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- Hashmi, Sanya; Hashmi, Sarwar, et al. Show all 10 Authors
- Journal of Molecular Biology 2013 v.425 pp. 2641-2655
- Caenorhabditis elegans; apolipoprotein B; beta oxidation; biochemical pathways; cholesterol; dietary fat; energy; fatty acids; genes; homeostasis; human diseases; humans; intestines; liver; mutants; mutation; risk factors; secretion; transcription factors; triacylglycerols; very low density lipoprotein; vitamin D
- ... Lipid metabolism is coordinately regulated through signaling networks that integrate biochemical pathways of fat assimilation, mobilization and utilization. Excessive diversion of fat for storage is a key risk factor for many fat-related human diseases. Dietary lipids are absorbed from the intestines and transported to various organs and tissues to provide energy and maintain lipid homeostasis. In ...
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- Hashmi, Sarwar, et al. Show all 7 Authors
- Nutrition & metabolism 2013 v.10 no.1 pp. 538
- Caenorhabditis elegans; adipose tissue; biosynthesis; brain; cell biology; energy; energy metabolism; fatty acids; genes; genetics; homeostasis; humans; insulin; insulin resistance; intestines; lipid metabolism; liver; metabolic studies; metabolic syndrome; metabolites; models; molecular biology; muscles; neurons; noninsulin-dependent diabetes mellitus; obesity; pathogenesis; public health; risk factors; secretion
- ... Lipid metabolic disorder is a critical risk factor for metabolic syndrome, triggering debilitating diseases like obesity and diabetes. Both obesity and diabetes are the epicenter of important medical issues, representing a major international public health threat. Accumulation of fat in adipose tissue, muscles and liver and/or the defects in their ability to metabolize fatty acids, results in insu ...
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