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- Calixto, João B., et al. Show all 5 Authors
- Molecular Immunology 2013 v.54 pp. 482-492
- CD18 antigen; acylglycerol lipase; adhesion; anti-inflammatory activity; cannabinoids; cell adhesion; chemokines; colitis; colon; dextran; fatty acids; gene expression; interleukin-4; macrophages; messenger RNA; mice; myeloperoxidase; oral administration; protein synthesis; triterpenoids; tumor necrosis factors; weight loss
- ... The pentacyclic triterpene α,β-amyrin has been previously reported as an effective compound in the treatment of several inflammatory conditions. Recent evidence indicates that α,β-amyrin displayed its effects through interaction with the cannabinoid pathway. We assessed the anti-inflammatory effects of the α,β-amyrin in the dextran sulfate sodium (DSS)-induced colitis in mice and investigated whet ...
- Calixto, João B., et al. Show all 4 Authors
- Revista Brasileira de Farmacognosia 2013 v.23 no.1 pp. 124-131
- Phyllanthus niruri; anti-inflammatory activity; aqueous solutions; chemical composition; edema; gallic acid; high performance liquid chromatography; leaves; mice; models; oral administration; powders; quantitative analysis; roots; spray drying; stems; synergism
- ... The anti-inflammatory and antiallodynic effects of spray dried powders starting from leaves, stems, roots, the mixture of leaves and stems, as well as the whole plant aqueous solutions of Phyllanthus niruri L., Phyllanthaceae, were assessed. Gallic acid, used as chemical marker, was quantified by HPLC in the spray dried powders. Carrageenan-induced inflammatory and allodynic responses in the mouse ...