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- De Giglio, Elvira, et al. Show all 8 Authors
- Carbohydrate polymers 2014 v.110 pp. 173-182
- Staphylococcus aureus; X-ray photoelectron spectroscopy; adhesion; antibiotics; cell viability; chitosan; ciprofloxacin; coatings; cross infection; gamma-cyclodextrin; gene expression; high performance liquid chromatography; nanoparticles; particle size; prostheses; titanium; transmission electron microscopy; zeta potential
- ... A novel ciprofloxacin loaded chitosan nanoparticle-based coating onto titanium substrates has been developed and characterized to obtain an orthopaedic implant surface able to in situ release the antibiotic for the prevention of post-operative infections. Ciprofloxacin loaded chitosan nanoparticles were obtained using the combination of sulfobutyl ether-beta-cyclodextrin and gamma-cyclodextrin. Th ...