Jump to Main Content
- Kim, Kyu Won, et al. Show all 6 Authors
- Biochemical and biophysical research communications 2014 v.444 pp. 63-68
- Western blotting; advanced glycation end products; animal disease models; diabetic retinopathy; endothelial cells; fluorescein; humans; immunohistochemistry; mice; protein kinase C; protein synthesis; retina; tight junctions; vascular endothelial growth factors
- ... To investigate the effect of protein kinase C (PKC)-ζ inhibition on vascular leakage in diabetic retinopathy, streptozotocin-induced diabetic mice were intravitreously injected with siPKC-ζ. According to the fluorescein angiography of the retinal vessels, suppression of PKC-ζ effectively attenuated vascular leakage in diabetic retina. Further evaluation on the retina with western blot analysis and ...