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1. Nanomechanics of Lipid Encapsulated Microbubbles with Functional Coatings

Author:
Peyman, Sally A.,   et al.   ; Abou-Saleh, Radwa H.; Critchley, Kevin; Evans, Stephen D.; Thomson, Neil H.;     Show all 5 Authors
Source:
Langmuir 2013 v.29 no.12 pp. 4096-4103
ISSN:
1520-5827
Subject:
atomic force microscopy; biocompatibility; coatings; deformation; drugs; lipids; microbubbles; models; plasticity; polyethylene glycol; quantum dots; streptavidin; therapeutics; tissues; ultrasonography
Abstract:
... Microbubbles (MBs) are increasingly being proposed as delivery vehicles for targeted therapeutics, as well as being contrast agents for ultrasound imaging. MBs formed with a lipid shell are promising candidates due to their biocompatibility and the opportunity for surface functionalization, both for specific targeting of tissues and as a means to tune their mechanical response for localized ultras ...
DOI:
10.1021/la304093t