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1. Chrysomycins A–C, antileukemic naphthocoumarins from Streptomyces sporoverrucosus

Author:
Raina, Chandji,   et al.   ; Jain, Shreyans K.; Pathania, Anup S.; Parshad, Rajinder; Ali, Asif; Gupta, Ajai P.; Kushwaha, Manoj; Aravinda, Subrayashastry; Bhushan, Shashi; Bharate, Sandip B.; Vishwakarma, Ram A.;     Show all 11 Authors
Source:
RSC advances 2013 v.3 no.43 pp. 21046-21053
ISSN:
2046-2069
Subject:
DNA damage; Streptomyces; apoptosis; cell lines; cytotoxicity; hills; humans; inhibitory concentration 50; leukemia; neoplasm cells; nuclear magnetic resonance spectroscopy; soil sampling
Abstract:
... Two known naphthocoumarins, chrysomycins A (1) and B (2), along with one new naphthocoumarin chrysomycin C (3) were isolated from the antimicrobial strain of Streptomyces sporoverrucosus (MTCC11715) (isolated from soil samples from the Jammu hills) and characterized. The structure of the new compound 3 was established from 2D-NMR data. Chrysomycins A (1) and B (2) were identified using a strategic ...
DOI:
10.1039/c3ra42884b