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- Diaz-San Segundo, Fayna, et al. Show all 10 Authors
- Journal of virology 2013 v.87 no.10 pp. 5447
- Foot-and-mouth disease virus; Venezuelan equine encephalitis virus; cattle; death; encephalitis; gene induction; genes; green fluorescent protein; horses; humans; immunization; interferons; lethal dose; livestock and meat industry; mice; replicon; swine; viruses
- ... We have previously shown that delivery of the porcine type I interferon gene (poIFN-α/β) with a replication-defective human adenovirus vector (adenovirus 5 [Ad5]) can sterilely protect swine challenged with foot-and-mouth disease virus (FMDV) 1 day later. However, the need of relatively high doses of Ad5 limits the applicability of such a control strategy in the livestock industry. Venezuelan equi ...
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