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- Stenglein, Mark D., et al. Show all 5 Authors
- Genome announcements 2014 v.2 no.5 pp. e00779-14
- Bornavirus; birds; mammals; nucleotide sequences; snakes
- ... Bornaviruses are known to infect mammals and birds, and they have been associated with disease in both groups of animals. Here, we report the genome sequence of a bornavirus identified in a wild-caught Loveridge’s garter snake (Elapsoidea loveridgei). ...
- Stenglein, Mark D., et al. Show all 12 Authors
- mBio 2014 v.5 no.5 pp. e01484-14
- Python regius; RNA; Torovirinae; color; diagnostic techniques; divergent evolution; epithelial cells; genome; metagenomics; new genus; pathogens; respiratory system; respiratory tract diseases; sequence analysis; snakes; virus-like particles; viruses
- ... A severe, sometimes fatal respiratory disease has been observed in captive ball pythons ( Python regius ) since the late 1990s. In order to better understand this disease and its etiology, we collected case and control samples and performed pathological and diagnostic analyses. Electron micrographs revealed filamentous virus-like particles in lung epithelial cells of sick animals. Diagnostic testi ...
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- Stenglein, Mark D., et al. Show all 11 Authors
- Journal of Molecular Biology 2014 v.426 pp. 1452-1468
- Arenaviridae; Corallus; Ebolavirus; Marburg virus; acidification; cell membranes; crystal structure; denaturation; etiology; genome; glycoproteins; pH; viruses
- ... Fusion of the viral and host cell membranes is a necessary first step for infection by enveloped viruses and is mediated by the envelope glycoprotein. The transmembrane subunits from the structurally defined “class I” glycoproteins adopt an α-helical “trimer-of-hairpins” conformation during the fusion pathway. Here, we present our studies on the envelope glycoprotein transmembrane subunit, GP2, of ...
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