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- Scrivens, James H., et al. Show all 6 Authors
- Analytical chemistry 2014 v.86 no.21 pp. 10789-10795
- proteins; ions; glycosylation; data collection; high performance liquid chromatography; spectroscopy; dextran; databases; stereoisomers
- ... Glycosylation is one of the most common post-translational modifications occurring in proteins. A detailed structural characterization of the involved carbohydrates, however, is still one of the greatest challenges in modern glycoproteomics, since multiple regio- and stereoisomers with an identical monosaccharide composition may exist. Recently, ion mobility-mass spectrometry (IM-MS), a technique ...
- Scrivens, James
H., et al. Show all 8 Authors
- Journal of Proteome Research 2014 v.13 no.3 pp. 1702-1712
- Culicidae; Semliki Forest virus; arthropods; biogenesis; cell lines; chemical composition; cryo-electron microscopy; dissociation; enzymes; glycoproteins; glycosylation; mass spectrometry; models; polysaccharides; progeny; protein structure; proteome; rodents; virion; virus transmission
- ... Cross-species viral transmission subjects parent and progeny alphaviruses to differential post-translational processing of viral envelope glycoproteins. Alphavirus biogenesis has been extensively studied, and the Semliki Forest virus E1 and E2 glycoproteins have been shown to exhibit differing degrees of processing of N-linked glycans. However the composition of these glycans, including that arisi ...