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- Crawford, Robert W.; Wangdi, Tamding; Spees, Alanna M.; Xavier, Mariana N.; Tsolis, Renée M.; Bäumler, Andreas J.
- mBio 2013 v.4 no.4 pp. e00232-13
- typhoid fever, etc ; Salmonella Typhi; anti-inflammatory activity; colitis; complement; evolution; gastroenteritis; horizontal gene transfer; immune evasion; inflammation; loci; mice; models; multigene family; mutants; pathogenicity islands; pathogens; phenotype; polysaccharides; pseudogenes; serotypes; virulence; Show all 22 Subjects
- ... Expression of capsular polysaccharides is a variable trait often associated with more-virulent forms of a bacterial species. For example, typhoid fever is caused by the capsulated Salmonella enterica serovar Typhi, while nontyphoidal Salmonella serovars associated with gastroenteritis are noncapsulated. Here we show that optimization of the immune evasive properties conferred by the virulence-asso ...
- PubMed Central:
- Yang, Youjun; Wan, Cuixiang; Xu, Hengyi; Wei, Hua
- Vaccine 2013 v.31 no.28 pp. 2930-2936
- typhoid fever, etc ; Salmonella; Western blotting; antibacterial properties; antigens; bacteria; blood serum; cell-mediated immunity; cellular microenvironment; gastroenteritis; human diseases; humans; mice; outer membrane proteins; pathogens; porins; reverse transcriptase polymerase chain reaction; serotypes; vaccines; Show all 19 Subjects
- ... Salmonella is gram-negative flagellated bacteria that can cause food and waterborne gastroenteritis and typhoid fever in humans. Despite the importance of Salmonella infections in human and animal health, the target antigens of Salmonella-specific immunity remain poorly defined, the effectiveness of the currently available vaccines is also limited. Outer membrane proteins (OMPs) of Salmonella have ...