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chemical reactions; chemical structure; piperidines; synthesis
Abstract:
... An expedient regio-, stereo- and product-selective synthesis of novel hybrid heterocyclic systems comprising [1,2-c]oxazolidine, pyrrolidine and piperidine units, in good to excellent yields, has been developed via three-component 1,3-dipolar cycloaddition/annulation domino reactions and concomitant trifluoroacetic acid mediated condensative annulation with paraformaldehyde. These novel structural ...
... Shiga toxin-producing Escherichia coli (STEC) are frequent causes of severe human diseases ranging from diarrhea to hemolytic uremic syndrome. The existing strategy for detection of STEC relies on the unique sorbitol-negative fermentation property of the O157 strains, the most commonly identified serotype has been E. coli O157. It is becoming increasingly evident, however, that numerous non-O157 S ...
Cynodon dactylon; Meleagris gallopavo; Vertisols; continuous cropping; enzyme activity; indigenous species; long term effects; long term experiments; management systems; nutrient availability; pastures; poultry manure; soil management; soil properties; soil quality; turkeys; Texas
Abstract:
... Soil quality assessment is a process for understanding long-term effects of soil and crop management. Our objective was to assess those effects on Vertisols in Texas after 57 yr. Five fields were sampled in 2006: a managed native pasture (NP), two pastures that were previously cropped and then seeded to Coastal bermudagrass [Cynodon dactylon (L.) Pers.] for the past 57 (CB) or 31 (CBTL) yr, and tw ...
... A seven‐year‐old, ovariohysterectomised female dwarf lop rabbit (Oryctolagus cuniculus) was referred with severe swelling and erythema of the mucocutaneous junctions of the lips, nares and vulva. Bilateral, severe periocular dermatitis was also present. Heavy pure growths of a member of the Staphylococcus intermedius group were cultured from nasal and aural swabs and skin biopsies. Other possible ...
acetone; adsorption; analytical methods; chemical structure; crop rotation; edaphic factors; farmers; hexane; methylation; organosilicon compounds; particulates; pest control; pesticides; sediments; soil; ultrasonic treatment; water management; watersheds
Abstract:
... Organic pesticides are difficult compounds to extract from soils and sediments due to their strong affinity for soil particulates. Different pesticide compounds migrate to varying extents in the environment depending on their chemical structures, with effects ranging from strong adsorption to soil particles to rapid dissolution in water. Published methodologies report procedures for extracting and ...
... Craniofrontonasal syndrome (CFNS, MIM #304110) is a rare X-linked dominant developmental disorder that shows paradoxically greater severity in affected females than in affected males. Our female patient with frontonasal dysplasia, craniosynostosis and additional malformations was consistent with CFNS. EFNB1, which encodes a member of the ephrin family of transmembrane ligands for Eph receptor tyro ...
absorption; cell membranes; centrifugation; cortex; cost effectiveness; models; monitoring; pharmacokinetics; rapid methods; spectrometers; tandem mass spectrometry; wastes
Abstract:
... In vitro cell models are easy, reproducible, and cost-effective tools for tracking drug absorption rates and for elucidating related mechanisms. Traditionally, before introduction into an analysis system, samples crossing an in vitro cell membrane usually undergo complicated processes including precipitation, centrifugation, and even filtering. In the current study, a generic, sensitive and rapid ...
... A simple and efficient ultrasound-assisted dispersive liquid–liquid microextraction (UA-DLLME) method has been developed for the determination of seven benzodiazepines (alprazolam, bromazepam, clonazepam, diazepam, lorazepam, lormetazepam and tetrazepam) in human plasma samples. Chloroform and methanol were used as extractant and disperser solvents, respectively. The influence of several variables ...
Brassica oleracea var. italica; amplified fragment length polymorphism; broccoli; cultivars; florets; genome; heat tolerance; linkage groups; quantitative trait loci
Abstract:
... This study identified amplified fragment length polymorphism (AFLP) markers linked to head-related traits in broccoli (Brassica oleracea var. italica) grown in both Winter (W) and Summer (S) in 2008 and in 2009. In total, 227 F₂ plants derived from a cross between the heat-tolerant cultivar ‘Shin-Fa 1208’ (SF), and the heat-sensitive cultivar ‘Green Magic’ (GM), were grown in the field. Seven trai ...
... This paper presents findings from a study of seven Payment for Environmental Service (PES) schemes that assessed impacts on livelihoods and implications for the design of incentive mechanisms for Reducing Emissions from Deforestation and forest Degradation (REDD+). It focuses on two areas of importance to the local impacts of PES and REDD+ schemes: (i) whether tenure and wealth filter access to sc ...
... Concentrations of polycyclic aromatic hydrocarbons (PAHs) were measured in liver tissues of seven species of birds collected from Ahmedabad, India during 2005–2007. All the samples collected were dead as victims of kite flying. Concentrations of ∑PAHs in livers of birds were ranged from 110 ± 32.6 ng/g wet wt (1,078 ± 320 lipid wt) in common myna Acridotheres tristis to 382 ± 90.1 ng/g (2,388 ± 56 ...
Chiara Di Marco; Anna Lavinia Bulotta; Concetta Varetti; Laura Dosa; Angela Michelucci; Fulvia Baldinotti; Daniela Meucci; Cinzia Castagnini; Caterina Lo Rizzo; Giovanni Di Maggio; Paolo Simi; Francesca Mari; Silvano Bertelloni; Alessandra Renieri; Mario Messina
... We report on seven Iraqi patients with 46,XY karyotype and ambiguous genitalia characterized by perineo-scrotal hypospadias, bifid scrotum, clitoris like phallus, palpable testes in inguinal canal and pseudovagina. Patients were raised five as females and two as males. They are all unrelated with the exception of two couples of brothers. The diagnosis of 5-α-reductase-2 deficiency syndrome was fir ...
Sudan dyes; acetone; ambient temperature; dithionite; gas chromatography-mass spectrometry; liquid chromatography; paprika; reducing agents; screening; sodium; standard deviation
Abstract:
... An indirect analytical screening method for Sudan dyes by gas chromatography mass spectrometry was developed as an alternative method to novel liquid chromatography mass spectrometry. Red paprika paste samples were extracted with acetone and centrifuged at room temperature. The supernatant was removed from the solution and buffered. The reduction step is performed chemically with sodium dithionite ...
anaerobic digesters; anaerobic digestion; biodegradability; biogas; chemical oxygen demand; linear models; methane; sewage; sewage sludge; solubilization; uncertainty; wastewater treatment
Abstract:
... Seven mixed sewage sludges from different wastewater treatment plants, which have an anaerobic digester in operation, were evaluated in order to clarify the literature uncertainty with regard to the sewage sludge characterisation and biodegradability. Moreover, a methodology is provided to determine the Anaerobic Digestion Model No. 1 parameters, coefficients and initial state variables as well as ...
... U1A binds U1hpII, a hairpin RNA with a 10-nucleotide loop. A U1A mutant (ΔK50ΔM51) binds U1hpII-derived hairpins with shorter loops, making it an interesting scaffold for engineering or evolving proteins that bind similarly sized disease-related hairpin RNAs. However, a more detailed understanding of complexes involving ΔK50ΔM51 is likely a prerequisite to generating such proteins. Toward this end ...
... An LC–MS/MS method for analyzing seven folates in food was developed and validated. 5-Methyltetrahydrofolate, 5-formyltetrahydrofolate, 10-formylfolic acid, tetrahydrofolate and folic acid were quantified using a stable isotope dilution assay (SIDA) with deuterated analogues as internal standards. Additionally, 10-formyldihydrofolate and 5,10-methenyltetrahydrofolate were quantified using deuterat ...
Human immunodeficiency virus 1; data collection; databases; drug resistance; genome; monitoring; pathogenesis; patients; phylogeny
Abstract:
... To investigate differences in pathogenesis, diagnosis and resistance pathways between HIV-1 subtypes, an accurate subtyping tool for large datasets is needed. We aimed to evaluate the performance of automated subtyping tools to classify the different subtypes and circulating recombinant forms using pol, the most sequenced region in clinical practice. We also present the upgraded version 3 of the R ...
anthocyanins; blueberries; cultivars; developmental stages; fruit yield; fruits; seasonal variation; New Zealand
Abstract:
... This study compares the yields, weights and anthocyanin contents of fruit from a group of seven new cultivars released from the New Zealand blueberry breeding programme and selected for the longest possible combined harvest season. The measured factors were primarily influenced by cultivar, and seasonal variations had relatively minor effects. The late-ripening cultivars ‘Velluto Blue’ and ‘Centra ...
... This research is aimed to develop a nano-sized supramolecular micelle delivery system of cis-dichlorodiammine platinum (II) (CDDP) in order to achieve the passive tumor targeting. Firstly, star-shaped poly (γ-benzyl-l-glutamate) was synthesized by the ring-opening polymerization of γ-benzyl-l-glutamate-N-carboxyanhydride initiated with per-6-amino-β-cyclodextrin. After removal of benzyl groups, β- ...
... Diarrhoea is a common disease which causes pain and may be deadly, especially in developing countries. In Bangladesh, diarrhoeal diseases affect thousands of people every year, and children are especially vulnerable. Bacterial toxins or viral infections are the most common cause of the disease. The diarrhoea outbreaks are often associated with flood affected areas with contaminated drinking water ...