-Martínez, Pablo; Delgado-Lista, Javier; Rangel-Zúñiga, Oriol A.; Marín, Carmen; Almadén, Yolanda; Yubero-Serrano, Elena M.; González-Guardia, Lorena; Fuentes, Francisco; Tinahones, Francisco J.; Roche, Helen M.; Malagón, María M.; Pérez-Jiménez, Francisco; López-Miranda, José
- Source:
- Genes & nutrition 2014 v.9 no.4 pp. 409
- ISSN:
- 1555-8932
- Subject:
- polyunsaturated fatty acids, etc ; adipose tissue; body fat; dietary fat; fasting; fatty acid composition; genes; homeostasis; lipogenesis; lipolysis; metabolic syndrome; omega-3 fatty acids; patients; stearoyl-CoA desaturase; triacylglycerol lipase; Show all 15 Subjects
- Abstract:
- ... Adipose tissue (AT) is a key organ in the regulation of total body lipid homeostasis, which is responsible for the storage and release of fatty acids according to metabolic needs. We aimed to investigate the effect of the quantity and quality of dietary fat on the lipogenesis and lipolysis processes in the AT of metabolic syndrome (MetS) patients. A randomized, controlled trial conducted within th ...
- DOI:
- 10.1007/s12263-014-0409-3
- PubMed:
- 24895107
- PubMed Central:
- PMC4169067
- http://dx.doi.org/10.1007/s12263-014-0409-3
- Author:
- Strain, J. J.
- Source:
- Nutrition bulletin 2014 v.39 no.2 pp. 181-186
- ISSN:
- 1471-9827
- Subject:
- polyunsaturated fatty acids, etc ; adverse effects; child development; education; epidemiological studies; fetal development; fish; fish consumption; issues and policy; methylmercury compounds; neurodevelopment; nutrients; pregnancy; risk; toxicity; whales; Faroe Islands; Seychelles; United Kingdom; United States; Show all 20 Subjects
- Abstract:
- ... This article is based on the British Nutrition Foundation's Annual Lecture 2013, which focused on maternal fish consumption and the effects of methylmercury (MeHg) on fetal development, with respect to current guidance and policy on fish consumption during pregnancy. Fish makes a valuable contribution to nutrient intakes across the globe and is the primary protein source for many individuals, part ...
- DOI:
- 10.1111/nbu.12088
- PubMed:
- 25132804
- PubMed Central:
- PMC4131443
- http://dx.doi.org/10.1111/nbu.12088
- Author:
- Walker, Celia G.; Browning, Lucy M.; Mander, Adrian P.; Madden, Jackie; West, Annette L.; Calder, Philip C.; Jebb, Susan A.
- Source:
- The British journal of nutrition 2014 v.111 no.4 pp. 679-689
- ISSN:
- 1475-2662
- Subject:
- polyunsaturated fatty acids, etc ; adipose tissue; blood plasma; body mass index; cholesteryl esters; compliance; dietary recommendations; erythrocytes; fatty acid composition; fatty fish; females; free fatty acids; gender differences; humans; linear models; males; omega-3 fatty acids; phosphatidylcholines; regression analysis; Show all 19 Subjects
- Abstract:
- ... The aim of the present study was to determine whether age and sex influence both the status and incorporation of EPA and DHA into blood plasma, cells and tissues. The study was a double-blind, randomised, controlled intervention trial, providing EPA plus DHA equivalent to 0, 1, 2 or 4 portions of oily fish per week for 12 months. The participants were stratified by age and sex. A linear regression ...
- DOI:
- 10.1017/S0007114513002985
- PubMed:
- 24063767
- PubMed Central:
- PMC4351921
- https://dx.doi.org/10.1017/S0007114513002985
- Author:
- Kim, Wooki; Barhoumi, Rola; McMurray, David N.; Chapkin, Robert S.
- Source:
- The British journal of nutrition 2014 v.111 no.2 pp. 254-260
- ISSN:
- 1475-2662
- Subject:
- polyunsaturated fatty acids, etc ; CD4-positive T-lymphocytes; corn oil; dietary nutrient sources; fish oils; gangliosides; immunological synapse; liquid membranes; mice; omega-3 fatty acids; ovalbumin; plasma membrane; protein kinase C; transgenic animals; Show all 14 Subjects
- Abstract:
- ... We have demonstrated previously that n-3 PUFA endogenously produced by fat-1 transgenic mice regulate CD4⁺ T-cell function by affecting the formation of lipid rafts, liquid-ordered mesodomains in the plasma membrane. In the present study, we tested the effects of dietary sources of n-3 PUFA, i.e. fish oil (FO) or purified DHA, when compared with an n-6 PUFA-enriched maize oil control diet in DO11. ...
- DOI:
- 10.1017/S0007114513002444
- PubMed:
- 23962659
- PubMed Central:
- PMC4327854
- https://dx.doi.org/10.1017/S0007114513002444
- Author:
- Manor, Meghan L.; Weber, Gregory M.; Cleveland, Beth M.; Kenney, P. Brett
- Source:
- Aquaculture 2014 v.418-419 pp. 17
- ISSN:
- 0044-8486
- Subject:
- polyunsaturated fatty acids, etc ; Oncorhynchus mykiss; adipose tissue; biomass; diploidy; energy; fatty acid composition; fatty acid metabolism; females; fish feeding; gonads; liver; monounsaturated fatty acids; muscles; ovarian development; ovulation; restricted feeding; satiety; saturated fatty acids; sexual development; triploidy; trout; Show all 22 Subjects
- Abstract:
- ... Sexual maturation is an energy demanding, physiological process that alters growth efficiency and compromises muscle quality in many food-fish species. Lipid mobilization supplies energy required for this process. To study the effect of ration level on fatty acid composition, diploid (2N) rainbow trout, approaching ovulation, were fed at 0.25 and 0.50% of tank biomass/day and to apparent satiation ...
- Handle:
- 10113/58329
- DOI:
- 10.1016/j.aquaculture.2013.09.023
- https://dx.doi.org/10.1016/j.aquaculture.2013.09.023
- Author:
- Wien, Michelle; Oda, Keiji; Sabaté, Joan
- Source:
- Nutrition journal 2014 v.13 no.1 pp. 749
- ISSN:
- 1475-2891
- Subject:
- polyunsaturated fatty acids, etc ; adults; alpha-tocopherol; arginine; blood glucose; blood lipids; body mass index; covariance; diet; energy; fasting; folic acid; foods; glycemic control; magnesium; niacin; noninsulin-dependent diabetes mellitus; nutrient intake; optimal nutrition; patients; peanuts; phytosterols; randomized clinical trials; statistical models; waist circumference; weight control; weight loss; Show all 27 Subjects
- Abstract:
- ... BACKGROUND: According to the American Diabetes Association (ADA), the nutritional goals for patients with type 2 diabetes (T2D) are to achieve an optimal nutrient intake to achieve normoglycemia and a cardioprotective lipid profile. Peanuts are nutrient dense foods that contain high levels of monounsaturated fat (MUFA) and are a natural source of arginine, fiber, phytosterols, resveritrol, niacin, ...
- DOI:
- 10.1186/1475-2891-13-10
- PubMed:
- 24450471
- PubMed Central:
- PMC3902416
- http://dx.doi.org/10.1186/1475-2891-13-10
- Author:
- Pallara, Grazia; Buccioni, Arianna; Pastorelli, Roberta; Minieri, Sara; Mele, Marcello; Rapaccini, Stefano; Messini, Anna; Pauselli, Mariano; Servili, Maurizio; Giovannetti, Luciana; Viti, Carlo
- Source:
- BMC veterinary research 2014 v.10 no.1 pp. 271
- ISSN:
- 1746-6148
- Subject:
- polyunsaturated fatty acids, etc ; Butyrivibrio; Neisseria weaveri; Pasteurellaceae; Ruminobacter amylophilus; bacteria; bacterial communities; biohydrogenation; dairy products; denaturing gradient gel electrophoresis; environmental impact; feeds; hydrogenation; in vitro studies; inoculum; meat; olive oil; olive pomace; polymerase chain reaction; polyphenols; rumen bacteria; rumen fluids; sheep; stearic acid; vaccenic acid; Show all 25 Subjects
- Abstract:
- ... BACKGROUND: Stoned olive pomace (SOP), which represents approximately 50% of the conversion process of olives to olive oil, is largely not utilised and creates costs for its disposal and has negative environmental impacts. In vitro trial experiments were employed to study the effect of feeds integrated with this bio-waste, which is rich in polyphenols, on rumen biohydrogenation, using sheep rumen ...
- DOI:
- 10.1186/s12917-014-0271-y
- PubMed:
- 25424901
- PubMed Central:
- PMC4311430
- http://dx.doi.org/10.1186/s12917-014-0271-y
- Author:
- Ahmed, Abeer A; Balogun, Kayode A; Bykova, Natalia V; Cheema, Sukhinder K
- Source:
- Nutrition & metabolism 2014 v.11 no.1 pp. 580
- ISSN:
- 1743-7075
- Subject:
- polyunsaturated fatty acids, etc ; S-adenosylmethionine; adenosine kinase; aldehyde dehydrogenase; apolipoprotein A-I; diabetes; diet; heart diseases; insulin resistance; malate dehydrogenase; mass spectrometry; mice; nitric oxide synthase; obesity; omega-3 fatty acids; ornithine-oxo-acid transaminase; polyacrylamide gel electrophoresis; protein metabolism; proteomics; tricarboxylic acid cycle; two-dimensional gel electrophoresis; Show all 21 Subjects
- Abstract:
- ... BACKGROUND: Omega-3 polyunsaturated fatty acids (n-3 PUFA) have been shown to alleviate the symptoms of metabolic disorders, such as heart disease, diabetes, obesity and insulin resistance. Several putative mechanisms by which n-3 PUFA elicit beneficial health effects have been proposed; however, there is still a shortage of knowledge on the proteins and pathways that are regulated by n-3 PUFA. ME ...
- DOI:
- 10.1186/1743-7075-11-6
- PubMed:
- 24438320
- PubMed Central:
- PMC3898484
- http://dx.doi.org/10.1186/1743-7075-11-6
- Author:
- Ahsan, Haseeb; Ahad, Amjid; Iqbal, Jahangir; Siddiqui, Waseem A
- Source:
- Nutrition & metabolism 2014 v.11 no.1 pp. 623
- ISSN:
- 1743-7075
- Subject:
- polyunsaturated fatty acids, etc ; alpha-tocopherol; anti-inflammatory activity; antioxidant activity; antioxidants; barley; biosafety; brain; cholesterol; chronic diseases; delta-tocopherol; eicosanoids; gamma-tocopherol; gamma-tocotrienol; humans; lipoproteins; liver; metabolism; nitrogen; nuts; peroxidation; toxicology; transcription factor NF-kappa B; vegetable oil; wheat germ; Show all 25 Subjects
- Abstract:
- ... Tocotrienols, members of the vitamin E family, are natural compounds found in a number of vegetable oils, wheat germ, barley, and certain types of nuts and grains. Like tocopherols, tocotrienols are also of four types viz. alpha, beta, gamma and delta. Unlike tocopherols, tocotrienols are unsaturated and possess an isoprenoid side chain. Tocopherols are lipophilic in nature and are found in associ ...
- DOI:
- 10.1186/1743-7075-11-52
- PubMed:
- 25435896
- PubMed Central:
- PMC4247006
- http://dx.doi.org/10.1186/1743-7075-11-52
- Author:
- Moldal, Torfinn; Løkka, Guro; Wiik-Nielsen, Jannicke; Austbø, Lars; Torstensen, Bente E; Rosenlund, Grethe; Dale, Ole Bendik; Kaldhusdal, Magne; Koppang, Erling Olaf
- Source:
- BMC veterinary research 2014 v.10 no.1 pp. 879
- ISSN:
- 1746-6148
- Subject:
- polyunsaturated fatty acids, etc ; Salmo salar; absorption; carcinogenesis; colitis; colorectal neoplasms; diet; epithelial cells; feeds; fish feeding; fish meal; fish oils; genes; human health; humans; immunohistochemistry; inflammation; ingredients; messenger RNA; morphometry; olive oil; omega-6 fatty acids; rapeseed oil; raw materials; reverse transcriptase polymerase chain reaction; risk; rodents; soybean oil; vegetable oil; Show all 29 Subjects
- Abstract:
- ... BACKGROUND: Fish meal and fish oil are increasingly replaced by ingredients from terrestrial sources in the feeds for farmed salmonids due to expanding production and reduced availability of marine feed raw material. Fish oil that is rich in n-3 polyunsaturated fatty acids is considered beneficial to human health in general and to prevent intestinal inflammation and carcinogenesis in particular. I ...
- DOI:
- 10.1186/1746-6148-10-60
- PubMed:
- 24606841
- PubMed Central:
- PMC3973862
- http://dx.doi.org/10.1186/1746-6148-10-60