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- Shin, Chan Young, et al. Show all 15 Authors
- Life sciences 2013 v.92 no.17-19 pp. 929-937
- Western blotting; astrocytes; brain; casein; cell viability; gene expression; gene expression regulation; glucose; messenger RNA; rats; reverse transcriptase polymerase chain reaction; signal transduction; t-plasminogen activator; translation (genetics)
- ... AIMS: Tissue plasminogen activator (tPA) is an essential neuromodulator whose involvement in multiple functions such as synaptic plasticity, cytokine-like immune function and regulation of cell survival mandates rapid and tight tPA regulation in the brain. We investigated the possibility that a transient metabolic challenge induced by glucose deprivation may affect tPA activity in rat primary astr ...